Identification of relevant genetic alterations in cancer using topological data analysis.
Nature Communications
Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG
Human colon organoids reveal distinct physiologic and oncogenic Wnt responses.
The Journal Of Experimental Medicine
Michels, Birgitta E BE; Mosa, Mohammed H MH; Grebbin, Britta M BM; Yepes, Diego D; Darvishi, Tahmineh T; Hausmann, Johannes J; Urlaub, Henning H; Zeuzem, Stefan S; Kvasnicka, Hans M HM; Oellerich, Thomas T; Farin, Henner F HF
Mutational Heterogeneity in APC and KRAS Arises at the Crypt Level and Leads to Polyclonality in Early Colorectal Tumorigenesis.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Gausachs, Mireia M; Borras, Ester E; Chang, Kyle K; Gonzalez, Sara S; Azuara, Daniel D; Delgado Amador, Axel A; Lopez-Doriga, Adriana A; San Lucas, F Anthony FA; Sanjuan, Xavier X; Paules, Maria J MJ; Taggart, Melissa W MW; Davies, Gareth E GE; Ehli, Erik A EA; Fowler, Jerry J; Moreno, Victor V; Pineda, Marta M; You, Y Nancy YN; Lynch, Patrick M PM; Lazaro, Conxi C; Navin, Nicholas E NE; Scheet, Paul A PA; Hawk, Ernest T ET; Capella, Gabriel G; Vilar, Eduardo E