The two SAMP repeats and their phosphorylation state in Drosophila Adenomatous polyposis coli-2 play mechanistically distinct roles in negatively regulating Wnt signaling.
Molecular Biology Of The Cell
Kunttas-Tatli, Ezgi E; Von Kleeck, Ryan A RA; Greaves, Bradford D BD; Vinson, David D; Roberts, David M DM; McCartney, Brooke M BM
FOXKs promote Wnt/β-catenin signaling by translocating DVL into the nucleus.
Developmental Cell
Wang, Wenqi W; Li, Xu X; Lee, Moonsup M; Jun, Sohee S; Aziz, Kathryn E KE; Feng, Lin L; Tran, My Kim MK; Li, Nan N; McCrea, Pierre D PD; Park, Jae-Il JI; Chen, Junjie J
Restriction of intestinal stem cell expansion and the regenerative response by YAP.
Nature
Barry, Evan R ER; Morikawa, Teppei T; Butler, Brian L BL; Shrestha, Kriti K; de la Rosa, Rosemarie R; Yan, Kelley S KS; Fuchs, Charles S CS; Magness, Scott T ST; Smits, Ron R; Ogino, Shuji S; Kuo, Calvin J CJ; Camargo, Fernando D FD