Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma.
Frontiers In Oncology
Wong, Rachel L Y RLY; Wong, Megan R E MRE; Kuick, Chik Hong CH; Saffari, Seyed Ehsan SE; Wong, Meng Kang MK; Tan, Sheng Hui SH; Merchant, Khurshid K; Chang, Kenneth T E KTE; Thangavelu, Matan M; Periyasamy, Giridharan G; Chen, Zhi Xiong ZX; Iyer, Prasad P; Tan, Enrica E K EEK; Soh, Shui Yen SY; Iyer, N Gopalakrishna NG; Fan, Qiao Q; Loh, Amos H P AHP
A genetic variant in telomerase reverse transcriptase (TERT) modifies cancer risk in Lynch syndrome patients harbouring pathogenic MSH2 variants.
Scientific Reports
Wiik, Mariann Unhjem MU; Evans, Tiffany-Jane TJ; Belhadj, Sami S; Bolton, Katherine A KA; Dymerska, Dagmara D; Jagmohan-Changur, Shantie S; Capellá, Gabriel G; Kurzawski, Grzegorz G; Wijnen, Juul T JT; Valle, Laura L; Vasen, Hans F A HFA; Lubinski, Jan J; Scott, Rodney J RJ; Talseth-Palmer, Bente A BA
Germline variants are associated with increased primary melanoma tumor thickness at diagnosis.
Human Molecular Genetics
Mangantig, Ernest E; MacGregor, Stuart S; Iles, Mark M MM; Scolyer, Richard A RA; Cust, Anne E AE; Hayward, Nicholas K NK; Montgomery, Grant W GW; Duffy, David L DL; Thompson, John F JF; Henders, Anjali A; Bowdler, Lisa L; Rowe, Casey C; Cadby, Gemma G; Mann, Graham J GJ; Whiteman, David C DC; Long, Georgina V GV; Ward, Sarah V SV; Khosrotehrani, Kiarash K; Barrett, Jennifer H JH; Law, Matthew H MH
The predictive capability of immunohistochemistry and DNA sequencing for determining TP53 functional mutation status: a comparative study of 41 glioblastoma patients.
Oncotarget
Roshandel, Aarash K AK; Busch, Christopher M CM; Mullekom, Jennifer Van JV; Cuoco, Joshua A JA; Rogers, Cara M CM; Apfel, Lisa S LS; Marvin, Eric A EA; Sontheimer, Harald W HW; Umans, Robyn A RA
Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies.
Scientific Reports
Wang, Junjun J; Liu, Qingyun Q; Yuan, Shuai S; Xie, Weijia W; Liu, Yuan Y; Xiang, Ying Y; Wu, Na N; Wu, Long L; Ma, Xiangyu X; Cai, Tongjian T; Zhang, Yao Y; Sun, Zhifu Z; Li, Yafei Y
The Anatomy to Genomics (ATG) Start Genetics medical school initiative: incorporating exome sequencing data from cadavers used for Anatomy instruction into the first year curriculum.
Bmc Medical Genomics
Gerhard, Glenn S GS; Jin, Qunyan Q; Paynton, Barbara V BV; Popoff, Steven N SN
A Comparative Analysis of Genetic and Epigenetic Events of Breast and Ovarian Cancer Related to Tumorigenesis.
International Journal Of Molecular Sciences
Longacre, Mckenna M; Snyder, Nicole A NA; Housman, Genevieve G; Leary, Meghan M; Lapinska, Karolina K; Heerboth, Sarah S; Willbanks, Amber A; Sarkar, Sibaji S
Publication Date: 2016-05-18
Variant appearance in text: TERT: 215G>C; Arg72Pro