Constructing a polygenic risk score for childhood obesity using functional data analysis.
Econometrics And Statistics
Craig, Sarah J C SJC; Kenney, Ana M AM; Lin, Junli J; Paul, Ian M IM; Birch, Leann L LL; Savage, Jennifer S JS; Marini, Michele E ME; Chiaromonte, Francesca F; Reimherr, Matthew L ML; Makova, Kateryna D KD
Genetic Interactions with Intrauterine Diabetes Exposure in Relation to Obesity: The EPOCH and Project Viva Studies.
Pediatric Reports
Stanislawski, Maggie A MA; Litkowski, Elizabeth E; Fore, Ruby R; Rifas-Shiman, Sheryl L SL; Oken, Emily E; Hivert, Marie-France MF; Lange, Ethan M EM; Lange, Leslie A LA; Dabelea, Dana D; Raghavan, Sridharan S
Genetic risk of obesity as a modifier of associations between neighbourhood environment and body mass index: an observational study of 335 046 UK Biobank participants.
Bmj Nutrition, Prevention & Health
Mason, Kate E KE; Palla, Luigi L; Pearce, Neil N; Phelan, Jody J; Cummins, Steven S
The Role of Inflammatory Cytokines as Intermediates in the Pathway from Increased Adiposity to Disease.
Obesity (Silver Spring, Md.)
Kalaoja, Marita M; Corbin, Laura J LJ; Tan, Vanessa Y VY; Ahola-Olli, Ari V AV; Havulinna, Aki S AS; Santalahti, Kristiina K; Pitkänen, Niina N; Lehtimäki, Terho T; Lyytikäinen, Leo-Pekka LP; Raitoharju, Emma E; Seppälä, Ilkka I; Kähönen, Mika M; Ripatti, Samuli S; Palotie, Aarno A; Perola, Markus M; Viikari, Jorma S JS; Jalkanen, Sirpa S; Maksimow, Mikael M; Salomaa, Veikko V; Salmi, Marko M; Raitakari, Olli T OT; Kettunen, Johannes J; Timpson, Nicholas J NJ
Body mass index and all cause mortality in HUNT and UK Biobank studies: linear and non-linear mendelian randomisation analyses.
Bmj (Clinical Research Ed.)
Sun, Yi-Qian YQ; Burgess, Stephen S; Staley, James R JR; Wood, Angela M AM; Bell, Steven S; Kaptoge, Stephen K SK; Guo, Qi Q; Bolton, Thomas R TR; Mason, Amy M AM; Butterworth, Adam S AS; Di Angelantonio, Emanuele E; Vie, Gunnhild Å GÅ; Bjørngaard, Johan H JH; Kinge, Jonas Minet JM; Chen, Yue Y; Mai, Xiao-Mei XM
Assessing the causal role of body mass index on cardiovascular health in young adults: Mendelian randomization and recall-by-genotype analyses.
Circulation
Wade, Kaitlin H KH; Chiesa, Scott T ST; Hughes, Alun D AD; Chaturvedi, Nish N; Charakida, Marietta M; Rapala, Alicja A; Muthurangu, Vivek V; Khan, Tauseef T; Finer, Nicholas N; Sattar, Naveed N; Howe, Laura D LD; Fraser, Abigail A; Lawlor, Debbie A DA; Davey Smith, George G; Deanfield, John E JE; Timpson, Nicholas J NJ
Evaluation of the causal effects between subjective wellbeing and cardiometabolic health: mendelian randomisation study.
Bmj (Clinical Research Ed.)
Wootton, Robyn E RE; Lawn, Rebecca B RB; Millard, Louise A C LAC; Davies, Neil M NM; Taylor, Amy E AE; Munafò, Marcus R MR; Timpson, Nicholas J NJ; Davis, Oliver S P OSP; Davey Smith, George G; Haworth, Claire M A CMA
A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses.
Plos Genetics
Baranski, Thomas J TJ; Kraja, Aldi T AT; Fink, Jill L JL; Feitosa, Mary M; Lenzini, Petra A PA; Borecki, Ingrid B IB; Liu, Ching-Ti CT; Cupples, L Adrienne LA; North, Kari E KE; Province, Michael A MA
Association of Body Mass Index With Cardiometabolic Disease in the UK Biobank: A Mendelian Randomization Study.
Jama Cardiology
Lyall, Donald M DM; Celis-Morales, Carlos C; Ward, Joey J; Iliodromiti, Stamatina S; Anderson, Jana J JJ; Gill, Jason M R JMR; Smith, Daniel J DJ; Ntuk, Uduakobong Efanga UE; Mackay, Daniel F DF; Holmes, Michael V MV; Sattar, Naveed N; Pell, Jill P JP
Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study.
Plos Medicine
Noyce, Alastair J AJ; Kia, Demis A DA; Hemani, Gibran G; Nicolas, Aude A; Price, T Ryan TR; De Pablo-Fernandez, Eduardo E; Haycock, Philip C PC; Lewis, Patrick A PA; Foltynie, Thomas T; Davey Smith, George G; , ; Schrag, Anette A; Lees, Andrew J AJ; Hardy, John J; Singleton, Andrew A; Nalls, Mike A MA; Pearce, Neil N; Lawlor, Debbie A DA; Wood, Nicholas W NW
Relationship between salivary/pancreatic amylase and body mass index: a systems biology approach.
Bmc Medicine
Bonnefond, Amélie A; Yengo, Loïc L; Dechaume, Aurélie A; Canouil, Mickaël M; Castelain, Maxime M; Roger, Estelle E; Allegaert, Frédéric F; Caiazzo, Robert R; Raverdy, Violeta V; Pigeyre, Marie M; Arredouani, Abdelilah A; Borys, Jean-Michel JM; Lévy-Marchal, Claire C; Weill, Jacques J; Roussel, Ronan R; Balkau, Beverley B; Marre, Michel M; Pattou, François F; Brousseau, Thierry T; Froguel, Philippe P
Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity.
Molecular Metabolism
Keller, Maria M; Hopp, Lydia L; Liu, Xuanshi X; Wohland, Tobias T; Rohde, Kerstin K; Cancello, Raffaella R; Klös, Matthias M; Bacos, Karl K; Kern, Matthias M; Eichelmann, Fabian F; Dietrich, Arne A; Schön, Michael R MR; Gärtner, Daniel D; Lohmann, Tobias T; Dreßler, Miriam M; Stumvoll, Michael M; Kovacs, Peter P; DiBlasio, Anna-Maria AM; Ling, Charlotte C; Binder, Hans H; Blüher, Matthias M; Böttcher, Yvonne Y
Gene-obesogenic environment interactions in the UK Biobank study.
International Journal Of Epidemiology
Tyrrell, Jessica J; Wood, Andrew R AR; Ames, Ryan M RM; Yaghootkar, Hanieh H; Beaumont, Robin N RN; Jones, Samuel E SE; Tuke, Marcus A MA; Ruth, Katherine S KS; Freathy, Rachel M RM; Davey Smith, George G; Joost, Stéphane S; Guessous, Idris I; Murray, Anna A; Strachan, David P DP; Kutalik, Zoltán Z; Weedon, Michael N MN; Frayling, Timothy M TM
Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci.
Plos Genetics
Jones, Samuel E SE; Tyrrell, Jessica J; Wood, Andrew R AR; Beaumont, Robin N RN; Ruth, Katherine S KS; Tuke, Marcus A MA; Yaghootkar, Hanieh H; Hu, Youna Y; Teder-Laving, Maris M; Hayward, Caroline C; Roenneberg, Till T; Wilson, James F JF; Del Greco, Fabiola F; Hicks, Andrew A AA; Shin, Chol C; Yun, Chang-Ho CH; Lee, Seung Ku SK; Metspalu, Andres A; Byrne, Enda M EM; Gehrman, Philip R PR; Tiemeier, Henning H; Allebrandt, Karla V KV; Freathy, Rachel M RM; Murray, Anna A; Hinds, David A DA; Frayling, Timothy M TM; Weedon, Michael N MN
Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease.
Diabetes
Yaghootkar, Hanieh H; Lotta, Luca A LA; Tyrrell, Jessica J; Smit, Roelof A J RA; Jones, Sam E SE; Donnelly, Louise L; Beaumont, Robin R; Campbell, Archie A; Tuke, Marcus A MA; Hayward, Caroline C; Ruth, Katherine S KS; Padmanabhan, Sandosh S; Jukema, J Wouter JW; Palmer, Colin C CC; Hattersley, Andrew A; Freathy, Rachel M RM; Langenberg, Claudia C; Wareham, Nicholas J NJ; Wood, Andrew R AR; Murray, Anna A; Weedon, Michael N MN; Sattar, Naveed N; Pearson, Ewan E; Scott, Robert A RA; Frayling, Timothy M TM
Height, body mass index, and socioeconomic status: mendelian randomisation study in UK Biobank.
Bmj (Clinical Research Ed.)
Tyrrell, Jessica J; Jones, Samuel E SE; Beaumont, Robin R; Astley, Christina M CM; Lovell, Rebecca R; Yaghootkar, Hanieh H; Tuke, Marcus M; Ruth, Katherine S KS; Freathy, Rachel M RM; Hirschhorn, Joel N JN; Wood, Andrew R AR; Murray, Anna A; Weedon, Michael N MN; Frayling, Timothy M TM
Genetic studies of body mass index yield new insights for obesity biology.
Nature
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