APC c.4464_4467del ;(p.L1488Ffs*18)

Variant ID: 5-112175755-TATTA-T

NM_000038.5(APC):c.4464_4467del;(p.L1488Ffs*18)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Mutational Heterogeneity in APC and KRAS Arises at the Crypt Level and Leads to Polyclonality in Early Colorectal Tumorigenesis.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Gausachs, Mireia M; Borras, Ester E; Chang, Kyle K; Gonzalez, Sara S; Azuara, Daniel D; Delgado Amador, Axel A; Lopez-Doriga, Adriana A; San Lucas, F Anthony FA; Sanjuan, Xavier X; Paules, Maria J MJ; Taggart, Melissa W MW; Davies, Gareth E GE; Ehli, Erik A EA; Fowler, Jerry J; Moreno, Victor V; Pineda, Marta M; You, Y Nancy YN; Lynch, Patrick M PM; Lazaro, Conxi C; Navin, Nicholas E NE; Scheet, Paul A PA; Hawk, Ernest T ET; Capella, Gabriel G; Vilar, Eduardo E
Publication Date: 2017-10-01

Variant appearance in text: APC: 4464_4467del
PubMed Link: 28645942
Variant Present in the following documents:
  • Main text
View BVdb publication page



Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.

Molecular Cancer
Kovaleva, Valentina V; Geissler, Anna-Lena AL; Lutz, Lisa L; Fritsch, Ralph R; Makowiec, Frank F; Wiesemann, Sebastian S; Hopt, Ulrich T UT; Passlick, Bernward B; Werner, Martin M; Lassmann, Silke S
Publication Date: 2016-10-18

Variant appearance in text: N/A
PubMed Link: 27756406
Variant Present in the following documents:
View BVdb publication page