UGT2B10 c.199G>A ;(p.D67N)

Variant ID: 4-69681936-G-A

NM_001075.4(UGT2B10):c.199G>A;(p.D67N)

This variant was identified in 16 publications

View GRCh38 version.




Publications:


Pharmacogenetics and Schizophrenia-Can Genomics Improve the Treatment with Second-Generation Antipsychotics?

Biomedicines
Płaza, Olga O; Gałecki, Piotr P; Orzechowska, Agata A; Gałecka, Małgorzata M; Sobolewska-Nowak, Justyna J; Szulc, Agata A
Publication Date: 2022-12-07

Variant appearance in text: rs61750900
PubMed Link: 36551925
Variant Present in the following documents:
  • biomedicines-10-03165.pdf
View BVdb publication page



A potential implication of UDP-glucuronosyltransferase 2B10 in the detoxification of drugs used in pediatric hematopoietic stem cell transplantation setting: an in silico investigation.

Bmc Molecular And Cell Biology
Robin, Shannon S; Hassine, Khalil Ben KB; Muthukumaran, Jayaraman J; Jurkovic Mlakar, Simona S; Krajinovic, Maja M; Nava, Tiago T; Uppugunduri, Chakradhara Rao S CRS; Ansari, Marc M
Publication Date: 2022-01-21

Variant appearance in text: rs61750900
PubMed Link: 35062878
Variant Present in the following documents:
  • Main text
  • 12860_2021_Article_402.pdf
View BVdb publication page



A potential implication of UDP-glucuronosyltransferase 2B10 in the detoxification of drugs used in pediatric hematopoietic stem cell transplantation setting: an in silico investigation.

Bmc Molecular And Cell Biology
Robin, Shannon S; Hassine, Khalil Ben KB; Muthukumaran, Jayaraman J; Jurkovic Mlakar, Simona S; Krajinovic, Maja M; Nava, Tiago T; Uppugunduri, Chakradhara Rao S CRS; Ansari, Marc M
Publication Date: 2022-01-21

Variant appearance in text: rs61750900
PubMed Link: 35062878
Variant Present in the following documents:
  • Main text
  • 12860_2021_Article_402.pdf
View BVdb publication page



Genetic Polymorphisms Associated With the Pharmacokinetics, Pharmacodynamics and Adverse Effects of Olanzapine, Aripiprazole and Risperidone.

Frontiers In Pharmacology
Soria-Chacartegui, Paula P; Villapalos-García, Gonzalo G; Zubiaur, Pablo P; Abad-Santos, Francisco F; Koller, Dora D
Publication Date: 2021

Variant appearance in text: rs61750900
PubMed Link: 34335273
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenomic landscape of COVID-19 therapies from Indian population genomes.

Pharmacogenomics
Sahana, S S; Sivadas, Ambily A; Mangla, Mohit M; Jain, Abhinav A; Bhoyar, Rahul C RC; Pandhare, Kavita K; Mishra, Anushree A; Sharma, Disha D; Imran, Mohamed M; Senthivel, Vigneshwar V; Divakar, Mohit Kumar MK; Rophina, Mercy M; Jolly, Bani B; Batra, Arushi A; Sharma, Sumit S; Siwach, Sanjay S; Jadhao, Arun G AG; Palande, Nikhil V NV; Jha, Ganga Nath GN; Ashrafi, Nishat N; Mishra, Prashant Kumar PK; Vidhya, A K AK; Jain, Suman S; Dash, Debasis D; Kumar, Nachimuthu Senthil NS; Vanlallawma, Andrew A; Sarma, Ranjan Jyoti RJ; Chhakchhuak, Lalchhandama L; Kalyanaraman, Shantaraman S; Mahadevan, Radha R; Kandasamy, Sunitha S; Devi, Pabitha P; Rajagopal, Raskin Erusan RE; Ramya, J Ezhil JE; Devi, P Nirmala PN; Bajaj, Anjali A; Gupta, Vishu V; Mathew, Samatha S; Goswami, Sangam S; Prakash, Savinitha S; Joshi, Kandarp K; Kumla, Meya M; Sreedevi, S S; Gajjar, Devarshi D; Soraisham, Ronibala R; Yadav, Rohit R; Devi, Yumnam Silla YS; Gupta, Aayush A; Mukerji, Mitali M; Ramalingam, Sivaprakash S; Binukumar, B K BK; Sivasubbu, Sridhar S; Scaria, Vinod V
Publication Date: 2021-07

Variant appearance in text: rs61750900
PubMed Link: 34142560
Variant Present in the following documents:
  • pgs-2021-0028.pdf
View BVdb publication page



Clozapine Metabolism is Associated With Absolute Neutrophil Count in Individuals With Treatment-Resistant Schizophrenia.

Frontiers In Pharmacology
Willcocks, Isabella R IR; Legge, Sophie E SE; Nalmpanti, Mariana M; Mazzeo, Lucy L; King, Adrian A; Jansen, John J; Helthuis, Marinka M; Owen, Michael J MJ; O'Donovan, Michael C MC; Walters, James T R JTR; Pardiñas, Antonio F AF
Publication Date: 2021

Variant appearance in text: rs61750900
PubMed Link: 33959025
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic Association of Olanzapine Treatment Response in Han Chinese Schizophrenia Patients.

Frontiers In Pharmacology
Zhou, Wei W; Xu, Yong Y; Lv, Qinyu Q; Sheng, Yong-Hui YH; Chen, Luan L; Li, Mo M; Shen, Lu L; Huai, Cong C; Yi, Zhenghui Z; Cui, Donghong D; Qin, Shengying S
Publication Date: 2019

Variant appearance in text: rs61750900
PubMed Link: 30886581
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Comparison of Direct and Indirect Analytical Approaches to Measuring Total Nicotine Equivalents in Urine.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Taghavi, Taraneh T; Novalen, Maria M; Lerman, Caryn C; George, Tony P TP; Tyndale, Rachel F RF
Publication Date: 2018-08

Variant appearance in text: rs61750900
PubMed Link: 29853480
Variant Present in the following documents:
  • Main text
View BVdb publication page



Effect of UGT2B10, UGT2B17, FMO3, and OCT2 genetic variation on nicotine and cotinine pharmacokinetics and smoking in African Americans.

Pharmacogenetics And Genomics
Taghavi, Taraneh T; St Helen, Gideon G; Benowitz, Neal L NL; Tyndale, Rachel F RF
Publication Date: 2017-04

Variant appearance in text: rs61750900
PubMed Link: 28178031
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association between Glucuronidation Genotypes and Urinary NNAL Metabolic Phenotypes in Smokers.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Chen, Gang G; Luo, Shaman S; Kozlovich, Shannon S; Lazarus, Philip P
Publication Date: 2016-07

Variant appearance in text: rs61750900
PubMed Link: 27197298
Variant Present in the following documents:
  • Main text
View BVdb publication page



Recurrent inactivating RASA2 mutations in melanoma.

Nature Genetics
Arafeh, Rand R; Qutob, Nouar N; Emmanuel, Rafi R; Keren-Paz, Alona A; Madore, Jason J; Elkahloun, Abdel A; Wilmott, James S JS; Gartner, Jared J JJ; Di Pizio, Antonella A; Winograd-Katz, Sabina S; Sindiri, Sivasish S; Rotkopf, Ron R; Dutton-Regester, Ken K; Johansson, Peter P; Pritchard, Antonia L AL; Waddell, Nicola N; Hill, Victoria K VK; Lin, Jimmy C JC; Hevroni, Yael Y; Rosenberg, Steven A SA; Khan, Javed J; Ben-Dor, Shifra S; Niv, Masha Y MY; Ulitsky, Igor I; Mann, Graham J GJ; Scolyer, Richard A RA; Hayward, Nicholas K NK; Samuels, Yardena Y
Publication Date: 2015-12

Variant appearance in text: UGT2B10: D67N
PubMed Link: 26502337
Variant Present in the following documents:
  • NIHMS65345-supplement-Supplementary_table_3.xlsx, sheet 1
View BVdb publication page



Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes.

Oncotarget
Keerthikumar, Shivakumar S; Gangoda, Lahiru L; Liem, Michael M; Fonseka, Pamali P; Atukorala, Ishara I; Ozcitti, Cemil C; Mechler, Adam A; Adda, Christopher G CG; Ang, Ching-Seng CS; Mathivanan, Suresh S
Publication Date: 2015-06-20

Variant appearance in text: rs61750900
PubMed Link: 25944692
Variant Present in the following documents:
  • oncotarget-06-15375-s005.xlsx, sheet 2
View BVdb publication page



UGT1A and UGT2B genetic variation alters nicotine and nitrosamine glucuronidation in european and african american smokers.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Wassenaar, Catherine A CA; Conti, David V DV; Das, Soma S; Chen, Peixian P; Cook, Edwin H EH; Ratain, Mark J MJ; Benowitz, Neal L NL; Tyndale, Rachel F RF
Publication Date: 2015-01

Variant appearance in text: rs61750900
PubMed Link: 25277794
Variant Present in the following documents:
  • Main text
View BVdb publication page



A highly recurrent RPS27 5'UTR mutation in melanoma.

Oncotarget
Dutton-Regester, Ken K; Gartner, Jared J JJ; Emmanuel, Rafi R; Qutob, Nouar N; Davies, Michael A MA; Gershenwald, Jeffrey E JE; Robinson, William W; Robinson, Steven S; Rosenberg, Steven A SA; Scolyer, Richard A RA; Mann, Graham J GJ; Thompson, John F JF; Hayward, Nicholas K NK; Samuels, Yardena Y
Publication Date: 2014-05-30

Variant appearance in text: UGT2B10: D67N
PubMed Link: 24913145
Variant Present in the following documents:
  • oncotarget-05-2912-s003.xlsx, sheet 1
View BVdb publication page



The effect of UGT1A and UGT2B polymorphisms on colorectal cancer risk: haplotype associations and gene–environment interactions.

Genes, Chromosomes & Cancer
Angstadt, Andrea Y AY; Hartman, Terryl J TJ; Lesko, Samuel M SM; Muscat, Joshua E JE; Zhu, Junjia J; Gallagher, Carla J CJ; Lazarus, Philip P
Publication Date: 2014-06

Variant appearance in text: rs61750900
PubMed Link: 24822274
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenomics knowledge for personalized medicine.

Clinical Pharmacology And Therapeutics
Whirl-Carrillo, M M; McDonagh, E M EM; Hebert, J M JM; Gong, L L; Sangkuhl, K K; Thorn, C F CF; Altman, R B RB; Klein, T E TE
Publication Date: 2012-10

Variant appearance in text: rs61750900
PubMed Link: 22992668
Variant Present in the following documents:
  • Main text
View BVdb publication page



Glucuronidation genotypes and nicotine metabolic phenotypes: importance of functional UGT2B10 and UGT2B17 polymorphisms.

Cancer Research
Chen, Gang G; Giambrone, Nino E NE; Dluzen, Douglas F DF; Muscat, Joshua E JE; Berg, Arthur A; Gallagher, Carla J CJ; Lazarus, Philip P
Publication Date: 2010-10-01

Variant appearance in text: rs61750900
PubMed Link: 20876810
Variant Present in the following documents:
  • Main text
View BVdb publication page