APC c.64_65delinsGC ;(p.N22A)

Variant ID: 5-112090651-AA-GC

NM_000038.5(APC):c.64_65delinsGC;(p.N22A)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


High-resolution structure of the amino acid transporter AdiC reveals insights into the role of water molecules and networks in oligomerization and substrate binding.

Bmc Biology
Ilgü, Hüseyin H; Jeckelmann, Jean-Marc JM; Kalbermatter, David D; Ucurum, Zöhre Z; Lemmin, Thomas T; Fotiadis, Dimitrios D
Publication Date: 2021-08-30

Variant appearance in text: APC: N22A
PubMed Link: 34461897
Variant Present in the following documents:
  • Main text
  • 12915_2021_Article_1102.pdf
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Rush Hour of LATs towards Their Transport Cycle.

Membranes
Nicolàs-Aragó, Adrià A; Fort, Joana J; Palacín, Manuel M; Errasti-Murugarren, Ekaitz E
Publication Date: 2021-08-08

Variant appearance in text: APC: N22A
PubMed Link: 34436365
Variant Present in the following documents:
  • Main text
  • membranes-11-00602.pdf
View BVdb publication page



Asc-1 Transporter (SLC7A10): Homology Models And Molecular Dynamics Insights Into The First Steps Of The Transport Mechanism.

Scientific Reports
Mikou, Afaf A; Cabayé, Alexandre A; Goupil, Anne A; Bertrand, Hugues-Olivier HO; Mothet, Jean-Pierre JP; Acher, Francine C FC
Publication Date: 2020-02-28

Variant appearance in text: APC: N22A
PubMed Link: 32111919
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_60617.pdf
View BVdb publication page



Effects of Mutations and Ligands on the Thermostability of the l-Arginine/Agmatine Antiporter AdiC and Deduced Insights into Ligand-Binding of Human l-Type Amino Acid Transporters.

International Journal Of Molecular Sciences
Ilgü, Hüseyin H; Jeckelmann, Jean-Marc JM; Colas, Claire C; Ucurum, Zöhre Z; Schlessinger, Avner A; Fotiadis, Dimitrios D
Publication Date: 2018-03-20

Variant appearance in text: APC: N22A
PubMed Link: 29558430
Variant Present in the following documents:
  • Main text
  • ijms-19-00918.pdf
View BVdb publication page



Insights into the molecular basis for substrate binding and specificity of the wild-type L-arginine/agmatine antiporter AdiC.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Ilgü, Hüseyin H; Jeckelmann, Jean-Marc JM; Gapsys, Vytautas V; Ucurum, Zöhre Z; de Groot, Bert L BL; Fotiadis, Dimitrios D
Publication Date: 2016-09-13

Variant appearance in text: APC: N22A
PubMed Link: 27582465
Variant Present in the following documents:
  • Main text
View BVdb publication page



Protonation of glutamate 208 induces the release of agmatine in an outward-facing conformation of an arginine/agmatine antiporter.

The Journal Of Biological Chemistry
Zomot, Elia E; Bahar, Ivet I
Publication Date: 2011-06-03

Variant appearance in text: APC: N22A
PubMed Link: 21487006
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular basis of substrate-induced permeation by an amino acid antiporter.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Kowalczyk, Lukasz L; Ratera, Mercè M; Paladino, Antonella A; Bartoccioni, Paola P; Errasti-Murugarren, Ekaitz E; Valencia, Eva E; Portella, Guillem G; Bial, Susanna S; Zorzano, Antonio A; Fita, Ignacio I; Orozco, Modesto M; Carpena, Xavier X; Vázquez-Ibar, José Luis JL; Palacín, Manuel M
Publication Date: 2011-03-08

Variant appearance in text: APC: N22A
PubMed Link: 21368142
Variant Present in the following documents:
  • Main text
View BVdb publication page