Publications:

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Structure of the core human NADPH oxidase NOX2.

Nature Communications

Noreng, Sigrid S; Ota, Naruhisa N; Sun, Yonglian Y; Ho, Hoangdung H; Johnson, Matthew M; Arthur, Christopher P CP; Schneider, Kellen K; Lehoux, Isabelle I; Davies, Christopher W CW; Mortara, Kyle K; Wong, Kit K; Seshasayee, Dhaya D; Masureel, Matthieu M; Payandeh, Jian J; Yi, Tangsheng T; Koerber, James T JT

Publication Date: 2022-10-14

Variant appearance in text: APC: L234A

PubMed Link: 36241643

Variant Present in the following documents:

• Main text
• 41467_2022_Article_33711.pdf

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Distinct immune stimulatory effects of anti-human VISTA antibodies are determined by Fc-receptor interaction.

Frontiers In Immunology

Mostböck, Sven S; Wu, Helen Haixia HH; Fenn, Timothy T; Riegler, Bettina B; Strahlhofer, Susanne S; Huang, Yining Y; Hansen, Gale G; Kroe-Barrett, Rachel R; Tirapu, Iñigo I; Vogt, Anne B AB

Publication Date: 2022

Variant appearance in text: APC: L234A

PubMed Link: 35967294

Variant Present in the following documents:

• Main text
• fimmu-13-862757.pdf

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A TCR mimic monoclonal antibody reactive with the "public" phospho-neoantigen pIRS2/HLA-A*02:01 complex.

Jci Insight

Dao, Tao T; Mun, Sung Soo SS; Molvi, Zaki Z; Korontsvit, Tatyana T; Klatt, Martin G MG; Khan, Abdul G AG; Nyakatura, Elisabeth K EK; Pohl, Mary Ann MA; White, Thomas E TE; Balderes, Paul J PJ; Lorenz, Ivo C IC; O'Reilly, Richard J RJ; Scheinberg, David A DA

Publication Date: 2022-03-08

Variant appearance in text: APC: L234A

PubMed Link: 35260532

Variant Present in the following documents:

• jciinsight-7-151624.pdf

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Fc-engineered antibodies with immune effector functions completely abolished.

Plos One

Wilkinson, Ian I; Anderson, Stephen S; Fry, Jeremy J; Julien, Louis Alex LA; Neville, David D; Qureshi, Omar O; Watts, Gary G; Hale, Geoff G

Publication Date: 2021

Variant appearance in text: APC: L234A

PubMed Link: 34932587

Variant Present in the following documents:

• pone.0260954.pdf

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Fc-engineered antibodies with immune effector functions completely abolished.

Plos One

Wilkinson, Ian I; Anderson, Stephen S; Fry, Jeremy J; Julien, Louis Alex LA; Neville, David D; Qureshi, Omar O; Watts, Gary G; Hale, Geoff G

Publication Date: 2021

Variant appearance in text: APC: L234A

PubMed Link: 34932587

Variant Present in the following documents:

• pone.0260954.pdf

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The Role of Fc Receptors on the Effectiveness of Therapeutic Monoclonal Antibodies.

International Journal Of Molecular Sciences

Gogesch, Patricia P; Dudek, Simone S; van Zandbergen, Ger G; Waibler, Zoe Z; Anzaghe, Martina M

Publication Date: 2021-08-19

Variant appearance in text: APC: L234A

PubMed Link: 34445651

Variant Present in the following documents:

• Main text
• ijms-22-08947.pdf

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Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies.

Elife

Kerns, S Jordan SJ; Belgur, Chaitra C; Petropolis, Debora D; Kanellias, Marianne M; Barrile, Riccardo R; Sam, Johannes J; Weinzierl, Tina T; Fauti, Tanja T; Freimoser-Grundschober, Anne A; Eckmann, Jan J; Hage, Carina C; Geiger, Martina M; Ng, Patrick Ray PR; Tien-Street, William W; Manatakis, Dimitris V DV; Micallef, Virginie V; Gerard, Regine R; Bscheider, Michael M; Breous-Nystrom, Ekaterina E; Schneider, Anneliese A; Giusti, Anna Maria AM; Bertinetti-Lapatki, Cristina C; Grant, Heather Shannon HS; Roth, Adrian B AB; Hamilton, Geraldine A GA; Singer, Thomas T; Karalis, Katia K; Moisan, Annie A; Bruenker, Peter P; Klein, Christian C; Bacac, Marina M; Gjorevski, Nikolce N; Cabon, Lauriane L

Publication Date: 2021-08-11

Variant appearance in text: APC: L234A

PubMed Link: 34378534

Variant Present in the following documents:

• Main text

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PD-L1/LAG-3 bispecific antibody enhances tumor-specific immunity.

Oncoimmunology

Jiang, Haiping H; Ni, Haiqing H; Zhang, Pan P; Guo, Xiaoli X; Wu, Min M; Shen, Haoran H; Wang, Jie J; Wu, Weiwei W; Wu, Zhihai Z; Ding, Jiazheng J; Tang, Rong R; Zhou, Shuaixiang S; Chen, Bingliang B; Yu, Michael M; Jing, Hua H; Liu, Junjian J

Publication Date: 2021

Variant appearance in text: APC: L234A

PubMed Link: 34239776

Variant Present in the following documents:

• Main text
• KONI_10_1943180.pdf

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VISTA is an activating receptor in human monocytes.

The Journal Of Experimental Medicine

Rogers, Bryan M BM; Smith, Laura L; Dezso, Zoltan Z; Shi, Xu X; DiGiammarino, Enrico E; Nguyen, Denny D; Sethuraman, Sunantha S; Zheng, Pingping P; Choi, Donghee D; Zhang, Dong D; Nguyen, Andrew A; McGuire, Kathleen K; Liu, Wei W; Chung, Namjin N; Chao, Debra T DT; Ye, Shiming S; Starbeck-Miller, Gabriel R GR

Publication Date: 2021-08-02

Variant appearance in text: APC: L234A

PubMed Link: 34106206

Variant Present in the following documents:

• Main text

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Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection.

Cell

Winkler, Emma S ES; Gilchuk, Pavlo P; Yu, Jinsheng J; Bailey, Adam L AL; Chen, Rita E RE; Chong, Zhenlu Z; Zost, Seth J SJ; Jang, Hyesun H; Huang, Ying Y; Allen, James D JD; Case, James Brett JB; Sutton, Rachel E RE; Carnahan, Robert H RH; Darling, Tamarand L TL; Boon, Adrianus C M ACM; Mack, Matthias M; Head, Richard D RD; Ross, Ted M TM; Crowe, James E JE; Diamond, Michael S MS

Publication Date: 2021-04-01

Variant appearance in text: APC: L234A

PubMed Link: 33691139

Variant Present in the following documents:

• Main text

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Fusion of Bacterial Flagellin to a Dendritic Cell-Targeting αCD40 Antibody Construct Coupled With Viral or Leukemia-Specific Antigens Enhances Dendritic Cell Maturation and Activates Peptide-Responsive T Cells.

Frontiers In Immunology

Schmitt, Saskia S; Tahk, Siret S; Lohner, Alina A; Hänel, Gerulf G; Maiser, Andreas A; Hauke, Martina M; Patel, Lubna L; Rothe, Maurine M; Josenhans, Christine C; Leonhardt, Heinrich H; Griffioen, Marieke M; Deiser, Katrin K; Fenn, Nadja C NC; Hopfner, Karl-Peter KP; Subklewe, Marion M

Publication Date: 2020

Variant appearance in text: APC: L234A

PubMed Link: 33281829

Variant Present in the following documents:

• Main text
• fimmu-11-602802.pdf

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Fc-Engineering for Modulated Effector Functions-Improving Antibodies for Cancer Treatment.

Antibodies (Basel, Switzerland)

Liu, Rena R; Oldham, Robert J RJ; Teal, Emma E; Beers, Stephen A SA; Cragg, Mark S MS

Publication Date: 2020-11-17

Variant appearance in text: APC: L234A

PubMed Link: 33212886

Variant Present in the following documents:

• antibodies-09-00064.pdf

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ARGX-117, a therapeutic complement inhibiting antibody targeting C2.

The Journal Of Allergy And Clinical Immunology

Van de Walle, Inge I; Silence, Karen K; Budding, Kevin K; Van de Ven, Liesbeth L; Dijkxhoorn, Kim K; de Zeeuw, Elisabeth E; Yildiz, Cafer C; Gabriels, Sofie S; Percier, Jean-Michel JM; Wildemann, Johanna J; Meeldijk, Jan J; Simons, Peter J PJ; Boon, Louis L; Cox, Linda L; Holgate, Rob R; Urbanus, Rolf R; Otten, Henny G HG; Leusen, Jeanette H W JHW; Blanchetot, Christophe C; de Haard, Hans H; Hack, C Erik CE; Boross, Peter P

Publication Date: 2021-04

Variant appearance in text: APC: L234A

PubMed Link: 32926878

Variant Present in the following documents:

• Main text

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Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells.

Journal For Immunotherapy Of Cancer

Chen, Heyu H; Chen, Yuanzhi Y; Deng, Mi M; John, Samuel S; Gui, Xun X; Kansagra, Ankit A; Chen, Weina W; Kim, Jaehyup J; Lewis, Cheryl C; Wu, Guojin G; Xie, Jingjing J; Zhang, Lingbo L; Huang, Ryan R; Liu, Xiaoye X; Arase, Hisashi H; Huang, Yang Y; Yu, Hai H; Luo, Wenxin W; Xia, Ningshao N; Zhang, Ningyan N; An, Zhiqiang Z; Zhang, Cheng Cheng CC

Publication Date: 2020-08

Variant appearance in text: APC: L234A

PubMed Link: 32771992

Variant Present in the following documents:

• Main text
• jitc-2019-000515.pdf

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Siglec-15 recognition of sialoglycans on tumor cell lines can occur independently of sialyl Tn antigen expression.

Glycobiology

Murugesan, Gavuthami G; Correia, Viviana G VG; Palma, Angelina S AS; Chai, Wengang W; Li, Chunxia C; Feizi, Ten T; Martin, Eva E; Laux, Brigitte B; Franz, Alexandra A; Fuchs, Klaus K; Weigle, Bernd B; Crocker, Paul R PR

Publication Date: 2021-01-09

Variant appearance in text: APC: L234A

PubMed Link: 32501471

Variant Present in the following documents:

• Main text

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Harnessing the immune system via FcγR function in immune therapy: a pathway to next-gen mAbs.

Immunology And Cell Biology

Chenoweth, Alicia M AM; Wines, Bruce D BD; Anania, Jessica C JC; Mark Hogarth, P P

Publication Date: 2020-04

Variant appearance in text: APC: L234A

PubMed Link: 32157732

Variant Present in the following documents:

• IMCB-9999-na.pdf

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Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor.

Nature Medicine

Dussupt, Vincent V; Sankhala, Rajeshwer S RS; Gromowski, Gregory D GD; Donofrio, Gina G; De La Barrera, Rafael A RA; Larocca, Rafael A RA; Zaky, Weam W; Mendez-Rivera, Letzibeth L; Choe, Misook M; Davidson, Edgar E; McCracken, Michael K MK; Brien, James D JD; Abbink, Peter P; Bai, Hongjun H; Bryan, Aubrey L AL; Bias, Candace Hope CH; Berry, Irina Maljkovic IM; Botero, Nubia N; Cook, Tanya T; Doria-Rose, Nicole A NA; Escuer, Ariadna Grinyo I AGI; Frimpong, Justice Akuoku JA; Geretz, Aviva A; Hernandez, Mayda M; Hollidge, Bradley S BS; Jian, Ningbo N; Kabra, Kareem K; Leggat, David J DJ; Liu, Jinyan J; Pinto, Amelia K AK; Rutvisuttinunt, Wiriya W; Setliff, Ian I; Tran, Ursula U; Townsley, Samantha S; Doranz, Benjamin J BJ; Rolland, Morgane M; McDermott, Adrian B AB; Georgiev, Ivelin S IS; Thomas, Rasmi R; Robb, Merlin L ML; Eckels, Kenneth H KH; Barranco, Elizabeth E; Koren, Michael M; Smith, Darci R DR; Jarman, Richard G RG; George, Sarah L SL; Stephenson, Kathryn E KE; Barouch, Dan H DH; Modjarrad, Kayvon K; Michael, Nelson L NL; Joyce, M Gordon MG; Krebs, Shelly J SJ

Publication Date: 2020-02

Variant appearance in text: APC: L234A

PubMed Link: 32015557

Variant Present in the following documents:

• Main text

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Enhanced SLAMF7 Homotypic Interactions by Elotuzumab Improves NK Cell Killing of Multiple Myeloma.

Cancer Immunology Research

Pazina, Tatiana T; James, Ashley M AM; Colby, Kimberly B KB; Yang, Yibin Y; Gale, Andrew A; Jhatakia, Amy A; Kearney, Alper Y AY; Graziano, Robert F RF; Bezman, Natalie A NA; Robbins, Michael D MD; Cohen, Adam D AD; Campbell, Kerry S KS

Publication Date: 2019-10

Variant appearance in text: APC: L234A

PubMed Link: 31431433

Variant Present in the following documents:

• Main text

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Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein.

Nature Communications

Zhou, Haixia H; Chen, Yingzhu Y; Zhang, Shuyuan S; Niu, Peihua P; Qin, Kun K; Jia, Wenxu W; Huang, Baoying B; Zhang, Senyan S; Lan, Jun J; Zhang, Linqi L; Tan, Wenjie W; Wang, Xinquan X

Publication Date: 2019-07-11

Variant appearance in text: APC: L234A

PubMed Link: 31296843

Variant Present in the following documents:

• Main text

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Influence of the bispecific antibody IgG subclass on T cell redirection.

Mabs

Kapelski, Stephanie S; Cleiren, Erna E; Attar, Ricardo M RM; Philippar, Ulrike U; Häsler, Julien J; Chiu, Mark L ML

Publication Date: 2019

Variant appearance in text: APC: L234A

PubMed Link: 31242061

Variant Present in the following documents:

• Main text

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Safety, Pharmacokinetics, and Pharmacodynamics of Multiple Rising Doses of BI 655064, an Antagonistic Anti-CD40 Antibody, in Healthy Subjects: A Potential Novel Treatment for Autoimmune Diseases.

Journal Of Clinical Pharmacology

Schwabe, Christian C; Rosenstock, Bernd B; Doan, Thi T; Hamilton, Paul P; Dunbar, P Rod PR; Eleftheraki, Anastasia G AG; Joseph, David D; Hilbert, James J; Schoelch, Corinna C; Padula, Steven J SJ; Steffgen, Jürgen J

Publication Date: 2018-12

Variant appearance in text: APC: Leu234Ala

PubMed Link: 30113724

Variant Present in the following documents:

• Main text
• JCPH-58-1566.pdf

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Safety, pharmacokinetics and pharmacodynamics of single rising doses of BI 655064, an antagonistic anti-CD40 antibody in healthy subjects: a potential novel treatment for autoimmune diseases.

European Journal Of Clinical Pharmacology

Albach, Fredrik N FN; Wagner, Frank F; Hüser, Andreas A; Igel, Julia J; Joseph, David D; Hilbert, James J; Schoelch, Corinna C; Padula, Steven J SJ; Steffgen, Jürgen J

Publication Date: 2018-02

Variant appearance in text: APC: Leu234Ala

PubMed Link: 29127458

Variant Present in the following documents:

• Main text
• 228_2017_Article_2362.pdf

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Strain-transcending Fc-dependent killing of Plasmodium falciparum by merozoite surface protein 2 allele-specific human antibodies.

Infection And Immunity

Stubbs, Janine J; Olugbile, Sope S; Saidou, Balam B; Simpore, Jacques J; Corradin, Giampietro G; Lanzavecchia, Antonio A

Publication Date: 2011-03

Variant appearance in text: APC: L234A

PubMed Link: 21189324

Variant Present in the following documents:

• Main text

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Secretory phospholipase A2-IID is an effector molecule of CD4+CD25+ regulatory T cells.

Proceedings Of The National Academy Of Sciences Of The United States Of America

von Allmen, Caroline E CE; Schmitz, Nicole N; Bauer, Monika M; Hinton, Heather J HJ; Kurrer, Michael O MO; Buser, Regula B RB; Gwerder, Myriam M; Muntwiler, Simone S; Sparwasser, Tim T; Beerli, Roger R RR; Bachmann, Martin F MF

Publication Date: 2009-07-14

Variant appearance in text: APC: L234A

PubMed Link: 19564598

Variant Present in the following documents:

• Main text

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