Development and validation of a multivariable genotype-informed gestational diabetes prediction algorithm for clinical use in the Mexican population: insights into susceptibility mechanisms.
Bmj Open Diabetes Research & Care
Zulueta, Mirella M; Gallardo-Rincón, Héctor H; Martinez-Juarez, Luis Alberto LA; Lomelin-Gascon, Julieta J; Ortega-Montiel, Janinne J; Montoya, Alejandra A; Mendizabal, Leire L; Arregi, Maddi M; Martinez-Martinez, María de Los Angeles MLA; Camarillo Romero, Eneida Del Socorro EDS; Mendieta Zerón, Hugo H; Garduño García, José de Jesús JJ; Simón, Laureano L; Tapia-Conyer, Roberto R
Genetic variants for prediction of gestational diabetes mellitus and modulation of susceptibility by a nutritional intervention based on a Mediterranean diet.
Frontiers In Endocrinology
Ramos-Levi, Ana A; Barabash, Ana A; Valerio, Johanna J; García de la Torre, Nuria N; Mendizabal, Leire L; Zulueta, Mirella M; de Miguel, Maria Paz MP; Diaz, Angel A; Duran, Alejandra A; Familiar, Cristina C; Jimenez, Inés I; Del Valle, Laura L; Melero, Veronica V; Moraga, Inmaculada I; Herraiz, Miguel A MA; Torrejon, María José MJ; Arregi, Maddi M; Simón, Laureano L; Rubio, Miguel A MA; Calle-Pascual, Alfonso L AL
Pharmacogenetic association of diabetes-associated genetic risk score with rapid progression of coronary artery calcification following treatment with HMG-CoA-reductase inhibitors -results of the Heinz Nixdorf Recall Study.
Naunyn-Schmiedeberg'S Archives Of Pharmacology
Pechlivanis, Sonali S; Jung, Dominik D; Moebus, Susanne S; Lehmann, Nils N; Mahabadi, Amir A AA; Hoffmann, Per P; Erbel, Raimund R; Nöthen, Markus M MM; Bachmann, Hagen S HS
Genetic factors and risk of type 2 diabetes among women with a history of gestational diabetes: findings from two independent populations.
Bmj Open Diabetes Research & Care
Li, Mengying M; Rahman, Mohammad L ML; Wu, Jing J; Ding, Ming M; Chavarro, Jorge E JE; Lin, Yuan Y; Ley, Sylvia H SH; Bao, Wei W; Grunnet, Louise G LG; Hinkle, Stefanie N SN; Thuesen, Anne Cathrine B ACB; Yeung, Edwina E; Gore-Langton, Robert E RE; Sherman, Seth S; Hjort, Line L; Kampmann, Freja Bach FB; Bjerregaard, Anne Ahrendt AA; Damm, Peter P; Tekola-Ayele, Fasil F; Liu, Aiyi A; Mills, James L JL; Vaag, Allan A; Olsen, Sjurdur F SF; Hu, Frank B FB; Zhang, Cuilin C
Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis.
Bmj (Clinical Research Ed.)
Merino, Jordi J; Guasch-Ferré, Marta M; Ellervik, Christina C; Dashti, Hassan S HS; Sharp, Stephen J SJ; Wu, Peitao P; Overvad, Kim K; Sarnowski, Chloé C; Kuokkanen, Mikko M; Lemaitre, Rozenn N RN; Justice, Anne E AE; Ericson, Ulrika U; Braun, Kim V E KVE; Mahendran, Yuvaraj Y; Frazier-Wood, Alexis C AC; Sun, Dianjianyi D; Chu, Audrey Y AY; Tanaka, Toshiko T; Luan, Jian'an J; Hong, Jaeyoung J; Tjønneland, Anne A; Ding, Ming M; Lundqvist, Annamari A; Mukamal, Kenneth K; Rohde, Rebecca R; Schulz, Christina-Alexandra CA; Franco, Oscar H OH; Grarup, Niels N; Chen, Yii-Der Ida YI; Bazzano, Lydia L; Franks, Paul W PW; Buring, Julie E JE; Langenberg, Claudia C; Liu, Ching-Ti CT; Hansen, Torben T; Jensen, Majken K MK; Sääksjärvi, Katri K; Psaty, Bruce M BM; Young, Kristin L KL; Hindy, George G; Sandholt, Camilla Helene CH; Ridker, Paul M PM; Ordovas, Jose M JM; Meigs, James B JB; Pedersen, Oluf O; Kraft, Peter P; Perola, Markus M; North, Kari E KE; Orho-Melander, Marju M; Voortman, Trudy T; Toft, Ulla U; Rotter, Jerome I JI; Qi, Lu L; Forouhi, Nita G NG; Mozaffarian, Dariush D; Sørensen, Thorkild I A TIA; Stampfer, Meir J MJ; Männistö, Satu S; Selvin, Elizabeth E; Imamura, Fumiaki F; Salomaa, Veikko V; Hu, Frank B FB; Wareham, Nick J NJ; Dupuis, Josée J; Smith, Caren E CE; Kilpeläinen, Tuomas O TO; Chasman, Daniel I DI; Florez, Jose C JC
Blood-based analysis of type-2 diabetes mellitus susceptibility genes identifies specific transcript variants with deregulated expression and association with disease risk.
Scientific Reports
Christodoulou, Maria-Ioanna MI; Avgeris, Margaritis M; Kokkinopoulou, Ioanna I; Maratou, Eirini E; Mitrou, Panayota P; Kontos, Christos K CK; Pappas, Efthimios E; Boutati, Eleni E; Scorilas, Andreas A; Fragoulis, Emmanuel G EG
Influence of genetic ancestry and socioeconomic status on type 2 diabetes in the diverse Colombian populations of Chocó and Antioquia.
Scientific Reports
Chande, Aroon T AT; Rowell, Jessica J; Rishishwar, Lavanya L; Conley, Andrew B AB; Norris, Emily T ET; Valderrama-Aguirre, Augusto A; Medina-Rivas, Miguel A MA; Jordan, I King IK
A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants.
Diabetes
Wood, Andrew R AR; Jonsson, Anna A; Jackson, Anne U AU; Wang, Nan N; van Leewen, Nienke N; Palmer, Nicholette D ND; Kobes, Sayuko S; Deelen, Joris J; Boquete-Vilarino, Lorena L; Paananen, Jussi J; Stančáková, Alena A; Boomsma, Dorret I DI; de Geus, Eco J C EJC; Eekhoff, Elisabeth M W EMW; Fritsche, Andreas A; Kramer, Mark M; Nijpels, Giel G; Simonis-Bik, Annemarie A; van Haeften, Timon W TW; Mahajan, Anubha A; Boehnke, Michael M; Bergman, Richard N RN; Tuomilehto, Jaakko J; Collins, Francis S FS; Mohlke, Karen L KL; Banasik, Karina K; Groves, Christopher J CJ; McCarthy, Mark I MI; , ; Pearson, Ewan R ER; Natali, Andrea A; Mari, Andrea A; Buchanan, Thomas A TA; Taylor, Kent D KD; Xiang, Anny H AH; Gjesing, Anette P AP; Grarup, Niels N; Eiberg, Hans H; Pedersen, Oluf O; Chen, Yii-Derr YD; Laakso, Markku M; Norris, Jill M JM; Smith, Ulf U; Wagenknecht, Lynne E LE; Baier, Leslie L; Bowden, Donald W DW; Hansen, Torben T; Walker, Mark M; Watanabe, Richard M RM; 't Hart, Leen M LM; Hanson, Robert L RL; Frayling, Timothy M TM
Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
Diabetes
Qi, Qibin Q; Stilp, Adrienne M AM; Sofer, Tamar T; Moon, Jee-Young JY; Hidalgo, Bertha B; Szpiro, Adam A AA; Wang, Tao T; Ng, Maggie C Y MCY; Guo, Xiuqing X; , ; Chen, Yii-Der Ida YI; Taylor, Kent D KD; Aviles-Santa, M Larissa ML; Papanicolaou, George G; Pankow, James S JS; Schneiderman, Neil N; Laurie, Cathy C CC; Rotter, Jerome I JI; Kaplan, Robert C RC
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
Nature Genetics
Gaulton, Kyle J KJ; Ferreira, Teresa T; Lee, Yeji Y; Raimondo, Anne A; Mägi, Reedik R; Reschen, Michael E ME; Mahajan, Anubha A; Locke, Adam A; Rayner, N William NW; Robertson, Neil N; Scott, Robert A RA; Prokopenko, Inga I; Scott, Laura J LJ; Green, Todd T; Sparso, Thomas T; Thuillier, Dorothee D; Yengo, Loic L; Grallert, Harald H; Wahl, Simone S; Frånberg, Mattias M; Strawbridge, Rona J RJ; Kestler, Hans H; Chheda, Himanshu H; Eisele, Lewin L; Gustafsson, Stefan S; Steinthorsdottir, Valgerdur V; Thorleifsson, Gudmar G; Qi, Lu L; Karssen, Lennart C LC; van Leeuwen, Elisabeth M EM; Willems, Sara M SM; Li, Man M; Chen, Han H; Fuchsberger, Christian C; Kwan, Phoenix P; Ma, Clement C; Linderman, Michael M; Lu, Yingchang Y; Thomsen, Soren K SK; Rundle, Jana K JK; Beer, Nicola L NL; van de Bunt, Martijn M; Chalisey, Anil A; Kang, Hyun Min HM; Voight, Benjamin F BF; Abecasis, Gonçalo R GR; Almgren, Peter P; Baldassarre, Damiano D; Balkau, Beverley B; Benediktsson, Rafn R; Blüher, Matthias M; Boeing, Heiner H; Bonnycastle, Lori L LL; Bottinger, Erwin P EP; Burtt, Noël P NP; Carey, Jason J; Charpentier, Guillaume G; Chines, Peter S PS; Cornelis, Marilyn C MC; Couper, David J DJ; Crenshaw, Andrew T AT; van Dam, Rob M RM; Doney, Alex S F AS; Dorkhan, Mozhgan M; Edkins, Sarah S; Eriksson, Johan G JG; Esko, Tonu T; Eury, Elodie E; Fadista, João J; Flannick, Jason J; Fontanillas, Pierre P; Fox, Caroline C; Franks, Paul W PW; Gertow, Karl K; Gieger, Christian C; Gigante, Bruna B; Gottesman, Omri O; Grant, George B GB; Grarup, Niels N; Groves, Christopher J CJ; Hassinen, Maija M; Have, Christian T CT; Herder, Christian C; Holmen, Oddgeir L OL; Hreidarsson, Astradur B AB; Humphries, Steve E SE; Hunter, David J DJ; Jackson, Anne U AU; Jonsson, Anna A; Jørgensen, Marit E ME; Jørgensen, Torben T; Kao, Wen-Hong L WH; Kerrison, Nicola D ND; Kinnunen, Leena L; Klopp, Norman N; Kong, Augustine A; Kovacs, Peter P; Kraft, Peter P; Kravic, Jasmina J; Langford, Cordelia C; Leander, Karin K; Liang, Liming L; Lichtner, Peter P; Lindgren, Cecilia M CM; Lindholm, Eero E; Linneberg, Allan A; Liu, Ching-Ti CT; Lobbens, Stéphane S; Luan, Jian'an J; Lyssenko, Valeriya V; Männistö, Satu S; McLeod, Olga O; Meyer, Julia J; Mihailov, Evelin E; Mirza, Ghazala G; Mühleisen, Thomas W TW; Müller-Nurasyid, Martina M; Navarro, Carmen C; Nöthen, Markus M MM; Oskolkov, Nikolay N NN; Owen, Katharine R KR; Palli, Domenico D; Pechlivanis, Sonali S; Peltonen, Leena L; Perry, John R B JR; Platou, Carl G P CG; Roden, Michael M; Ruderfer, Douglas D; Rybin, Denis D; van der Schouw, Yvonne T YT; Sennblad, Bengt B; Sigurðsson, Gunnar G; Stančáková, Alena A; Steinbach, Gerald G; Storm, Petter P; Strauch, Konstantin K; Stringham, Heather M HM; Sun, Qi Q; Thorand, Barbara B; Tikkanen, Emmi E; Tonjes, Anke A; Trakalo, Joseph J; Tremoli, Elena E; Tuomi, Tiinamaija T; Wennauer, Roman R; Wiltshire, Steven S; Wood, Andrew R AR; Zeggini, Eleftheria E; Dunham, Ian I; Birney, Ewan E; Pasquali, Lorenzo L; Ferrer, Jorge J; Loos, Ruth J F RJ; Dupuis, Josée J; Florez, Jose C JC; Boerwinkle, Eric E; Pankow, James S JS; van Duijn, Cornelia C; Sijbrands, Eric E; Meigs, James B JB; Hu, Frank B FB; Thorsteinsdottir, Unnur U; Stefansson, Kari K; Lakka, Timo A TA; Rauramaa, Rainer R; Stumvoll, Michael M; Pedersen, Nancy L NL; Lind, Lars L; Keinanen-Kiukaanniemi, Sirkka M SM; Korpi-Hyövälti, Eeva E; Saaristo, Timo E TE; Saltevo, Juha J; Kuusisto, Johanna J; Laakso, Markku M; Metspalu, Andres A; Erbel, Raimund R; Jöcke, Karl-Heinz KH; Moebus, Susanne S; Ripatti, Samuli S; Salomaa, Veikko V; Ingelsson, Erik E; Boehm, Bernhard O BO; Bergman, Richard N RN; Collins, Francis S FS; Mohlke, Karen L KL; Koistinen, Heikki H; Tuomilehto, Jaakko J; Hveem, Kristian K; Njølstad, Inger I; Deloukas, Panagiotis P; Donnelly, Peter J PJ; Frayling, Timothy M TM; Hattersley, Andrew T AT; de Faire, Ulf U; Hamsten, Anders A; Illig, Thomas T; Peters, Annette A; Cauchi, Stephane S; Sladek, Rob R; Froguel, Philippe P; Hansen, Torben T; Pedersen, Oluf O; Morris, Andrew D AD; Palmer, Collin N A CN; Kathiresan, Sekar S; Melander, Olle O; Nilsson, Peter M PM; Groop, Leif C LC; Barroso, Inês I; Langenberg, Claudia C; Wareham, Nicholas J NJ; O'Callaghan, Christopher A CA; Gloyn, Anna L AL; Altshuler, David D; Boehnke, Michael M; Teslovich, Tanya M TM; McCarthy, Mark I MI; Morris, Andrew P AP; ,
A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease.
Nature Communications
Ahmad, Omar S OS; Morris, John A JA; Mujammami, Muhammad M; Forgetta, Vincenzo V; Leong, Aaron A; Li, Rui R; Turgeon, Maxime M; Greenwood, Celia M T CM; Thanassoulis, George G; Meigs, James B JB; Sladek, Robert R; Richards, J Brent JB
Sixty-five common genetic variants and prediction of type 2 diabetes.
Diabetes
Talmud, Philippa J PJ; Cooper, Jackie A JA; Morris, Richard W RW; Dudbridge, Frank F; Shah, Tina T; Engmann, Jorgen J; Dale, Caroline C; White, Jon J; McLachlan, Stela S; Zabaneh, Delilah D; Wong, Andrew A; Ong, Ken K KK; Gaunt, Tom T; Holmes, Michael V MV; Lawlor, Debbie A DA; Richards, Marcus M; Hardy, Rebecca R; Kuh, Diana D; Wareham, Nicholas N; Langenberg, Claudia C; Ben-Shlomo, Yoav Y; Wannamethee, S Goya SG; Strachan, Mark W J MW; Kumari, Meena M; Whittaker, John C JC; Drenos, Fotios F; Kivimaki, Mika M; Hingorani, Aroon D AD; Price, Jacqueline F JF; Humphries, Steve E SE; ,
Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study.
Plos Medicine
Langenberg, Claudia C; Sharp, Stephen J SJ; Franks, Paul W PW; Scott, Robert A RA; Deloukas, Panos P; Forouhi, Nita G NG; Froguel, Philippe P; Groop, Leif C LC; Hansen, Torben T; Palla, Luigi L; Pedersen, Oluf O; Schulze, Matthias B MB; Tormo, Maria-Jose MJ; Wheeler, Eleanor E; Agnoli, Claudia C; Arriola, Larraitz L; Barricarte, Aurelio A; Boeing, Heiner H; Clarke, Geraldine M GM; Clavel-Chapelon, Françoise F; Duell, Eric J EJ; Fagherazzi, Guy G; Kaaks, Rudolf R; Kerrison, Nicola D ND; Key, Timothy J TJ; Khaw, Kay Tee KT; Kröger, Janine J; Lajous, Martin M; Morris, Andrew P AP; Navarro, Carmen C; Nilsson, Peter M PM; Overvad, Kim K; Palli, Domenico D; Panico, Salvatore S; Quirós, J Ramón JR; Rolandsson, Olov O; Sacerdote, Carlotta C; Sánchez, María-José MJ; Slimani, Nadia N; Spijkerman, Annemieke M W AM; Tumino, Rosario R; van der A, Daphne L DL; van der Schouw, Yvonne T YT; Barroso, Inês I; McCarthy, Mark I MI; Riboli, Elio E; Wareham, Nicholas J NJ
Polygenic type 2 diabetes prediction at the limit of common variant detection.
Diabetes
Vassy, Jason L JL; Hivert, Marie-France MF; Porneala, Bianca B; Dauriz, Marco M; Florez, Jose C JC; Dupuis, Josée J; Siscovick, David S DS; Fornage, Myriam M; Rasmussen-Torvik, Laura J LJ; Bouchard, Claude C; Meigs, James B JB
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
Nature Genetics
Morris, Andrew P AP; Voight, Benjamin F BF; Teslovich, Tanya M TM; Ferreira, Teresa T; Segrè, Ayellet V AV; Steinthorsdottir, Valgerdur V; Strawbridge, Rona J RJ; Khan, Hassan H; Grallert, Harald H; Mahajan, Anubha A; Prokopenko, Inga I; Kang, Hyun Min HM; Dina, Christian C; Esko, Tonu T; Fraser, Ross M RM; Kanoni, Stavroula S; Kumar, Ashish A; Lagou, Vasiliki V; Langenberg, Claudia C; Luan, Jian'an J; Lindgren, Cecilia M CM; Müller-Nurasyid, Martina M; Pechlivanis, Sonali S; Rayner, N William NW; Scott, Laura J LJ; Wiltshire, Steven S; Yengo, Loic L; Kinnunen, Leena L; Rossin, Elizabeth J EJ; Raychaudhuri, Soumya S; Johnson, Andrew D AD; Dimas, Antigone S AS; Loos, Ruth J F RJ; Vedantam, Sailaja S; Chen, Han H; Florez, Jose C JC; Fox, Caroline C; Liu, Ching-Ti CT; Rybin, Denis D; Couper, David J DJ; Kao, Wen Hong L WH; Li, Man M; Cornelis, Marilyn C MC; Kraft, Peter P; Sun, Qi Q; van Dam, Rob M RM; Stringham, Heather M HM; Chines, Peter S PS; Fischer, Krista K; Fontanillas, Pierre P; Holmen, Oddgeir L OL; Hunt, Sarah E SE; Jackson, Anne U AU; Kong, Augustine A; Lawrence, Robert R; Meyer, Julia J; Perry, John R B JR; Platou, Carl G P CG; Potter, Simon S; Rehnberg, Emil E; Robertson, Neil N; Sivapalaratnam, Suthesh S; Stančáková, Alena A; Stirrups, Kathleen K; Thorleifsson, Gudmar G; Tikkanen, Emmi E; Wood, Andrew R AR; Almgren, Peter P; Atalay, Mustafa M; Benediktsson, Rafn R; Bonnycastle, Lori L LL; Burtt, Noël N; Carey, Jason J; Charpentier, Guillaume G; Crenshaw, Andrew T AT; Doney, Alex S F AS; Dorkhan, Mozhgan M; Edkins, Sarah S; Emilsson, Valur V; Eury, Elodie E; Forsen, Tom T; Gertow, Karl K; Gigante, Bruna B; Grant, George B GB; Groves, Christopher J CJ; Guiducci, Candace C; Herder, Christian C; Hreidarsson, Astradur B AB; Hui, Jennie J; James, Alan A; Jonsson, Anna A; Rathmann, Wolfgang W; Klopp, Norman N; Kravic, Jasmina J; Krjutškov, Kaarel K; Langford, Cordelia C; Leander, Karin K; Lindholm, Eero E; Lobbens, Stéphane S; Männistö, Satu S; Mirza, Ghazala G; Mühleisen, Thomas W TW; Musk, Bill B; Parkin, Melissa M; Rallidis, Loukianos L; Saramies, Jouko J; Sennblad, Bengt B; Shah, Sonia S; Sigurðsson, Gunnar G; Silveira, Angela A; Steinbach, Gerald G; Thorand, Barbara B; Trakalo, Joseph J; Veglia, Fabrizio F; Wennauer, Roman R; Winckler, Wendy W; Zabaneh, Delilah D; Campbell, Harry H; van Duijn, Cornelia C; Uitterlinden, Andre G AG; Hofman, Albert A; Sijbrands, Eric E; Abecasis, Goncalo R GR; Owen, Katharine R KR; Zeggini, Eleftheria E; Trip, Mieke D MD; Forouhi, Nita G NG; Syvänen, Ann-Christine AC; Eriksson, Johan G JG; Peltonen, Leena L; Nöthen, Markus M MM; Balkau, Beverley B; Palmer, Colin N A CN; Lyssenko, Valeriya V; Tuomi, Tiinamaija T; Isomaa, Bo B; Hunter, David J DJ; Qi, Lu L; , ; , ; , ; , ; , ; Shuldiner, Alan R AR; Roden, Michael M; Barroso, Ines I; Wilsgaard, Tom T; Beilby, John J; Hovingh, Kees K; Price, Jackie F JF; Wilson, James F JF; Rauramaa, Rainer R; Lakka, Timo A TA; Lind, Lars L; Dedoussis, George G; Njølstad, Inger I; Pedersen, Nancy L NL; Khaw, Kay-Tee KT; Wareham, Nicholas J NJ; Keinanen-Kiukaanniemi, Sirkka M SM; Saaristo, Timo E TE; Korpi-Hyövälti, Eeva E; Saltevo, Juha J; Laakso, Markku M; Kuusisto, Johanna J; Metspalu, Andres A; Collins, Francis S FS; Mohlke, Karen L KL; Bergman, Richard N RN; Tuomilehto, Jaakko J; Boehm, Bernhard O BO; Gieger, Christian C; Hveem, Kristian K; Cauchi, Stephane S; Froguel, Philippe P; Baldassarre, Damiano D; Tremoli, Elena E; Humphries, Steve E SE; Saleheen, Danish D; Danesh, John J; Ingelsson, Erik E; Ripatti, Samuli S; Salomaa, Veikko V; Erbel, Raimund R; Jöckel, Karl-Heinz KH; Moebus, Susanne S; Peters, Annette A; Illig, Thomas T; de Faire, Ulf U; Hamsten, Anders A; Morris, Andrew D AD; Donnelly, Peter J PJ; Frayling, Timothy M TM; Hattersley, Andrew T AT; Boerwinkle, Eric E; Melander, Olle O; Kathiresan, Sekar S; Nilsson, Peter M PM; Deloukas, Panos P; Thorsteinsdottir, Unnur U; Groop, Leif C LC; Stefansson, Kari K; Hu, Frank F; Pankow, James S JS; Dupuis, Josée J; Meigs, James B JB; Altshuler, David D; Boehnke, Michael M; McCarthy, Mark I MI; ,