Publications:

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Impact of Hyper- and Hypo-Uricemia on Kidney Function.

Biomedicines

Miake, Junichiro J; Hisatome, Ichiro I; Tomita, Katsuyuki K; Isoyama, Tadahiro T; Sugihara, Shinobu S; Kuwabara, Masanari M; Ogino, Kazuhide K; Ninomiya, Haruaki H

Publication Date: 2023-04-24

Variant appearance in text: ABCG2: Q126X

PubMed Link: 37238929

Variant Present in the following documents:

• Main text
• biomedicines-11-01258.pdf

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Cannabis Pharmacogenomics: A Path to Personalized Medicine.

Current Issues In Molecular Biology

Babayeva, Mariana M; Loewy, Zvi G ZG

Publication Date: 2023-04-17

Variant appearance in text: ABCG2: Q126X; rs72552713

PubMed Link: 37185752

Variant Present in the following documents:

• Main text
• cimb-45-00228.pdf

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ABCG2 in Acute Myeloid Leukemia: Old and New Perspectives.

International Journal Of Molecular Sciences

Damiani, Daniela D; Tiribelli, Mario M

Publication Date: 2023-04-12

Variant appearance in text: ABCG2: Q126X

PubMed Link: 37108308

Variant Present in the following documents:

• Main text
• ijms-24-07147.pdf

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Evaluation of ABCG2-mediated extra-renal urate excretion in hemodialysis patients.

Scientific Reports

Ohashi, Yuki Y; Toyoda, Masao M; Saito, Nobumichi N; Koizumi, Masahiro M; Kanai, Genta G; Komaba, Hirotaka H; Kimura, Moritsugu M; Wada, Takehiko T; Takahashi, Hiroo H; Takahashi, Yuichiro Y; Ishida, Naoto N; Kakuta, Takatoshi T; Fukagawa, Masafumi M; Ichida, Kimiyoshi K

Publication Date: 2023-01-13

Variant appearance in text: ABCG2: Q126X; rs72552713

PubMed Link: 36639673

Variant Present in the following documents:

• Main text
• 41598_2022_Article_26519.pdf
• 41598_2022_26519_MOESM1_ESM.pdf

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Gene Dose-Dependent and Additive Effects of ABCG2 rs2231142 and SLC2A9 rs3733591 Genetic Polymorphisms on Serum Uric Acid Levels.

Metabolites

Park, Jin-Woo JW; Noh, Ji-Hyeon JH; Kim, Jong-Min JM; Lee, Hwa-Young HY; Kim, Kyoung-Ah KA; Park, Ji-Young JY

Publication Date: 2022-11-29

Variant appearance in text: rs72552713

PubMed Link: 36557230

Variant Present in the following documents:

• Main text
• metabolites-12-01192.pdf

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Comparison of genetic susceptibility to lung adenocarcinoma and squamous cell carcinoma in Japanese patients using a novel panel for cancer-related drug-metabolizing enzyme genes.

Scientific Reports

Ohnami, Sumiko S; Naruoka, Akane A; Isaka, Mitsuhiro M; Mizuguchi, Maki M; Nakatani, Sou S; Kamada, Fukumi F; Shimoda, Yuji Y; Sakai, Ai A; Ohshima, Keiichi K; Hatakeyama, Keiichi K; Maruyama, Kouji K; Ohde, Yasuhisa Y; Kenmotsu, Hirotsugu H; Takahashi, Toshiaki T; Akiyama, Yasuto Y; Nagashima, Takeshi T; Urakami, Kenichi K; Ohnami, Shumpei S; Yamaguchi, Ken K

Publication Date: 2022-10-26

Variant appearance in text: rs72552713

PubMed Link: 36289279

Variant Present in the following documents:

• Main text
• 41598_2022_Article_22914.pdf

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Trends in the Contribution of Genetic Susceptibility Loci to Hyperuricemia and Gout and Associated Novel Mechanisms.

Frontiers In Cell And Developmental Biology

Zhao, Jianan J; Guo, Shicheng S; Schrodi, Steven J SJ; He, Dongyi D

Publication Date: 2022

Variant appearance in text: rs72552713

PubMed Link: 35813212

Variant Present in the following documents:

• Main text
• fcell-10-937855.pdf

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Examining an Association of Single Nucleotide Polymorphisms with Hyperuricemia in Chinese Flight Attendants.

Pharmacogenomics And Personalized Medicine

Ye, Jianpin J; Zeng, Zhiwei Z; Chen, Yuxian Y; Wu, Zhenkun Z; Yang, Qingwei Q; Sun, Tao T

Publication Date: 2022

Variant appearance in text: ABCG2: Q126X; rs72552713

PubMed Link: 35702613

Variant Present in the following documents:

• Main text
• pgpm-15-589.pdf

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Germline variants in cancer therapy.

Cancer Drug Resistance (Alhambra, Calif.)

Kaehler, Meike M; Cascorbi, Ingolf I

Publication Date: 2019

Variant appearance in text: rs72552713

PubMed Link: 35582146

Variant Present in the following documents:

• cdr-2-18.pdf

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Pharmacokinetics of Tenofovir Alafenamide Fumarate and Tenofovir in the Chinese People: Effects of Non-Genetic Factors and Genetic Variations.

Pharmacogenomics And Personalized Medicine

Li, Xue X; Tan, Xin-Yi XY; Cui, Xue-Jun XJ; Yang, Ming M; Chen, Chao C; Chen, Xiao-Yun XY

Publication Date: 2021

Variant appearance in text: rs72552713

PubMed Link: 34703277

Variant Present in the following documents:

• Main text
• pgpm-14-1315.pdf

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Genomic stability at the coding regions of the multidrug transporter gene ABCB1: insights into the development of alternative drug resistance mechanisms in human leukemia cells.

Cancer Drug Resistance (Alhambra, Calif.)

Chen, Kevin G KG; Duran, George E GE; Mogul, Mark J MJ; Wang, Yan C YC; Ross, Kevin L KL; Jaffrézou, Jean-Pierre JP; Huff, Lyn M LM; Johnson, Kory R KR; Fojo, Tito T; Lacayo, Norman J NJ; Sikic, Branimir I BI

Publication Date: 2020

Variant appearance in text: rs72552713

PubMed Link: 34541464

Variant Present in the following documents:

• cdr-3-959-SupplementaryMaterials.xlsx, sheet 5

View BVdb publication page

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Function of Uric Acid Transporters and Their Inhibitors in Hyperuricaemia.

Frontiers In Pharmacology

Sun, Hao-Lu HL; Wu, Yi-Wan YW; Bian, He-Ge HG; Yang, Hui H; Wang, Heng H; Meng, Xiao-Ming XM; Jin, Juan J

Publication Date: 2021

Variant appearance in text: ABCG2: Q126X

PubMed Link: 34335246

Variant Present in the following documents:

• Main text

View BVdb publication page

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Urate Transporters in the Kidney: What Clinicians Need to Know.

Electrolyte & Blood Pressure : E & Bp

Chung, Sungjin S; Kim, Gheun-Ho GH

Publication Date: 2021-06

Variant appearance in text: ABCG2: Q126X

PubMed Link: 34290818

Variant Present in the following documents:

• Main text
• ebp-19-1.pdf

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Circulating microRNA alternations in primary hyperuricemia and gout.

Arthritis Research & Therapy

Bohatá, Jana J; Horváthová, Veronika V; Pavlíková, Markéta M; Stibůrková, Blanka B

Publication Date: 2021-07-10

Variant appearance in text: ABCG2: Q126X; rs72552713

PubMed Link: 34246297

Variant Present in the following documents:

• Main text

View BVdb publication page

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The Role of ABCG2 in the Pathogenesis of Primary Hyperuricemia and Gout-An Update.

International Journal Of Molecular Sciences

Eckenstaler, Robert R; Benndorf, Ralf A RA

Publication Date: 2021-06-22

Variant appearance in text: ABCG2: 376C>T; Q126X; rs72552713

PubMed Link: 34206432

Variant Present in the following documents:

• Main text
• ijms-22-06678.pdf

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Estradiol regulates intestinal ABCG2 to promote urate excretion via the PI3K/Akt pathway.

Nutrition & Metabolism

Liu, Lei L; Zhao, Tianyi T; Shan, Lizhen L; Cao, Ling L; Zhu, Xiaoxia X; Xue, Yu Y

Publication Date: 2021-06-18

Variant appearance in text: ABCG2: Q126X

PubMed Link: 34144706

Variant Present in the following documents:

• Main text
• 12986_2021_Article_583.pdf

View BVdb publication page

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Porphyrin accumulation in humans with common dysfunctional variants of ABCG2, a porphyrin transporter: potential association with acquired photosensitivity.

Human Cell

Sakiyama, Masayuki M; Matsuo, Hirotaka H; Toyoda, Yu Y; Yonekura, Yuiko Y; Ishikawa, Takahiro T; Nakayama, Akiyoshi A; Higashino, Toshihide T; Kawamura, Yusuke Y; Fujimoto, Norihiro N; Shinomiya, Nariyoshi N; Satoh, Takahiro T

Publication Date: 2021-07

Variant appearance in text: ABCG2: Q126X; rs72552713

PubMed Link: 34009629

Variant Present in the following documents:

• Main text
• 13577_2021_Article_534.pdf

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Substantial anti-gout effect conferred by common and rare dysfunctional variants of URAT1/SLC22A12.

Rheumatology (Oxford, England)

Toyoda, Yu Y; Kawamura, Yusuke Y; Nakayama, Akiyoshi A; Nakaoka, Hirofumi H; Higashino, Toshihide T; Shimizu, Seiko S; Ooyama, Hiroshi H; Morimoto, Keito K; Uchida, Naohiro N; Shigesawa, Ryuichiro R; Takeuchi, Kenji K; Inoue, Ituro I; Ichida, Kimiyoshi K; Suzuki, Hiroshi H; Shinomiya, Nariyoshi N; Takada, Tappei T; Matsuo, Hirotaka H

Publication Date: 2021-11-03

Variant appearance in text: ABCG2: Q126X

PubMed Link: 33821957

Variant Present in the following documents:

• Main text

View BVdb publication page

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Medically Important Alterations in Transport Function and Trafficking of ABCG2.

International Journal Of Molecular Sciences

Homolya, László L

Publication Date: 2021-03-10

Variant appearance in text: ABCG2: Q126X; rs72552713

PubMed Link: 33801813

Variant Present in the following documents:

• Main text
• ijms-22-02786.pdf

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Identification of Two Dysfunctional Variants in the ABCG2 Urate Transporter Associated with Pediatric-Onset of Familial Hyperuricemia and Early-Onset Gout.

International Journal Of Molecular Sciences

Toyoda, Yu Y; Pavelcová, Kateřina K; Bohatá, Jana J; Ješina, Pavel P; Kubota, Yu Y; Suzuki, Hiroshi H; Takada, Tappei T; Stiburkova, Blanka B

Publication Date: 2021-02-16

Variant appearance in text: ABCG2: 376C>T; Q126X; rs72552713

PubMed Link: 33669292

Variant Present in the following documents:

• Main text

View BVdb publication page

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A Multi-Objective Approach for Drug Repurposing in Preeclampsia.

Molecules (Basel, Switzerland)

Tejera, Eduardo E; Pérez-Castillo, Yunierkis Y; Chamorro, Andrea A; Cabrera-Andrade, Alejandro A; Sanchez, Maria Eugenia ME

Publication Date: 2021-02-03

Variant appearance in text: ABCG2: Q126X

PubMed Link: 33546161

Variant Present in the following documents:

• molecules-26-00777.pdf

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Racial Disparity in Drug Disposition in the Digestive Tract.

International Journal Of Molecular Sciences

Gao, Song S; Bell, Edward C EC; Zhang, Yun Y; Liang, Dong D

Publication Date: 2021-01-21

Variant appearance in text: ABCG2: Q126X

PubMed Link: 33494365

Variant Present in the following documents:

• ijms-22-01038.pdf

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Common germline-somatic variant interactions in advanced urothelial cancer.

Nature Communications

Vosoughi, Aram A; Zhang, Tuo T; Shohdy, Kyrillus S KS; Vlachostergios, Panagiotis J PJ; Wilkes, David C DC; Bhinder, Bhavneet B; Tagawa, Scott T ST; Nanus, David M DM; Molina, Ana M AM; Beltran, Himisha H; Sternberg, Cora N CN; Motanagh, Samaneh S; Robinson, Brian D BD; Xiang, Jenny J; Fan, Xiao X; Chung, Wendy K WK; Rubin, Mark A MA; Elemento, Olivier O; Sboner, Andrea A; Mosquera, Juan Miguel JM; Faltas, Bishoy M BM

Publication Date: 2020-12-03

Variant appearance in text: ABCG2: 376C>T; Gln126*; rs72552713

PubMed Link: 33273457

Variant Present in the following documents:

• 41467_2020_19971_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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The association between genetic polymorphisms in ABCG2 and SLC2A9 and urate: an updated systematic review and meta-analysis.

Bmc Medical Genetics

Lukkunaprasit, Thitiya T; Rattanasiri, Sasivimol S; Turongkaravee, Saowalak S; Suvannang, Naravut N; Ingsathit, Atiporn A; Attia, John J; Thakkinstian, Ammarin A

Publication Date: 2020-10-21

Variant appearance in text: ABCG2: Q126X; rs72552713

PubMed Link: 33087043

Variant Present in the following documents:

• Main text
• 12881_2020_Article_1147.pdf

View BVdb publication page

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Comprehensive Analysis of ABCG2 Genetic Variation in the Polish Population and Its Inter-Population Comparison.

Genes

Słomka, Marcin M; Sobalska-Kwapis, Marta M; Korycka-Machała, Małgorzata M; Dziadek, Jarosław J; Bartosz, Grzegorz G; Strapagiel, Dominik D

Publication Date: 2020-09-29

Variant appearance in text: ABCG2: 376C>T; Gln126Ter; rs72552713

PubMed Link: 33003314

Variant Present in the following documents:

• Main text

View BVdb publication page

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Picky ABCG5/G8 and promiscuous ABCG2 - a tale of fatty diets and drug toxicity.

Febs Letters

Khunweeraphong, Narakorn N; Mitchell-White, James J; Szöllősi, Dániel D; Hussein, Toka T; Kuchler, Karl K; Kerr, Ian D ID; Stockner, Thomas T; Lee, Jyh-Yeuan JY

Publication Date: 2020-12

Variant appearance in text: ABCG2: Q126X

PubMed Link: 32978801

Variant Present in the following documents:

• Main text
• FEB2-594-4035.pdf

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Long-Term Safety and Effectiveness of the Xanthine Oxidoreductase Inhibitor, Topiroxostat in Japanese Hyperuricemic Patients with or Without Gout: A 54-week Open-label, Multicenter, Post-marketing Observational Study.

Clinical Drug Investigation

Ishikawa, Tomohiko T; Maeda, Tatsushi T; Hashimoto, Teruo T; Nakagawa, Tetsuya T; Ichikawa, Kazuhito K; Sato, Yasushi Y; Kanno, Yoshihiko Y

Publication Date: 2020-09

Variant appearance in text: ABCG2: Q126X; rs72552713

PubMed Link: 32621143

Variant Present in the following documents:

• Main text
• 40261_2020_Article_941.pdf

View BVdb publication page

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Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing.

Clinical Pharmacokinetics

Yin, Anyue A; Ettaieb, Madeleine H T MHT; Swen, Jesse J JJ; van Deun, Liselotte L; Kerkhofs, Thomas M A TMA; van der Straaten, Robert J H M RJHM; Corssmit, Eleonora P M EPM; Gelderblom, Hans H; Kerstens, Michiel N MN; Feelders, Richard A RA; Eekhoff, Marelise M; Timmers, Henri J L M HJLM; D'Avolio, Antonio A; Cusato, Jessica J; Guchelaar, Henk-Jan HJ; Haak, Harm R HR; Moes, Dirk Jan A R DJAR

Publication Date: 2021-01

Variant appearance in text: ABCG2: 376C>T; Q126X; rs72552713

PubMed Link: 32607875

Variant Present in the following documents:

• 40262_2020_913_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Pharmacologic inducers of the uric acid exporter ABCG2 as potential drugs for treatment of gouty arthritis.

Asian Journal Of Pharmaceutical Sciences

Ristic, Bojana B; Sikder, Mohd Omar Faruk MOF; Bhutia, Yangzom D YD; Ganapathy, Vadivel V

Publication Date: 2020-03

Variant appearance in text: ABCG2: Q126X

PubMed Link: 32373197

Variant Present in the following documents:

• Main text
• main.pdf

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Donor-derived hypouricemia in irrelevant recipients caused by kidney transplantation.

Annals Of Translational Medicine

Teng, Lisha L; Zhang, Yanling Y; Ye, Luxi L; Lv, Junhao J; Mao, Youying Y; Schneider, Ronen R; Chen, Jianghua J; Jiang, Hong H; Wu, Jianyong J

Publication Date: 2020-03

Variant appearance in text: ABCG2: Q126X

PubMed Link: 32355774

Variant Present in the following documents:

• Main text
• atm-08-06-330.pdf

View BVdb publication page

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Dysfunctional ABCG2 gene polymorphisms are associated with serum uric acid levels and all-cause mortality in hemodialysis patients.

Human Cell

Nakashima, Akio A; Ichida, Kimiyoshi K; Ohkido, Ichiro I; Yokoyama, Keitaro K; Matsuo, Hirotaka H; Ohashi, Yuki Y; Takada, Tappei T; Nakayama, Akiyoshi A; Suzuki, Hiroshi H; Shinomiya, Nariyoshi N; Urashima, Mitsuyoshi M; Yokoo, Takashi T

Publication Date: 2020-07

Variant appearance in text: ABCG2: Q126X; rs72552713

PubMed Link: 32180207

Variant Present in the following documents:

• Main text

View BVdb publication page

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Unraveling the genetic causes in large pedigrees with gout by whole‑exome sequencing.

International Journal Of Molecular Medicine

Xia, Xiaoru X; Jin, Jing J; Chen, Zhen-Ji ZJ; Zhou, Zhenni Z; Chen, Hui H; Zhang, Chunwu C; Zhang, Linhua L; Sun, Li L

Publication Date: 2020-04

Variant appearance in text: ABCG2: Gln126Ter; rs72552713

PubMed Link: 32124961

Variant Present in the following documents:

• Main text
• ijmm-45-04-1047.pdf

View BVdb publication page

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Next-Generation Sequencing Technologies in Blood Group Typing.

Transfusion Medicine And Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur Transfusionsmedizin Und Immunhamatologie

Fürst, Daniel D; Tsamadou, Chrysanthi C; Neuchel, Christine C; Schrezenmeier, Hubert H; Mytilineos, Joannis J; Weinstock, Christof C

Publication Date: 2020-02

Variant appearance in text: ABCG2: 376C>T; Gln126X; rs72552713

PubMed Link: 32110189

Variant Present in the following documents:

• Main text

View BVdb publication page

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Interaction of the p.Q141K Variant of the ABCG2 Gene with Clinical Data and Cytokine Levels in Primary Hyperuricemia and Gout.

Journal Of Clinical Medicine

Horváthová, Veronika V; Bohatá, Jana J; Pavlíková, Markéta M; Pavelcová, Kateřina K; Pavelka, Karel K; Šenolt, Ladislav L; Stibůrková, Blanka B

Publication Date: 2019-11-14

Variant appearance in text: ABCG2: Q126X; rs72552713

PubMed Link: 31739430

Variant Present in the following documents:

• Main text

View BVdb publication page

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Familial early-onset hyperuricemia and gout associated with a newly identified dysfunctional variant in urate transporter ABCG2.

Arthritis Research & Therapy

Toyoda, Yu Y; Pavelcová, Kateřina K; Klein, Martin M; Suzuki, Hiroshi H; Takada, Tappei T; Stiburkova, Blanka B

Publication Date: 2019-10-28

Variant appearance in text: ABCG2: 376C>T; Q126X

PubMed Link: 31661014

Variant Present in the following documents:

• Main text
• 13075_2019_Article_2007.pdf

View BVdb publication page

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Cellular Processing of the ABCG2 Transporter-Potential Effects on Gout and Drug Metabolism.

Cells

Mózner, Orsolya O; Bartos, Zsuzsa Z; Zámbó, Boglárka B; Homolya, László L; Hegedűs, Tamás T; Sarkadi, Balázs B

Publication Date: 2019-10-08

Variant appearance in text: ABCG2: Q126X

PubMed Link: 31597297

Variant Present in the following documents:

• Main text
• cells-08-01215.pdf

View BVdb publication page

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Development of precision medicine approaches based on inter-individual variability of BCRP/ABCG2.

Acta Pharmaceutica Sinica. B

Chen, Liming L; Manautou, Jose E JE; Rasmussen, Theodore P TP; Zhong, Xiao-Bo XB

Publication Date: 2019-07

Variant appearance in text: rs72552713

PubMed Link: 31384528

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Cellular expression and function of naturally occurring variants of the human ABCG2 multidrug transporter.

Cellular And Molecular Life Sciences : Cmls

Zámbó, Boglárka B; Mózner, Orsolya O; Bartos, Zsuzsa Z; Török, György G; Várady, György G; Telbisz, Ágnes Á; Homolya, László L; Orbán, Tamás I TI; Sarkadi, Balázs B

Publication Date: 2020-01

Variant appearance in text: ABCG2: Q126X

PubMed Link: 31254042

Variant Present in the following documents:

• Main text

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Evolving neoantigen profiles in colorectal cancers with DNA repair defects.

Genome Medicine

Rospo, Giuseppe G; Lorenzato, Annalisa A; Amirouchene-Angelozzi, Nabil N; Magrì, Alessandro A; Cancelliere, Carlotta C; Corti, Giorgio G; Negrino, Carola C; Amodio, Vito V; Montone, Monica M; Bartolini, Alice A; Barault, Ludovic L; Novara, Luca L; Isella, Claudio C; Medico, Enzo E; Bertotti, Andrea A; Trusolino, Livio L; Germano, Giovanni G; Di Nicolantonio, Federica F; Bardelli, Alberto A

Publication Date: 2019-06-28

Variant appearance in text: ABCG2: Q126*

PubMed Link: 31253177

Variant Present in the following documents:

• 13073_2019_654_MOESM2_ESM.xlsx, sheet 54

View BVdb publication page

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