APC c.4466T>G ;(p.L1489*)

Variant ID: 5-112175757-T-G

NM_000038.5(APC):c.4466T>G;(p.L1489*)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Molecular correlates and therapeutic targets in T cell-inflamed versus non-T cell-inflamed tumors across cancer types.

Genome Medicine
Bao, Riyue R; Stapor, Daniel D; Luke, Jason J JJ
Publication Date: 2020-10-27

Variant appearance in text: APC: L1489*
PubMed Link: 33106165
Variant Present in the following documents:
  • 13073_2020_787_MOESM1_ESM.xlsx, sheet 9
View BVdb publication page



Identification of relevant genetic alterations in cancer using topological data analysis.

Nature Communications
Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG
Publication Date: 2020-07-30

Variant appearance in text: APC: L1489*
PubMed Link: 32732999
Variant Present in the following documents:
  • 41467_2020_17659_MOESM3_ESM.xls, sheet 1
View BVdb publication page



Human colon organoids reveal distinct physiologic and oncogenic Wnt responses.

The Journal Of Experimental Medicine
Michels, Birgitta E BE; Mosa, Mohammed H MH; Grebbin, Britta M BM; Yepes, Diego D; Darvishi, Tahmineh T; Hausmann, Johannes J; Urlaub, Henning H; Zeuzem, Stefan S; Kvasnicka, Hans M HM; Oellerich, Thomas T; Farin, Henner F HF
Publication Date: 2019-03-04

Variant appearance in text: APC: L1489*
PubMed Link: 30792186
Variant Present in the following documents:
  • JEM_20180823_TableS5.xlsx, sheet 3
View BVdb publication page



SMAD4 and NF1 mutations as potential biomarkers for poor prognosis to cetuximab-based therapy in Chinese metastatic colorectal cancer patients.

Bmc Cancer
Mei, Zhu Z; Shao, Yang W YW; Lin, Peinan P; Cai, Xiaomin X; Wang, Biao B; Ding, Yan Y; Ma, Xiangyuan X; Wu, Xue X; Xia, Yewei Y; Zhu, Dongqin D; Shu, Yongqian Y; Fu, Zan Z; Gu, Yanhong Y
Publication Date: 2018-04-27

Variant appearance in text: APC: L1489X
PubMed Link: 29703253
Variant Present in the following documents:
  • 12885_2018_4298_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Mutational Heterogeneity in APC and KRAS Arises at the Crypt Level and Leads to Polyclonality in Early Colorectal Tumorigenesis.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Gausachs, Mireia M; Borras, Ester E; Chang, Kyle K; Gonzalez, Sara S; Azuara, Daniel D; Delgado Amador, Axel A; Lopez-Doriga, Adriana A; San Lucas, F Anthony FA; Sanjuan, Xavier X; Paules, Maria J MJ; Taggart, Melissa W MW; Davies, Gareth E GE; Ehli, Erik A EA; Fowler, Jerry J; Moreno, Victor V; Pineda, Marta M; You, Y Nancy YN; Lynch, Patrick M PM; Lazaro, Conxi C; Navin, Nicholas E NE; Scheet, Paul A PA; Hawk, Ernest T ET; Capella, Gabriel G; Vilar, Eduardo E
Publication Date: 2017-10-01

Variant appearance in text: APC: Leu1489*
PubMed Link: 28645942
Variant Present in the following documents:
  • Main text
View BVdb publication page