SNCA c.307-32143T>C

Variant ID: 4-90682571-A-G

NM_000345.3(SNCA):c.307-32143T>C

This variant was identified in 21 publications

View GRCh38 version.




Publications:


Genetics of Neurogenic Orthostatic Hypotension in Parkinson's Disease, Results from a Cross-Sectional In Silico Study.

Brain Sciences
Chevalier, Guenson G; Udovin, Lucas L; Otero-Losada, Matilde M; Bordet, Sofia S; Capani, Francisco F; Luo, Sheng S; Goetz, Christopher G CG; Perez-Lloret, Santiago S
Publication Date: 2023-03-17

Variant appearance in text: rs3910105
PubMed Link: 36979316
Variant Present in the following documents:
  • Main text
  • brainsci-13-00506.pdf
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Machine learning-based prediction of cognitive outcomes in de novo Parkinson's disease.

Npj Parkinson'S Disease
Harvey, Joshua J; Reijnders, Rick A RA; Cavill, Rachel R; Duits, Annelien A; Köhler, Sebastian S; Eijssen, Lars L; Rutten, Bart P F BPF; Shireby, Gemma G; Torkamani, Ali A; Creese, Byron B; Leentjens, Albert F G AFG; Lunnon, Katie K; Pishva, Ehsan E
Publication Date: 2022-11-07

Variant appearance in text: rs3910105
PubMed Link: 36344548
Variant Present in the following documents:
  • Main text
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Impact of cognition-related single nucleotide polymorphisms on brain imaging phenotype in Parkinson's disease.

Neural Regeneration Research
Shen, Ting T; Pu, Jia-Li JL; Jiang, Ya-Si YS; Yue, Yu-Mei YM; He, Ting-Ting TT; Qu, Bo-Yi BY; Zhao, Shuai S; Yan, Ya-Ping YP; Lai, Hsin-Yi HY; Zhang, Bao-Rong BR
Publication Date: 2023-05

Variant appearance in text: rs3910105
PubMed Link: 36255006
Variant Present in the following documents:
  • Main text
  • NRR-18-1154.pdf
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Multi-predictor modeling for predicting early Parkinson's disease and non-motor symptoms progression.

Frontiers In Aging Neuroscience
Dou, Kaixin K; Ma, Jiangnan J; Zhang, Xue X; Shi, Wanda W; Tao, Mingzhu M; Xie, Anmu A
Publication Date: 2022

Variant appearance in text: rs3910105
PubMed Link: 36092799
Variant Present in the following documents:
  • Main text
  • fnagi-14-977985.pdf
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Predicting the onset of freezing of gait in Parkinson's disease.

Bmc Neurology
Wang, Fengting F; Pan, Yixin Y; Zhang, Miao M; Hu, Kejia K
Publication Date: 2022-06-07

Variant appearance in text: rs3910105
PubMed Link: 35672669
Variant Present in the following documents:
  • Main text
  • 12883_2022_Article_2713.pdf
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SNCA rs3910105 Is Associated With Development of Rapid Eye Movement Sleep Behavior Disorder in Parkinson's Disease.

Frontiers In Neuroscience
Yang, Nan-Nan NN; Sang, Shu-Shan SS; Peng, Tao T; Lu, Hong H
Publication Date: 2022

Variant appearance in text: rs3910105
PubMed Link: 35310107
Variant Present in the following documents:
  • Main text
  • fnins-16-832550.pdf
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A systematic review of associations between common SNCA variants and clinical heterogeneity in Parkinson's disease.

Npj Parkinson'S Disease
Pedersen, Camilla Christina CC; Lange, Johannes J; Førland, Marthe Gurine Gunnarsdatter MGG; Macleod, Angus D AD; Alves, Guido G; Maple-Grødem, Jodi J
Publication Date: 2021-07-01

Variant appearance in text: rs3910105
PubMed Link: 34210990
Variant Present in the following documents:
  • 41531_2021_196_MOESM1_ESM.pdf
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Transcript Variants of Genes Involved in Neurodegeneration Are Differentially Regulated by the APOE and MAPT Haplotypes.

Genes
Koks, Sulev S; Pfaff, Abigail L AL; Bubb, Vivien J VJ; Quinn, John P JP
Publication Date: 2021-03-15

Variant appearance in text: rs3910105
PubMed Link: 33804213
Variant Present in the following documents:
  • Main text
  • genes-12-00423.pdf
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Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson's Disease Progression.

Movement Disorders : Official Journal Of The Movement Disorder Society
Mollenhauer, Brit B; Dakna, Mohammed M; Kruse, Niels N; Galasko, Douglas D; Foroud, Tatiana T; Zetterberg, Henrik H; Schade, Sebastian S; Gera, Roland G RG; Wang, Wenting W; Gao, Feng F; Frasier, Mark M; Chahine, Lana M LM; Coffey, Christopher S CS; Singleton, Andrew B AB; Simuni, Tanya T; Weintraub, Daniel D; Seibyl, John J; Toga, Arthur W AW; Tanner, Caroline M CM; Kieburtz, Karl K; Marek, Kenneth K; Siderowf, Andrew A; Cedarbaum, Jesse M JM; Hutten, Samantha J SJ; Trenkwalder, Claudia C; Graham, Danielle D
Publication Date: 2020-11

Variant appearance in text: rs3910105
PubMed Link: 32798333
Variant Present in the following documents:
  • Main text
  • nihms-1682170.pdf
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Prediction of age at onset in Parkinson's disease using objective specific neuroimaging genetics based on a sparse canonical correlation analysis.

Scientific Reports
Won, Ji Hye JH; Kim, Mansu M; Youn, Jinyoung J; Park, Hyunjin H
Publication Date: 2020-07-15

Variant appearance in text: rs3910105
PubMed Link: 32669683
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_68301.pdf
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Parkinson's disease prognostic scores for progression of cognitive decline.

Scientific Reports
Gramotnev, Galina G; Gramotnev, Dmitri K DK; Gramotnev, Alexandra A
Publication Date: 2019-11-25

Variant appearance in text: rs3910105
PubMed Link: 31767922
Variant Present in the following documents:
  • Main text
  • 41598_2019_Article_54029.pdf
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Longitudinal analyses of cerebrospinal fluid α-Synuclein in prodromal and early Parkinson's disease.

Movement Disorders : Official Journal Of The Movement Disorder Society
Mollenhauer, Brit B; Caspell-Garcia, Chelsea J CJ; Coffey, Christopher S CS; Taylor, Peggy P; Singleton, Andy A; Shaw, Leslie M LM; Trojanowski, John Q JQ; Frasier, Mark M; Simuni, Tanya T; Iranzo, Alex A; Oertel, Wolfgang W; Siderowf, Andrew A; Weintraub, Daniel D; Seibyl, John J; Toga, Arthur W AW; Tanner, Caroline M CM; Kieburtz, Karl K; Chahine, Lana M LM; Marek, Kenneth K; Galasko, Douglas D; ,
Publication Date: 2019-09

Variant appearance in text: rs3910105
PubMed Link: 31361367
Variant Present in the following documents:
  • Main text
  • nihms-1567236.pdf
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Effect of Single-Nucleotide Polymorphisms on Decline of Dopamine Transporter Availability in Parkinson's Disease.

Journal Of Clinical Neurology (Seoul, Korea)
Shin, Seunghyeon S; Kim, Keunyoung K; Lee, Jae Meen JM; Kim, Eun Joo EJ; Kim, Seong Jang SJ; Kim, In Joo IJ; Pak, Kyoungjune K; Lee, Myung Jun MJ
Publication Date: 2019-01

Variant appearance in text: rs3910105
PubMed Link: 30618224
Variant Present in the following documents:
  • Main text
  • jcn-15-102.pdf
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Effect of rs3910105 in the Synuclein Gene on Dopamine Transporter Availability in Healthy Subjects.

Yonsei Medical Journal
Seo, Youngduk Y; Pak, Kyoungjune K; Nam, Hyun Yeol HY; Seok, Ju Won JW; Lee, Myung Jun MJ; Kim, Eun Joo EJ; Lee, Jae Meen JM; Kim, Seong Jang SJ; Kim, In Joo IJ
Publication Date: 2018-08

Variant appearance in text: rs3910105
PubMed Link: 29978616
Variant Present in the following documents:
  • Main text
  • ymj-59-787.pdf
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Longitudinal CSF biomarkers in patients with early Parkinson disease and healthy controls.

Neurology
Mollenhauer, Brit B; Caspell-Garcia, Chelsea J CJ; Coffey, Christopher S CS; Taylor, Peggy P; Shaw, Leslie M LM; Trojanowski, John Q JQ; Singleton, Andy A; Frasier, Mark M; Marek, Kenneth K; Galasko, Douglas D; ,
Publication Date: 2017-11-07

Variant appearance in text: rs3910105
PubMed Link: 29030452
Variant Present in the following documents:
  • Main text
  • NEUROLOGY2017801936.pdf
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Regional analysis and genetic association of nigrostriatal degeneration in Lewy body disease.

Movement Disorders : Official Journal Of The Movement Disorder Society
Kasanuki, Koji K; Heckman, Michael G MG; Diehl, Nancy N NN; Murray, Melissa E ME; Koga, Shunsuke S; Soto, Alexandra A; Ross, Owen A OA; Dickson, Dennis W DW
Publication Date: 2017-11

Variant appearance in text: rs3910105
PubMed Link: 28949048
Variant Present in the following documents:
  • Main text
View BVdb publication page



Parkinson's disease susceptibility variants and severity of Lewy body pathology.

Parkinsonism & Related Disorders
Heckman, Michael G MG; Kasanuki, Koji K; Diehl, Nancy N NN; Koga, Shunsuke S; Soto, Alexandra A; Murray, Melissa E ME; Dickson, Dennis W DW; Ross, Owen A OA
Publication Date: 2017-11

Variant appearance in text: rs3910105
PubMed Link: 28917824
Variant Present in the following documents:
  • Main text
View BVdb publication page



Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease.

Plos One
Caspell-Garcia, Chelsea C; Simuni, Tanya T; Tosun-Turgut, Duygu D; Wu, I-Wei IW; Zhang, Yu Y; Nalls, Mike M; Singleton, Andrew A; Shaw, Leslie A LA; Kang, Ju-Hee JH; Trojanowski, John Q JQ; Siderowf, Andrew A; Coffey, Christopher C; Lasch, Shirley S; Aarsland, Dag D; Burn, David D; Chahine, Lana M LM; Espay, Alberto J AJ; Foster, Eric D ED; Hawkins, Keith A KA; Litvan, Irene I; Richard, Irene I; Weintraub, Daniel D; ,
Publication Date: 2017

Variant appearance in text: rs3910105
PubMed Link: 28520803
Variant Present in the following documents:
  • Main text
  • pone.0175674.pdf
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Genome-wide assessment of Parkinson's disease in a Southern Spanish population.

Neurobiology Of Aging
Bandrés-Ciga, Sara S; Price, Timothy Ryan TR; Barrero, Francisco Javier FJ; Escamilla-Sevilla, Francisco F; Pelegrina, Javier J; Arepalli, Sampath S; Hernández, Dena D; Gutiérrez, Blanca B; Cervilla, Jorge J; Rivera, Margarita M; Rivera, Alberto A; Ding, Jing-Hui JH; Vives, Francisco F; Nalls, Michael M; Singleton, Andrew A; Durán, Raquel R
Publication Date: 2016-09

Variant appearance in text: rs3910105
PubMed Link: 27393345
Variant Present in the following documents:
  • Main text
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CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study.

Acta Neuropathologica
Kang, Ju-Hee JH; Mollenhauer, Brit B; Coffey, Christopher S CS; Toledo, Jon B JB; Weintraub, Daniel D; Galasko, Douglas R DR; Irwin, David J DJ; Van Deerlin, Vivianna V; Chen-Plotkin, Alice S AS; Caspell-Garcia, Chelsea C; Waligórska, Teresa T; Taylor, Peggy P; Shah, Nirali N; Pan, Sarah S; Zero, Pawel P; Frasier, Mark M; Marek, Kenneth K; Kieburtz, Karl K; Jennings, Danna D; Tanner, Caroline M CM; Simuni, Tanya T; Singleton, Andrew A; Toga, Arthur W AW; Chowdhury, Sohini S; Trojanowski, John Q JQ; Shaw, Leslie M LM; ,
Publication Date: 2016-06

Variant appearance in text: rs3910105
PubMed Link: 27021906
Variant Present in the following documents:
  • Main text
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Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.

Nature Genetics
Nalls, Mike A MA; Pankratz, Nathan N; Lill, Christina M CM; Do, Chuong B CB; Hernandez, Dena G DG; Saad, Mohamad M; DeStefano, Anita L AL; Kara, Eleanna E; Bras, Jose J; Sharma, Manu M; Schulte, Claudia C; Keller, Margaux F MF; Arepalli, Sampath S; Letson, Christopher C; Edsall, Connor C; Stefansson, Hreinn H; Liu, Xinmin X; Pliner, Hannah H; Lee, Joseph H JH; Cheng, Rong R; , ; , ; , ; , ; , ; , ; , ; , ; , ; , ; , ; , ; Ikram, M Arfan MA; Ioannidis, John P A JP; Hadjigeorgiou, Georgios M GM; Bis, Joshua C JC; Martinez, Maria M; Perlmutter, Joel S JS; Goate, Alison A; Marder, Karen K; Fiske, Brian B; Sutherland, Margaret M; Xiromerisiou, Georgia G; Myers, Richard H RH; Clark, Lorraine N LN; Stefansson, Kari K; Hardy, John A JA; Heutink, Peter P; Chen, Honglei H; Wood, Nicholas W NW; Houlden, Henry H; Payami, Haydeh H; Brice, Alexis A; Scott, William K WK; Gasser, Thomas T; Bertram, Lars L; Eriksson, Nicholas N; Foroud, Tatiana T; Singleton, Andrew B AB
Publication Date: 2014-09

Variant appearance in text: rs3910105
PubMed Link: 25064009
Variant Present in the following documents:
  • Main text
  • NIHMS610183-supplement-1.pdf
View BVdb publication page