ADRB2 c.491C>T ;(p.T164I)

Variant ID: 5-148206885-C-T

NM_000024.5(ADRB2):c.491C>T;(p.T164I)

This variant was identified in 116 publications

View GRCh38 version.




Publications:


Immunogenetics and pharmacogenetics of allergic asthma in Africa.

Frontiers In Allergy
Mabelane, Tshegofatso T; Masekela, Refiloe R; Dandara, Collet C; Hadebe, Sabelo S
Publication Date: 2023

Variant appearance in text: ADRB2: Thr164Ile; rs1800888
PubMed Link: 37228580
Variant Present in the following documents:
  • Main text
  • falgy-04-1165311.pdf
View BVdb publication page



A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Jang, H Josh HJ; Hostetter, Galen G; MacFarlane, Alexander W AW; Madaj, Zachary Z; Ross, Eric A EA; Hinoue, Toshinori T; Kulchycki, Justin R JR; Burgos, Ryan S RS; Tafseer, Mahvish M; Alpaugh, R Katherine RK; Schwebel, Candice L CL; Kokate, Rutika R; Geynisman, Daniel M DM; Zibelman, Matthew R MR; Ghatalia, Pooja P; Nichols, Peter W PW; Chung, Woonbok W; Madzo, Jozef J; Hahn, Noah M NM; Quinn, David I DI; Issa, Jean-Pierre J JJ; Topper, Michael J MJ; Baylin, Stephen B SB; Shen, Hui H; Campbell, Kerry S KS; Jones, Peter A PA; Plimack, Elizabeth R ER
Publication Date: 2023-03-16

Variant appearance in text: ADRB2: T164I
PubMed Link: 36928921
Variant Present in the following documents:
  • ccr-22-3642_supplementary_tables_1_suppts1.xlsx, sheet 3
View BVdb publication page



Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk.

Nature Genetics
Shrine, Nick N; Izquierdo, Abril G AG; Chen, Jing J; Packer, Richard R; Hall, Robert J RJ; Guyatt, Anna L AL; Batini, Chiara C; Thompson, Rebecca J RJ; Pavuluri, Chandan C; Malik, Vidhi V; Hobbs, Brian D BD; Moll, Matthew M; Kim, Wonji W; Tal-Singer, Ruth R; Bakke, Per P; Fawcett, Katherine A KA; John, Catherine C; Coley, Kayesha K; Piga, Noemi Nicole NN; Pozarickij, Alfred A; Lin, Kuang K; Millwood, Iona Y IY; Chen, Zhengming Z; Li, Liming L; , ; Wijnant, Sara R A SRA; Lahousse, Lies L; Brusselle, Guy G; Uitterlinden, Andre G AG; Manichaikul, Ani A; Oelsner, Elizabeth C EC; Rich, Stephen S SS; Barr, R Graham RG; Kerr, Shona M SM; Vitart, Veronique V; Brown, Michael R MR; Wielscher, Matthias M; Imboden, Medea M; Jeong, Ayoung A; Bartz, Traci M TM; Gharib, Sina A SA; Flexeder, Claudia C; Karrasch, Stefan S; Gieger, Christian C; Peters, Annette A; Stubbe, Beate B; Hu, Xiaowei X; Ortega, Victor E VE; Meyers, Deborah A DA; Bleecker, Eugene R ER; Gabriel, Stacey B SB; Gupta, Namrata N; Smith, Albert Vernon AV; Luan, Jian'an J; Zhao, Jing-Hua JH; Hansen, Ailin F AF; Langhammer, Arnulf A; Willer, Cristen C; Bhatta, Laxmi L; Porteous, David D; Smith, Blair H BH; Campbell, Archie A; Sofer, Tamar T; Lee, Jiwon J; Daviglus, Martha L ML; Yu, Bing B; Lim, Elise E; Xu, Hanfei H; O'Connor, George T GT; Thareja, Gaurav G; Albagha, Omar M E OME; , ; Suhre, Karsten K; Granell, Raquel R; Faquih, Tariq O TO; Hiemstra, Pieter S PS; Slats, Annelies M AM; Mullin, Benjamin H BH; Hui, Jennie J; James, Alan A; Beilby, John J; Patasova, Karina K; Hysi, Pirro P; Koskela, Jukka T JT; Wyss, Annah B AB; Jin, Jianping J; Sikdar, Sinjini S; Lee, Mikyeong M; May-Wilson, Sebastian S; Pirastu, Nicola N; Kentistou, Katherine A KA; Joshi, Peter K PK; Timmers, Paul R H J PRHJ; Williams, Alexander T AT; Free, Robert C RC; Wang, Xueyang X; Morrison, John L JL; Gilliland, Frank D FD; Chen, Zhanghua Z; Wang, Carol A CA; Foong, Rachel E RE; Harris, Sarah E SE; Taylor, Adele A; Redmond, Paul P; Cook, James P JP; Mahajan, Anubha A; Lind, Lars L; Palviainen, Teemu T; Lehtimäki, Terho T; Raitakari, Olli T OT; Kaprio, Jaakko J; Rantanen, Taina T; Pietiläinen, Kirsi H KH; Cox, Simon R SR; Pennell, Craig E CE; Hall, Graham L GL; Gauderman, W James WJ; Brightling, Chris C; Wilson, James F JF; Vasankari, Tuula T; Laitinen, Tarja T; Salomaa, Veikko V; Mook-Kanamori, Dennis O DO; Timpson, Nicholas J NJ; Zeggini, Eleftheria E; Dupuis, Josée J; Hayward, Caroline C; Brumpton, Ben B; Langenberg, Claudia C; Weiss, Stefan S; Homuth, Georg G; Schmidt, Carsten Oliver CO; Probst-Hensch, Nicole N; Jarvelin, Marjo-Riitta MR; Morrison, Alanna C AC; Polasek, Ozren O; Rudan, Igor I; Lee, Joo-Hyeon JH; Sayers, Ian I; Rawlins, Emma L EL; Dudbridge, Frank F; Silverman, Edwin K EK; Strachan, David P DP; Walters, Robin G RG; Morris, Andrew P AP; London, Stephanie J SJ; Cho, Michael H MH; Wain, Louise V LV; Hall, Ian P IP; Tobin, Martin D MD
Publication Date: 2023-03

Variant appearance in text: rs1800888
PubMed Link: 36914875
Variant Present in the following documents:
  • Main text
  • 41588_2023_Article_1314.pdf
  • 41588_2023_1314_MOESM1_ESM.pdf
View BVdb publication page



Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: ADRB2: 491C>T; Thr164Ile
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors.

Cell Reports. Medicine
Álvarez-Prado, Ángel F ÁF; Maas, Roeltje R RR; Soukup, Klara K; Klemm, Florian F; Kornete, Mara M; Krebs, Fanny S FS; Zoete, Vincent V; Berezowska, Sabina S; Brouland, Jean-Philippe JP; Hottinger, Andreas F AF; Daniel, Roy T RT; Hegi, Monika E ME; Joyce, Johanna A JA
Publication Date: 2023-01-17

Variant appearance in text: ADRB2: 491C>T; Thr164Ile
PubMed Link: 36652909
Variant Present in the following documents:
  • mmc8.xlsx, sheet 31
  • mmc3.xlsx, sheet 32
View BVdb publication page



Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity.

Nature Communications
Sandhu, Manbir M; Cho, Aaron A; Ma, Ning N; Mukhaleva, Elizaveta E; Namkung, Yoon Y; Lee, Sangbae S; Ghosh, Soumadwip S; Lee, John H JH; Gloriam, David E DE; Laporte, Stéphane A SA; Babu, M Madan MM; Vaidehi, Nagarajan N
Publication Date: 2022-12-02

Variant appearance in text: rs1800888
PubMed Link: 36460632
Variant Present in the following documents:
  • 41467_2022_34055_MOESM11_ESM.xlsx, sheet 2
View BVdb publication page



The Genetic Factors of the Airway Epithelium Associated with the Pathology of Asthma.

Genes
Ranjbar, Maral M; Whetstone, Christiane E CE; Omer, Hafsa H; Power, Lucy L; Cusack, Ruth P RP; Gauvreau, Gail M GM
Publication Date: 2022-10-15

Variant appearance in text: rs1800888
PubMed Link: 36292755
Variant Present in the following documents:
  • genes-13-01870.pdf
View BVdb publication page



Recent advances in pharmacogenomics research of anti-asthmatic drugs: a narrative review.

Annals Of Translational Medicine
Li, Jie J; Qiu, Chen C
Publication Date: 2022-03

Variant appearance in text: ADRB2: Thr164Ile; rs1800888
PubMed Link: 35434004
Variant Present in the following documents:
  • Main text
  • atm-10-06-369.pdf
View BVdb publication page



Association between beta-2 adrenergic receptor variants and clinical outcomes in children and adolescents with acute asthma.

Einstein (Sao Paulo, Brazil)
Muchão, Fábio Pereira FP; Souza, Andréa Vieira de AV; Souza, Juliana Miguita E JME; Silva Filho, Luiz Vicente Ribeiro Ferreira da LVRFD
Publication Date: 2022

Variant appearance in text: ADRB2: 491C>T; Thr164Ile; rs1800888
PubMed Link: 35352766
Variant Present in the following documents:
  • Main text
  • 2317-6385-eins-20-eAO6412.pdf
View BVdb publication page



Investigating changes in β-adrenergic gene expression (ADRB1 and ADRB2) in Takotsubo (stress) cardiomyopathy syndrome; a pilot study.

Molecular Biology Reports
Tutgun Onrat, Serap S; Dural, İbrahim Etem İE; Yalım, Zafer Z; Onrat, Ersel E
Publication Date: 2021-12

Variant appearance in text: rs1800888
PubMed Link: 34716504
Variant Present in the following documents:
  • Main text
  • 11033_2021_Article_6816.pdf
View BVdb publication page



Genetic and Epigenetic Factors of Takotsubo Syndrome: A Systematic Review.

International Journal Of Molecular Sciences
Ferradini, Valentina V; Vacca, Davide D; Belmonte, Beatrice B; Mango, Ruggiero R; Scola, Letizia L; Novelli, Giuseppe G; Balistreri, Carmela Rita CR; Sangiuolo, Federica F
Publication Date: 2021-09-13

Variant appearance in text: rs1800888
PubMed Link: 34576040
Variant Present in the following documents:
  • Main text
  • ijms-22-09875.pdf
View BVdb publication page



Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine.

Science Advances
Zhou, Yitian Y; Arribas, Gabriel Herras GH; Turku, Ainoleena A; Jürgenson, Tuuli T; Mkrtchian, Souren S; Krebs, Kristi K; Wang, Yi Y; Svobodova, Barbora B; Milani, Lili L; Schulte, Gunnar G; Korabecny, Jan J; Gastaldello, Stefano S; Lauschke, Volker M VM
Publication Date: 2021-09-03

Variant appearance in text: ADRB2: T164I; rs1800888
PubMed Link: 34516913
Variant Present in the following documents:
  • Main text
  • sciadv.abi6856.pdf
View BVdb publication page



Genetic Determinants of Poor Response to Treatment in Severe Asthma.

International Journal Of Molecular Sciences
Figueiredo, Ricardo G RG; Costa, Ryan S RS; Figueiredo, Camila A CA; Cruz, Alvaro A AA
Publication Date: 2021-04-20

Variant appearance in text: ADRB2: Thr164Ile
PubMed Link: 33923891
Variant Present in the following documents:
  • Main text
View BVdb publication page



Identification of Genetic Variants in 65 Obesity Related Genes in a Cohort of Portuguese Obese Individuals.

Genes
Ginete, Catarina C; Serrasqueiro, Bernardo B; Silva-Nunes, José J; Veiga, Luísa L; Brito, Miguel M
Publication Date: 2021-04-19

Variant appearance in text: ADRB2: 491C>T; Thr164Ile; rs1800888
PubMed Link: 33921825
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide association studies of exacerbations in children using long-acting beta2-agonists.

Pediatric Allergy And Immunology : Official Publication Of The European Society Of Pediatric Allergy And Immunology
Slob, Elise M A EMA; Richards, Levi B LB; Vijverberg, Susanne J H SJH; Longo, Cristina C; Koppelman, Gerard H GH; Pijnenburg, Mariëlle W H MWH; Bel, Elisabeth H D EHD; Neerincx, Anne H AH; Herrera Luis, Esther E; Perez-Garcia, Javier J; Tim Chew, Fook F; Yie Sio, Yang Y; Andiappan, Anand K AK; Turner, Steve W SW; Mukhopadhyay, Somnath S; Palmer, Colin N A CNA; Hawcutt, Daniel D; Jorgensen, Andrea L AL; Burchard, Esteban G EG; Hernandez-Pacheco, Natalia N; Pino-Yanes, Maria M; Maitland-van der Zee, Anke H AH
Publication Date: 2021-08

Variant appearance in text: rs1800888
PubMed Link: 33706416
Variant Present in the following documents:
  • Main text
View BVdb publication page



Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Saudi Journal Of Biological Sciences
Aboul-Soud, Mourad A M MAM; Alzahrani, Alhussain J AJ; Mahmoud, Amer A
Publication Date: 2021-01

Variant appearance in text: ADRB2: T164I; rs1800888
PubMed Link: 33424349
Variant Present in the following documents:
  • mmc1.xlsx, sheet 1
View BVdb publication page



How does race and ethnicity effect the precision treatment of asthma?

Expert Review Of Precision Medicine And Drug Development
Zhang, Ellen E; Levin, Albert M AM; Williams, L Keoki LK
Publication Date: 2019

Variant appearance in text: ADRB2: T164I; rs1800888
PubMed Link: 33015363
Variant Present in the following documents:
  • Main text
View BVdb publication page



Analysis of Comprehensive Pharmacogenomic Profiling of VIP Variants Among the Genetically Isolated Chechen Subpopulation from Jordan.

Pharmacogenomics And Personalized Medicine
Al-Eitan, Laith N LN; Rababa'h, Doaa M DM; Hakooz, Nancy M NM; Alghamdi, Mansour A MA; Dajani, Rana B RB
Publication Date: 2020

Variant appearance in text: rs1800888
PubMed Link: 32765042
Variant Present in the following documents:
  • Main text
  • pgpm-13-199.pdf
View BVdb publication page



Unique insights from ClinicalTrials.gov by mining protein mutations and RSids in addition to applying the Human Phenotype Ontology.

Plos One
Alag, Shray S
Publication Date: 2020

Variant appearance in text: rs1800888
PubMed Link: 32459809
Variant Present in the following documents:
  • Main text
  • pone.0233438.pdf
View BVdb publication page



Practical recommendations for the use of beta-blockers in chronic obstructive pulmonary disease.

Expert Review Of Respiratory Medicine
Wade, Chad C; Wells, J Michael JM
Publication Date: 2020-07

Variant appearance in text: ADRB2: Thr164Ile
PubMed Link: 32250198
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic Polymorphisms of Pharmacogenes among the Genetically Isolated Circassian Subpopulation from Jordan.

Journal Of Personalized Medicine
Al-Eitan, Laith N LN; Rababa'h, Doaa M DM; Hakooz, Nancy M NM; Alghamdi, Mansour A MA; Dajani, Rana B RB
Publication Date: 2020-01-06

Variant appearance in text: rs1800888
PubMed Link: 31935801
Variant Present in the following documents:
  • Main text
  • jpm-10-00002.pdf
View BVdb publication page



Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis.

American Journal Of Respiratory And Critical Care Medicine
Allen, Richard J RJ; Guillen-Guio, Beatriz B; Oldham, Justin M JM; Ma, Shwu-Fan SF; Dressen, Amy A; Paynton, Megan L ML; Kraven, Luke M LM; Obeidat, Ma'en M; Li, Xuan X; Ng, Michael M; Braybrooke, Rebecca R; Molina-Molina, Maria M; Hobbs, Brian D BD; Putman, Rachel K RK; Sakornsakolpat, Phuwanat P; Booth, Helen L HL; Fahy, William A WA; Hart, Simon P SP; Hill, Mike R MR; Hirani, Nik N; Hubbard, Richard B RB; McAnulty, Robin J RJ; Millar, Ann B AB; Navaratnam, Vidyia V; Oballa, Eunice E; Parfrey, Helen H; Saini, Gauri G; Whyte, Moira K B MKB; Zhang, Yingze Y; Kaminski, Naftali N; Adegunsoye, Ayodeji A; Strek, Mary E ME; Neighbors, Margaret M; Sheng, Xuting R XR; Gudmundsson, Gunnar G; Gudnason, Vilmundur V; Hatabu, Hiroto H; Lederer, David J DJ; Manichaikul, Ani A; Newell, John D JD; O'Connor, George T GT; Ortega, Victor E VE; Xu, Hanfei H; Fingerlin, Tasha E TE; Bossé, Yohan Y; Hao, Ke K; Joubert, Philippe P; Nickle, David C DC; Sin, Don D DD; Timens, Wim W; Furniss, Dominic D; Morris, Andrew P AP; Zondervan, Krina T KT; Hall, Ian P IP; Sayers, Ian I; Tobin, Martin D MD; Maher, Toby M TM; Cho, Michael H MH; Hunninghake, Gary M GM; Schwartz, David A DA; Yaspan, Brian L BL; Molyneaux, Philip L PL; Flores, Carlos C; Noth, Imre I; Jenkins, R Gisli RG; Wain, Louise V LV
Publication Date: 2020-03-01

Variant appearance in text: rs1800888
PubMed Link: 31710517
Variant Present in the following documents:
  • rccm.201905-1017OC_allen_data_supplement.pdf
View BVdb publication page



β2-Adrenergic Receptor (ADRB2) Gene Polymorphisms and Risk of COPD Exacerbations: The Rotterdam Study.

Journal Of Clinical Medicine
Karimi, Leila L; Lahousse, Lies L; Ghanbari, Mohsen M; Terzikhan, Natalie N; Uitterlinden, André G AG; van der Lei, Johan J; Brusselle, Guy G GG; Stricker, Bruno H BH; Verhamme, Katia M C KMC
Publication Date: 2019-11-01

Variant appearance in text: rs1800888
PubMed Link: 31683975
Variant Present in the following documents:
  • Main text
View BVdb publication page



Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.

Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
Publication Date: 2019-10-09

Variant appearance in text: ADRB2: T164I; rs1800888
PubMed Link: 31597922
Variant Present in the following documents:
  • 41598_2019_50891_MOESM7_ESM.xlsx, sheet 1
  • 41598_2019_50891_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Dissecting genetic factors affecting phenylephrine infusion rates during anesthesia: a genome-wide association study employing EHR data.

Bmc Medicine
Zhang, Yanfei Y; Poler, S Mark SM; Li, Jiang J; Abedi, Vida V; Pendergrass, Sarah A SA; Williams, Marc S MS; Lee, Ming Ta Michael MTM
Publication Date: 2019-08-28

Variant appearance in text: ADRB2: Thr164Ile; rs1800888
PubMed Link: 31455332
Variant Present in the following documents:
  • Main text
  • 12916_2019_Article_1405.pdf
View BVdb publication page



Evolving neoantigen profiles in colorectal cancers with DNA repair defects.

Genome Medicine
Rospo, Giuseppe G; Lorenzato, Annalisa A; Amirouchene-Angelozzi, Nabil N; Magrì, Alessandro A; Cancelliere, Carlotta C; Corti, Giorgio G; Negrino, Carola C; Amodio, Vito V; Montone, Monica M; Bartolini, Alice A; Barault, Ludovic L; Novara, Luca L; Isella, Claudio C; Medico, Enzo E; Bertotti, Andrea A; Trusolino, Livio L; Germano, Giovanni G; Di Nicolantonio, Federica F; Bardelli, Alberto A
Publication Date: 2019-06-28

Variant appearance in text: ADRB2: T164I
PubMed Link: 31253177
Variant Present in the following documents:
  • 13073_2019_654_MOESM2_ESM.xlsx, sheet 16
  • 13073_2019_654_MOESM2_ESM.xlsx, sheet 20
View BVdb publication page



Pharmacogenetic Factors Affecting Asthma Treatment Response. Potential Implications for Drug Therapy.

Frontiers In Pharmacology
García-Menaya, Jesús Miguel JM; Cordobés-Durán, Concepción C; García-Martín, Elena E; Agúndez, José A G JAG
Publication Date: 2019

Variant appearance in text: ADRB2: T164I; rs1800888
PubMed Link: 31178722
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeted next generation sequencing as a tool for precision medicine.

Bmc Medical Genomics
Gulilat, Markus M; Lamb, Tyler T; Teft, Wendy A WA; Wang, Jian J; Dron, Jacqueline S JS; Robinson, John F JF; Tirona, Rommel G RG; Hegele, Robert A RA; Kim, Richard B RB; Schwarz, Ute I UI
Publication Date: 2019-06-03

Variant appearance in text: ADRB2: T164I; rs1800888
PubMed Link: 31159795
Variant Present in the following documents:
  • 12920_2019_527_MOESM1_ESM.xlsx, sheet 6
View BVdb publication page



Variants in BMI-Associated Genes and Adrenergic Genes are not Associated with Gestational Weight Trajectory.

Obesity (Silver Spring, Md.)
Kawai, Vivian K VK; Nwosu, Samuel K SK; Kurnik, Daniel D; Harrell, Frank E FE; Stein, C Michael CM
Publication Date: 2019-07

Variant appearance in text: rs1800888
PubMed Link: 31116007
Variant Present in the following documents:
  • Main text
View BVdb publication page



β2 -Adrenergic Receptor Gene Affects the Heart Rate Response of β-Blockers: Evidence From 3 Clinical Studies.

Journal Of Clinical Pharmacology
Shahin, Mohamed H MH; Rouby, Nihal El NE; Conrado, Daniela J DJ; Gonzalez, Daniel D; Gong, Yan Y; Lobmeyer, Maximilian T MT; Beitelshees, Amber L AL; Boerwinkle, Eric E; Gums, John G JG; Chapman, Arlene A; Turner, Stephen T ST; Pepine, Carl J CJ; Cooper-DeHoff, Rhonda M RM; Johnson, Julie A JA
Publication Date: 2019-11

Variant appearance in text: rs1800888
PubMed Link: 31090079
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic analysis of pharmacogenomic VIP variants in the Blang population from Yunnan Province of China.

Molecular Genetics & Genomic Medicine
Zhang, Chan C; Guo, Weiwei W; Cheng, Yujing Y; Li, Qi Q; Yang, Xin X; Dai, Run R; Zhu, Linhao L; Chen, Wanlu W
Publication Date: 2019-05

Variant appearance in text: ADRB2: Thr164Ile; rs1800888
PubMed Link: 30955239
Variant Present in the following documents:
  • Main text
  • MGG3-7-e574.pdf
View BVdb publication page



Beta2-Adrenergic Receptor Polymorphisms and Haplotypes Associate With Chronic Pain in Sickle Cell Disease.

Frontiers In Pharmacology
Jhun, Ellie H EH; Sadhu, Nilanjana N; Hu, Xiaoyu X; Yao, Yingwei Y; He, Ying Y; Wilkie, Diana J DJ; Molokie, Robert E RE; Wang, Zaijie Jim ZJ
Publication Date: 2019

Variant appearance in text: rs1800888
PubMed Link: 30837870
Variant Present in the following documents:
  • Main text
View BVdb publication page



New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Nature Genetics
Shrine, Nick N; Guyatt, Anna L AL; Erzurumluoglu, A Mesut AM; Jackson, Victoria E VE; Hobbs, Brian D BD; Melbourne, Carl A CA; Batini, Chiara C; Fawcett, Katherine A KA; Song, Kijoung K; Sakornsakolpat, Phuwanat P; Li, Xingnan X; Boxall, Ruth R; Reeve, Nicola F NF; Obeidat, Ma'en M; Zhao, Jing Hua JH; Wielscher, Matthias M; Weiss, Stefan S; Kentistou, Katherine A KA; Cook, James P JP; Sun, Benjamin B BB; Zhou, Jian J; Hui, Jennie J; Karrasch, Stefan S; Imboden, Medea M; Harris, Sarah E SE; Marten, Jonathan J; Enroth, Stefan S; Kerr, Shona M SM; Surakka, Ida I; Vitart, Veronique V; Lehtimäki, Terho T; Allen, Richard J RJ; Bakke, Per S PS; Beaty, Terri H TH; Bleecker, Eugene R ER; Bossé, Yohan Y; Brandsma, Corry-Anke CA; Chen, Zhengming Z; Crapo, James D JD; Danesh, John J; DeMeo, Dawn L DL; Dudbridge, Frank F; Ewert, Ralf R; Gieger, Christian C; Gulsvik, Amund A; Hansell, Anna L AL; Hao, Ke K; Hoffman, Joshua D JD; Hokanson, John E JE; Homuth, Georg G; Joshi, Peter K PK; Joubert, Philippe P; Langenberg, Claudia C; Li, Xuan X; Li, Liming L; Lin, Kuang K; Lind, Lars L; Locantore, Nicholas N; Luan, Jian'an J; Mahajan, Anubha A; Maranville, Joseph C JC; Murray, Alison A; Nickle, David C DC; Packer, Richard R; Parker, Margaret M MM; Paynton, Megan L ML; Porteous, David J DJ; Prokopenko, Dmitry D; Qiao, Dandi D; Rawal, Rajesh R; Runz, Heiko H; Sayers, Ian I; Sin, Don D DD; Smith, Blair H BH; Soler Artigas, María M; Sparrow, David D; Tal-Singer, Ruth R; Timmers, Paul R H J PRHJ; Van den Berge, Maarten M; Whittaker, John C JC; Woodruff, Prescott G PG; Yerges-Armstrong, Laura M LM; Troyanskaya, Olga G OG; Raitakari, Olli T OT; Kähönen, Mika M; Polašek, Ozren O; Gyllensten, Ulf U; Rudan, Igor I; Deary, Ian J IJ; Probst-Hensch, Nicole M NM; Schulz, Holger H; James, Alan L AL; Wilson, James F JF; Stubbe, Beate B; Zeggini, Eleftheria E; Jarvelin, Marjo-Riitta MR; Wareham, Nick N; Silverman, Edwin K EK; Hayward, Caroline C; Morris, Andrew P AP; Butterworth, Adam S AS; Scott, Robert A RA; Walters, Robin G RG; Meyers, Deborah A DA; Cho, Michael H MH; Strachan, David P DP; Hall, Ian P IP; Tobin, Martin D MD; Wain, Louise V LV; ,
Publication Date: 2019-03

Variant appearance in text: rs1800888
PubMed Link: 30804560
Variant Present in the following documents:
  • Main text
  • nihms-1514965.pdf
View BVdb publication page



Association of genetic variants with level of asthma control in the Arab population.

Journal Of Asthma And Allergy
Almomani, Basima A BA; Al-Eitan, Laith N LN; Al-Sawalha, Nour A NA; Samrah, Shaher M SM; Al-Quasmi, Mohammed N MN
Publication Date: 2019

Variant appearance in text: ADRB2: Thr164Ile; rs1800888
PubMed Link: 30774389
Variant Present in the following documents:
  • Main text
View BVdb publication page



β2-Adrenergic Receptor Gene Polymorphisms Are Associated with Cardiovascular Events But not All-Cause Mortality in Coronary Artery Disease Patients: A Meta-Analysis of Prospective Studies.

Genetic Testing And Molecular Biomarkers
Li, Yanrong Y; Yuan, Huiping H; Sun, Liang L; Zhou, Qi Q; Yang, Fan F; Yang, Ze Z; Liu, Deping D
Publication Date: 2019-02

Variant appearance in text: ADRB2: Thr164Ile; rs1800888
PubMed Link: 30668166
Variant Present in the following documents:
  • Main text
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Assessment of coding region variants in Kuwaiti population: implications for medical genetics and population genomics.

Scientific Reports
John, Sumi Elsa SE; Antony, Dinu D; Eaaswarkhanth, Muthukrishnan M; Hebbar, Prashantha P; Channanath, Arshad Mohamed AM; Thomas, Daisy D; Devarajan, Sriraman S; Tuomilehto, Jaakko J; Al-Mulla, Fahd F; Alsmadi, Osama O; Thanaraj, Thangavel Alphonse TA
Publication Date: 2018-11-08

Variant appearance in text: ADRB2: 491C>T; Thr164Ile; rs1800888
PubMed Link: 30409984
Variant Present in the following documents:
  • Main text
  • 41598_2018_Article_34815.pdf
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TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw.

Nature Communications
Gomes, Carolina Cavalieri CC; Gayden, Tenzin T; Bajic, Andrea A; Harraz, Osama F OF; Pratt, Jonathan J; Nikbakht, Hamid H; Bareke, Eric E; Diniz, Marina Gonçalves MG; Castro, Wagner Henriques WH; St-Onge, Pascal P; Sinnett, Daniel D; Han, HyeRim H; Rivera, Barbara B; Mikael, Leonie G LG; De Jay, Nicolas N; Kleinman, Claudia L CL; Valera, Elvis Terci ET; Bassenden, Angelia V AV; Berghuis, Albert M AM; Majewski, Jacek J; Nelson, Mark T MT; Gomez, Ricardo Santiago RS; Jabado, Nada N
Publication Date: 2018-11-01

Variant appearance in text: ADRB2: T164I; rs1800888
PubMed Link: 30385747
Variant Present in the following documents:
  • 41467_2018_6690_MOESM8_ESM.xlsx, sheet 1
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ADRB2 polymorphism Arg16Gly modifies the natural outcome of heart failure and dictates therapeutic response to β-blockers in patients with heart failure.

Cell Discovery
Huang, Jin J; Li, Chenze C; Song, Ying Y; Fan, Xiaohan X; You, Ling L; Tan, Lun L; Xiao, Lei L; Li, Qing Q; Ruan, Guoran G; Hu, Senlin S; Cui, Wei W; Li, Zongzhe Z; Ni, Li L; Chen, Chen C; Woo, Anthony Yiu-Ho AY; Xiao, Rui-Ping RP; Wang, Dao Wen DW
Publication Date: 2018

Variant appearance in text: ADRB2: Thr164Ile
PubMed Link: 30374408
Variant Present in the following documents:
  • Main text
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Development of an AmpliSeqTM Panel for Next-Generation Sequencing of a Set of Genetic Predictors of Persisting Pain.

Frontiers In Pharmacology
Kringel, Dario D; Kaunisto, Mari A MA; Lippmann, Catharina C; Kalso, Eija E; Lötsch, Jörn J
Publication Date: 2018

Variant appearance in text: rs1800888
PubMed Link: 30283335
Variant Present in the following documents:
  • Main text
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Genetic polymorphisms of pharmacogenomic VIP variants in the Lisu population of southwestern China: A cohort study.

Medicine
Li, Bin B; Wang, Li L; Lei, Lingyu L; Zhang, Mingxiang M; Niu, Fanglin F; Chen, Peng P; Jin, Tianbo T
Publication Date: 2018-09

Variant appearance in text: ADRB2: Thr164Ile; rs1800888
PubMed Link: 30235667
Variant Present in the following documents:
  • medi-97-e12231.pdf
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Genetic polymorphisms in very important pharmacogenomic variants in the Zhuang ethnic group of Southwestern China: A cohort study in the Zhuang population.

Medicine
Li, Jing J; Guo, Chenghao C; Yan, Mengdan M; Niu, Fanglin F; Chen, Peng P; Li, Bin B; Jin, Tianbo T
Publication Date: 2018-04

Variant appearance in text: ADRB2: Thr164Ile; rs1800888
PubMed Link: 29703042
Variant Present in the following documents:
  • medi-97-e0559.pdf
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Genetic variation in human drug-related genes.

Genome Medicine
Schärfe, Charlotta Pauline Irmgard CPI; Tremmel, Roman R; Schwab, Matthias M; Kohlbacher, Oliver O; Marks, Debora Susan DS
Publication Date: 2017-12-22

Variant appearance in text: ADRB2: T164I; rs1800888
PubMed Link: 29273096
Variant Present in the following documents:
  • Main text
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Association between ß2-adrenergic receptor gene polymorphisms and adverse events of ritodrine in the treatment of preterm labor: a prospective observational study.

Bmc Genetics
Chung, Jee Eun JE; Choi, Soo An SA; Hwang, Han Sung HS; Park, Jin Young JY; Lee, Kyung Eun KE; Yee, Jeong J; Kim, Young Ju YJ; Gwak, Hye Sun HS
Publication Date: 2017-11-13

Variant appearance in text: ADRB2: Thr164Ile; rs1800888
PubMed Link: 29132297
Variant Present in the following documents:
  • Main text
  • 12863_2017_Article_565.pdf
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Molecular dynamic simulations reveal suboptimal binding of salbutamol in T164I variant of β2 adrenergic receptor.

Plos One
Bandaru, Srinivas S; Alvala, Mallika M; Nayarisseri, Anuraj A; Sharda, Saphy S; Goud, Himshikha H; Mundluru, Hema Prasad HP; Singh, Sanjeev Kumar SK
Publication Date: 2017

Variant appearance in text: ADRB2: T164I
PubMed Link: 29053759
Variant Present in the following documents:
  • Main text
  • pone.0186666.pdf
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Personalized management of asthma exacerbations: lessons from genetic studies.

Expert Review Of Precision Medicine And Drug Development
Wang, Alberta L AL; Tantisira, Kelan G KG
Publication Date: 2016

Variant appearance in text: ADRB2: Thr164Ile
PubMed Link: 29051920
Variant Present in the following documents:
  • Main text
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tmVar 2.0: integrating genomic variant information from literature with dbSNP and ClinVar for precision medicine.

Bioinformatics (Oxford, England)
Wei, Chih-Hsuan CH; Phan, Lon L; Feltz, Juliana J; Maiti, Rama R; Hefferon, Tim T; Lu, Zhiyong Z
Publication Date: 2018-01-01

Variant appearance in text: rs1800888
PubMed Link: 28968638
Variant Present in the following documents:
  • Main text
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Continuity and Admixture in the Last Five Millennia of Levantine History from Ancient Canaanite and Present-Day Lebanese Genome Sequences.

American Journal Of Human Genetics
Haber, Marc M; Doumet-Serhal, Claude C; Scheib, Christiana C; Xue, Yali Y; Danecek, Petr P; Mezzavilla, Massimo M; Youhanna, Sonia S; Martiniano, Rui R; Prado-Martinez, Javier J; Szpak, Michał M; Matisoo-Smith, Elizabeth E; Schutkowski, Holger H; Mikulski, Richard R; Zalloua, Pierre P; Kivisild, Toomas T; Tyler-Smith, Chris C
Publication Date: 2017-08-03

Variant appearance in text: rs1800888
PubMed Link: 28757201
Variant Present in the following documents:
  • mmc1.pdf
  • mmc2.pdf
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Benchmarking of Whole Exome Sequencing and Ad Hoc Designed Panels for Genetic Testing of Hereditary Cancer.

Scientific Reports
Feliubadaló, Lídia L; Tonda, Raúl R; Gausachs, Mireia M; Trotta, Jean-Rémi JR; Castellanos, Elisabeth E; López-Doriga, Adriana A; Teulé, Àlex À; Tornero, Eva E; Del Valle, Jesús J; Gel, Bernat B; Gut, Marta M; Pineda, Marta M; González, Sara S; Menéndez, Mireia M; Navarro, Matilde M; Capellá, Gabriel G; Gut, Ivo I; Serra, Eduard E; Brunet, Joan J; Beltran, Sergi S; Lázaro, Conxi C
Publication Date: 2017-01-04

Variant appearance in text: ADRB2: 491C>T; Thr164Ile
PubMed Link: 28050010
Variant Present in the following documents:
  • srep37984-s2.xls, sheet 1
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β2 Agonists.

Handbook Of Experimental Pharmacology
Billington, Charlotte K CK; Penn, Raymond B RB; Hall, Ian P IP
Publication Date: 2017

Variant appearance in text: ADRB2: Thr164Ile
PubMed Link: 27878470
Variant Present in the following documents:
  • Main text
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Pharmacogenetics and Pharmacotherapy of Military Personnel Suffering from Post-traumatic Stress Disorder.

Current Neuropharmacology
Naß, Janine J; Efferth, Thomas T
Publication Date: 2017

Variant appearance in text: rs1800888
PubMed Link: 27834145
Variant Present in the following documents:
  • Main text
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Proteome-wide Structural Analysis of PTM Hotspots Reveals Regulatory Elements Predicted to Impact Biological Function and Disease.

Molecular & Cellular Proteomics : Mcp
Torres, Matthew P MP; Dewhurst, Henry H; Sundararaman, Niveda N
Publication Date: 2016-11

Variant appearance in text: ADRB2: 491C>T
PubMed Link: 27697855
Variant Present in the following documents:
  • 10.1074_M116.062331_mcp.M116.062331-3.xlsx, sheet 5
View BVdb publication page