Publications:

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The Role of Pharmacogenetics in Personalizing the Antidepressant and Anxiolytic Therapy.

Genes

Radosavljevic, Milica M; Svob Strac, Dubravka D; Jancic, Jasna J; Samardzic, Janko J

Publication Date: 2023-05-16

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 37239455

Variant Present in the following documents:

• genes-14-01095.pdf

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Intracrine androgen biosynthesis and drug resistance.

Cancer Drug Resistance (Alhambra, Calif.)

Penning, Trevor M TM; Asangani, Irfan A IA; Sprenger, Cynthia C; Plymate, Stephen S

Publication Date: 2020

Variant appearance in text: UGT2B17: Asp85Tyr

PubMed Link: 35582223

Variant Present in the following documents:

• cdr-3-912.pdf

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Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Translational And Clinical Pharmacology

Kim, Byungwook B; Yoon, Deok Yong DY; Lee, SeungHwan S; Jang, In-Jin IJ; Yu, Kyung-Sang KS; Cho, Joo-Youn JY; Oh, Jaeseong J

Publication Date: 2021-09

Variant appearance in text: UGT2B17: 253G>T; D85Y

PubMed Link: 34621706

Variant Present in the following documents:

• tcp-29-135-s001.xls, sheet 1

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Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Saudi Journal Of Biological Sciences

Aboul-Soud, Mourad A M MAM; Alzahrani, Alhussain J AJ; Mahmoud, Amer A

Publication Date: 2021-01

Variant appearance in text: UGT2B17: D85Y; rs72551387

PubMed Link: 33424349

Variant Present in the following documents:

• mmc1.xlsx, sheet 1

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The Identification of Admixture Patterns Could Refine Pharmacogenetic Counseling: Analysis of a Population-Based Sample in Mexico.

Frontiers In Pharmacology

Martínez-Magaña, José Jaime JJ; Genis-Mendoza, Alma Delia AD; Villatoro Velázquez, Jorge Ameth JA; Camarena, Beatriz B; Martín Del Campo Sanchez, Raul R; Fleiz Bautista, Clara C; Bustos Gamiño, Marycarmen M; Reséndiz, Esbehidy E; Aguilar, Alejandro A; Medina-Mora, María Elena ME; Nicolini, Humberto H

Publication Date: 2020

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 32390825

Variant Present in the following documents:

• fphar-11-00324.pdf

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CYP2D6 Genotype Predicts Plasma Concentrations of Tamoxifen Metabolites in Ethiopian Breast Cancer Patients.

Cancers

Ahmed, Jemal Hussien JH; Makonnen, Eyasu E; Fotoohi, Alan A; Aseffa, Abraham A; Howe, Rawleigh R; Aklillu, Eleni E

Publication Date: 2019-09-12

Variant appearance in text: UGT2B17: 253G>T; D85Y

PubMed Link: 31547390

Variant Present in the following documents:

• cancers-11-01353.pdf

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Evolving neoantigen profiles in colorectal cancers with DNA repair defects.

Genome Medicine

Rospo, Giuseppe G; Lorenzato, Annalisa A; Amirouchene-Angelozzi, Nabil N; Magrì, Alessandro A; Cancelliere, Carlotta C; Corti, Giorgio G; Negrino, Carola C; Amodio, Vito V; Montone, Monica M; Bartolini, Alice A; Barault, Ludovic L; Novara, Luca L; Isella, Claudio C; Medico, Enzo E; Bertotti, Andrea A; Trusolino, Livio L; Germano, Giovanni G; Di Nicolantonio, Federica F; Bardelli, Alberto A

Publication Date: 2019-06-28

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 31253177

Variant Present in the following documents:

• 13073_2019_654_MOESM2_ESM.xlsx, sheet 21

View BVdb publication page

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Targeted next generation sequencing as a tool for precision medicine.

Bmc Medical Genomics

Gulilat, Markus M; Lamb, Tyler T; Teft, Wendy A WA; Wang, Jian J; Dron, Jacqueline S JS; Robinson, John F JF; Tirona, Rommel G RG; Hegele, Robert A RA; Kim, Richard B RB; Schwarz, Ute I UI

Publication Date: 2019-06-03

Variant appearance in text: UGT2B17: D85Y; rs72551387

PubMed Link: 31159795

Variant Present in the following documents:

• 12920_2019_527_MOESM1_ESM.xlsx, sheet 6

View BVdb publication page

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Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol.

The Journal Of Pharmacology And Experimental Therapeutics

Teitelbaum, Aaron M AM; McDonald, Matthew G MG; Kowalski, John P JP; Parkinson, Oliver T OT; Scian, Michele M; Whittington, Dale D; Roellecke, Katharina K; Hanenberg, Helmut H; Wiek, Constanze C; Rettie, Allan E AE

Publication Date: 2019-02

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 30409834

Variant Present in the following documents:

• Main text

View BVdb publication page

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TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw.

Nature Communications

Gomes, Carolina Cavalieri CC; Gayden, Tenzin T; Bajic, Andrea A; Harraz, Osama F OF; Pratt, Jonathan J; Nikbakht, Hamid H; Bareke, Eric E; Diniz, Marina Gonçalves MG; Castro, Wagner Henriques WH; St-Onge, Pascal P; Sinnett, Daniel D; Han, HyeRim H; Rivera, Barbara B; Mikael, Leonie G LG; De Jay, Nicolas N; Kleinman, Claudia L CL; Valera, Elvis Terci ET; Bassenden, Angelia V AV; Berghuis, Albert M AM; Majewski, Jacek J; Nelson, Mark T MT; Gomez, Ricardo Santiago RS; Jabado, Nada N

Publication Date: 2018-11-01

Variant appearance in text: UGT2B17: D85Y; rs72551387

PubMed Link: 30385747

Variant Present in the following documents:

• 41467_2018_6690_MOESM8_ESM.xlsx, sheet 1

View BVdb publication page

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Pharmacogenetics of ugt genes in North African populations.

The Pharmacogenomics Journal

Gaibar, M M; Novillo, A A; Romero-Lorca, A A; Esteban, M E ME; Fernández-Santander, A A

Publication Date: 2018-09

Variant appearance in text: UGT2B17: Asp85Tyr

PubMed Link: 30061569

Variant Present in the following documents:

• Main text
• 41397_2018_Article_34.pdf

View BVdb publication page

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Pregnancy-Induced Perturbation of Urinary Androgenic Steroid Disposition.

Journal Of The Endocrine Society

Gadot, Yifat Y; Thörngren, John-Olof JO; Eklund, Emma E; Ekström, Lena L; Rane, Anders A

Publication Date: 2018-07-01

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 29942924

Variant Present in the following documents:

• js.2018-00064.pdf

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Regulation of Hepatic UGT2B15 by Methylation in Adults of Asian Descent.

Pharmaceutics

Oeser, Steffen G SG; Bingham, Jon-Paul JP; Collier, Abby C AC

Publication Date: 2018-01-07

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 29316660

Variant Present in the following documents:

• Main text
• pharmaceutics-10-00006.pdf

View BVdb publication page

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Uridine diphosphate-glucuronosyltransferase 2B15 D85Y gene polymorphism is associated with lower prostate cancer risk: a systematic review and meta-analysis.

Oncotarget

Zhong, Xiao X; Feng, Jiayu J; Xiao, Ya Y; Wang, Pingxian P; Fan, Qiming Q; Wu, Ronghua R; Hu, Wengang W; Huang, Chibing C

Publication Date: 2017-08-08

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 28881775

Variant Present in the following documents:

• Main text
• oncotarget-08-52837.pdf

View BVdb publication page

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Benchmarking of Whole Exome Sequencing and Ad Hoc Designed Panels for Genetic Testing of Hereditary Cancer.

Scientific Reports

Feliubadaló, Lídia L; Tonda, Raúl R; Gausachs, Mireia M; Trotta, Jean-Rémi JR; Castellanos, Elisabeth E; López-Doriga, Adriana A; Teulé, Àlex À; Tornero, Eva E; Del Valle, Jesús J; Gel, Bernat B; Gut, Marta M; Pineda, Marta M; González, Sara S; Menéndez, Mireia M; Navarro, Matilde M; Capellá, Gabriel G; Gut, Ivo I; Serra, Eduard E; Brunet, Joan J; Beltran, Sergi S; Lázaro, Conxi C

Publication Date: 2017-01-04

Variant appearance in text: UGT2B17: 253G>T; Asp85Tyr

PubMed Link: 28050010

Variant Present in the following documents:

• srep37984-s2.xls, sheet 1

View BVdb publication page

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Characterization of ADME gene variation in 21 populations by exome sequencing.

Pharmacogenetics And Genomics

Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR

Publication Date: 2017-03

Variant appearance in text: UGT2B17: 253G>T; Asp85Tyr; rs72551387

PubMed Link: 27984508

Variant Present in the following documents:

• fpc-27-089-s005.xlsx, sheet 2

View BVdb publication page

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iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports

Wang, Meng M; Wei, Liping L

Publication Date: 2016-08-16

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 27527004

Variant Present in the following documents:

• srep31321-s3.xls, sheet 1

View BVdb publication page

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Whole-genome sequencing in multiplex families with psychoses reveals mutations in the SHANK2 and SMARCA1 genes segregating with illness.

Molecular Psychiatry

Homann, O R OR; Misura, K K; Lamas, E E; Sandrock, R W RW; Nelson, P P; McDonough, S I SI; DeLisi, L E LE

Publication Date: 2016-12

Variant appearance in text: UGT2B17: D85Y; rs72551387

PubMed Link: 27001614

Variant Present in the following documents:

• NIHMS753666-supplement-2.xlsx, sheet 10

View BVdb publication page

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Classical and Non-Classical Roles for Pre-Receptor Control of DHT Metabolism in Prostate Cancer Progression.

Hormones & Cancer

Zhang, Ailin A; Zhang, Jiawei J; Plymate, Stephen S; Mostaghel, Elahe A EA

Publication Date: 2016-04

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 26797685

Variant Present in the following documents:

• Main text

View BVdb publication page

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Impact of UGT2B17 gene deletion on the steroid profile of an athlete.

Physiological Reports

Martín-Escudero, Pilar P; Muñoz-Guerra, Jesús J; Del Prado, Nayade N; Galindo Canales, Mercedes M; Fuentes Ferrer, Manuel M; Vargas, Soledad S; Soldevilla, Ana B AB; Serrano-Garde, Ester E; Miguel-Tobal, Francisco F; Maestro de Las Casas, Marisa M; Fernandez-Pérez, Cristina C

Publication Date: 2015-12

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 26668303

Variant Present in the following documents:

• PHY2-3-e12645.pdf

View BVdb publication page

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Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients.

Plos One

Romero-Lorca, Alicia A; Novillo, Apolonia A; Gaibar, María M; Bandrés, Fernando F; Fernández-Santander, Ana A

Publication Date: 2015

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 26176234

Variant Present in the following documents:

• Main text

View BVdb publication page

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Testosterone level in men with type 2 diabetes mellitus and related metabolic effects: A review of current evidence.

Journal Of Diabetes Investigation

Cheung, Kitty Kit Ting KK; Luk, Andrea On Yan AO; So, Wing Yee WY; Ma, Ronald Ching Wan RC; Kong, Alice Pik Shan AP; Chow, Francis Chun Chung FC; Chan, Juliana Chung Ngor JC

Publication Date: 2015-03

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 25802717

Variant Present in the following documents:

• jdi0006-0112.pdf

View BVdb publication page

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The impact of genetics and hormonal contraceptives on the steroid profile in female athletes.

Frontiers In Endocrinology

Schulze, Jenny J JJ; Mullen, Jenny E JE; Berglund Lindgren, Emma E; Ericsson, Magnus M; Ekström, Lena L; Hirschberg, Angelica Lindén AL

Publication Date: 2014

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 24782830

Variant Present in the following documents:

• fendo-05-00050.pdf

View BVdb publication page

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Genetic variation in UGT genes modify the associations of NSAIDs with risk of colorectal cancer: colon cancer family registry.

Genes, Chromosomes & Cancer

Scherer, Dominique D; Koepl, Lisel M LM; Poole, Elizabeth M EM; Balavarca, Yesilda Y; Xiao, Liren L; Baron, John A JA; Hsu, Li L; Coghill, Anna E AE; Campbell, Peter T PT; Kleinstein, Sarah E SE; Figueiredo, Jane C JC; Lampe, Johanna W JW; Buck, Katharina K; Potter, John D JD; Kulmacz, Richard J RJ; Jenkins, Mark A MA; Hopper, John L JL; Win, Aung K AK; Newcomb, Polly A PA; Ulrich, Cornelia M CM; Makar, Karen W KW

Publication Date: 2014-07

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 24677636

Variant Present in the following documents:

• Main text

View BVdb publication page

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Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.

Bmc Cancer

Vidal, Adriana C AC; Tucker, Cocoa C; Schildkraut, Joellen M JM; Richardson, Ricardo M RM; McPhail, Megan M; Freedland, Stephen J SJ; Hoyo, Cathrine C; Grant, Delores J DJ

Publication Date: 2013-11-22

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 24267955

Variant Present in the following documents:

• Main text
• 1471-2407-13-556.pdf

View BVdb publication page

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Phase two steroid metabolism and its roles in breast and prostate cancer patients.

Frontiers In Endocrinology

McNamara, Keely M KM; Nakamura, Yasuhiro Y; Miki, Yasuhiro Y; Sasano, Hironobu H

Publication Date: 2013-09-04

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 24027559

Variant Present in the following documents:

• Main text

View BVdb publication page

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Implication of Human UGT2B7, 2B15, and 2B17 in 19-Norandrosterone Metabolism.

Frontiers In Endocrinology

Strahm, Emmanuel E; Sjöberg, Ulf U; Garle, Mats M; Rane, Anders A; Ekström, Lena L

Publication Date: 2013

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 23805127

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association of uridine diphosphate-glucuronosyltransferase 2B gene variants with serum glucuronide levels and prostate cancer risk.

Genetic Testing And Molecular Biomarkers

Grant, Delores J DJ; Hoyo, Cathrine C; Oliver, Shannon D SD; Gerber, Leah L; Shuler, Katie K; Calloway, Elizabeth E; Gaines, Alexis R AR; McPhail, Megan M; Livingston, Jonathan N JN; Richardson, Ricardo M RM; Schildkraut, Joellen M JM; Freedland, Stephen J SJ

Publication Date: 2013-01

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 23098242

Variant Present in the following documents:

• Main text

View BVdb publication page

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Red wine and component flavonoids inhibit UGT2B17 in vitro.

Nutrition Journal

Jenkinson, Carl C; Petroczi, Andrea A; Naughton, Declan P DP

Publication Date: 2012-09-07

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 22958586

Variant Present in the following documents:

• 1475-2891-11-67.pdf

View BVdb publication page

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UGT2B17 genetic polymorphisms dramatically affect the pharmacokinetics of MK-7246 in healthy subjects in a first-in-human study.

Clinical Pharmacology And Therapeutics

Wang, Y-H YH; Trucksis, M M; McElwee, J J JJ; Wong, P H PH; Maciolek, C C; Thompson, C D CD; Prueksaritanont, T T; Garrett, G C GC; Declercq, R R; Vets, E E; Willson, K J KJ; Smith, R C RC; Klappenbach, J A JA; Opiteck, G J GJ; Tsou, J A JA; Gibson, C C; Laethem, T T; Panorchan, P P; Iwamoto, M M; Shaw, P M PM; Wagner, J A JA; Harrelson, J C JC

Publication Date: 2012-07

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 22669291

Variant Present in the following documents:

• Main text
• clpt201220a.pdf

View BVdb publication page

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Androgens and doping tests: genetic variation and pit-falls.

British Journal Of Clinical Pharmacology

Rane, Anders A; Ekström, Lena L

Publication Date: 2012-07

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 22506612

Variant Present in the following documents:

• Main text

View BVdb publication page

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Lack of association between common UGT2B nonsynonymous single-nucleotide polymorphisms and breast cancer in populations of African ancestry.

International Journal Of Cancer

Sun, Chang C; Huo, Dezheng D; Nemesure, Barbara B; Hennis, Anselm A; Leske, M Cristina MC; Wu, Suh-Yuh SY; Niu, Qun Q; Olopade, Olufunmilayo I OI; Di Rienzo, Anna A

Publication Date: 2012-06-01

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 21780111

Variant Present in the following documents:

• Main text

View BVdb publication page

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Differential allelic expression of c.1568C > A at UGT2B15 is due to variation in a novel cis-regulatory element in the 3'UTR.

Gene

Sun, Chang C; Southard, Catherine C; Olopade, Olufunmilayo I OI; Di Rienzo, Anna A

Publication Date: 2011-07-15

Variant appearance in text: UGT2B17: 253G>T

PubMed Link: 21513781

Variant Present in the following documents:

• Main text

View BVdb publication page

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SNP discovery, expression and cis-regulatory variation in the UGT2B genes.

The Pharmacogenomics Journal

Sun, C C; Southard, C C; Huo, D D; Hernandez, R D RD; Witonsky, D B DB; Olopade, O I OI; Di Rienzo, A A

Publication Date: 2012-08

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 21358749

Variant Present in the following documents:

• Main text

View BVdb publication page

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Potentially harmful advantage to athletes: a putative connection between UGT2B17 gene deletion polymorphism and renal disorders with prolonged use of anabolic androgenic steroids.

Substance Abuse Treatment, Prevention, And Policy

Deshmukh, Nawed N; Petróczi, Andrea A; Barker, James J; Székely, Andrea D AD; Hussain, Iltaf I; Naughton, Declan P DP

Publication Date: 2010-04-29

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 20429943

Variant Present in the following documents:

• 1747-597X-5-7.pdf

View BVdb publication page

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Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology

Yong, Mellissa M; Schwartz, Stephen M SM; Atkinson, Charlotte C; Makar, Karen W KW; Thomas, Sushma S SS; Newton, Katherine M KM; Aiello Bowles, Erin J EJ; Holt, Victoria L VL; Leisenring, Wendy M WM; Lampe, Johanna W JW

Publication Date: 2010-02

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 20142249

Variant Present in the following documents:

• Main text

View BVdb publication page

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Evidence for oxazepam as an in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion.

British Journal Of Clinical Pharmacology

He, Xi X; Hesse, Leah M LM; Hazarika, Suwagmani S; Masse, Gina G; Harmatz, Jerold S JS; Greenblatt, David J DJ; Court, Michael H MH

Publication Date: 2009-11

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 19916996

Variant Present in the following documents:

• Main text

View BVdb publication page

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Allelic imbalance (AI) identifies novel tissue-specific cis-regulatory variation for human UGT2B15.

Human Mutation

Sun, Chang C; Southard, Catherine C; Witonsky, David B DB; Olopade, Olufunmilayo I OI; Di Rienzo, Anna A

Publication Date: 2010-01

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 19847790

Variant Present in the following documents:

• Main text

View BVdb publication page

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Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system.

Drug Metabolism Reviews

Court, Michael H MH

Publication Date: 2010-02

Variant appearance in text: UGT2B17: D85Y

PubMed Link: 19821798

Variant Present in the following documents:

• Main text

View BVdb publication page

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UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.

Breast Cancer Research : Bcr

Sparks, Rachel R; Ulrich, Cornelia M CM; Bigler, Jeannette J; Tworoger, Shelley S SS; Yasui, Yutaka Y; Rajan, Kumar B KB; Porter, Peggy P; Stanczyk, Frank Z FZ; Ballard-Barbash, Rachel R; Yuan, Xiaopu X; Lin, Ming Gang MG; McVarish, Lynda L; Aiello, Erin J EJ; McTiernan, Anne A

Publication Date: 2004

Variant appearance in text: UGT2B17: Asp85Tyr

PubMed Link: 15318931

Variant Present in the following documents:

• Main text
• bcr818.pdf

View BVdb publication page

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