GC c.194A>G ;(p.K65R)

Variant ID: 4-72634085-T-C

NM_000583.3(GC):c.194A>G;(p.K65R)

This variant was identified in 27 publications

View GRCh38 version.




Publications:


HaploCoV: unsupervised classification and rapid detection of novel emerging variants of SARS-CoV-2.

Communications Biology
Chiara, Matteo M; Horner, David S DS; Ferrandi, Erika E; Gissi, Carmela C; Pesole, Graziano G
Publication Date: 2023-04-22

Variant appearance in text: GC: 194A>G
PubMed Link: 37087497
Variant Present in the following documents:
  • 42003_2023_4784_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Relapse timing is associated with distinct evolutionary dynamics in DLBCL.

Medrxiv : The Preprint Server For Health Sciences
Hilton, Laura K LK; Ngu, Henry S HS; Collinge, Brett B; Dreval, Kostiantyn K; Ben-Neriah, Susana S; Rushton, Christopher K CK; Wong, Jasper C H JCH; Cruz, Manuela M; Roth, Andrew A; Boyle, Merrill M; Meissner, Barbara B; Slack, Graham W GW; Farinha, Pedro P; Craig, Jeffrey W JW; Gerrie, Alina S AS; Freeman, Ciara L CL; Villa, Diego D; Crump, Michael M; Shepherd, Lois L; Hay, Annette E AE; Kuruvilla, John J; Savage, Kerry J KJ; Kridel, Robert R; Karsan, Aly A; Marra, Marco A MA; Sehn, Laurie H LH; Steidl, Christian C; Morin, Ryan D RD; Scott, David W DW
Publication Date: 2023-03-08

Variant appearance in text: GC: K65R
PubMed Link: 36945587
Variant Present in the following documents:
  • media-1.xlsx, sheet 14
View BVdb publication page



Genomic evolution towards azole resistance in Candida glabrata clinical isolates unveils the importance of CgHxt4/6/7 in azole accumulation.

Communications Biology
Galocha, Mónica M; Viana, Romeu R; Pais, Pedro P; Silva-Dias, Ana A; Cavalheiro, Mafalda M; Miranda, Isabel M IM; Van Ende, Mieke M; Souza, Caio S CS; Costa, Catarina C; Branco, Joana J; Soares, Cláudio M CM; Van Dijck, Patrick P; Rodrigues, Acácio G AG; Teixeira, Miguel C MC
Publication Date: 2022-10-21

Variant appearance in text: GC: 194A>G
PubMed Link: 36271293
Variant Present in the following documents:
  • 42003_2022_4087_MOESM4_ESM.xlsx, sheet 6
  • 42003_2022_4087_MOESM4_ESM.xlsx, sheet 5
  • 42003_2022_4087_MOESM4_ESM.xlsx, sheet 3
  • 42003_2022_4087_MOESM4_ESM.xlsx, sheet 4
View BVdb publication page



Transmitted Drug Resistance in Antiretroviral Therapy-Naive Persons With Acute/Early/Primary HIV Infection: A Systematic Review and Meta-Analysis.

Frontiers In Pharmacology
Guo, Chunxiang C; Wu, Yaxin Y; Zhang, Yang Y; Liu, Xinchao X; Li, Aixin A; Gao, Meixia M; Zhang, Tong T; Wu, Hao H; Chen, Guanzhi G; Huang, Xiaojie X
Publication Date: 2021

Variant appearance in text: GC: K65R
PubMed Link: 34899288
Variant Present in the following documents:
  • Main text
  • fphar-12-718763.pdf
View BVdb publication page



PANDAA intentionally violates conventional qPCR design to enable durable, mismatch-agnostic detection of highly polymorphic pathogens.

Communications Biology
MacLeod, Iain J IJ; Rowley, Christopher F CF; Essex, M M
Publication Date: 2021-02-18

Variant appearance in text: GC: K65R
PubMed Link: 33603155
Variant Present in the following documents:
  • Main text
  • 42003_2021_Article_1751.pdf
View BVdb publication page



K-Ras-Activated Cells Can Develop into Lung Tumors When Runx3-Mediated Tumor Suppressor Pathways Are Abrogated.

Molecules And Cells
Lee, You-Soub YS; Lee, Ja-Yeol JY; Song, Soo-Hyun SH; Kim, Da-Mi DM; Lee, Jung-Won JW; Chi, Xin-Zi XZ; Ito, Yoshiaki Y; Bae, Suk-Chul SC
Publication Date: 2020-10-31

Variant appearance in text: GC: 194A>G; Lys65Arg
PubMed Link: 33115981
Variant Present in the following documents:
  • molce-43-889_Supple.xlsx, sheet 1
View BVdb publication page



Alteration of enzymes and their application to nucleic acid amplification (Review).

International Journal Of Molecular Medicine
Yasukawa, Kiyoshi K; Yanagihara, Itaru I; Fujiwara, Shinsuke S
Publication Date: 2020-11

Variant appearance in text: GC: K65R
PubMed Link: 33000189
Variant Present in the following documents:
  • Main text
  • ijmm-46-05-1633.pdf
View BVdb publication page



A nutrient-limited screen unmasks rifabutin hyperactivity for extensively drug-resistant Acinetobacter baumannii.

Nature Microbiology
Luna, Brian B; Trebosc, Vincent V; Lee, Bosul B; Bakowski, Malina M; Ulhaq, Amber A; Yan, Jun J; Lu, Peggy P; Cheng, Jiaqi J; Nielsen, Travis T; Lim, Juhyeon J; Ketphan, Warisa W; Eoh, Hyungjin H; McNamara, Case C; Skandalis, Nicholas N; She, Rosemary R; Kemmer, Christian C; Lociuro, Sergio S; Dale, Glenn E GE; Spellberg, Brad B
Publication Date: 2020-09

Variant appearance in text: GC: 194A>G
PubMed Link: 32514072
Variant Present in the following documents:
  • NIHMS1592993-supplement-1592993_Supp_Tab2.xlsx, sheet 14
View BVdb publication page



Association of CMV genomic mutations with symptomatic infection and hearing loss in congenital CMV infection.

Bmc Infectious Diseases
Dobbins, G Clement GC; Patki, Amit A; Chen, Dongquan D; Tiwari, Hemant K HK; Hendrickson, Curtis C; Britt, William J WJ; Fowler, Karen K; Chen, Jake Y JY; Boppana, Suresh B SB; Ross, Shannon A SA
Publication Date: 2019-12-10

Variant appearance in text: GC: K65R
PubMed Link: 31822287
Variant Present in the following documents:
  • 12879_2019_Article_4681.pdf
View BVdb publication page



Predictors of mortality within the first year of initiating antiretroviral therapy in urban and rural Kenya: A prospective cohort study.

Plos One
Silverman, Rachel A RA; John-Stewart, Grace C GC; Beck, Ingrid A IA; Milne, Ross R; Kiptinness, Catherine C; McGrath, Christine J CJ; Richardson, Barbra A BA; Chohan, Bhavna B; Sakr, Samah R SR; Frenkel, Lisa M LM; Chung, Michael H MH
Publication Date: 2019

Variant appearance in text: GC: K65R
PubMed Link: 31584992
Variant Present in the following documents:
  • pone.0223411.pdf
View BVdb publication page



HIV-1 drug resistance testing is essential for heavily-treated patients switching from first- to second-line regimens in resource-limited settings: evidence from routine clinical practice in Cameroon.

Bmc Infectious Diseases
Takou, Desire D; Fokam, Joseph J; Teto, Georges G; Santoro, Maria-Mercedes MM; Ceccherini-Silberstein, Francesca F; Nanfack, Aubin Joseph AJ; Sosso, Samuel Martin SM; Dambaya, Béatrice B; Salpini, Romina R; Billong, Serge Clotaire SC; Gori, Caterina C; Fokunang, Charles Ntungwen CN; Cappelli, Giulia G; Colizzi, Vittorio V; Perno, Carlo-Federico CF; Ndjolo, Alexis A
Publication Date: 2019-03-12

Variant appearance in text: GC: K65R
PubMed Link: 30871487
Variant Present in the following documents:
  • Main text
  • 12879_2019_Article_3871.pdf
View BVdb publication page



Template-primer binding affinity and RNase H cleavage specificity contribute to the strand transfer efficiency of HIV-1 reverse transcriptase.

The Journal Of Biological Chemistry
Luczkowiak, Joanna J; Matamoros, Tania T; Menéndez-Arias, Luis L
Publication Date: 2018-08-31

Variant appearance in text: GC: K65R
PubMed Link: 29991591
Variant Present in the following documents:
  • Main text
View BVdb publication page



Virological response and resistance among HIV-infected children receiving long-term antiretroviral therapy without virological monitoring in Uganda and Zimbabwe: Observational analyses within the randomised ARROW trial.

Plos Medicine
Szubert, Alexander J AJ; Prendergast, Andrew J AJ; Spyer, Moira J MJ; Musiime, Victor V; Musoke, Philippa P; Bwakura-Dangarembizi, Mutsa M; Nahirya-Ntege, Patricia P; Thomason, Margaret J MJ; Ndashimye, Emmanuel E; Nkanya, Immaculate I; Senfuma, Oscar O; Mudenge, Boniface B; Klein, Nigel N; Gibb, Diana M DM; Walker, A Sarah AS; ,
Publication Date: 2017-11

Variant appearance in text: GC: K65R
PubMed Link: 29136032
Variant Present in the following documents:
  • Main text
  • pmed.1002432.pdf
View BVdb publication page



Validation of participant eligibility for pre-exposure prophylaxis: Baseline data from the PRELUDE demonstration project.

Plos One
Vaccher, Stefanie J SJ; Grulich, Andrew E AE; Haire, Bridget G BG; Conway, Damian P DP; Poynten, Isobel M IM; Ooi, Catriona C; Foster, Rosalind R; Templeton, David J DJ; Zablotska, Iryna B IB; ,
Publication Date: 2017

Variant appearance in text: GC: K65R
PubMed Link: 28950022
Variant Present in the following documents:
  • pone.0185398.s002.pdf
View BVdb publication page



Variant discovery in the sheep milk transcriptome using RNA sequencing.

Bmc Genomics
Suárez-Vega, Aroa A; Gutiérrez-Gil, Beatriz B; Klopp, Christophe C; Tosser-Klopp, Gwenola G; Arranz, Juan José JJ
Publication Date: 2017-02-15

Variant appearance in text: GC: 194A>G
PubMed Link: 28202015
Variant Present in the following documents:
  • 12864_2017_3581_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Once vs twice-daily abacavir and lamivudine in African children.

Aids (London, England)
Musiime, Victor V; Kasirye, Philip P; Naidoo-James, Bethany B; Nahirya-Ntege, Patricia P; Mhute, Tawanda T; Cook, Adrian A; Mugarura, Lincoln L; Munjoma, Marshall M; Thoofer, Navdeep K NK; Ndashimye, Emmanuel E; Nankya, Immaculate I; Spyer, Moira J MJ; Thomason, Margaret J MJ; Snowden, Wendy W; Gibb, Diana M DM; Walker, Ann Sarah AS; ,
Publication Date: 2016-07-17

Variant appearance in text: GC: K65R
PubMed Link: 27064996
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mutations Related to Antiretroviral Resistance Identified by Ultra-Deep Sequencing in HIV-1 Infected Children under Structured Interruptions of HAART.

Plos One
Vazquez-Guillen, Jose Manuel JM; Palacios-Saucedo, Gerardo C GC; Rivera-Morales, Lydia G LG; Garcia-Campos, Jorge J; Ortiz-Lopez, Rocio R; Noguera-Julian, Marc M; Paredes, Roger R; Vielma-Ramirez, Herlinda J HJ; Ramirez, Teresa J TJ; Chavez-Garcia, Marcelino M; Lopez-Guillen, Paulo P; Briones-Lara, Evangelina E; Sanchez-Sanchez, Luz M LM; Vazquez-Martinez, Carlos A CA; Rodriguez-Padilla, Cristina C
Publication Date: 2016

Variant appearance in text: GC: K65R
PubMed Link: 26807922
Variant Present in the following documents:
  • pone.0147591.pdf
View BVdb publication page



Cross-clade simultaneous HIV drug resistance genotyping for reverse transcriptase, protease, and integrase inhibitor mutations by Illumina MiSeq.

Retrovirology
Dudley, Dawn M DM; Bailey, Adam L AL; Mehta, Shruti H SH; Hughes, Austin L AL; Kirk, Gregory D GD; Westergaard, Ryan P RP; O'Connor, David H DH
Publication Date: 2014-12-23

Variant appearance in text: GC: K65R
PubMed Link: 25533166
Variant Present in the following documents:
  • Main text
View BVdb publication page



HIV type 1 drug resistance patterns among patients failing first and second line antiretroviral therapy in Nairobi, Kenya.

Bmc Research Notes
Koigi, Peter P; Ngayo, Musa Otieno MO; Khamadi, Samoel S; Ngugi, Caroline C; Nyamache, Anthony Kebira AK
Publication Date: 2014-12-09

Variant appearance in text: GC: K65R
PubMed Link: 25487529
Variant Present in the following documents:
  • 13104_2014_Article_3405.pdf
View BVdb publication page



Development and customization of a color-coded microbeads-based assay for drug resistance in HIV-1 reverse transcriptase.

Plos One
Gu, Lijun L; Kawana-Tachikawa, Ai A; Shiino, Teiichiro T; Nakamura, Hitomi H; Koga, Michiko M; Kikuchi, Tadashi T; Adachi, Eisuke E; Koibuchi, Tomohiko T; Ishida, Takaomi T; Gao, George F GF; Matsushita, Masaki M; Sugiura, Wataru W; Iwamoto, Aikichi A; Hosoya, Noriaki N
Publication Date: 2014

Variant appearance in text: GC: K65R
PubMed Link: 25314293
Variant Present in the following documents:
  • Main text
  • pone.0109823.pdf
View BVdb publication page



Incidence and risk factors for first line anti retroviral treatment failure among Ugandan children attending an urban HIV clinic.

Aids Research And Therapy
Sebunya, Robert R; Musiime, Victor V; Kitaka, Sabrina Bakeera SB; Ndeezi, Grace G
Publication Date: 2013-11-11

Variant appearance in text: GC: K65R
PubMed Link: 24215971
Variant Present in the following documents:
  • 1742-6405-10-25.pdf
View BVdb publication page



Simultaneous detection of major drug resistance mutations in the protease and reverse transcriptase genes for HIV-1 subtype C by use of a multiplex allele-specific assay.

Journal Of Clinical Microbiology
Zhang, Guoqing G; Cai, Fangping F; Zhou, Zhiyong Z; DeVos, Joshua J; Wagar, Nick N; Diallo, Karidia K; Zulu, Isaac I; Wadonda-Kabondo, Nellie N; Stringer, Jeffrey S A JS; Weidle, Paul J PJ; Ndongmo, Clement B CB; Sikazwe, Izukanji I; Sarr, Abdoulaye A; Kagoli, Matthew M; Nkengasong, John J; Gao, Feng F; Yang, Chunfu C
Publication Date: 2013-11

Variant appearance in text: GC: K65R
PubMed Link: 23985909
Variant Present in the following documents:
  • Main text
View BVdb publication page



Human APOBEC3G-mediated hypermutation is associated with antiretroviral therapy failure in HIV-1 subtype C-infected individuals.

Journal Of The International Aids Society
Neogi, Ujjwal U; Shet, Anita A; Sahoo, Pravat Nalini PN; Bontell, Irene I; Ekstrand, Maria L ML; Banerjea, Akhil C AC; Sonnerborg, Anders A
Publication Date: 2013-02-25

Variant appearance in text: GC: K65R
PubMed Link: 23443042
Variant Present in the following documents:
  • Main text
  • JIAS-16-18472.pdf
View BVdb publication page



Development of Buffalo Hump in the course of antiretroviral therapy including raltegravir and unboosted atazanavir: a case report and review of the literature.

Journal Of Medical Case Reports
Ceccarelli, Giancarlo G; d'Ettorre, Gabriella G; Marchetti, Francesco F; Rizza, Cecilia C; Mastroianni, Claudio M CM; Carlesimo, Bruno B; Vullo, Vincenzo V
Publication Date: 2011-02-17

Variant appearance in text: GC: K65R
PubMed Link: 21329500
Variant Present in the following documents:
  • Main text
  • 1752-1947-5-70.pdf
View BVdb publication page



Nucleoside and nucleotide analogs select in culture for different patterns of drug resistance in human immunodeficiency virus types 1 and 2.

Antimicrobial Agents And Chemotherapy
Ntemgwa, Michel L ML; Toni, Thomas d'Aquin Td; Brenner, Bluma G BG; Oliveira, Maureen M; Asahchop, Eugene L EL; Moisi, Daniela D; Wainberg, Mark A MA
Publication Date: 2009-02

Variant appearance in text: GC: K65R
PubMed Link: 19064892
Variant Present in the following documents:
  • Main text
View BVdb publication page



Comparison of G-to-A mutation frequencies induced by APOBEC3 proteins in H9 cells and peripheral blood mononuclear cells in the context of impaired processivities of drug-resistant human immunodeficiency virus type 1 reverse transcriptase variants.

Journal Of Virology
Knoepfel, Stefanie Andrea SA; Salisch, Nadine Christina NC; Huelsmann, Peter Michael PM; Rauch, Pia P; Walter, Hauke H; Metzner, Karin Jutta KJ
Publication Date: 2008-07

Variant appearance in text: GC: K65R
PubMed Link: 18448538
Variant Present in the following documents:
  • Main text
View BVdb publication page



High genetic variability of HIV-1 in female sex workers from Argentina.

Retrovirology
Pando, María A MA; Eyzaguirre, Lindsay M LM; Carrion, Gladys G; Montano, Silvia M SM; Sanchez, José L JL; Carr, Jean K JK; Avila, María M MM
Publication Date: 2007-08-13

Variant appearance in text: GC: K65R
PubMed Link: 17697319
Variant Present in the following documents:
  • Main text
  • 1742-4690-4-58.pdf
View BVdb publication page