TERT c.314A>C ;(p.D105A)

Variant ID: 5-1294687-T-G

NM_198253.2(TERT):c.314A>C;(p.D105A)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Highly similar structural frames link the template tunnel and NTP entry tunnel to the exterior surface in RNA-dependent RNA polymerases.

Nucleic Acids Research
Lang, Dorothy M DM; Zemla, A T AT; Zhou, C L Ecale CL
Publication Date: 2013-02-01

Variant appearance in text: TERT: D105A
PubMed Link: 23275546
Variant Present in the following documents:
  • Main text
  • gks1251.pdf
View BVdb publication page



The N-terminus of hTERT contains a DNA-binding domain and is required for telomerase activity and cellular immortalization.

Nucleic Acids Research
Sealey, David C F DC; Zheng, Le L; Taboski, Michael A S MA; Cruickshank, Jennifer J; Ikura, Mitsuhiko M; Harrington, Lea A LA
Publication Date: 2010-04

Variant appearance in text: TERT: D105A
PubMed Link: 20034955
Variant Present in the following documents:
  • Main text
  • gkp1160.pdf
View BVdb publication page