Cell-free Lactiplantibacillus plantarum OC01 supernatant suppresses IL-6-induced proliferation and invasion of human colorectal cancer cells: Effect on β-Catenin degradation and induction of autophagy.
Journal Of Traditional And Complementary Medicine
Vallino, Letizia L; Garavaglia, Beatrice B; Visciglia, Annalisa A; Amoruso, Angela A; Pane, Marco M; Ferraresi, Alessandra A; Isidoro, Ciro C
The Wnt Pathway Inhibitor RXC004 Blocks Tumor Growth and Reverses Immune Evasion in Wnt Ligand-dependent Cancer Models.
Cancer Research Communications
Phillips, Caroline C; Bhamra, Inder I; Eagle, Catherine C; Flanagan, Eimear E; Armer, Richard R; Jones, Clifford D CD; Bingham, Matilda M; Calcraft, Peter P; Edmenson Cook, Alicia A; Thompson, Ben B; Woodcock, Simon A SA
The neuronal protein Neuroligin 1 promotes colorectal cancer progression by modulating the APC/β-catenin pathway.
Journal Of Experimental & Clinical Cancer Research : Cr
Pergolizzi, Margherita M; Bizzozero, Laura L; Maione, Federica F; Maldi, Elena E; Isella, Claudio C; Macagno, Marco M; Mariella, Elisa E; Bardelli, Alberto A; Medico, Enzo E; Marchiò, Caterina C; Serini, Guido G; Di Nicolantonio, Federica F; Bussolino, Federico F; Arese, Marco M
Rearrangement-mediated cis-regulatory alterations in advanced patient tumors reveal interactions with therapy.
Cell Reports
Zhang, Yiqun Y; Chen, Fengju F; Pleasance, Erin E; Williamson, Laura L; Grisdale, Cameron J CJ; Titmuss, Emma E; Laskin, Janessa J; Jones, Steven J M SJM; Cortes-Ciriano, Isidro I; Marra, Marco A MA; Creighton, Chad J CJ
A next-generation sequencing-based strategy combining microsatellite instability and tumor mutation burden for comprehensive molecular diagnosis of advanced colorectal cancer.
False-negative errors in next-generation sequencing contribute substantially to inconsistency of mutation databases.
Plos One
Kim, Young-Ho YH; Song, Yura Y; Kim, Jong-Kwang JK; Kim, Tae-Min TM; Sim, Hye Won HW; Kim, Hyung-Lae HL; Jang, Hyonchol H; Kim, Young-Woo YW; Hong, Kyeong-Man KM
Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas.
Cell Death & Disease
De Bessa, Tiphany Coralie TC; Pagano, Alessandra A; Moretti, Ana Iochabel Soares AIS; Oliveira, Percillia Victoria Santos PVS; Mendonça, Samir Andrade SA; Kovacic, Herve H; Laurindo, Francisco Rafael Martins FRM
Genetic and transcriptional evolution alters cancer cell line drug response.
Nature
Ben-David, Uri U; Siranosian, Benjamin B; Ha, Gavin G; Tang, Helen H; Oren, Yaara Y; Hinohara, Kunihiko K; Strathdee, Craig A CA; Dempster, Joshua J; Lyons, Nicholas J NJ; Burns, Robert R; Nag, Anwesha A; Kugener, Guillaume G; Cimini, Beth B; Tsvetkov, Peter P; Maruvka, Yosef E YE; O'Rourke, Ryan R; Garrity, Anthony A; Tubelli, Andrew A AA; Bandopadhayay, Pratiti P; Tsherniak, Aviad A; Vazquez, Francisca F; Wong, Bang B; Birger, Chet C; Ghandi, Mahmoud M; Thorner, Aaron R AR; Bittker, Joshua A JA; Meyerson, Matthew M; Getz, Gad G; Beroukhim, Rameen R; Golub, Todd R TR
Reliance upon ancestral mutations is maintained in colorectal cancers that heterogeneously evolve during targeted therapies.
Nature Communications
Russo, Mariangela M; Lamba, Simona S; Lorenzato, Annalisa A; Sogari, Alberto A; Corti, Giorgio G; Rospo, Giuseppe G; Mussolin, Benedetta B; Montone, Monica M; Lazzari, Luca L; Arena, Sabrina S; Oddo, Daniele D; Linnebacher, Michael M; Sartore-Bianchi, Andrea A; Pietrantonio, Filippo F; Siena, Salvatore S; Di Nicolantonio, Federica F; Bardelli, Alberto A
Development of a personalized therapeutic strategy for ERBB-gene-mutated cancers.
Therapeutic Advances In Medical Oncology
Milewska, Malgorzata M; Cremona, Mattia M; Morgan, Clare C; O'Shea, John J; Carr, Aoife A; Vellanki, Sri H SH; Hopkins, Ann M AM; Toomey, Sinead S; Madden, Stephen F SF; Hennessy, Bryan T BT; Eustace, Alex J AJ
CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells.
Gut
Manic, Gwenola G; Signore, Michele M; Sistigu, Antonella A; Russo, Giorgio G; Corradi, Francesca F; Siteni, Silvia S; Musella, Martina M; Vitale, Sara S; De Angelis, Maria Laura ML; Pallocca, Matteo M; Amoreo, Carla Azzurra CA; Sperati, Francesca F; Di Franco, Simone S; Barresi, Sabina S; Policicchio, Eleonora E; De Luca, Gabriele G; De Nicola, Francesca F; Mottolese, Marcella M; Zeuner, Ann A; Fanciulli, Maurizio M; Stassi, Giorgio G; Maugeri-Saccà, Marcello M; Baiocchi, Marta M; Tartaglia, Marco M; Vitale, Ilio I; De Maria, Ruggero R
Publication Date: 2018-05
Variant appearance in text: APC: 2557G>T; Glu853Ter
A Landscape of Pharmacogenomic Interactions in Cancer.
Cell
Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ
Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancer.
Oncotarget
Heerma van Voss, Marise R MR; Vesuna, Farhad F; Trumpi, Kari K; Brilliant, Justin J; Berlinicke, Cynthia C; de Leng, Wendy W; Kranenburg, Onno O; Offerhaus, G Johan GJ; Bürger, Horst H; van der Wall, Elsken E; van Diest, Paul J PJ; Raman, Venu V
Seshagiri, Somasekar S; Stawiski, Eric W EW; Durinck, Steffen S; Modrusan, Zora Z; Storm, Elaine E EE; Conboy, Caitlin B CB; Chaudhuri, Subhra S; Guan, Yinghui Y; Janakiraman, Vasantharajan V; Jaiswal, Bijay S BS; Guillory, Joseph J; Ha, Connie C; Dijkgraaf, Gerrit J P GJ; Stinson, Jeremy J; Gnad, Florian F; Huntley, Melanie A MA; Degenhardt, Jeremiah D JD; Haverty, Peter M PM; Bourgon, Richard R; Wang, Weiru W; Koeppen, Hartmut H; Gentleman, Robert R; Starr, Timothy K TK; Zhang, Zemin Z; Largaespada, David A DA; Wu, Thomas D TD; de Sauvage, Frederic J FJ
Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.
Molecular Cancer Therapeutics
Ikediobi, Ogechi N ON; Davies, Helen H; Bignell, Graham G; Edkins, Sarah S; Stevens, Claire C; O'Meara, Sarah S; Santarius, Thomas T; Avis, Tim T; Barthorpe, Syd S; Brackenbury, Lisa L; Buck, Gemma G; Butler, Adam A; Clements, Jody J; Cole, Jennifer J; Dicks, Ed E; Forbes, Simon S; Gray, Kristian K; Halliday, Kelly K; Harrison, Rachel R; Hills, Katy K; Hinton, Jonathan J; Hunter, Chris C; Jenkinson, Andy A; Jones, David D; Kosmidou, Vivienne V; Lugg, Richard R; Menzies, Andrew A; Mironenko, Tatiana T; Parker, Adrian A; Perry, Janet J; Raine, Keiran K; Richardson, David D; Shepherd, Rebecca R; Small, Alex A; Smith, Raffaella R; Solomon, Helen H; Stephens, Philip P; Teague, Jon J; Tofts, Calli C; Varian, Jennifer J; Webb, Tony T; West, Sofie S; Widaa, Sara S; Yates, Andy A; Reinhold, William W; Weinstein, John N JN; Stratton, Michael R MR; Futreal, P Andrew PA; Wooster, Richard R