VEGF-Related Germinal Polymorphisms May Identify a Subgroup of Breast Cancer Patients with Favorable Outcome under Bevacizumab-Based Therapy-A Message from COMET, a French Unicancer Multicentric Study.
Pharmaceuticals (Basel, Switzerland)
J Gal, G Milano, P Brest, N Ebran, J Gilhodes, L Llorca, C Dubot, G Romieu, I Desmoulins, E Brain, A Goncalves, JM Ferrero, PH Cottu, M Debled, O Tredan, E Chamorey, MC Merlano, J Lemonnier, MC Etienne-Grimaldi, JY Pierga
Clinical outcomes and safety of apatinib monotherapy in the treatment of patients with advanced epithelial ovarian carcinoma who progressed after standard regimens and the analysis of the VEGFR2 polymorphism.
Oncology Letters
Z Yan, YY Gu, XD Hu, Q Zhao, HL Kang, M Wang, W Duan, Y Guan
Polymorphisms in the Angiogenesis-Related Genes EFNB2, MMP2 and JAG1 Are Associated with Survival of Colorectal Cancer Patients.
International Journal Of Molecular Sciences
D Scherer, H Deutelmoser, Y Balavarca, R Toth, N Habermann, K Buck, EJ Kap, A Botma, P Seibold, L Jansen, J Lorenzo Bermejo, K Weigl, A Benner, M Hoffmeister, A Ulrich, H Brenner, B Burwinkel, J Chang-Claude, CM Ulrich
Molecular Bases of Drug Resistance in Hepatocellular Carcinoma.
Cancers
JJG Marin, RIR Macias, MJ Monte, MR Romero, M Asensio, A Sanchez-Martin, C Cives-Losada, AG Temprano, R Espinosa-Escudero, M Reviejo, LH Bohorquez, O Briz
Combination of variations in inflammation- and endoplasmic reticulum-associated genes as putative biomarker for bevacizumab response in KRAS wild-type colorectal cancer.
Scientific Reports
A Barat, D Smeets, B Moran, W Zhang, S Cao, S Das, R Klinger, J Betge, V Murphy, O Bacon, EW Kay, NCT Van Grieken, HMW Verheul, T Gaiser, N Schulte, MP Ebert, B Fender, BT Hennessy, DA McNamara, D O'Connor, WM Gallagher, C Cremolini, F Loupakis, A Parikh, C Mancao, B Ylstra, D Lambrechts, HJ Lenz, AT Byrne, JHM Prehn
Association between Single Nucleotide Polymorphisms in Cardiovascular Developmental Critical Genes and Hypertension: A Propensity Score Matching Analysis.
International Journal Of Hypertension
Z Zhao, C Gong, Y Gao, X Liu, S Wu, H Zhao, X Wang, H Liu, C Xiao, J Liu, J Li, Y He
Dual VEGF inhibition with sorafenib and bevacizumab as salvage therapy in metastatic colorectal cancer: results of the phase II North Central Cancer Treatment Group study N054C (Alliance).
Therapeutic Advances In Medical Oncology
H Xie, JM Lafky, BW Morlan, PJ Stella, SR Dakhil, GG Gross, WS Loui, JM Hubbard, SR Alberts, A Grothey
POT1 and Damage Response Malfunction Trigger Acquisition of Somatic Activating Mutations in the VEGF Pathway in Cardiac Angiosarcomas.
Journal Of The American Heart Association
O Calvete, P Garcia-Pavia, F Domínguez, L Mosteiro, L Pérez-Cabornero, D Cantalapiedra, E Zorio, T Ramón Y Cajal, MG Crespo-Leiro, Á Teulé, C Lázaro, MM Morente, M Urioste, J Benitez
Evaluation of associations between genetically predicted circulating protein biomarkers and breast cancer risk.
International Journal Of Cancer
X Shu, J Bao, L Wu, J Long, XO Shu, X Guo, Y Yang, K Michailidou, MK Bolla, Q Wang, J Dennis, IL Andrulis, JE Castelao, T Dörk, M Gago-Dominguez, M García-Closas, GG Giles, A Lophatananon, K Muir, H Olsson, G Rennert, E Saloustros, RJ Scott, MC Southey, PDP Pharoah, RL Milne, P Kraft, J Simard, DF Easton, W Zheng
Phase III Trial of Adjuvant Sunitinib in Patients with High-Risk Renal Cell Carcinoma: Exploratory Pharmacogenomic Analysis.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
DJ George, JF Martini, M Staehler, RJ Motzer, A Magheli, F Donskov, B Escudier, S Li, M Casey, O Valota, B Laguerre, AJ Pantuck, HS Pandha, A Patel, M Lechuga, A Ravaud
Plasma levels of soluble VEGF receptor isoforms, circulating pterins and VEGF system SNPs as prognostic biomarkers in patients with acute coronary syndromes.
Bmc Cardiovascular Disorders
ECA Marks, TM Wilkinson, CM Frampton, L Skelton, AP Pilbrow, TG Yandle, CJ Pemberton, RN Doughty, GA Whalley, CJ Ellis, RW Troughton, MC Owen, NR Pattinson, VA Cameron, AM Richards, SP Gieseg, BR Palmer
Integrated Genomic Analysis of Hürthle Cell Cancer Reveals Oncogenic Drivers, Recurrent Mitochondrial Mutations, and Unique Chromosomal Landscapes.
Cancer Cell
I Ganly, V Makarov, S Deraje, Y Dong, E Reznik, V Seshan, G Nanjangud, S Eng, P Bose, F Kuo, LGT Morris, I Landa, PB Carrillo Albornoz, N Riaz, YE Nikiforov, K Patel, C Umbricht, M Zeiger, E Kebebew, E Sherman, R Ghossein, JA Fagin, TA Chan
Impact of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) single nucleotide polymorphisms on outcome in gastroenteropancreatic neuroendocrine neoplasms.
Plos One
R Berardi, M Torniai, S Partelli, C Rubini, S Pagliaretta, A Savini, V Polenta, M Santoni, R Giampieri, S Onorati, F Barucca, A Murrone, F Bianchi, M Falconi
Determination of VEGFR-2 (KDR) 604A>G Polymorphism in Pancreatic Disorders.
International Journal Of Molecular Sciences
V Pădureanu, MV Boldeanu, I Streaţă, MG Cucu, I Siloşi, L Boldeanu, M Bogdan, AŞ Enescu, M Forţofoiu, A Enescu, EM Dumitrescu, D Alexandru, VM Şurlin, MC Forţofoiu, IO Petrescu, F Petrescu, M Ioana, ME Ciurea, A Săftoiu
Functional PTGS2 polymorphism-based models as novel predictive markers in metastatic renal cell carcinoma patients receiving first-line sunitinib.
Scientific Reports
A Cebrián, T Gómez Del Pulgar, MJ Méndez-Vidal, ML Gonzálvez, N Lainez, D Castellano, I García-Carbonero, E Esteban, MI Sáez, R Villatoro, C Suárez, A Carrato, J Munárriz-Ferrándiz, L Basterrechea, M García-Alonso, JL González-Larriba, B Perez-Valderrama, J Cruz-Jurado, A González Del Alba, F Moreno, G Reynés, M Rodríguez-Remírez, V Boni, I Mahillo-Fernández, Y Martin, A Viqueira, J García-Foncillas
Germline Genetic Variants in TEK, ANGPT1, ANGPT2, MMP9, FGF2 and VEGFA Are Associated with Pathologic Complete Response to Bevacizumab in Breast Cancer Patients.
Plos One
I Makhoul, VK Todorova, ER Siegel, SW Erickson, I Dhakal, VR Raj, JY Lee, MS Orloff, RJ Griffin, RS Henry-Tillman, S Klimberg, LF Hutchins, SA Kadlubar
Preliminary data of VEGF-A and VEGFR-2 polymorphisms as predictive factors of radiological response and clinical outcome in iodine-refractory differentiated thyroid cancer treated with sorafenib.
Endocrine
V Marotta, C Sciammarella, M Capasso, A Testori, C Pivonello, MG Chiofalo, R Pivonello, L Pezzullo, G Botti, A Colao, A Faggiano
Germline Polymorphisms of the VEGF Pathway Predict Recurrence in Nonadvanced Differentiated Thyroid Cancer.
The Journal Of Clinical Endocrinology And Metabolism
V Marotta, C Sciammarella, M Capasso, A Testori, C Pivonello, MG Chiofalo, C Gambardella, M Grasso, A Antonino, A Annunziata, PE Macchia, R Pivonello, L Santini, G Botti, S Losito, L Pezzullo, A Colao, A Faggiano
No associations of a set of SNPs in the Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinase (MMP) genes with survival of colorectal cancer patients.
Cancer Medicine
LA Dan, S Werdyani, J Xu, K Shestopaloff, A Hyde, E Dicks, B Younghusband, J Green, P Parfrey, W Xu, S Savas
Development and clinical application of an integrative genomic approach to personalized cancer therapy.
Genome Medicine
AV Uzilov, W Ding, MY Fink, Y Antipin, AS Brohl, C Davis, CY Lau, C Pandya, H Shah, Y Kasai, J Powell, M Micchelli, R Castellanos, Z Zhang, M Linderman, Y Kinoshita, M Zweig, K Raustad, K Cheung, D Castillo, M Wooten, I Bourzgui, LC Newman, G Deikus, B Mathew, J Zhu, BS Glicksberg, AS Moe, J Liao, L Edelmann, JT Dudley, RG Maki, A Kasarskis, RF Holcombe, M Mahajan, K Hao, B Reva, J Longtine, D Starcevic, R Sebra, MJ Donovan, S Li, EE Schadt, R Chen
Role of HIF1A, VEGFA and VEGFR2 SNPs in the Susceptibility and Progression of COPD in a Spanish Population.
Plos One
R Baz-Dávila, A Espinoza-Jiménez, Mdel C Rodríguez-Pérez, J Zulueta, N Varo, Á Montejo, D Almeida-González, A Aguirre-Jaime, E Córdoba-Lanús, C Casanova
Angiogenesis genotyping and clinical outcome during regorafenib treatment in metastatic colorectal cancer patients.
Scientific Reports
R Giampieri, L Salvatore, M Del Prete, T Prochilo, M D'Anzeo, C Loretelli, F Loupakis, G Aprile, E Maccaroni, K Andrikou, M Bianconi, A Bittoni, L Faloppi, L Demurtas, R Montironi, M Scarpelli, A Falcone, A Zaniboni, M Scartozzi, S Cascinu
The influence of genetic variants of sorafenib on clinical outcomes and toxic effects in patients with advanced renal cell carcinoma.
Scientific Reports
C Qin, Q Cao, P Li, S Wang, J Wang, M Wang, H Chu, L Zhou, X Li, D Ye, H Zhang, Y Huang, B Dong, X Sun, Q Zou, H Cai, L Sun, J Zhu, F Liu, J Ji, L Cui, X Wang, H Zhou, H Zhao, B Wu, J Chen, M Jiang, Z Zhang, P Shao, X Ju, C Yin
Vascular endothelial growth factor pathway in endometriosis: genetic variants and plasma biomarkers.
Fertility And Sterility
A Vodolazkaia, BT Yesilyurt, CM Kyama, A Bokor, D Schols, D Huskens, C Meuleman, K Peeraer, C Tomassetti, X Bossuyt, D Lambrechts, T D'Hooghe, A Fassbender
Genetic interaction of P2X7 receptor and VEGFR-2 polymorphisms identifies a favorable prognostic profile in prostate cancer patients.
Oncotarget
A Solini, V Simeon, L Derosa, P Orlandi, C Rossi, A Fontana, L Galli, T Di Desidero, A Fioravanti, S Lucchesi, L Coltelli, L Ginocchi, G Allegrini, R Danesi, A Falcone, G Bocci
Identification of IDUA and WNT16 Phosphorylation-Related Non-Synonymous Polymorphisms for Bone Mineral Density in Meta-Analyses of Genome-Wide Association Studies.
Journal Of Bone And Mineral Research : The Official Journal Of The American Society For Bone And Mineral Research
T Niu, N Liu, X Yu, M Zhao, HJ Choi, PJ Leo, MA Brown, L Zhang, YF Pei, H Shen, H He, X Fu, S Lu, XD Chen, LJ Tan, TL Yang, Y Guo, NH Cho, J Shen, YF Guo, GC Nicholson, RL Prince, JA Eisman, G Jones, PN Sambrook, Q Tian, XZ Zhu, CJ Papasian, EL Duncan, AG Uitterlinden, CS Shin, S Xiang, HW Deng
Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy.
Oncotarget
R Berardi, A Brunelli, S Pagliaretta, V Paolucci, A Conti, G Goteri, M Refai, C Pompili, G Marcantognini, F Morgese, Z Ballatore, A Savini, M De Lisa, M Caramanti, M Santoni, A Zizzi, F Piva, P Mazzanti, A Onofri, A Sabbatini, M Scarpelli, S Cascinu
Genetic association study of coronary collateral circulation in patients with coronary artery disease using 22 single nucleotide polymorphisms corresponding to 10 genes involved in postischemic neovascularization.
Bmc Cardiovascular Disorders
J Duran, PS Olavarría, M Mola, V Götzens, J Carballo, EM Pelegrina, M Petit, O Abdul-Jawad, I Otaegui, BG del Blanco, D García-Dorado, J Reig, A Cordero, JM de Anta
Publication Date: 2015-05-12
Variant appearance in text: KDR: Val297Ile; rs2305948
IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma.
British Journal Of Cancer
CF Xu, T Johnson, J Garcia-Donas, TK Choueiri, CN Sternberg, ID Davis, N Bing, KC Deen, Z Xue, L McCann, E Esteban, JC Whittaker, CF Spraggs, C Rodríguez-Antona, LN Pandite, RJ Motzer
Publication Date: 2015-03-31
Variant appearance in text: VEGFR2: V297I; rs2305948