SNCA c.116A>T ;(p.Y39F)

Variant ID: 4-90756703-T-A

NM_000345.3(SNCA):c.116A>T;(p.Y39F)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes and Cellular Toxicity.

Molecules (Basel, Switzerland)
Xu, Catherine K CK; Castellana-Cruz, Marta M; Chen, Serene W SW; Du, Zhen Z; Meisl, Georg G; Levin, Aviad A; Mannini, Benedetta B; Itzhaki, Laura S LS; Knowles, Tuomas P J TPJ; Dobson, Christopher M CM; Cremades, Nunilo N; Kumita, Janet R JR
Publication Date: 2022-02-15

Variant appearance in text: SNCA: Y39F
PubMed Link: 35209093
Variant Present in the following documents:
  • molecules-27-01293.pdf
View BVdb publication page



Modulation of the Interactions Between α-Synuclein and Lipid Membranes by Post-translational Modifications.

Frontiers In Neurology
Bell, Rosie R; Vendruscolo, Michele M
Publication Date: 2021

Variant appearance in text: SNCA: Y39F
PubMed Link: 34335440
Variant Present in the following documents:
  • Main text
  • fneur-12-661117.pdf
View BVdb publication page



α-synuclein-lanthanide metal ions interaction: binding sites, conformation and fibrillation.

Bmc Biophysics
Bai, Jia J; Zhang, Zeting Z; Liu, Maili M; Li, Conggang C
Publication Date: 2015

Variant appearance in text: NACP: Y39F
PubMed Link: 26843956
Variant Present in the following documents:
  • 13628_2016_Article_26.pdf
View BVdb publication page



c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease.

Human Molecular Genetics
Mahul-Mellier, Anne-Laure AL; Fauvet, Bruno B; Gysbers, Amanda A; Dikiy, Igor I; Oueslati, Abid A; Georgeon, Sandrine S; Lamontanara, Allan J AJ; Bisquertt, Alejandro A; Eliezer, David D; Masliah, Eliezer E; Halliday, Glenda G; Hantschel, Oliver O; Lashuel, Hilal A HA
Publication Date: 2014-06-01

Variant appearance in text: SNCA: Y39F
PubMed Link: 24412932
Variant Present in the following documents:
  • Main text
View BVdb publication page