Publications:

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Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture, phosphorylation, and ubiquitylation.

Molecular Cell

Ranes, Michael M; Zaleska, Mariola M; Sakalas, Saira S; Knight, Ruth R; Guettler, Sebastian S

Publication Date: 2021-08-19

Variant appearance in text: APC: S811*

PubMed Link: 34352208

Variant Present in the following documents:

• mmc1.pdf
• mmc3.pdf

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Establishment and characterization of a new human colon cancer cell line, PUMC-CRC1.

Scientific Reports

Bian, Xiaocui X; Cao, Fang F; Wang, Xiaowan X; Hou, Yuhong Y; Zhao, Haitao H; Liu, Yuqin Y

Publication Date: 2021-06-23

Variant appearance in text: APC: S811*

PubMed Link: 34162944

Variant Present in the following documents:

• Main text
• 41598_2021_Article_92491.pdf

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Direct targeting of oncogenic RAS mutants with a tumor-specific cytosol-penetrating antibody inhibits RAS mutant-driven tumor growth.

Science Advances

Shin, Seung-Min SM; Kim, Ji-Sun JS; Park, Seong-Wook SW; Jun, Sei-Yong SY; Kweon, Hye-Jin HJ; Choi, Dong-Ki DK; Lee, Dakeun D; Cho, Yong Beom YB; Kim, Yong-Sung YS

Publication Date: 2020-01

Variant appearance in text: APC: S811*

PubMed Link: 31998840

Variant Present in the following documents:

• aay2174_SM.pdf

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Mutation Profiling of Premalignant Colorectal Neoplasia.

Gastroenterology Research And Practice

Karczmarski, Jakub J; Goryca, Krzysztof K; Pachlewski, Jacek J; Dabrowska, Michalina M; Pysniak, Kazimiera K; Paziewska, Agnieszka A; Kulecka, Maria M; Lenarcik, Malgorzata M; Mroz, Andrzej A; Mikula, Michal M; Ostrowski, Jerzy J

Publication Date: 2019

Variant appearance in text: APC: S811X

PubMed Link: 31781186

Variant Present in the following documents:

• 2542640.f1.xlsx, sheet 1

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Analysis of resistance mechanisms to abivertinib, a third-generation EGFR tyrosine kinase inhibitor, in patients with EGFR T790M-positive non-small cell lung cancer from a phase I trial.

Ebiomedicine

Zhang, Yi-Chen YC; Chen, Zhi-Hong ZH; Zhang, Xu-Chao XC; Xu, Chong-Rui CR; Yan, Hong-Hong HH; Xie, Zhi Z; Chuai, Shao-Kun SK; Ye, Jun-Yi JY; Han-Zhang, Han H; Zhang, Zhou Z; Bai, Xiao-Yan XY; Su, Jian J; Gan, Bin B; Yang, Jin-Ji JJ; Li, Wen-Feng WF; Tang, Wei W; Luo, Feng Roger FR; Xu, Xiao X; Wu, Yi-Long YL; Zhou, Qing Q

Publication Date: 2019-05

Variant appearance in text: APC: S811*

PubMed Link: 31027916

Variant Present in the following documents:

• Main text

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Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures.

Plos Genetics

Schumacher, Dirk D; Andrieux, Geoffroy G; Boehnke, Karsten K; Keil, Marlen M; Silvestri, Alessandra A; Silvestrov, Maxine M; Keilholz, Ulrich U; Haybaeck, Johannes J; Erdmann, Gerrit G; Sachse, Christoph C; Templin, Markus M; Hoffmann, Jens J; Boerries, Melanie M; Schäfer, Reinhold R; Regenbrecht, Christian R A CRA

Publication Date: 2019-03

Variant appearance in text: APC: S811X

PubMed Link: 30925167

Variant Present in the following documents:

• pgen.1008076.s018.xlsx, sheet 1

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A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors.

Scientific Reports

Menon, Malini M; Elliott, Richard R; Bowers, Leandra L; Balan, Nicolae N; Rafiq, Rumana R; Costa-Cabral, Sara S; Munkonge, Felix F; Trinidade, Ines I; Porter, Roderick R; Campbell, Andrew D AD; Johnson, Emma R ER; Esdar, Christina C; Buchstaller, Hans-Peter HP; Leuthner, Birgitta B; Rohdich, Felix F; Schneider, Richard R; Sansom, Owen O; Wienke, Dirk D; Ashworth, Alan A; Lord, Christopher J CJ

Publication Date: 2019-01-17

Variant appearance in text: APC: S811*

PubMed Link: 30655555

Variant Present in the following documents:

• Main text
• 41598_2018_Article_36447.pdf

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Downregulation of dual-specificity phosphatase 4 enhances cell proliferation and invasiveness in colorectal carcinomas.

Cancer Science

Ichimanda, Michihiro M; Hijiya, Naoki N; Tsukamoto, Yoshiyuki Y; Uchida, Tomohisa T; Nakada, Chisato C; Akagi, Tomonori T; Etoh, Tsuyoshi T; Iha, Hidekatsu H; Inomata, Masafumi M; Takekawa, Mutsuhiro M; Moriyama, Masatsugu M

Publication Date: 2018-01

Variant appearance in text: APC: S811*

PubMed Link: 29150975

Variant Present in the following documents:

• CAS-109-250.pdf

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Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

Nature Communications

Schütte, Moritz M; Risch, Thomas T; Abdavi-Azar, Nilofar N; Boehnke, Karsten K; Schumacher, Dirk D; Keil, Marlen M; Yildiriman, Reha R; Jandrasits, Christine C; Borodina, Tatiana T; Amstislavskiy, Vyacheslav V; Worth, Catherine L CL; Schweiger, Caroline C; Liebs, Sandra S; Lange, Martin M; Warnatz, Hans-Jörg HJ; Butcher, Lee M LM; Barrett, James E JE; Sultan, Marc M; Wierling, Christoph C; Golob-Schwarzl, Nicole N; Lax, Sigurd S; Uranitsch, Stefan S; Becker, Michael M; Welte, Yvonne Y; Regan, Joseph Lewis JL; Silvestrov, Maxine M; Kehler, Inge I; Fusi, Alberto A; Kessler, Thomas T; Herwig, Ralf R; Landegren, Ulf U; Wienke, Dirk D; Nilsson, Mats M; Velasco, Juan A JA; Garin-Chesa, Pilar P; Reinhard, Christoph C; Beck, Stephan S; Schäfer, Reinhold R; Regenbrecht, Christian R A CR; Henderson, David D; Lange, Bodo B; Haybaeck, Johannes J; Keilholz, Ulrich U; Hoffmann, Jens J; Lehrach, Hans H; Yaspo, Marie-Laure ML

Publication Date: 2017-02-10

Variant appearance in text: APC: S811X

PubMed Link: 28186126

Variant Present in the following documents:

• ncomms14262-s5.xlsx, sheet 2

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New trends in aminoglycosides use.

Medchemcomm

Fosso, Marina Y MY; Li, Yijia Y; Garneau-Tsodikova, Sylvie S

Publication Date: 2014-08-01

Variant appearance in text: APC: S811X

PubMed Link: 25071928

Variant Present in the following documents:

• Main text

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Readthrough of premature termination codons in the adenomatous polyposis coli gene restores its biological activity in human cancer cells.

Plos One

Floquet, Célia C; Rousset, Jean-Pierre JP; Bidou, Laure L

Publication Date: 2011

Variant appearance in text: APC: S811X

PubMed Link: 21909382

Variant Present in the following documents:

• Main text
• pone.0024125.pdf

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