TERT c.2120A>T ;(p.Y707F)

Variant ID: 5-1279416-T-A

NM_198253.2(TERT):c.2120A>T;(p.Y707F)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Many Functions of Telomerase Components: Certainties, Doubts, and Inconsistencies.

International Journal Of Molecular Sciences
Udroiu, Ion I; Marinaccio, Jessica J; Sgura, Antonella A
Publication Date: 2022-12-02

Variant appearance in text: TERT: Y707F
PubMed Link: 36499514
Variant Present in the following documents:
  • Main text
  • ijms-23-15189.pdf
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The emerging role of telomerase reverse transcriptase in mitochondrial DNA metabolism.

Journal Of Nucleic Acids
Gordon, Donna M DM; Santos, Janine Hertzog JH
Publication Date: 2010-09-21

Variant appearance in text: TERT: Y707F
PubMed Link: 20936168
Variant Present in the following documents:
  • Main text
  • JNA2010-390791.pdf
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Nuclear protein tyrosine phosphatase Shp-2 is one important negative regulator of nuclear export of telomerase reverse transcriptase.

The Journal Of Biological Chemistry
Jakob, Sascha S; Schroeder, Peter P; Lukosz, Margarete M; Büchner, Nicole N; Spyridopoulos, Ioakim I; Altschmied, Joachim J; Haendeler, Judith J
Publication Date: 2008-11-28

Variant appearance in text: TERT: Y707F
PubMed Link: 18829466
Variant Present in the following documents:
  • Main text
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Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.

Molecular And Cellular Biology
Haendeler, Judith J; Hoffmann, Jörg J; Brandes, Ralf P RP; Zeiher, Andreas M AM; Dimmeler, Stefanie S
Publication Date: 2003-07

Variant appearance in text: TERT: Y707F
PubMed Link: 12808100
Variant Present in the following documents:
  • Main text
View BVdb publication page