SNCA c.226G>C ;(p.A76P)

Variant ID: 4-90743477-C-G

NM_000345.3(SNCA):c.226G>C;(p.A76P)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


α-Synuclein at the Presynaptic Axon Terminal as a Double-Edged Sword.

Biomolecules
Tan, Li Yang LY; Tang, Kwan Hou KH; Lim, Lynette Yu You LYY; Ong, Jia Xin JX; Park, Hyokeun H; Jung, Sangyong S
Publication Date: 2022-03-27

Variant appearance in text: SNCA: A76P
PubMed Link: 35454096
Variant Present in the following documents:
  • Main text
  • biomolecules-12-00507.pdf
View BVdb publication page



Computational insights into the role of α-strand/sheet in aggregation of α-synuclein.

Scientific Reports
Balupuri, Anand A; Choi, Kwang-Eun KE; Kang, Nam Sook NS
Publication Date: 2019-01-11

Variant appearance in text: NACP: A76P
PubMed Link: 30635607
Variant Present in the following documents:
  • 41598_2018_Article_37276.pdf
View BVdb publication page



Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation.

Plos Genetics
Lázaro, Diana F DF; Rodrigues, Eva F EF; Langohr, Ramona R; Shahpasandzadeh, Hedieh H; Ribeiro, Thales T; Guerreiro, Patrícia P; Gerhardt, Ellen E; Kröhnert, Katharina K; Klucken, Jochen J; Pereira, Marcos D MD; Popova, Blagovesta B; Kruse, Niels N; Mollenhauer, Brit B; Rizzoli, Silvio O SO; Braus, Gerhard H GH; Danzer, Karin M KM; Outeiro, Tiago F TF
Publication Date: 2014-11

Variant appearance in text: SNCA: A76P
PubMed Link: 25393002
Variant Present in the following documents:
  • Main text
  • pgen.1004741.pdf
View BVdb publication page



The many faces of α-synuclein: from structure and toxicity to therapeutic target.

Nature Reviews. Neuroscience
Lashuel, Hilal A HA; Overk, Cassia R CR; Oueslati, Abid A; Masliah, Eliezer E
Publication Date: 2013-01

Variant appearance in text: SNCA: A76P
PubMed Link: 23254192
Variant Present in the following documents:
  • Main text
View BVdb publication page



α-Synuclein oligomers and clinical implications for Parkinson disease.

Annals Of Neurology
Kalia, Lorraine V LV; Kalia, Suneil K SK; McLean, Pamela J PJ; Lozano, Andres M AM; Lang, Anthony E AE
Publication Date: 2013-02

Variant appearance in text: SNCA: A76P
PubMed Link: 23225525
Variant Present in the following documents:
  • Main text
View BVdb publication page



Characterization of hydrophobic residue requirements for alpha-synuclein fibrillization.

Biochemistry
Waxman, Elisa A EA; Mazzulli, Joseph R JR; Giasson, Benoit I BI
Publication Date: 2009-10-13

Variant appearance in text: SNCA: A76P
PubMed Link: 19722699
Variant Present in the following documents:
  • Main text
View BVdb publication page