Weak Association Between Genetic Markers of Hyperuricemia and Cardiorenal Outcomes: Insights From the STANISLAS Study Cohort With a 20-Year Follow-Up.
Journal Of The American Heart Association
Kanbay, Mehmet M; Xhaard, Constance C; Le Floch, Edith E; Dandine-Roulland, Claire C; Girerd, Nicolas N; Ferreira, João Pedro JP; Boivin, Jean-Marc JM; Wagner, Sandra S; Bacq-Daian, Delphine D; Deleuze, Jean-François JF; Zannad, Faiez F; Rossignol, Patrick P
Fine mapping and identification of serum urate loci in American Indians: The Strong Heart Family Study.
Scientific Reports
Chittoor, Geetha G; Haack, Karin K; Balakrishnan, Poojitha P; Bizon, Christopher C; Laston, Sandra S; Best, Lyle G LG; MacCluer, Jean W JW; North, Kari E KE; Umans, Jason G JG; Franceschini, Nora N; Prasad, Gauri G; Macias-Kauffer, Luis L; Villarreal-Molina, Teresa T; Bharadwaj, Dwaipayan D; Canizales-Quinteros, Samuel S; Navas-Acien, Ana A; Cole, Shelley A SA; Voruganti, V S VS
Introducing the first whole genomes of nationals from the United Arab Emirates.
Scientific Reports
AlSafar, Habiba S HS; Al-Ali, Mariam M; Elbait, Gihan Daw GD; Al-Maini, Mustafa H MH; Ruta, Dymitr D; Peramo, Braulio B; Henschel, Andreas A; Tay, Guan K GK
Payer, Lindsay M LM; Steranka, Jared P JP; Ardeljan, Daniel D; Walker, JaNiece J; Fitzgerald, Kathryn C KC; Calabresi, Peter A PA; Cooper, Thomas A TA; Burns, Kathleen H KH
Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studies.
Bmj (Clinical Research Ed.)
Li, Xue X; Meng, Xiangrui X; Timofeeva, Maria M; Tzoulaki, Ioanna I; Tsilidis, Konstantinos K KK; Ioannidis, John PA JP; Campbell, Harry H; Theodoratou, Evropi E
Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
Genome Medicine
Nagy, Reka R; Boutin, Thibaud S TS; Marten, Jonathan J; Huffman, Jennifer E JE; Kerr, Shona M SM; Campbell, Archie A; Evenden, Louise L; Gibson, Jude J; Amador, Carmen C; Howard, David M DM; Navarro, Pau P; Morris, Andrew A; Deary, Ian J IJ; Hocking, Lynne J LJ; Padmanabhan, Sandosh S; Smith, Blair H BH; Joshi, Peter P; Wilson, James F JF; Hastie, Nicholas D ND; Wright, Alan F AF; McIntosh, Andrew M AM; Porteous, David J DJ; Haley, Chris S CS; Vitart, Veronique V; Hayward, Caroline C
Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling.
Clinical Kidney Journal
Bhatnagar, Vibha V; Richard, Erin L EL; Wu, Wei W; Nievergelt, Caroline M CM; Lipkowitz, Michael S MS; Jeff, Janina J; Maihofer, Adam X AX; Nigam, Sanjay K SK
Genetics of kidney disease and related cardiometabolic phenotypes in Zuni Indians: the Zuni Kidney Project.
Frontiers In Genetics
Laston, Sandra L SL; Voruganti, V Saroja VS; Haack, Karin K; Shah, Vallabh O VO; Bobelu, Arlene A; Bobelu, Jeanette J; Ghahate, Donica D; Harford, Antonia M AM; Paine, Susan S SS; Tentori, Francesca F; Cole, Shelley A SA; MacCluer, Jean W JW; Comuzzie, Anthony G AG; Zager, Philip G PG
Four pairs of gene-gene interactions associated with increased risk for type 2 diabetes (CDKN2BAS-KCNJ11), obesity (SLC2A9-IGF2BP2, FTO-APOA5), and hypertension (MC4R-IGF2BP2) in Chinese women.
Meta Gene
Wang, M H MH; Li, J J; Yeung, V S Y VS; Zee, B C Y BC; Yu, R H Y RH; Ho, S S; Waye, M M Y MM
Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrations.
Bmc Genetics
Scharpf, Robert B RB; Mireles, Lynn L; Yang, Qiong Q; Köttgen, Anna A; Ruczinski, Ingo I; Susztak, Katalin K; Halper-Stromberg, Eitan E; Tin, Adrienne A; Cristiano, Stephen S; Chakravarti, Aravinda A; Boerwinkle, Eric E; Fox, Caroline S CS; Coresh, Josef J; Linda Kao, Wen Hong WH
Genome-wide association analysis confirms and extends the association of SLC2A9 with serum uric acid levels to Mexican Americans.
Frontiers In Genetics
Voruganti, Venkata Saroja VS; Kent, Jack W JW; Debnath, Subrata S; Cole, Shelley A SA; Haack, Karin K; Göring, Harald H H HH; Carless, Melanie A MA; Curran, Joanne E JE; Johnson, Matthew P MP; Almasy, Laura L; Dyer, Thomas D TD; Maccluer, Jean W JW; Moses, Eric K EK; Abboud, Hanna E HE; Mahaney, Michael C MC; Blangero, John J; Comuzzie, Anthony G AG
Replication of the effect of SLC2A9 genetic variation on serum uric acid levels in American Indians.
European Journal Of Human Genetics : Ejhg
Voruganti, V Saroja VS; Franceschini, Nora N; Haack, Karin K; Laston, Sandra S; MacCluer, Jean W JW; Umans, Jason G JG; Comuzzie, Anthony G AG; North, Kari E KE; Cole, Shelley A SA
A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls.
Obesity (Silver Spring, Md.)
Li, Wei-Dong WD; Jiao, Hongxiao H; Wang, Kai K; Zhang, Clarence K CK; Glessner, Joseph T JT; Grant, Struan F A SF; Zhao, Hongyu H; Hakonarson, Hakon H; Arlen Price, R R
Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates.
Plos One
Wei, Wenhua W; Hemani, Gibran G; Hicks, Andrew A AA; Vitart, Veronique V; Cabrera-Cardenas, Claudia C; Navarro, Pau P; Huffman, Jennifer J; Hayward, Caroline C; Knott, Sara A SA; Rudan, Igor I; Pramstaller, Peter P PP; Wild, Sarah H SH; Wilson, James F JF; Campbell, Harry H; Dunlop, Malcolm G MG; Hastie, Nicholas N; Wright, Alan F AF; Haley, Chris S CS
Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.
Human Molecular Genetics
Tin, Adrienne A; Woodward, Owen M OM; Kao, Wen Hong Linda WH; Liu, Ching-Ti CT; Lu, Xiaoning X; Nalls, Michael A MA; Shriner, Daniel D; Semmo, Mariam M; Akylbekova, Ermeg L EL; Wyatt, Sharon B SB; Hwang, Shih-Jen SJ; Yang, Qiong Q; Zonderman, Alan B AB; Adeyemo, Adebowale A AA; Palmer, Cameron C; Meng, Yan Y; Reilly, Muredach M; Shlipak, Michael G MG; Siscovick, David D; Evans, Michele K MK; Rotimi, Charles N CN; Flessner, Michael F MF; Köttgen, Michael M; Cupples, L Adrienne LA; Fox, Caroline S CS; Köttgen, Anna A; ,
A genome-wide association study of serum uric acid in African Americans.
Bmc Medical Genomics
Charles, Bashira A BA; Shriner, Daniel D; Doumatey, Ayo A; Chen, Guanjie G; Zhou, Jie J; Huang, Hanxia H; Herbert, Alan A; Gerry, Norman P NP; Christman, Michael F MF; Adeyemo, Adebowale A; Rotimi, Charles N CN
Genome-wide scan identifies a quantitative trait locus at 4p15.3 for serum urate.
European Journal Of Human Genetics : Ejhg
Cummings, Nik N; Dyer, Thomas D TD; Kotea, Navaratnam N; Kowlessur, Sudhir S; Chitson, Pierrot P; Zimmet, Paul P; Blangero, John J; Jowett, Jeremy B M JB
Bayesian methods for instrumental variable analysis with genetic instruments ('Mendelian randomization'): example with urate transporter SLC2A9 as an instrumental variable for effect of urate levels on metabolic syndrome.
International Journal Of Epidemiology
McKeigue, Paul M PM; Campbell, Harry H; Wild, Sarah S; Vitart, Veronique V; Hayward, Caroline C; Rudan, Igor I; Wright, Alan F AF; Wilson, James F JF
Sex and age interaction with genetic association of atherogenic uric acid concentrations.
Atherosclerosis
Brandstätter, Anita A; Lamina, Claudia C; Kiechl, Stefan S; Hunt, Steven C SC; Coassin, Stefan S; Paulweber, Bernhard B; Kramer, Felix F; Summerer, Monika M; Willeit, Johann J; Kedenko, Lyudmyla L; Adams, Ted D TD; Kronenberg, Florian F
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.
Lancet (London, England)
Dehghan, Abbas A; Köttgen, Anna A; Yang, Qiong Q; Hwang, Shih-Jen SJ; Kao, Wh Linda WL; Rivadeneira, Fernando F; Boerwinkle, Eric E; Levy, Daniel D; Hofman, Albert A; Astor, Brad C BC; Benjamin, Emelia J EJ; van Duijn, Cornelia M CM; Witteman, Jacqueline C JC; Coresh, Josef J; Fox, Caroline S CS
Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI.
Diabetes Care
Brandstätter, Anita A; Kiechl, Stefan S; Kollerits, Barbara B; Hunt, Steven C SC; Heid, Iris M IM; Coassin, Stefan S; Willeit, Johann J; Adams, Ted D TD; Illig, Thomas T; Hopkins, Paul N PN; Kronenberg, Florian F
Association of common polymorphisms in GLUT9 gene with gout but not with coronary artery disease in a large case-control study.
Plos One
Stark, Klaus K; Reinhard, Wibke W; Neureuther, Katharina K; Wiedmann, Silke S; Sedlacek, Kamil K; Baessler, Andrea A; Fischer, Marcus M; Weber, Stefan S; Kaess, Bernhard B; Erdmann, Jeanette J; Schunkert, Heribert H; Hengstenberg, Christian C
Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.
American Journal Of Human Genetics
Wallace, Chris C; Newhouse, Stephen J SJ; Braund, Peter P; Zhang, Feng F; Tobin, Martin M; Falchi, Mario M; Ahmadi, Kourosh K; Dobson, Richard J RJ; Marçano, Ana Carolina B AC; Hajat, Cother C; Burton, Paul P; Deloukas, Panagiotis P; Brown, Morris M; Connell, John M JM; Dominiczak, Anna A; Lathrop, G Mark GM; Webster, John J; Farrall, Martin M; Spector, Tim T; Samani, Nilesh J NJ; Caulfield, Mark J MJ; Munroe, Patricia B PB