In Silico Study of the Interactions of Anle138b Isomer, an Inhibitor of Amyloid Aggregation, with Partner Proteins.
International Journal Of Molecular Sciences
Kondratyev, Maxim S MS; Rudnev, Vladimir R VR; Nikolsky, Kirill S KS; Petrovsky, Denis V DV; Kulikova, Liudmila I LI; Malsagova, Kristina A KA; Stepanov, Alexander A AA; Kopylov, Arthur T AT; Kaysheva, Anna L AL
A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity.
Science Advances
Kumar, Senthil T ST; Mahul-Mellier, Anne-Laure AL; Hegde, Ramanath Narayana RN; Rivière, Gwladys G; Moons, Rani R; Ibáñez de Opakua, Alain A; Magalhães, Pedro P; Rostami, Iman I; Donzelli, Sonia S; Sobott, Frank F; Zweckstetter, Markus M; Lashuel, Hilal A HA
Alpha-synuclein research: defining strategic moves in the battle against Parkinson's disease.
Npj Parkinson'S Disease
Oliveira, Luis M A LMA; Gasser, Thomas T; Edwards, Robert R; Zweckstetter, Markus M; Melki, Ronald R; Stefanis, Leonidas L; Lashuel, Hilal A HA; Sulzer, David D; Vekrellis, Kostas K; Halliday, Glenda M GM; Tomlinson, Julianna J JJ; Schlossmacher, Michael M; Jensen, Poul Henning PH; Schulze-Hentrich, Julia J; Riess, Olaf O; Hirst, Warren D WD; El-Agnaf, Omar O; Mollenhauer, Brit B; Lansbury, Peter P; Outeiro, Tiago F TF
Accumulation of alpha-synuclein within the liver, potential role in the clearance of brain pathology associated with Parkinson's disease.
Acta Neuropathologica Communications
Reyes, Juan F JF; Ekmark-Léwen, Sara S; Perdiki, Marina M; Klingstedt, Therése T; Hoffmann, Alana A; Wiechec, Emilia E; Nilsson, Per P; Nilsson, K Peter R KPR; Alafuzoff, Irina I; Ingelsson, Martin M; Hallbeck, Martin M
Interaction of Alpha-Synuclein With Lipids: Mitochondrial Cardiolipin as a Critical Player in the Pathogenesis of Parkinson's Disease.
Frontiers In Neuroscience
Gilmozzi, Valentina V; Gentile, Giovanna G; Castelo Rueda, Maria Paulina MP; Hicks, Andrew A AA; Pramstaller, Peter P PP; Zanon, Alessandra A; Lévesque, Martin M; Pichler, Irene I
α-Synuclein filaments from transgenic mouse and human synucleinopathy-containing brains are major seed-competent species.
The Journal Of Biological Chemistry
Morgan, Sophie A SA; Lavenir, Isabelle I; Fan, Juan J; Masuda-Suzukake, Masami M; Passarella, Daniela D; DeTure, Michael A MA; Dickson, Dennis W DW; Ghetti, Bernardino B; Goedert, Michel M