APC c.463A>G ;(p.K155E)

Variant ID: 5-112111366-A-G

NM_000038.5(APC):c.463A>G;(p.K155E)

This variant was identified in 9 publications

View GRCh38 version.




Publications:


Protein S K196E mutation reduces its cofactor activity for APC but not for TFPI.

Research And Practice In Thrombosis And Haemostasis
Maruyama, Keiko K; Akiyama, Masashi M; Miyata, Toshiyuki T; Kokame, Koichi K
Publication Date: 2018-10

Variant appearance in text: APC: K155E
PubMed Link: 30349894
Variant Present in the following documents:
  • Main text
  • RTH2-2-751.pdf
View BVdb publication page



Deficiencies of the Natural Anticoagulants - Novel Clinical Laboratory Aspects of Thrombophilia Testing.

Ejifcc
Bereczky, Zsuzsanna Z; Gindele, Réka R; Speker, Marianna M; Kállai, Judit J
Publication Date: 2016-04

Variant appearance in text: APC: Lys155Glu
PubMed Link: 27683526
Variant Present in the following documents:
  • Main text
  • ejifcc-27-130.pdf
View BVdb publication page



Exacerbated venous thromboembolism in mice carrying a protein S K196E mutation.

Blood
Banno, Fumiaki F; Kita, Toshiyuki T; Fernández, José A JA; Yanamoto, Hiroji H; Tashima, Yuko Y; Kokame, Koichi K; Griffin, John H JH; Miyata, Toshiyuki T
Publication Date: 2015-11-05

Variant appearance in text: APC: K155E
PubMed Link: 26251307
Variant Present in the following documents:
  • Main text
View BVdb publication page



Plasma protein S residues 37-50 mediate its binding to factor Va and inhibition of blood coagulation.

Thrombosis And Haemostasis
Heeb, Mary J MJ; Mesters, Rolf M RM; Fernández, José A JA; Hackeng, Tilman M TM; Nakasone, Ryon K RK; Griffin, John H JH
Publication Date: 2013-08

Variant appearance in text: APC: K155E
PubMed Link: 23892573
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetically determined ABCB5 functionality correlates with pigmentation phenotype and melanoma risk.

Biochemical And Biophysical Research Communications
Lin, Jennifer Y JY; Zhang, Mingfeng M; Schatton, Tobias T; Wilson, Brian J BJ; Alloo, Allireza A; Ma, Jie J; Qureshi, Abrar A AA; Frank, Natasha Y NY; Han, Jiali J; Frank, Markus H MH
Publication Date: 2013-07-05

Variant appearance in text: APC: K155E
PubMed Link: 23770371
Variant Present in the following documents:
  • Main text
View BVdb publication page



Activated protein C anticoagulant system dysfunction and thrombophilia in Asia.

Annals Of Laboratory Medicine
Hamasaki, Naotaka N; Kuma, Hiroyuki H; Tsuda, Hiroko H
Publication Date: 2013-01

Variant appearance in text: APC: K155E
PubMed Link: 23301217
Variant Present in the following documents:
  • Main text
  • alm-33-8.pdf
View BVdb publication page



Activated protein C cofactor function of protein S: a critical role for Asp95 in the EGF1-like domain.

Blood
Andersson, Helena M HM; Arantes, Márcia J MJ; Crawley, James T B JT; Luken, Brenda M BM; Tran, Sinh S; Dahlbäck, Björn B; Lane, David A DA; Rezende, Suely M SM
Publication Date: 2010-06-10

Variant appearance in text: APC: K155E
PubMed Link: 20308596
Variant Present in the following documents:
  • Main text
View BVdb publication page



Role of the PROS1 gene in thrombosis: lessons and controversies.

Expert Review Of Hematology
Heeb, Mary J MJ
Publication Date: 2008-10

Variant appearance in text: APC: Lys155Glu
PubMed Link: 19809585
Variant Present in the following documents:
  • Main text
View BVdb publication page



15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Yan, Min M; Rerko, Ronald M RM; Platzer, Petra P; Dawson, Dawn D; Willis, Joseph J; Tong, Min M; Lawrence, Earl E; Lutterbaugh, James J; Lu, Shilong S; Willson, James K V JK; Luo, Guangbin G; Hensold, Jack J; Tai, Hsin-Hsiung HH; Wilson, Keith K; Markowitz, Sanford D SD
Publication Date: 2004-12-14

Variant appearance in text: APC: K155E
PubMed Link: 15574495
Variant Present in the following documents:
  • Main text
View BVdb publication page