Synergistic antileukemic therapies in NOTCH1-induced T-ALL.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Sanchez-Martin, Marta M; Ambesi-Impiombato, Alberto A; Qin, Yue Y; Herranz, Daniel D; Bansal, Mukesh M; Girardi, Tiziana T; Paietta, Elisabeth E; Tallman, Martin S MS; Rowe, Jacob M JM; De Keersmaecker, Kim K; Califano, Andrea A; Ferrando, Adolfo A AA
DNMT3A(R882H) mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice.
Leukemia
Scourzic, L L; Couronné, L L; Pedersen, M T MT; Della Valle, V V; Diop, M M; Mylonas, E E; Calvo, J J; Mouly, E E; Lopez, C K CK; Martin, N N; Fontenay, M M; Bender, A A; Guibert, S S; Dubreuil, P P; Dessen, P P; Droin, N N; Pflumio, F F; Weber, M M; Gaulard, P P; Helin, K K; Mercher, T T; Bernard, O A OA
Mutational profiling of brain metastasis from breast cancer: matched pair analysis of targeted sequencing between brain metastasis and primary breast cancer.
Oncotarget
Lee, Ji Yun JY; Park, Kyunghee K; Lim, Sung Hee SH; Kim, Hae Su HS; Yoo, Kwai Han KH; Jung, Ki Sun KS; Song, Haa-Na HN; Hong, Mineui M; Do, In-Gu IG; Ahn, TaeJin T; Lee, Se Kyung SK; Bae, Soo Youn SY; Kim, Seok Won SW; Lee, Jeong Eon JE; Nam, Seok Jin SJ; Kim, Duk-Hwan DH; Jung, Hae Hyun HH; Kim, Ji-Yeon JY; Ahn, Jin Seok JS; Im, Young-Hyuck YH; Park, Yeon Hee YH
Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia.
Nature Medicine
Herranz, Daniel D; Ambesi-Impiombato, Alberto A; Sudderth, Jessica J; Sánchez-Martín, Marta M; Belver, Laura L; Tosello, Valeria V; Xu, Luyao L; Wendorff, Agnieszka A AA; Castillo, Mireia M; Haydu, J Erika JE; Márquez, Javier J; Matés, José M JM; Kung, Andrew L AL; Rayport, Stephen S; Cordon-Cardo, Carlos C; DeBerardinis, Ralph J RJ; Ferrando, Adolfo A AA
Patient-derived cell models as preclinical tools for genome-directed targeted therapy.
Oncotarget
Lee, Ji Yun JY; Kim, Sun Young SY; Park, Charny C; Kim, Nayoung K D NK; Jang, Jiryeon J; Park, Kyunghee K; Yi, Jun Ho JH; Hong, Mineui M; Ahn, Taejin T; Rath, Oliver O; Schueler, Julia J; Kim, Seung Tae ST; Do, In-Gu IG; Lee, Sujin S; Park, Se Hoon SH; Ji, Yong Ick YI; Kim, Dukwhan D; Park, Joon Oh JO; Park, Young Suk YS; Kang, Won Ki WK; Kim, Kyoung-Mee KM; Park, Woong-Yang WY; Lim, Ho Yeong HY; Lee, Jeeyun J
Molecular characterization of patients with pathologic complete response or early failure after neoadjuvant chemotherapy for locally advanced breast cancer using next generation sequencing and nCounter assay.
Oncotarget
Park, Kyunghee K; Choi, Moon Ki MK; Jung, Hae Hyun HH; Do, In-Gu IG; Lee, Kwang Hee KH; Ahn, TaeJin T; Kil, Won Ho WH; Kim, Seok Won SW; Lee, Jeong Eon JE; Nam, Seok Jin SJ; Kim, Duk-Hwan DH; Ahn, Jin Seok JS; Im, Young-Hyuck YH; Park, Yeon Hee YH
High-throughput sequencing and copy number variation detection using formalin fixed embedded tissue in metastatic gastric cancer.
Plos One
Kim, Seokhwi S; Lee, Jeeyun J; Hong, Min Eui ME; Do, In-Gu IG; Kang, So Young SY; Ha, Sang Yun SY; Kim, Seung Tae ST; Park, Se Hoon SH; Kang, Won Ki WK; Choi, Min-Gew MG; Lee, Jun Ho JH; Sohn, Tae Sung TS; Bae, Jae Moon JM; Kim, Sung S; Kim, Duk-Hwan DH; Kim, Kyoung-Mee KM
Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine.
Embo Molecular Medicine
Dias-Santagata, Dora D; Akhavanfard, Sara S; David, Serena S SS; Vernovsky, Kathy K; Kuhlmann, Georgiana G; Boisvert, Susan L SL; Stubbs, Hannah H; McDermott, Ultan U; Settleman, Jeffrey J; Kwak, Eunice L EL; Clark, Jeffrey W JW; Isakoff, Steven J SJ; Sequist, Lecia V LV; Engelman, Jeffrey A JA; Lynch, Thomas J TJ; Haber, Daniel A DA; Louis, David N DN; Ellisen, Leif W LW; Borger, Darrell R DR; Iafrate, A John AJ