Publications:

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A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Jang, H Josh HJ; Hostetter, Galen G; MacFarlane, Alexander W AW; Madaj, Zachary Z; Ross, Eric A EA; Hinoue, Toshinori T; Kulchycki, Justin R JR; Burgos, Ryan S RS; Tafseer, Mahvish M; Alpaugh, R Katherine RK; Schwebel, Candice L CL; Kokate, Rutika R; Geynisman, Daniel M DM; Zibelman, Matthew R MR; Ghatalia, Pooja P; Nichols, Peter W PW; Chung, Woonbok W; Madzo, Jozef J; Hahn, Noah M NM; Quinn, David I DI; Issa, Jean-Pierre J JJ; Topper, Michael J MJ; Baylin, Stephen B SB; Shen, Hui H; Campbell, Kerry S KS; Jones, Peter A PA; Plimack, Elizabeth R ER

Publication Date: 2023-03-16

Variant appearance in text: UGT2B7: T245T

PubMed Link: 36928921

Variant Present in the following documents:

• ccr-22-3642_supplementary_tables_1_suppts1.xlsx, sheet 3

View BVdb publication page

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Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.

Scientific Reports

Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA

Publication Date: 2022-10-14

Variant appearance in text: UGT2B7: T245T

PubMed Link: 36241656

Variant Present in the following documents:

• 41598_2022_20939_MOESM6_ESM.xlsx, sheet 2
• 41598_2022_20939_MOESM14_ESM.xlsx, sheet 2
• 41598_2022_20939_MOESM15_ESM.xlsx, sheet 2

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Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.

Frontiers In Pharmacology

Silgado-Guzmán, Daniel Felipe DF; Angulo-Aguado, Mariana M; Morel, Adrien A; Niño-Orrego, María José MJ; Ruiz-Torres, Daniel-Armando DA; Contreras Bravo, Nora Constanza NC; Restrepo, Carlos Martin CM; Ortega-Recalde, Oscar O; Fonseca-Mendoza, Dora Janeth DJ

Publication Date: 2022

Variant appearance in text: rs28365062

PubMed Link: 35846994

Variant Present in the following documents:

• Table1.xlsx, sheet 1
• fphar-13-931531.pdf

View BVdb publication page

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Effect of CYP4F2 Polymorphisms on Ticagrelor Pharmacokinetics in Healthy Chinese Volunteers.

Frontiers In Pharmacology

Nie, Shanshan S; Chen, Kaifeng K; Guo, Chengxian C; Pei, Qi Q; Zou, Chan C; Yao, Liangyuan L; Yuan, Hongbo H; Zhao, Xia X; Xie, Ran R; He, Xu X; Huang, Jie J; Yang, Guoping G

Publication Date: 2021

Variant appearance in text: rs28365062

PubMed Link: 35280252

Variant Present in the following documents:

• Main text
• fphar-12-797278.pdf

View BVdb publication page

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Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Translational And Clinical Pharmacology

Kim, Byungwook B; Yoon, Deok Yong DY; Lee, SeungHwan S; Jang, In-Jin IJ; Yu, Kyung-Sang KS; Cho, Joo-Youn JY; Oh, Jaeseong J

Publication Date: 2021-09

Variant appearance in text: N/A

PubMed Link: 34621706

Variant Present in the following documents:

View BVdb publication page

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Influence of SULT1A1*2 Polymorphism on Plasma Efavirenz Concentration in Thai HIV-1 Patients.

Pharmacogenomics And Personalized Medicine

Chamnanphon, Monpat M; Sukprasong, Rattanaporn R; Gaedigk, Andrea A; Manosuthi, Weerawat W; Chariyavilaskul, Pajaree P; Wittayalertpanya, Supeecha S; Koomdee, Napatrupron N; Jantararoungtong, Thawinee T; Puangpetch, Apichaya A; Sukasem, Chonlaphat C

Publication Date: 2021

Variant appearance in text: UGT2B7: 735A>G; rs28365062

PubMed Link: 34335044

Variant Present in the following documents:

• Main text
• pgpm-14-915.pdf

View BVdb publication page

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Case Report: A Variant Non-ketotic Hyperglycinemia With GLRX5 Mutations: Manifestation of Deficiency of Activities of the Respiratory Chain Enzymes.

Frontiers In Genetics

Feng, Wei-Xing WX; Zhuo, Xiu-Wei XW; Liu, Zhi-Mei ZM; Li, Jiu-Wei JW; Zhang, Wei-Hua WH; Wu, Yun Y; Han, Tong-Li TL; Fang, Fang F

Publication Date: 2021

Variant appearance in text: N/A

PubMed Link: 34054912

Variant Present in the following documents:

View BVdb publication page

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Novel germline TRAF3IP3 mutation in a dyad with familial acute B lymphoblastic leukemia.

Cancer Reports (Hoboken, N.J.)

Pommert, Lauren L; Burns, Robert R; Furumo, Quinlan Q; Pulakanti, Kirthi K; Brandt, Jon J; Burke, Michael J MJ; Rao, Sridhar S

Publication Date: 2021-06

Variant appearance in text: UGT2B7: 735A>G; T245T

PubMed Link: 33503336

Variant Present in the following documents:

• CNR2-4-e1335-s003.xlsx, sheet 1

View BVdb publication page

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Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Saudi Journal Of Biological Sciences

Aboul-Soud, Mourad A M MAM; Alzahrani, Alhussain J AJ; Mahmoud, Amer A

Publication Date: 2021-01

Variant appearance in text: N/A

PubMed Link: 33424349

Variant Present in the following documents:

View BVdb publication page

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Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells.

Npj Systems Biology And Applications

Immanuel, Selva Rupa Christinal SRC; Ghanate, Avinash D AD; Parmar, Dharmeshkumar S DS; Yadav, Ritu R; Uthup, Riya R; Panchagnula, Venkateswarlu V; Raghunathan, Anu A

Publication Date: 2021-01-08

Variant appearance in text: N/A

PubMed Link: 33420045

Variant Present in the following documents:

View BVdb publication page

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Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine.

British Journal Of Clinical Pharmacology

Yip, Vincent L M VLM; Pertinez, Henry H; Meng, Xiaoli X; Maggs, James L JL; Carr, Daniel F DF; Park, B Kevin BK; Marson, Anthony G AG; Pirmohamed, Munir M

Publication Date: 2021-06

Variant appearance in text: rs28365062

PubMed Link: 33217013

Variant Present in the following documents:

• Main text
• BCP-87-2572.pdf

View BVdb publication page

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Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing.

Clinical Pharmacokinetics

Yin, Anyue A; Ettaieb, Madeleine H T MHT; Swen, Jesse J JJ; van Deun, Liselotte L; Kerkhofs, Thomas M A TMA; van der Straaten, Robert J H M RJHM; Corssmit, Eleonora P M EPM; Gelderblom, Hans H; Kerstens, Michiel N MN; Feelders, Richard A RA; Eekhoff, Marelise M; Timmers, Henri J L M HJLM; D'Avolio, Antonio A; Cusato, Jessica J; Guchelaar, Henk-Jan HJ; Haak, Harm R HR; Moes, Dirk Jan A R DJAR

Publication Date: 2021-01

Variant appearance in text: N/A

PubMed Link: 32607875

Variant Present in the following documents:

View BVdb publication page

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Brazilian cohort and genes encoding for drug-metabolizing enzymes and drug transporters.

Pharmacogenomics

Kim, Vera V; Wal, Thijs van der TV; Nishi, Miriam Yumie MY; Montenegro, Luciana Ribeiro LR; Carrilho, Flair Jose FJ; Hoshida, Yujin Y; Ono, Suzane Kioko SK

Publication Date: 2020-06

Variant appearance in text: rs28365062

PubMed Link: 32486903

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association between ESR1, ESR2, HER2, UGT1A4, and UGT2B7 polymorphisms and breast Cancer in Jordan: a case-control study.

Bmc Cancer

Al-Eitan, Laith N LN; Rababa'h, Doaa M DM; Alghamdi, Mansour A MA; Khasawneh, Rame H RH

Publication Date: 2019-12-30

Variant appearance in text: rs28365062

PubMed Link: 31888550

Variant Present in the following documents:

• Main text
• 12885_2019_Article_6490.pdf

View BVdb publication page

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A pan-cancer analysis of synonymous mutations.

Nature Communications

Sharma, Yogita Y; Miladi, Milad M; Dukare, Sandeep S; Boulay, Karine K; Caudron-Herger, Maiwen M; Groß, Matthias M; Backofen, Rolf R; Diederichs, Sven S

Publication Date: 2019-06-12

Variant appearance in text: UGT2B7: 735A>G

PubMed Link: 31189880

Variant Present in the following documents:

• 41467_2019_10489_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Targeted next generation sequencing as a tool for precision medicine.

Bmc Medical Genomics

Gulilat, Markus M; Lamb, Tyler T; Teft, Wendy A WA; Wang, Jian J; Dron, Jacqueline S JS; Robinson, John F JF; Tirona, Rommel G RG; Hegele, Robert A RA; Kim, Richard B RB; Schwarz, Ute I UI

Publication Date: 2019-06-03

Variant appearance in text: N/A

PubMed Link: 31159795

Variant Present in the following documents:

View BVdb publication page

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Multiple genetic mutations caused by NKX6.3 depletion contribute to gastric tumorigenesis.

Scientific Reports

Yoon, Jung Hwan JH; Kim, Olga O; Eun, Jung Woo JW; Choi, Sung Sook SS; Ashktorab, Hassan H; Smoot, Duane T DT; Nam, Suk Woo SW; Park, Won Sang WS

Publication Date: 2018-12-04

Variant appearance in text: rs28365062

PubMed Link: 30514953

Variant Present in the following documents:

• 41598_2018_35733_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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South-south collaboration on HIV/AIDS prevention and treatment research: when birds of a feather rarely flock together.

Globalization And Health

Fonseca, Bruna de Paula Fonseca E BPFE; Albuquerque, Priscila Costa PC; Noyons, Ed E; Zicker, Fabio F

Publication Date: 2018-03-01

Variant appearance in text: rs28365062

PubMed Link: 29490665

Variant Present in the following documents:

• 12992_2018_341_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples.

Oncotarget

Ma, Shiyong S; Menon, Ranjeeta R; Poulos, Rebecca C RC; Wong, Jason W H JWH

Publication Date: 2017-11-10

Variant appearance in text: N/A

PubMed Link: 29221171

Variant Present in the following documents:

View BVdb publication page

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Identification and validation of the microRNA response elements in the 3'-untranslated region of the UDP glucuronosyltransferase (UGT) 2B7 and 2B15 genes by a functional genomics approach.

Biochemical Pharmacology

Papageorgiou, Ioannis I; Court, Michael H MH

Publication Date: 2017-12-15

Variant appearance in text: UGT2B7: 735A>G; rs28365062

PubMed Link: 28962835

Variant Present in the following documents:

• Main text

View BVdb publication page

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Characterization of ADME gene variation in 21 populations by exome sequencing.

Pharmacogenetics And Genomics

Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR

Publication Date: 2017-03

Variant appearance in text: N/A

PubMed Link: 27984508

Variant Present in the following documents:

View BVdb publication page

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Pharmacogenetics of efavirenz discontinuation for reported central nervous system symptoms appears to differ by race.

Pharmacogenetics And Genomics

Leger, Paul P; Chirwa, Sanika S; Turner, Megan M; Richardson, Danielle M DM; Baker, Paxton P; Leonard, Michael M; Erdem, Husamettin H; Olson, Lana L; Haas, David W DW

Publication Date: 2016-10

Variant appearance in text: rs28365062

PubMed Link: 27509478

Variant Present in the following documents:

• Main text

View BVdb publication page

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The Affymetrix DMET Plus platform reveals unique distribution of ADME-related variants in ethnic Arabs.

Disease Markers

Wakil, Salma M SM; Nguyen, Cao C; Muiya, Nzioka P NP; Andres, Editha E; Lykowska-Tarnowska, Agnieszka A; Baz, Batoul B; Tahir, Asma I AI; Meyer, Brian F BF; Morahan, Grant G; Dzimiri, Nduna N

Publication Date: 2015

Variant appearance in text: rs28365062

PubMed Link: 25802476

Variant Present in the following documents:

• 542543.f1.xlsx, sheet 1

View BVdb publication page

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Perspectives on pharmacogenomics of antiretroviral medications and HIV-associated comorbidities.

Current Opinion In Hiv And Aids

Haas, David W DW; Tarr, Philip E PE

Publication Date: 2015-03

Variant appearance in text: rs28365062

PubMed Link: 25565175

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pharmacogenomics of antimicrobial agents.

Pharmacogenomics

Aung, Ar Kar AK; Haas, David W DW; Hulgan, Todd T; Phillips, Elizabeth J EJ

Publication Date: 2014

Variant appearance in text: rs28365062

PubMed Link: 25495412

Variant Present in the following documents:

• Main text

View BVdb publication page

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Exploring the distribution of genetic markers of pharmacogenomics relevance in Brazilian and Mexican populations.

Plos One

Bonifaz-Peña, Vania V; Contreras, Alejandra V AV; Struchiner, Claudio Jose CJ; Roela, Rosimeire A RA; Furuya-Mazzotti, Tatiane K TK; Chammas, Roger R; Rangel-Escareño, Claudia C; Uribe-Figueroa, Laura L; Gómez-Vázquez, María José MJ; McLeod, Howard L HL; Hidalgo-Miranda, Alfredo A; Parra, Esteban J EJ; Fernández-López, Juan Carlos JC; Suarez-Kurtz, Guilherme G

Publication Date: 2014

Variant appearance in text: rs28365062

PubMed Link: 25419701

Variant Present in the following documents:

• Main text
• pone.0112640.pdf

View BVdb publication page

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Whole-genome sequencing of the world's oldest people.

Plos One

Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK

Publication Date: 2014

Variant appearance in text: N/A

PubMed Link: 25390934

Variant Present in the following documents:

View BVdb publication page

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The RPTEC/TERT1 cell line models key renal cell responses to the environmental toxicants, benzo[a]pyrene and cadmium.

Toxicology Reports

Simon, B R BR; Wilson, M J MJ; Wickliffe, J K JK

Publication Date: 2014

Variant appearance in text: rs28365062

PubMed Link: 25126521

Variant Present in the following documents:

• mmc1.xls, sheet 1

View BVdb publication page

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Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations in HIV-infected adults with CYP2B6 slow metabolizer genotypes.

The Journal Of Antimicrobial Chemotherapy

Haas, David W DW; Kwara, Awewura A; Richardson, Danielle M DM; Baker, Paxton P; Papageorgiou, Ioannis I; Acosta, Edward P EP; Morse, Gene D GD; Court, Michael H MH

Publication Date: 2014-08

Variant appearance in text: rs28365062

PubMed Link: 24729586

Variant Present in the following documents:

• Main text

View BVdb publication page

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Effect of a poly(ADP-ribose) polymerase-1 inhibitor against esophageal squamous cell carcinoma cell lines.

Cancer Science

Nasuno, Tomomitsu T; Mimaki, Sachiyo S; Okamoto, Makito M; Esumi, Hiroyasu H; Tsuchihara, Katsuya K

Publication Date: 2014-02

Variant appearance in text: N/A

PubMed Link: 24219164

Variant Present in the following documents:

View BVdb publication page

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PharmGKB summary: zidovudine pathway.

Pharmacogenetics And Genomics

Ghodke, Yogita Y; Anderson, Peter L PL; Sangkuhl, Katrin K; Lamba, Jatinder J; Altman, Russ B RB; Klein, Teri E TE

Publication Date: 2012-12

Variant appearance in text: rs28365062

PubMed Link: 22960662

Variant Present in the following documents:

• Main text

View BVdb publication page

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Worldwide variation in human drug-metabolism enzyme genes CYP2B6 and UGT2B7: implications for HIV/AIDS treatment.

Pharmacogenomics

Li, Jing J; Menard, Vincent V; Benish, Rebekah L RL; Jurevic, Richard J RJ; Guillemette, Chantal C; Stoneking, Mark M; Zimmerman, Peter A PA; Mehlotra, Rajeev K RK

Publication Date: 2012-04

Variant appearance in text: N/A

PubMed Link: 22462748

Variant Present in the following documents:

View BVdb publication page

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Modest but variable effect of rifampin on steady-state plasma pharmacokinetics of efavirenz in healthy African-American and Caucasian volunteers.

Antimicrobial Agents And Chemotherapy

Kwara, Awewura A; Tashima, Karen T KT; Dumond, Julie B JB; Poethke, Pamela P; Kurpewski, Jaclyn J; Kashuba, Angela D M AD; Court, Michael H MH; Greenblatt, David J DJ

Publication Date: 2011-07

Variant appearance in text: rs28365062

PubMed Link: 21518840

Variant Present in the following documents:

• Main text

View BVdb publication page

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Diabetes mellitus reduces activity of human UDP-glucuronosyltransferase 2B7 in liver and kidney leading to decreased formation of mycophenolic acid acyl-glucuronide metabolite.

Drug Metabolism And Disposition: The Biological Fate Of Chemicals

Dostalek, Miroslav M; Court, Michael H MH; Hazarika, Suwagmani S; Akhlaghi, Fatemeh F

Publication Date: 2011-03

Variant appearance in text: UGT2B7: 735A>G; rs28365062

PubMed Link: 21123165

Variant Present in the following documents:

• Main text

View BVdb publication page

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Zidovudine and Lamivudine for HIV Infection.

Clinical Medicine Reviews In Therapeutics

Anderson, Peter L PL; Rower, Joseph E JE

Publication Date: 2010

Variant appearance in text: UGT2B7: 735A>G

PubMed Link: 20953318

Variant Present in the following documents:

• Main text

View BVdb publication page

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Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system.

Drug Metabolism Reviews

Court, Michael H MH

Publication Date: 2010-02

Variant appearance in text: UGT2B7: 735A>G

PubMed Link: 19821798

Variant Present in the following documents:

• Main text

View BVdb publication page

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CYP2B6, CYP2A6 and UGT2B7 genetic polymorphisms are predictors of efavirenz mid-dose concentration in HIV-infected patients.

Aids (London, England)

Kwara, Awewura A; Lartey, Margaret M; Sagoe, Kwamena W C KW; Kenu, Ernest E; Court, Michael H MH

Publication Date: 2009-10-23

Variant appearance in text: UGT2B7: 735A>G; rs28365062

PubMed Link: 19779319

Variant Present in the following documents:

• Main text

View BVdb publication page

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Interindividual variability in pharmacokinetics of generic nucleoside reverse transcriptase inhibitors in TB/HIV-coinfected Ghanaian patients: UGT2B7*1c is associated with faster zidovudine clearance and glucuronidation.

Journal Of Clinical Pharmacology

Kwara, Awewura A; Lartey, Margaret M; Boamah, Isaac I; Rezk, Naser L NL; Oliver-Commey, Joseph J; Kenu, Ernest E; Kashuba, Angela D M AD; Court, Michael H MH

Publication Date: 2009-09

Variant appearance in text: UGT2B7: 735A>G; rs28365062

PubMed Link: 19628728

Variant Present in the following documents:

• Main text

View BVdb publication page

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Single nucleotide polymorphism discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 gene.

Pharmacogenetics And Genomics

Innocenti, Federico F; Liu, Wanqing W; Fackenthal, Donna D; Ramírez, Jacqueline J; Chen, Peixian P; Ye, Xin X; Wu, Xiaolin X; Zhang, Wei W; Mirkov, Snezana S; Das, Soma S; Cook, Edwin E; Ratain, Mark J MJ

Publication Date: 2008-08

Variant appearance in text: UGT2B7: T245T; rs28365062

PubMed Link: 18622261

Variant Present in the following documents:

• Main text

View BVdb publication page

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