Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Genetics of Neurogenic Orthostatic Hypotension in Parkinson's Disease, Results from a Cross-Sectional In Silico Study.
Brain Sciences
Chevalier, Guenson G; Udovin, Lucas L; Otero-Losada, Matilde M; Bordet, Sofia S; Capani, Francisco F; Luo, Sheng S; Goetz, Christopher G CG; Perez-Lloret, Santiago S
Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects.
Nature Communications
Krohn, Lynne L; Heilbron, Karl K; Blauwendraat, Cornelis C; Reynolds, Regina H RH; Yu, Eric E; Senkevich, Konstantin K; Rudakou, Uladzislau U; Estiar, Mehrdad A MA; Gustavsson, Emil K EK; Brolin, Kajsa K; Ruskey, Jennifer A JA; Freeman, Kathryn K; Asayesh, Farnaz F; Chia, Ruth R; Arnulf, Isabelle I; Hu, Michele T M MTM; Montplaisir, Jacques Y JY; Gagnon, Jean-François JF; Desautels, Alex A; Dauvilliers, Yves Y; Gigli, Gian Luigi GL; Valente, Mariarosaria M; Janes, Francesco F; Bernardini, Andrea A; Högl, Birgit B; Stefani, Ambra A; Ibrahim, Abubaker A; Šonka, Karel K; Kemlink, David D; Oertel, Wolfgang W; Janzen, Annette A; Plazzi, Giuseppe G; Biscarini, Francesco F; Antelmi, Elena E; Figorilli, Michela M; Puligheddu, Monica M; Mollenhauer, Brit B; Trenkwalder, Claudia C; Sixel-Döring, Friederike F; Cochen De Cock, Valérie V; Monaca, Christelle Charley CC; Heidbreder, Anna A; Ferini-Strambi, Luigi L; Dijkstra, Femke F; Viaene, Mineke M; Abril, Beatriz B; Boeve, Bradley F BF; , ; Scholz, Sonja W SW; Ryten, Mina M; Bandres-Ciga, Sara S; Noyce, Alastair A; Cannon, Paul P; Pihlstrøm, Lasse L; Nalls, Mike A MA; Singleton, Andrew B AB; Rouleau, Guy A GA; Postuma, Ronald B RB; Gan-Or, Ziv Z
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Pinpointing novel risk loci for Lewy body dementia and the shared genetic etiology with Alzheimer's disease and Parkinson's disease: a large-scale multi-trait association analysis.
Bmc Medicine
Guo, Ping P; Gong, Weiming W; Li, Yuanming Y; Liu, Lu L; Yan, Ran R; Wang, Yanjun Y; Zhang, Yanan Y; Yuan, Zhongshang Z
Establishing gene regulatory networks from Parkinson's disease risk loci.
Brain : A Journal Of Neurology
Farrow, Sophie L SL; Schierding, William W; Gokuladhas, Sreemol S; Golovina, Evgeniia E; Fadason, Tayaza T; Cooper, Antony A AA; O'Sullivan, Justin M JM
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.
Nature Genetics
van Rheenen, Wouter W; van der Spek, Rick A A RAA; Bakker, Mark K MK; van Vugt, Joke J F A JJFA; Hop, Paul J PJ; Zwamborn, Ramona A J RAJ; de Klein, Niek N; Westra, Harm-Jan HJ; Bakker, Olivier B OB; Deelen, Patrick P; Shireby, Gemma G; Hannon, Eilis E; Moisse, Matthieu M; Baird, Denis D; Restuadi, Restuadi R; Dolzhenko, Egor E; Dekker, Annelot M AM; Gawor, Klara K; Westeneng, Henk-Jan HJ; Tazelaar, Gijs H P GHP; van Eijk, Kristel R KR; Kooyman, Maarten M; Byrne, Ross P RP; Doherty, Mark M; Heverin, Mark M; Al Khleifat, Ahmad A; Iacoangeli, Alfredo A; Shatunov, Aleksey A; Ticozzi, Nicola N; Cooper-Knock, Johnathan J; Smith, Bradley N BN; Gromicho, Marta M; Chandran, Siddharthan S; Pal, Suvankar S; Morrison, Karen E KE; Shaw, Pamela J PJ; Hardy, John J; Orrell, Richard W RW; Sendtner, Michael M; Meyer, Thomas T; Başak, Nazli N; van der Kooi, Anneke J AJ; Ratti, Antonia A; Fogh, Isabella I; Gellera, Cinzia C; Lauria, Giuseppe G; Corti, Stefania S; Cereda, Cristina C; Sproviero, Daisy D; D'Alfonso, Sandra S; Sorarù, Gianni G; Siciliano, Gabriele G; Filosto, Massimiliano M; Padovani, Alessandro A; Chiò, Adriano A; Calvo, Andrea A; Moglia, Cristina C; Brunetti, Maura M; Canosa, Antonio A; Grassano, Maurizio M; Beghi, Ettore E; Pupillo, Elisabetta E; Logroscino, Giancarlo G; Nefussy, Beatrice B; Osmanovic, Alma A; Nordin, Angelica A; Lerner, Yossef Y; Zabari, Michal M; Gotkine, Marc M; Baloh, Robert H RH; Bell, Shaughn S; Vourc'h, Patrick P; Corcia, Philippe P; Couratier, Philippe P; Millecamps, Stéphanie S; Meininger, Vincent V; Salachas, François F; Mora Pardina, Jesus S JS; Assialioui, Abdelilah A; Rojas-García, Ricardo R; Dion, Patrick A PA; Ross, Jay P JP; Ludolph, Albert C AC; Weishaupt, Jochen H JH; Brenner, David D; Freischmidt, Axel A; Bensimon, Gilbert G; Brice, Alexis A; Durr, Alexandra A; Payan, Christine A M CAM; Saker-Delye, Safa S; Wood, Nicholas W NW; Topp, Simon S; Rademakers, Rosa R; Tittmann, Lukas L; Lieb, Wolfgang W; Franke, Andre A; Ripke, Stephan S; Braun, Alice A; Kraft, Julia J; Whiteman, David C DC; Olsen, Catherine M CM; Uitterlinden, Andre G AG; Hofman, Albert A; Rietschel, Marcella M; Cichon, Sven S; Nöthen, Markus M MM; Amouyel, Philippe P; , ; , ; , ; , ; Traynor, Bryan J BJ; Singleton, Andrew B AB; Mitne Neto, Miguel M; Cauchi, Ruben J RJ; Ophoff, Roel A RA; Wiedau-Pazos, Martina M; Lomen-Hoerth, Catherine C; van Deerlin, Vivianna M VM; Grosskreutz, Julian J; Roediger, Annekathrin A; Gaur, Nayana N; Jörk, Alexander A; Barthel, Tabea T; Theele, Erik E; Ilse, Benjamin B; Stubendorff, Beatrice B; Witte, Otto W OW; Steinbach, Robert R; Hübner, Christian A CA; Graff, Caroline C; Brylev, Lev L; Fominykh, Vera V; Demeshonok, Vera V; Ataulina, Anastasia A; Rogelj, Boris B; Koritnik, Blaž B; Zidar, Janez J; Ravnik-Glavač, Metka M; Glavač, Damjan D; Stević, Zorica Z; Drory, Vivian V; Povedano, Monica M; Blair, Ian P IP; Kiernan, Matthew C MC; Benyamin, Beben B; Henderson, Robert D RD; Furlong, Sarah S; Mathers, Susan S; McCombe, Pamela A PA; Needham, Merrilee M; Ngo, Shyuan T ST; Nicholson, Garth A GA; Pamphlett, Roger R; Rowe, Dominic B DB; Steyn, Frederik J FJ; Williams, Kelly L KL; Mather, Karen A KA; Sachdev, Perminder S PS; Henders, Anjali K AK; Wallace, Leanne L; de Carvalho, Mamede M; Pinto, Susana S; Petri, Susanne S; Weber, Markus M; Rouleau, Guy A GA; Silani, Vincenzo V; Curtis, Charles J CJ; Breen, Gerome G; Glass, Jonathan D JD; Brown, Robert H RH; Landers, John E JE; Shaw, Christopher E CE; Andersen, Peter M PM; Groen, Ewout J N EJN; van Es, Michael A MA; Pasterkamp, R Jeroen RJ; Fan, Dongsheng D; Garton, Fleur C FC; McRae, Allan F AF; Davey Smith, George G; Gaunt, Tom R TR; Eberle, Michael A MA; Mill, Jonathan J; McLaughlin, Russell L RL; Hardiman, Orla O; Kenna, Kevin P KP; Wray, Naomi R NR; Tsai, Ellen E; Runz, Heiko H; Franke, Lude L; Al-Chalabi, Ammar A; Van Damme, Philip P; van den Berg, Leonard H LH; Veldink, Jan H JH
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.
Nature Genetics
van Rheenen, Wouter W; van der Spek, Rick A A RAA; Bakker, Mark K MK; van Vugt, Joke J F A JJFA; Hop, Paul J PJ; Zwamborn, Ramona A J RAJ; de Klein, Niek N; Westra, Harm-Jan HJ; Bakker, Olivier B OB; Deelen, Patrick P; Shireby, Gemma G; Hannon, Eilis E; Moisse, Matthieu M; Baird, Denis D; Restuadi, Restuadi R; Dolzhenko, Egor E; Dekker, Annelot M AM; Gawor, Klara K; Westeneng, Henk-Jan HJ; Tazelaar, Gijs H P GHP; van Eijk, Kristel R KR; Kooyman, Maarten M; Byrne, Ross P RP; Doherty, Mark M; Heverin, Mark M; Al Khleifat, Ahmad A; Iacoangeli, Alfredo A; Shatunov, Aleksey A; Ticozzi, Nicola N; Cooper-Knock, Johnathan J; Smith, Bradley N BN; Gromicho, Marta M; Chandran, Siddharthan S; Pal, Suvankar S; Morrison, Karen E KE; Shaw, Pamela J PJ; Hardy, John J; Orrell, Richard W RW; Sendtner, Michael M; Meyer, Thomas T; Başak, Nazli N; van der Kooi, Anneke J AJ; Ratti, Antonia A; Fogh, Isabella I; Gellera, Cinzia C; Lauria, Giuseppe G; Corti, Stefania S; Cereda, Cristina C; Sproviero, Daisy D; D'Alfonso, Sandra S; Sorarù, Gianni G; Siciliano, Gabriele G; Filosto, Massimiliano M; Padovani, Alessandro A; Chiò, Adriano A; Calvo, Andrea A; Moglia, Cristina C; Brunetti, Maura M; Canosa, Antonio A; Grassano, Maurizio M; Beghi, Ettore E; Pupillo, Elisabetta E; Logroscino, Giancarlo G; Nefussy, Beatrice B; Osmanovic, Alma A; Nordin, Angelica A; Lerner, Yossef Y; Zabari, Michal M; Gotkine, Marc M; Baloh, Robert H RH; Bell, Shaughn S; Vourc'h, Patrick P; Corcia, Philippe P; Couratier, Philippe P; Millecamps, Stéphanie S; Meininger, Vincent V; Salachas, François F; Mora Pardina, Jesus S JS; Assialioui, Abdelilah A; Rojas-García, Ricardo R; Dion, Patrick A PA; Ross, Jay P JP; Ludolph, Albert C AC; Weishaupt, Jochen H JH; Brenner, David D; Freischmidt, Axel A; Bensimon, Gilbert G; Brice, Alexis A; Durr, Alexandra A; Payan, Christine A M CAM; Saker-Delye, Safa S; Wood, Nicholas W NW; Topp, Simon S; Rademakers, Rosa R; Tittmann, Lukas L; Lieb, Wolfgang W; Franke, Andre A; Ripke, Stephan S; Braun, Alice A; Kraft, Julia J; Whiteman, David C DC; Olsen, Catherine M CM; Uitterlinden, Andre G AG; Hofman, Albert A; Rietschel, Marcella M; Cichon, Sven S; Nöthen, Markus M MM; Amouyel, Philippe P; , ; , ; , ; , ; Traynor, Bryan J BJ; Singleton, Andrew B AB; Mitne Neto, Miguel M; Cauchi, Ruben J RJ; Ophoff, Roel A RA; Wiedau-Pazos, Martina M; Lomen-Hoerth, Catherine C; van Deerlin, Vivianna M VM; Grosskreutz, Julian J; Roediger, Annekathrin A; Gaur, Nayana N; Jörk, Alexander A; Barthel, Tabea T; Theele, Erik E; Ilse, Benjamin B; Stubendorff, Beatrice B; Witte, Otto W OW; Steinbach, Robert R; Hübner, Christian A CA; Graff, Caroline C; Brylev, Lev L; Fominykh, Vera V; Demeshonok, Vera V; Ataulina, Anastasia A; Rogelj, Boris B; Koritnik, Blaž B; Zidar, Janez J; Ravnik-Glavač, Metka M; Glavač, Damjan D; Stević, Zorica Z; Drory, Vivian V; Povedano, Monica M; Blair, Ian P IP; Kiernan, Matthew C MC; Benyamin, Beben B; Henderson, Robert D RD; Furlong, Sarah S; Mathers, Susan S; McCombe, Pamela A PA; Needham, Merrilee M; Ngo, Shyuan T ST; Nicholson, Garth A GA; Pamphlett, Roger R; Rowe, Dominic B DB; Steyn, Frederik J FJ; Williams, Kelly L KL; Mather, Karen A KA; Sachdev, Perminder S PS; Henders, Anjali K AK; Wallace, Leanne L; de Carvalho, Mamede M; Pinto, Susana S; Petri, Susanne S; Weber, Markus M; Rouleau, Guy A GA; Silani, Vincenzo V; Curtis, Charles J CJ; Breen, Gerome G; Glass, Jonathan D JD; Brown, Robert H RH; Landers, John E JE; Shaw, Christopher E CE; Andersen, Peter M PM; Groen, Ewout J N EJN; van Es, Michael A MA; Pasterkamp, R Jeroen RJ; Fan, Dongsheng D; Garton, Fleur C FC; McRae, Allan F AF; Davey Smith, George G; Gaunt, Tom R TR; Eberle, Michael A MA; Mill, Jonathan J; McLaughlin, Russell L RL; Hardiman, Orla O; Kenna, Kevin P KP; Wray, Naomi R NR; Tsai, Ellen E; Runz, Heiko H; Franke, Lude L; Al-Chalabi, Ammar A; Van Damme, Philip P; van den Berg, Leonard H LH; Veldink, Jan H JH
Understanding the Potential of Genome Editing in Parkinson's Disease.
International Journal Of Molecular Sciences
Arango, David D; Bittar, Amaury A; Esmeral, Natalia P NP; Ocasión, Camila C; Muñoz-Camargo, Carolina C; Cruz, Juan C JC; Reyes, Luis H LH; Bloch, Natasha I NI
Movement Disorders : Official Journal Of The Movement Disorder Society
Iwaki, Hirotaka H; Leonard, Hampton L HL; Makarious, Mary B MB; Bookman, Matt M; Landin, Barry B; Vismer, David D; Casey, Bradford B; Gibbs, J Raphael JR; Hernandez, Dena G DG; Blauwendraat, Cornelis C; Vitale, Daniel D; Song, Yeajin Y; Kumar, Dinesh D; Dalgard, Clifton L CL; Sadeghi, Mahdiar M; Dong, Xianjun X; Misquitta, Leonie L; Scholz, Sonja W SW; Scherzer, Clemens R CR; Nalls, Mike A MA; Biswas, Shameek S; Singleton, Andrew B AB; , ; , ; ,
Publication Date: 2021-08
Variant appearance in text: TMEM175: M393T; rs34311866
Variable Effects of PD-Risk Associated SNPs and Variants in Parkinsonism-Associated Genes on Disease Phenotype in a Community-Based Cohort.
Frontiers In Neurology
Markopoulou, Katerina K; Chase, Bruce A BA; Premkumar, Ashvini P AP; Schoneburg, Bernadette B; Kartha, Ninith N; Wei, Jun J; Yu, Hongjie H; Epshteyn, Alexander A; Garduno, Lisette L; Pham, Anna A; Vazquez, Rosa R; Frigerio, Roberta R; Maraganore, Demetrius D
Prioritization of candidate genes for a South African family with Parkinson's disease using in-silico tools.
Plos One
Sebate, Boiketlo B; Cuttler, Katelyn K; Cloete, Ruben R; Britz, Marcell M; Christoffels, Alan A; Williams, Monique M; Carr, Jonathan J; Bardien, Soraya S
Publication Date: 2021
Variant appearance in text: TMEM175: 1178T>C; M393T; rs34311866
Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets.
Jama Neurology
Kia, Demis A DA; Zhang, David D; Guelfi, Sebastian S; Manzoni, Claudia C; Hubbard, Leon L; Reynolds, Regina H RH; Botía, Juan J; Ryten, Mina M; Ferrari, Raffaele R; Lewis, Patrick A PA; Williams, Nigel N; Trabzuni, Daniah D; Hardy, John J; Wood, Nicholas W NW; ,
An omics-based strategy using coenzyme Q10 in patients with Parkinson's disease: concept evaluation in a double-blind randomized placebo-controlled parallel group trial.
Neurological Research And Practice
Prasuhn, Jannik J; Brüggemann, Norbert N; Hessler, Nicole N; Berg, Daniela D; Gasser, Thomas T; Brockmann, Kathrin K; Olbrich, Denise D; Ziegler, Andreas A; König, Inke R IR; Klein, Christine C; Kasten, Meike M
Fine-Mapping of SNCA in Rapid Eye Movement Sleep Behavior Disorder and Overt Synucleinopathies.
Annals Of Neurology
Krohn, Lynne L; Wu, Richard Y J RYJ; Heilbron, Karl K; Ruskey, Jennifer A JA; Laurent, Sandra B SB; Blauwendraat, Cornelis C; Alam, Armaghan A; Arnulf, Isabelle I; Hu, Michele T M MTM; Dauvilliers, Yves Y; Högl, Birgit B; Toft, Mathias M; Bjørnarå, Kari Anne KA; Stefani, Ambra A; Holzknecht, Evi E; Monaca, Christelle Charley CC; Abril, Beatriz B; Plazzi, Giuseppe G; Antelmi, Elena E; Ferini-Strambi, Luigi L; Young, Peter P; Heidbreder, Anna A; Cochen De Cock, Valérie V; Mollenhauer, Brit B; Sixel-Döring, Friederike F; Trenkwalder, Claudia C; Sonka, Karel K; Kemlink, David D; Figorilli, Michela M; Puligheddu, Monica M; Dijkstra, Femke F; Viaene, Mineke M; Oertel, Wolfang W; Toffoli, Marco M; Gigli, Gian Luigi GL; Valente, Mariarosaria M; Gagnon, Jean-François JF; Nalls, Mike A MA; Singleton, Andrew B AB; , ; Desautels, Alex A; Montplaisir, Jacques Y JY; Cannon, Paul P; Ross, Owen A OA; Boeve, Bradley F BF; Dupré, Nicolas N; Fon, Edward A EA; Postuma, Ronald B RB; Pihlstrøm, Lasse L; Rouleau, Guy A GA; Gan-Or, Ziv Z
The role of myoglobin in epithelial cancers: Insights from transcriptomics.
International Journal Of Molecular Medicine
Bicker, Anne A; Nauth, Theresa T; Gerst, Daniela D; Aboouf, Mostafa Ahmed MA; Fandrey, Joachim J; Kristiansen, Glen G; Gorr, Thomas Alexander TA; Hankeln, Thomas T