Publications:

---

SMG6 regulates DNA damage and cell survival in Hippo pathway kinase LATS2-inactivated malignant mesothelioma.

Cell Death Discovery

Suzuki, Koya K; Tange, Masaki M; Yamagishi, Ryota R; Hanada, Hiroyuki H; Mukai, Satomi S; Sato, Tatsuhiro T; Tanaka, Takeshi T; Akashi, Tomohiro T; Kadomatsu, Kenji K; Maeda, Tohru T; Miida, Takashi T; Takeuchi, Ichiro I; Murakami, Hiroshi H; Sekido, Yoshitaka Y; Murakami-Tonami, Yuko Y

Publication Date: 2022-11-05

Variant appearance in text: TERT: D712A

PubMed Link: 36335095

Variant Present in the following documents:

• Main text
• 41420_2022_Article_1232.pdf

View BVdb publication page

---

A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution.

Elife

Paudel, Bishnu P BP; Moye, Aaron Lavel AL; Abou Assi, Hala H; El-Khoury, Roberto R; Cohen, Scott B SB; Holien, Jessica K JK; Birrento, Monica L ML; Samosorn, Siritron S; Intharapichai, Kamthorn K; Tomlinson, Christopher G CG; Teulade-Fichou, Marie-Paule MP; González, Carlos C; Beck, Jennifer L JL; Damha, Masad J MJ; van Oijen, Antoine M AM; Bryan, Tracy M TM

Publication Date: 2020-07-29

Variant appearance in text: TERT: D712A

PubMed Link: 32723475

Variant Present in the following documents:

• Main text
• elife-56428.pdf

View BVdb publication page

---

Telomerase Biogenesis and Activities from the Perspective of Its Direct Interacting Partners.

Cancers

Nguyen, Kathryn T T T KTTT; Wong, Judy M Y JMY

Publication Date: 2020-06-24

Variant appearance in text: TERT: D712A

PubMed Link: 32599885

Variant Present in the following documents:

• Main text
• cancers-12-01679.pdf

View BVdb publication page

---

Telomerase promotes formation of a telomere protective complex in cancer cells.

Science Advances

Perera, Omesha N ON; Sobinoff, Alexander P AP; Teber, Erdahl T ET; Harman, Ashley A; Maritz, Michelle F MF; Yang, Sile F SF; Pickett, Hilda A HA; Cesare, Anthony J AJ; Arthur, Jonathan W JW; MacKenzie, Karen L KL; Bryan, Tracy M TM

Publication Date: 2019-10

Variant appearance in text: TERT: D712A

PubMed Link: 31616780

Variant Present in the following documents:

• Main text
• aav4409.pdf
• aav4409_SM.pdf

View BVdb publication page

---

Enhanced cardiac repair by telomerase reverse transcriptase over-expression in human cardiac mesenchymal stromal cells.

Scientific Reports

Le, Thi Yen Loan TYL; Pickett, Hilda A HA; Yang, Andrian A; Ho, Joshua W K JWK; Thavapalachandran, Sujitha S; Igoor, Sindhu S; Yang, Sile F SF; Farraha, Melad M; Voges, Holly K HK; Hudson, James E JE; Dos Remedios, Cristobal G CG; Bryan, Tracy M TM; Kizana, Eddy E; Chong, James J H JJH

Publication Date: 2019-07-22

Variant appearance in text: TERT: D712A

PubMed Link: 31332256

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Structural, functional, and stability change predictions in human telomerase upon specific point mutations.

Scientific Reports

Kalathiya, U U; Padariya, M M; Baginski, M M

Publication Date: 2019-06-18

Variant appearance in text: TERT: D712A

PubMed Link: 31213647

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Transient introduction of human telomerase mRNA improves hallmarks of progeria cells.

Aging Cell

Li, Yanhui Y; Zhou, Gang G; Bruno, Ivone G IG; Zhang, Ning N; Sho, Sei S; Tedone, Enzo E; Lai, Tsung-Po TP; Cooke, John P JP; Shay, Jerry W JW

Publication Date: 2019-08

Variant appearance in text: TERT: D712A

PubMed Link: 31152494

Variant Present in the following documents:

• Main text
• ACEL-18-e12979.pdf

View BVdb publication page

---

Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression.

The Journal Of Clinical Investigation

Khattar, Ekta E; Kumar, Pavanish P; Liu, Chia Yi CY; Akıncılar, Semih Can SC; Raju, Anandhkumar A; Lakshmanan, Manikandan M; Maury, Julien Jean Pierre JJ; Qiang, Yu Y; Li, Shang S; Tan, Ern Yu EY; Hui, Kam M KM; Shi, Ming M; Loh, Yuin Han YH; Tergaonkar, Vinay V

Publication Date: 2016-10-03

Variant appearance in text: TERT: D712A

PubMed Link: 27643433

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Enhancement of the in vivo persistence and antitumor efficacy of CD19 chimeric antigen receptor T cells through the delivery of modified TERT mRNA.

Cell Discovery

Bai, Yun Y; Kan, Shifeng S; Zhou, Shixin S; Wang, Yuting Y; Xu, Jun J; Cooke, John P JP; Wen, Jinhua J; Deng, Hongkui H

Publication Date: 2015

Variant appearance in text: TERT: D712A

PubMed Link: 27462436

Variant Present in the following documents:

• Main text
• celldisc201540.pdf

View BVdb publication page

---

The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres.

Plos Genetics

Frank, Amanda K AK; Tran, Duy C DC; Qu, Roy W RW; Stohr, Bradley A BA; Segal, David J DJ; Xu, Lifeng L

Publication Date: 2015-07

Variant appearance in text: TERT: D712A

PubMed Link: 26230315

Variant Present in the following documents:

• Main text
• pgen.1005410.pdf

View BVdb publication page

---

Telomerase activity-independent function of TERT allows glioma cells to attain cancer stem cell characteristics by inducing EGFR expression.

Molecules And Cells

Beck, Samuel S; Jin, Xun X; Sohn, Young-Woo YW; Kim, Jun-Kyum JK; Kim, Sung-Hak SH; Yin, Jinlong J; Pian, Xumin X; Kim, Sung-Chan SC; Nam, Do-Hyun DH; Choi, Yun-Jaie YJ; Kim, Hyunggee H

Publication Date: 2011-01

Variant appearance in text: TERT: D712A

PubMed Link: 21193962

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Human telomerase catalytic subunit (hTERT) suppresses p53-mediated anti-apoptotic response via induction of basic fibroblast growth factor.

Experimental & Molecular Medicine

Jin, Xun X; Beck, Samuel S; Sohn, Young-Woo YW; Kim, Jun-Kyum JK; Kim, Sung-Hak SH; Yin, Jinlong J; Pian, Xumin X; Kim, Sung-Chan SC; Choi, Yun-Jaie YJ; Kim, Hyunggee H

Publication Date: 2010-08-31

Variant appearance in text: TERT: D712A

PubMed Link: 20628269

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genetic hypervariability in two distinct deuterostome telomerase reverse transcriptase genes and their early embryonic functions.

Molecular Biology Of The Cell

Wells, Trystan B TB; Zhang, Guanglei G; Harley, Zenon Z; Vaziri, Homayoun H

Publication Date: 2009-01

Variant appearance in text: TERT: D712A

PubMed Link: 18946080

Variant Present in the following documents:

• Main text

View BVdb publication page

---

TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program.

Plos Genetics

Choi, Jinkuk J; Southworth, Lucinda K LK; Sarin, Kavita Y KY; Venteicher, Andrew S AS; Ma, Wenxiu W; Chang, Woody W; Cheung, Peggie P; Jun, Sohee S; Artandi, Maja K MK; Shah, Naman N; Kim, Stuart K SK; Artandi, Steven E SE

Publication Date: 2008-01

Variant appearance in text: TERT: D712A

PubMed Link: 18208333

Variant Present in the following documents:

View BVdb publication page

---

p53-dependent integration of telomere and growth factor deprivation signals.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Beliveau, Alain A; Bassett, Ekaterina E; Lo, Alvin T AT; Garbe, James J; Rubio, Miguel A MA; Bissell, Mina J MJ; Campisi, Judith J; Yaswen, Paul P

Publication Date: 2007-03-13

Variant appearance in text: TERT: D712A

PubMed Link: 17360541

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Characterization of physical and functional anchor site interactions in human telomerase.

Molecular And Cellular Biology

Wyatt, Haley D M HD; Lobb, Deirdre A DA; Beattie, Tara L TL

Publication Date: 2007-04

Variant appearance in text: TERT: D712A

PubMed Link: 17296728

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Functional multimerization of the human telomerase reverse transcriptase.

Molecular And Cellular Biology

Beattie, T L TL; Zhou, W W; Robinson, M O MO; Harrington, L L

Publication Date: 2001-09

Variant appearance in text: TERT: D712A

PubMed Link: 11509658

Variant Present in the following documents:

• Main text

View BVdb publication page

---