Evolving spike-protein N -glycosylation in SARS-CoV-2 variants.
Biorxiv : The Preprint Server For Biology
Baboo, Sabyasachi S; Diedrich, Jolene K JK; Torres, Jonathan L JL; Copps, Jeffrey J; Singh, Bhavya B; Garrett, Patrick T PT; Ward, Andrew B AB; Paulson, James C JC; Yates, John R JR
Rickettsia felis DNA recovered from a child who lived in southern Africa 2000 years ago.
Communications Biology
Rifkin, Riaan F RF; Vikram, Surendra S; Alcorta, Jaime J; Ramond, Jean-Baptiste JB; Cowan, Don A DA; Jakobsson, Mattias M; Schlebusch, Carina M CM; Lombard, Marlize M
Whole-genome sequencing of SARS-CoV-2 isolates from symptomatic and asymptomatic individuals in Tanzania.
Frontiers In Medicine
Mziray, Shabani Ramadhani SR; van Zwetselaar, Marco M; Kayuki, Charles C CC; Mbelele, Peter M PM; Makubi, Abel N AN; Magesa, Alex S AS; Kisonga, Riziki M RM; Sonda, Tolbert B TB; Kibiki, Gibson S GS; Githinji, George G; Heysell, Scott K SK; Chilongola, Jaffu O JO; Mpagama, Stellah G SG
Genetic and Structural Analysis of SARS-CoV-2 Spike Protein for Universal Epitope Selection.
Molecular Biology And Evolution
Markosian, Christopher C; Staquicini, Daniela I DI; Dogra, Prashant P; Dodero-Rojas, Esteban E; Lubin, Joseph H JH; Tang, Fenny H F FHF; Smith, Tracey L TL; Contessoto, Vinícius G VG; Libutti, Steven K SK; Wang, Zhihui Z; Cristini, Vittorio V; Khare, Sagar D SD; Whitford, Paul C PC; Burley, Stephen K SK; Onuchic, José N JN; Pasqualini, Renata R; Arap, Wadih W
Neutralisation Hierarchy of SARS-CoV-2 Variants of Concern Using Standardised, Quantitative Neutralisation Assays Reveals a Correlation With Disease Severity; Towards Deciphering Protective Antibody Thresholds.
Frontiers In Immunology
Cantoni, Diego D; Mayora-Neto, Martin M; Nadesalingam, Angalee A; Wells, David A DA; Carnell, George W GW; Ohlendorf, Luis L; Ferrari, Matteo M; Palmer, Phil P; Chan, Andrew C Y ACY; Smith, Peter P; Bentley, Emma M EM; Einhauser, Sebastian S; Wagner, Ralf R; Page, Mark M; Raddi, Gianmarco G; Baxendale, Helen H; Castillo-Olivares, Javier J; Heeney, Jonathan J; Temperton, Nigel N
SARS-CoV-2 Delta Variant Displays Moderate Resistance to Neutralizing Antibodies and Spike Protein Properties of Higher Soluble ACE2 Sensitivity, Enhanced Cleavage and Fusogenic Activity.
Viruses
Neerukonda, Sabari Nath SN; Vassell, Russell R; Lusvarghi, Sabrina S; Wang, Richard R; Echegaray, Fernando F; Bentley, Lisa L; Eakin, Ann E AE; Erlandson, Karl J KJ; Katzelnick, Leah C LC; Weiss, Carol D CD; Wang, Wei W
Development of an efficient Sanger sequencing-based assay for detecting SARS-CoV-2 spike mutations.
Plos One
Lim, Ho Jae HJ; Park, Min Young MY; Jung, Hye Soo HS; Kwon, Youngjin Y; Kim, Inhee I; Kim, Dong Kwan DK; Yu, Nae N; Sung, Nackmoon N; Lee, Sun-Hwa SH; Park, Jung Eun JE; Yang, Yong-Jin YJ
A Next-Generation Vaccine Candidate Using Alternative Epitopes to Protect against Wuhan and All Significant Mutant Variants of SARS-CoV-2: An Immunoinformatics Approach.
Aging And Disease
Bhattacharya, Manojit M; Sharma, Ashish Ranjan AR; Ghosh, Pratik P; Lee, Sang-Soo SS; Chakraborty, Chiranjib C
Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2.
Science Advances
Rodrigues, Kristen A KA; Rodriguez-Aponte, Sergio A SA; Dalvie, Neil C NC; Lee, Jeong Hyun JH; Abraham, Wuhbet W; Carnathan, Diane G DG; Jimenez, Luis E LE; Ngo, Julia T JT; Chang, Jason Y H JYH; Zhang, Zeli Z; Yu, Jingyou J; Chang, Aiquan A; Nakao, Catherine C; Goodwin, Benjamin B; Naranjo, Christopher A CA; Zhang, Libin L; Silva, Murillo M; Barouch, Dan H DH; Silvestri, Guido G; Crotty, Shane S; Love, J Christopher JC; Irvine, Darrell J DJ
Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2.
Science Advances
Rodrigues, Kristen A KA; Rodriguez-Aponte, Sergio A SA; Dalvie, Neil C NC; Lee, Jeong Hyun JH; Abraham, Wuhbet W; Carnathan, Diane G DG; Jimenez, Luis E LE; Ngo, Julia T JT; Chang, Jason Y H JYH; Zhang, Zeli Z; Yu, Jingyou J; Chang, Aiquan A; Nakao, Catherine C; Goodwin, Benjamin B; Naranjo, Christopher A CA; Zhang, Libin L; Silva, Murillo M; Barouch, Dan H DH; Silvestri, Guido G; Crotty, Shane S; Love, J Christopher JC; Irvine, Darrell J DJ
A glycan gate controls opening of the SARS-CoV-2 spike protein.
Nature Chemistry
Sztain, Terra T; Ahn, Surl-Hee SH; Bogetti, Anthony T AT; Casalino, Lorenzo L; Goldsmith, Jory A JA; Seitz, Evan E; McCool, Ryan S RS; Kearns, Fiona L FL; Acosta-Reyes, Francisco F; Maji, Suvrajit S; Mashayekhi, Ghoncheh G; McCammon, J Andrew JA; Ourmazd, Abbas A; Frank, Joachim J; McLellan, Jason S JS; Chong, Lillian T LT; Amaro, Rommie E RE
An N-Cadherin 2 expressing epithelial cell subpopulation predicts response to surgery, chemotherapy and immunotherapy in bladder cancer.
Nature Communications
Gouin, Kenneth H KH; Ing, Nathan N; Plummer, Jasmine T JT; Rosser, Charles J CJ; Ben Cheikh, Bassem B; Oh, Catherine C; Chen, Stephanie S SS; Chan, Keith Syson KS; Furuya, Hideki H; Tourtellotte, Warren G WG; Knott, Simon R V SRV; Theodorescu, Dan D
Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike.
Cell
Tong, Pei P; Gautam, Avneesh A; Windsor, Ian W IW; Travers, Meghan M; Chen, Yuezhou Y; Garcia, Nicholas N; Whiteman, Noah B NB; McKay, Lindsay G A LGA; Storm, Nadia N; Malsick, Lauren E LE; Honko, Anna N AN; Lelis, Felipe J N FJN; Habibi, Shaghayegh S; Jenni, Simon S; Cai, Yongfei Y; Rennick, Linda J LJ; Duprex, W Paul WP; McCarthy, Kevin R KR; Lavine, Christy L CL; Zuo, Teng T; Lin, Junrui J; Zuiani, Adam A; Feldman, Jared J; MacDonald, Elizabeth A EA; Hauser, Blake M BM; Griffths, Anthony A; Seaman, Michael S MS; Schmidt, Aaron G AG; Chen, Bing B; Neuberg, Donna D; Bajic, Goran G; Harrison, Stephen C SC; Wesemann, Duane R DR
SARS-CoV-2 worldwide replication drives rapid rise and selection of mutations across the viral genome: a time-course study - potential challenge for vaccines and therapies.
Embo Molecular Medicine
Weber, Stefanie S; Ramirez, Christina M CM; Weiser, Barbara B; Burger, Harold H; Doerfler, Walter W
Rapid screening for SARS-CoV-2 variants of concern in clinical and environmental samples using nested RT-PCR assays targeting key mutations of the spike protein.
Water Research
La Rosa, G G; Mancini, P P; Bonanno Ferraro, G G; Veneri, C C; Iaconelli, M M; Lucentini, L L; Bonadonna, L L; Brusaferro, S S; Brandtner, D D; Fasanella, A A; Pace, L L; Parisi, A A; Galante, D D; Suffredini, E E
A public vaccine-induced human antibody protects against SARS-CoV-2 and emerging variants.
Biorxiv : The Preprint Server For Biology
Schmitz, Aaron J AJ; Turner, Jackson S JS; Liu, Zhuoming Z; Aziati, Ishmael D ID; Chen, Rita E RE; Joshi, Astha A; Bricker, Traci L TL; Darling, Tamarand L TL; Adelsberg, Daniel C DC; Alsoussi, Wafaa B WB; Case, James Brett JB; Lei, Tingting T; Thapa, Mahima M; Amanat, Fatima F; O'Halloran, Jane A JA; Shi, Pei-Yong PY; Presti, Rachel M RM; Krammer, Florian F; Bajic, Goran G; Whelan, Sean P J SPJ; Diamond, Michael S MS; Boon, Adrianus C M ACM; Ellebedy, Ali H AH
Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike.
Biorxiv : The Preprint Server For Biology
Tong, Pei P; Gautam, Avneesh A; Windsor, Ian I; Travers, Meghan M; Chen, Yuezhou Y; Garcia, Nicholas N; Whiteman, Noah B NB; McKay, Lindsay G A LGA; Lelis, Felipe J N FJN; Habibi, Shaghayegh S; Cai, Yongfei Y; Rennick, Linda J LJ; Duprex, W Paul WP; McCarthy, Kevin R KR; Lavine, Christy L CL; Zuo, Teng T; Lin, Junrui J; Zuiani, Adam A; Feldman, Jared J; MacDonald, Elizabeth A EA; Hauser, Blake M BM; Griffths, Anthony A; Seaman, Michael S MS; Schmidt, Aaron G AG; Chen, Bing B; Neuberg, Donna D; Bajic, Goran G; Harrison, Stephen C SC; Wesemann, Duane R DR
Design of a companion bioinformatic tool to detect the emergence and geographical distribution of SARS-CoV-2 Spike protein genetic variants.
Journal Of Translational Medicine
Massacci, Alice A; Sperandio, Eleonora E; D'Ambrosio, Lorenzo L; Maffei, Mariano M; Palombo, Fabio F; Aurisicchio, Luigi L; Ciliberto, Gennaro G; Pallocca, Matteo M
Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.
Nature Communications
Schütte, Moritz M; Risch, Thomas T; Abdavi-Azar, Nilofar N; Boehnke, Karsten K; Schumacher, Dirk D; Keil, Marlen M; Yildiriman, Reha R; Jandrasits, Christine C; Borodina, Tatiana T; Amstislavskiy, Vyacheslav V; Worth, Catherine L CL; Schweiger, Caroline C; Liebs, Sandra S; Lange, Martin M; Warnatz, Hans-Jörg HJ; Butcher, Lee M LM; Barrett, James E JE; Sultan, Marc M; Wierling, Christoph C; Golob-Schwarzl, Nicole N; Lax, Sigurd S; Uranitsch, Stefan S; Becker, Michael M; Welte, Yvonne Y; Regan, Joseph Lewis JL; Silvestrov, Maxine M; Kehler, Inge I; Fusi, Alberto A; Kessler, Thomas T; Herwig, Ralf R; Landegren, Ulf U; Wienke, Dirk D; Nilsson, Mats M; Velasco, Juan A JA; Garin-Chesa, Pilar P; Reinhard, Christoph C; Beck, Stephan S; Schäfer, Reinhold R; Regenbrecht, Christian R A CR; Henderson, David D; Lange, Bodo B; Haybaeck, Johannes J; Keilholz, Ulrich U; Hoffmann, Jens J; Lehrach, Hans H; Yaspo, Marie-Laure ML