Publications:

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The Many Ways to Deal with STING.

International Journal Of Molecular Sciences

Coderch, Claire C; Arranz-Herrero, Javier J; Nistal-Villan, Estanislao E; de Pascual-Teresa, Beatriz B; Rius-Rocabert, Sergio S

Publication Date: 2023-05-20

Variant appearance in text: STING: N154S

PubMed Link: 37240378

Variant Present in the following documents:

• Main text
• ijms-24-09032.pdf

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Regulation and function of the cGAS-MITA/STING axis in health and disease.

Cell Insight

Zhang, Zhi-Dong ZD; Zhong, Bo B

Publication Date: 2022-02

Variant appearance in text: MITA: N154S

PubMed Link: 37192983

Variant Present in the following documents:

• Main text
• main.pdf

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Termination of STING responses is mediated via ESCRT-dependent degradation.

The Embo Journal

Balka, Katherine R KR; Venkatraman, Rajan R; Saunders, Tahnee L TL; Shoppee, Angus A; Pang, Ee Shan ES; Magill, Zoe Z; Homman-Ludiye, Jihane J; Huang, Cheng C; Lane, Rachael M RM; York, Harrison M HM; Tan, Peck P; Schittenhelm, Ralf B RB; Arumugam, Senthil S; Kile, Benjamin T BT; O'Keeffe, Meredith M; De Nardo, Dominic D

Publication Date: 2023-05-04

Variant appearance in text: STING: N154S

PubMed Link: 37139896

Variant Present in the following documents:

• Main text
• EMBJ-42-e112712-s016.pdf
• EMBJ-42-e112712-s009.pdf
• EMBJ-42-e112712.pdf

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Potential Therapeutic Value of the STING Inhibitors.

Molecules (Basel, Switzerland)

Zhang, Shangran S; Zheng, Runan R; Pan, Yanhong Y; Sun, Hongbin H

Publication Date: 2023-03-31

Variant appearance in text: STING: N154S

PubMed Link: 37049889

Variant Present in the following documents:

• Main text
• molecules-28-03127.pdf

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Current understanding of the cGAS-STING signaling pathway: Structure, regulatory mechanisms, and related diseases.

Zoological Research

Pan, Jing J; Fei, Chen-Jie CJ; Hu, Yang Y; Wu, Xiang-Yu XY; Nie, Li L; Chen, Jiong J

Publication Date: 2023-01-18

Variant appearance in text: STING: Asn154Ser

PubMed Link: 36579404

Variant Present in the following documents:

• Main text
• zr-44-1-183.pdf

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Use of Tofacitinib for infant-onset STING-associated vasculopathy: A case report from China.

Medicine

Shen, Danping D; Fan, Xiaorui X; Zhou, Qing Q; Xu, Xuefeng X; Lu, Meiping M

Publication Date: 2022-12-02

Variant appearance in text: STING: N154S

PubMed Link: 36482559

Variant Present in the following documents:

• medi-101-e31832.pdf

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Regulation of cGAS-STING Pathway - Implications for Systemic Lupus Erythematosus.

Rheumatology And Immunology Research

Hagiwara, Audrey M AM; Moore, Richard E RE; Wallace, Daniel J DJ; Ishimori, Mariko M; Jefferies, Caroline A CA

Publication Date: 2021-09

Variant appearance in text: STING: N154S

PubMed Link: 36465073

Variant Present in the following documents:

• Main text
• rir-02-173.pdf

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The activity of disease-causative STING variants can be suppressed by wild-type STING through heterocomplex formation.

Frontiers In Cell And Developmental Biology

Shindo, Ruri R; Kuchitsu, Yoshihiko Y; Mukai, Kojiro K; Taguchi, Tomohiko T

Publication Date: 2022

Variant appearance in text: STING: N154S

PubMed Link: 36438571

Variant Present in the following documents:

• Main text
• fcell-10-1037999.pdf

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Epigenetically suppressed tumor cell intrinsic STING promotes tumor immune escape.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie

Zheng, Hui H; Wu, Lizhen L; Xiao, Qian Q; Meng, Xin X; Hafiz, Alex A; Yan, Qin Q; Lu, Renquan R; Cao, Jian J

Publication Date: 2022-11-24

Variant appearance in text: STING: N154S

PubMed Link: 36436495

Variant Present in the following documents:

• Main text
• nihms-1856183.pdf

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Human induced pluripotent stem cells generated from STING-associated vasculopathy with onset in infancy (SAVI) patients with a heterozygous mutation in the STING gene.

Stem Cell Research

Mehta, Atul A; Yu, Quan Q; Liu, Yangtengyu Y; Yang, Dan D; Zou, Jizhong J; Beers, Jeanette J; de Jesus Rasheed, Adriana A AA; Rastegar, Andrew T AT; Goldbach-Mansky, Raphaela R; Boehm, Manfred M; Chen, Guibin G

Publication Date: 2022-12

Variant appearance in text: STING: N154S

PubMed Link: 36399927

Variant Present in the following documents:

• nihms-1852517.pdf

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Clathrin-associated AP-1 controls termination of STING signalling.

Nature

Liu, Ying Y; Xu, Pengbiao P; Rivara, Sophie S; Liu, Chong C; Ricci, Jonathan J; Ren, Xuefeng X; Hurley, James H JH; Ablasser, Andrea A

Publication Date: 2022-10

Variant appearance in text: STING: N154S

PubMed Link: 36261523

Variant Present in the following documents:

• Main text
• 41586_2022_Article_5354.pdf

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Primary immunodeficiencies in Bulgaria - achievements and challenges of the PID National Expert Center.

Frontiers In Immunology

Naumova, Elissaveta E; Lesichkova, Spaska S; Milenova, Veneta V; Yankova, Petya P; Murdjeva, Marianna M; Mihailova, Snezhina S

Publication Date: 2022

Variant appearance in text: STING1: 461A>G; Asn154Ser

PubMed Link: 36211402

Variant Present in the following documents:

• DataSheet_1.pdf

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Inhibitory targeting cGAS-STING-TBK1 axis: Emerging strategies for autoimmune diseases therapy.

Frontiers In Immunology

Zhang, Min M; Zou, Yan Y; Zhou, Xujun X; Zhou, Jinming J

Publication Date: 2022

Variant appearance in text: STING: N154S

PubMed Link: 36172373

Variant Present in the following documents:

• Main text
• fimmu-13-954129.pdf

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Activation of STING Based on Its Structural Features.

Frontiers In Immunology

Hussain, Behzad B; Xie, Yufeng Y; Jabeen, Uzma U; Lu, Defen D; Yang, Bo B; Wu, Changxin C; Shang, Guijun G

Publication Date: 2022

Variant appearance in text: STING: N154S

PubMed Link: 35928815

Variant Present in the following documents:

• Main text
• fimmu-13-808607.pdf

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The cGAS-STING Pathway Affects Vertebral Bone but Does Not Promote Intervertebral Disc Cell Senescence or Degeneration.

Frontiers In Immunology

Ottone, Olivia K OK; Kim, Cheeho C; Collins, John A JA; Risbud, Makarand V MV

Publication Date: 2022

Variant appearance in text: STING: N154S

PubMed Link: 35769461

Variant Present in the following documents:

• Main text
• fimmu-13-882407.pdf

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STING controls energy stress-induced autophagy and energy metabolism via STX17.

The Journal Of Cell Biology

Rong, Yueguang Y; Zhang, Shen S; Nandi, Nilay N; Wu, Zhe Z; Li, Linsen L; Liu, Yang Y; Wei, Yuehan Y; Zhao, Yuan Y; Yuan, Weigang W; Zhou, Chuchu C; Xiao, Guanghua G; Levine, Beth B; Yan, Nan N; Mou, Shan S; Deng, Liufu L; Tang, Zaiming Z; Liu, Xiaoxia X; Kramer, Helmut H; Zhong, Qing Q

Publication Date: 2022-07-04

Variant appearance in text: STING: N154S

PubMed Link: 35510944

Variant Present in the following documents:

• Main text
• JCB_202202060.pdf

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Janus Kinase Inhibitors in the Treatment of Type I Interferonopathies: A Case Series From a Single Center in China.

Frontiers In Immunology

Li, Wendao W; Wang, Wei W; Wang, Wei W; Zhong, Linqing L; Gou, Lijuan L; Wang, Changyan C; Ma, Jingran J; Quan, Meiying M; Jian, Shan S; Tang, Xiaoyan X; Zhang, Yu Y; Wang, Lin L; Ma, Mingsheng M; Song, Hongmei H

Publication Date: 2022

Variant appearance in text: TMEM173: N154S

PubMed Link: 35418997

Variant Present in the following documents:

• fimmu-13-825367.pdf

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STING1 in Different Organelles: Location Dictates Function.

Frontiers In Immunology

Zhang, Ruoxi R; Kang, Rui R; Tang, Daolin D

Publication Date: 2022

Variant appearance in text: STING1: N154S

PubMed Link: 35371032

Variant Present in the following documents:

• Main text
• fimmu-13-842489.pdf

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Lung Inflammation in STING-Associated Vasculopathy with Onset in Infancy (SAVI).

Cells

David, Clémence C; Frémond, Marie-Louise ML

Publication Date: 2022-01-18

Variant appearance in text: STING: N154S

PubMed Link: 35159128

Variant Present in the following documents:

• Main text

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Lung Inflammation in STING-Associated Vasculopathy with Onset in Infancy (SAVI).

Cells

David, Clémence C; Frémond, Marie-Louise ML

Publication Date: 2022-01-18

Variant appearance in text: STING: N154S

PubMed Link: 35159128

Variant Present in the following documents:

• Main text

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The cGAS-STING signaling in cardiovascular and metabolic diseases: Future novel target option for pharmacotherapy.

Acta Pharmaceutica Sinica. B

Oduro, Patrick Kwabena PK; Zheng, Xianxian X; Wei, Jinna J; Yang, Yanze Y; Wang, Yuefei Y; Zhang, Han H; Liu, Erwei E; Gao, Xiumei X; Du, Mei M; Wang, Qilong Q

Publication Date: 2022-01

Variant appearance in text: STING: N154S

PubMed Link: 35127372

Variant Present in the following documents:

• Main text
• main.pdf

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The transmembrane endoplasmic reticulum-associated E3 ubiquitin ligase TRIM13 restrains the pathogenic-DNA-triggered inflammatory response.

Science Advances

Li, Xuelian X; Yu, Zhou Z; Fang, Qian Q; Yang, Mingjin M; Huang, Jiaying J; Li, Zheng Z; Wang, Jianli J; Chen, Taoyong T

Publication Date: 2022-01-28

Variant appearance in text: STING: N154S

PubMed Link: 35080984

Variant Present in the following documents:

• Main text
• sciadv.abh0496.pdf

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The transmembrane endoplasmic reticulum-associated E3 ubiquitin ligase TRIM13 restrains the pathogenic-DNA-triggered inflammatory response.

Science Advances

Li, Xuelian X; Yu, Zhou Z; Fang, Qian Q; Yang, Mingjin M; Huang, Jiaying J; Li, Zheng Z; Wang, Jianli J; Chen, Taoyong T

Publication Date: 2022-01-28

Variant appearance in text: STING: N154S

PubMed Link: 35080984

Variant Present in the following documents:

• Main text
• sciadv.abh0496.pdf

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The cGAS-STING Pathway: A Promising Immunotherapy Target.

Frontiers In Immunology

Ou, Liang L; Zhang, Ao A; Cheng, Yuxing Y; Chen, Ying Y

Publication Date: 2021

Variant appearance in text: STING: N154S

PubMed Link: 34956229

Variant Present in the following documents:

• Main text

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STING Signaling and Sterile Inflammation.

Frontiers In Immunology

Couillin, Isabelle I; Riteau, Nicolas N

Publication Date: 2021

Variant appearance in text: TMEM173: N154S

PubMed Link: 34659260

Variant Present in the following documents:

• Main text
• fimmu-12-753789.pdf

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STING inhibitors target the cyclic dinucleotide binding pocket.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Hong, Ze Z; Mei, Jiahao J; Li, Chenhui C; Bai, Guohui G; Maimaiti, Munire M; Hu, Haiyang H; Yu, Wenying W; Sun, Li L; Zhang, Lele L; Cheng, Dan D; Liao, Yixian Y; Li, Senlin S; You, Yanping Y; Sun, Hongbin H; Huang, Jing J; Liu, Xing X; Lieberman, Judy J; Wang, Chen C

Publication Date: 2021-06-15

Variant appearance in text: STING: N154S

PubMed Link: 34099558

Variant Present in the following documents:

• Main text
• pnas.202105465.pdf

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STING Operation at the ER/Golgi Interface.

Frontiers In Immunology

Taguchi, Tomohiko T; Mukai, Kojiro K; Takaya, Eiko E; Shindo, Ruri R

Publication Date: 2021

Variant appearance in text: STING: N154S

PubMed Link: 34012437

Variant Present in the following documents:

• Main text
• fimmu-12-646304.pdf

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Efficacy and Safety of Janus Kinase Inhibitors in Type I Interferon-Mediated Monogenic Autoinflammatory Disorders: A Scoping Review.

Dermatology And Therapy

Gómez-Arias, Pedro Jesús PJ; Gómez-García, Francisco F; Hernández-Parada, Jorge J; Montilla-López, Ana María AM; Ruano, Juan J; Parra-Peralbo, Esmeralda E

Publication Date: 2021-06

Variant appearance in text: TMEM173: N154S

PubMed Link: 33856640

Variant Present in the following documents:

• Main text

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Case Report: Novel SAVI-Causing Variants in STING1 Expand the Clinical Disease Spectrum and Suggest a Refined Model of STING Activation.

Frontiers In Immunology

Lin, Bin B; Torreggiani, Sofia S; Kahle, Dana D; Rumsey, Dax G DG; Wright, Benjamin L BL; Montes-Cano, Marco A MA; Silveira, Laura Fernandez LF; Alehashemi, Sara S; Mitchell, Jacob J; Aue, Alexander G AG; Ji, Zheng Z; Jin, Tengchuan T; de Jesus, Adriana A AA; Goldbach-Mansky, Raphaela R

Publication Date: 2021

Variant appearance in text: STING: N154S

PubMed Link: 33833757

Variant Present in the following documents:

• Main text

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The cGAS-STING pathway as a therapeutic target in inflammatory diseases.

Nature Reviews. Immunology

Decout, Alexiane A; Katz, Jason D JD; Venkatraman, Shankar S; Ablasser, Andrea A

Publication Date: 2021-09

Variant appearance in text: STING: N154S

PubMed Link: 33833439

Variant Present in the following documents:

• Main text
• 41577_2021_Article_524.pdf

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The cGAS-STING pathway as a therapeutic target in inflammatory diseases.

Nature Reviews. Immunology

Decout, Alexiane A; Katz, Jason D JD; Venkatraman, Shankar S; Ablasser, Andrea A

Publication Date: 2021-09

Variant appearance in text: STING: N154S

PubMed Link: 33833439

Variant Present in the following documents:

• Main text
• 41577_2021_Article_524.pdf

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The Trinity of cGAS, TLR9, and ALRs Guardians of the Cellular Galaxy Against Host-Derived Self-DNA.

Frontiers In Immunology

Kumar, Vijay V

Publication Date: 2020

Variant appearance in text: STING: N154S

PubMed Link: 33643304

Variant Present in the following documents:

• Main text

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Signaling Through Nucleic Acid Sensors and Their Roles in Inflammatory Diseases.

Frontiers In Immunology

Okude, Haruna H; Ori, Daisuke D; Kawai, Taro T

Publication Date: 2020

Variant appearance in text: STING: N154S

PubMed Link: 33633744

Variant Present in the following documents:

• Main text
• fimmu-11-625833.pdf

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STING-associated vasculopathy with onset in infancy: a familial case series report and literature review.

Annals Of Translational Medicine

Wang, Yan Y; Wang, Fan F; Zhang, Xiaolei X

Publication Date: 2021-01

Variant appearance in text: STING: N154S

PubMed Link: 33569478

Variant Present in the following documents:

• Main text
• atm-09-02-176.pdf

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A Novel Biallelic STING1 Gene Variant Causing SAVI in Two Siblings.

Frontiers In Immunology

Alghamdi, Malak Ali MA; Mulla, Jaazeel J; Saheb Sharif-Askari, Narjes N; Guzmán-Vega, Francisco J FJ; Arold, Stefan T ST; Abd-Alwahed, Mervat M; Alharbi, Nasser N; Kashour, Tarek T; Halwani, Rabih R

Publication Date: 2020

Variant appearance in text: TMEM173: 461A>G

PubMed Link: 33488593

Variant Present in the following documents:

View BVdb publication page

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Stimulator of Interferon Genes-Associated Vasculopathy With Onset in Infancy: A Systematic Review of Case Reports.

Frontiers In Pediatrics

Dai, YunFan Y; Liu, XiuYun X; Zhao, ZhiPeng Z; He, JianXin J; Yin, QingQin Q

Publication Date: 2020

Variant appearance in text: STING: N154S

PubMed Link: 33425809

Variant Present in the following documents:

• Main text

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Lymphocyte Changes in Severe COVID-19: Delayed Over-Activation of STING?

Frontiers In Immunology

Berthelot, Jean-Marie JM; Lioté, Frédéric F; Maugars, Yves Y; Sibilia, Jean J

Publication Date: 2020

Variant appearance in text: STING: N154S

PubMed Link: 33335532

Variant Present in the following documents:

• Main text
• fimmu-11-607069.pdf

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Stimulator of Interferon Genes-associated Vasculopathy with an Onset in Infancy Diagnosed after the Development of Atypical Pulmonary Lesions During Treatment as Juvenile Idiopathic Arthritis.

Internal Medicine (Tokyo, Japan)

Nishida, Tomoya T; Nakano, Kazuhisa K; Inoue, Yoshino Y; Narumi-Kishimoto, Yoko Y; Kaname, Tadashi T; Akashi, Koichi K; Tanaka, Yoshiya Y

Publication Date: 2021-04-01

Variant appearance in text: STING: N154S

PubMed Link: 33162473

Variant Present in the following documents:

• Main text
• 1349-7235-60-1109.pdf

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Familial Interstitial Lung Disease Caused by Mutation of the STING1 Gene.

Frontiers In Pediatrics

Li, Jinying J; An, Shuhua S; Du, Zhongdong Z

Publication Date: 2020

Variant appearance in text: STING1: N154S

PubMed Link: 33014937

Variant Present in the following documents:

• Main text

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cGAS-STING pathway in cancer biotherapy.

Molecular Cancer

Wang, Yang Y; Luo, Jingwen J; Alu, Aqu A; Han, Xuejiao X; Wei, Yuquan Y; Wei, Xiawei X

Publication Date: 2020-09-04

Variant appearance in text: STING: N154S

PubMed Link: 32887628

Variant Present in the following documents:

• Main text
• 12943_2020_Article_1247.pdf

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The cGAS-STING pathway: The role of self-DNA sensing in inflammatory lung disease.

Faseb Journal : Official Publication Of The Federation Of American Societies For Experimental Biology

Ma, Ruihua R; Ortiz Serrano, Tatiana P TP; Davis, Jennifer J; Prigge, Andrew D AD; Ridge, Karen M KM

Publication Date: 2020-10

Variant appearance in text: TMEM173: N154S

PubMed Link: 32860267

Variant Present in the following documents:

• Main text
• nihms-1666765.pdf

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