Impact of Functional Polymorphisms on Drug Survival of Biological Therapies in Patients with Moderate-to-Severe Psoriasis.
International Journal Of Molecular Sciences
Membrive-Jiménez, Cristina C; Pérez-Ramírez, Cristina C; Arias-Santiago, Salvador S; Richetta, Antonio Giovanni AG; Ottini, Laura L; Pineda-Lancheros, Laura Elena LE; Ramírez-Tortosa, Maria Del Carmen MDC; Jiménez-Morales, Alberto A
Assessment of the Potential Role of Selected Single Nucleotide Polymorphisms (SNPs) of Genes Related to the Functioning of Regulatory T Cells in the Pathogenesis of Psoriasis.
International Journal Of Molecular Sciences
Purzycka-Bohdan, Dorota D; Nedoszytko, Bogusław B; Sobalska-Kwapis, Marta M; Zabłotna, Monika M; Żmijewski, Michał A MA; Wierzbicka, Justyna J; Gleń, Jolanta J; Strapagiel, Dominik D; Szczerkowska-Dobosz, Aneta A; Nowicki, Roman J RJ
Biomarkers of systemic treatment response in people with psoriasis: a scoping review.
The British Journal Of Dermatology
Corbett, Mark M; Ramessur, Ravi R; Marshall, David D; Acencio, Marcio L ML; Ostaszewski, Marek M; Barbosa, Ines A IA; Dand, Nick N; Di Meglio, Paola P; Haddad, Salma S; Jensen, Andreas H M AHM; Koopmann, Witte W; Mahil, Satveer K SK; Rahmatulla, Seher S; Rastrick, Joe J; Saklatvala, Jake J; Weidinger, Stephan S; Wright, Kath K; Eyerich, Kilian K; Barker, Jonathan N JN; Ndlovu, Matladi M; Conrad, Curdin C; Skov, Lone L; Smith, Catherine H CH; ,
Ustekinumab Dosing Individualization in Crohn's Disease Guided by a Population Pharmacokinetic-Pharmacodynamic Model.
Pharmaceutics
Aguiar Zdovc, Jurij J; Hanžel, Jurij J; Kurent, Tina T; Sever, Nejc N; Koželj, Matic M; Smrekar, Nataša N; Novak, Gregor G; Štabuc, Borut B; Dreesen, Erwin E; Thomas, Debby D; Vovk, Tomaž T; Ostanek, Barbara B; Drobne, David D; Grabnar, Iztok I
Influence of Genetic Polymorphisms on Response to Biologics in Moderate-to-Severe Psoriasis.
Journal Of Personalized Medicine
Membrive Jiménez, Cristina C; Pérez Ramírez, Cristina C; Sánchez Martín, Almudena A; Vieira Maroun, Sayleth S; Arias Santiago, Salvador Antonio SA; Ramírez Tortosa, María Del Carmen MDC; Jiménez Morales, Alberto A
Advancing drug discovery using the power of the human genome.
The Journal Of Pathology
Heilbron, Karl K; Mozaffari, Sahar V SV; Vacic, Vladimir V; Yue, Peng P; Wang, Wei W; Shi, Jingchunzi J; Jubb, Adrian M AM; Pitts, Steven J SJ; Wang, Xin X
Advancing drug discovery using the power of the human genome.
The Journal Of Pathology
Heilbron, Karl K; Mozaffari, Sahar V SV; Vacic, Vladimir V; Yue, Peng P; Wang, Wei W; Shi, Jingchunzi J; Jubb, Adrian M AM; Pitts, Steven J SJ; Wang, Xin X
Interaction between host genes and Mycobacterium tuberculosis lineage can affect tuberculosis severity: Evidence for coevolution?
Plos Genetics
McHenry, Michael L ML; Bartlett, Jacquelaine J; Igo, Robert P RP; Wampande, Eddie M EM; Benchek, Penelope P; Mayanja-Kizza, Harriet H; Fluegge, Kyle K; Hall, Noemi B NB; Gagneux, Sebastien S; Tishkoff, Sarah A SA; Wejse, Christian C; Sirugo, Giorgio G; Boom, W Henry WH; Joloba, Moses M; Williams, Scott M SM; Stein, Catherine M CM
Population-Wide Genetic Risk Prediction of Complex Diseases: A Pilot Feasibility Study in Macau Population for Precision Public Healthcare Planning.
Scientific Reports
Tsui, Nancy B Y NBY; Cheng, Gregory G; Chung, Teresa T; Lam, Christopher W K CWK; Yee, Anita A; Chung, Peter K C PKC; Kwan, Tsz-Ki TK; Ko, Elaine E; He, Daihai D; Wong, Wing-Tak WT; Lau, Johnson Y N JYN; Lau, Lok Ting LT; Fok, Manson M
Associations between SNPs and immune-related circulating proteins in schizophrenia.
Scientific Reports
Chan, Man K MK; Cooper, Jason D JD; Heilmann-Heimbach, Stefanie S; Frank, Josef J; Witt, Stephanie H SH; Nöthen, Markus M MM; Steiner, Johann J; Rietschel, Marcella M; Bahn, Sabine S
Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling.
Human Molecular Genetics
Dand, Nick N; Mucha, Sören S; Tsoi, Lam C LC; Mahil, Satveer K SK; Stuart, Philip E PE; Arnold, Andreas A; Baurecht, Hansjörg H; Burden, A David AD; Callis Duffin, Kristina K; Chandran, Vinod V; Curtis, Charles J CJ; Das, Sayantan S; Ellinghaus, David D; Ellinghaus, Eva E; Enerback, Charlotta C; Esko, Tõnu T; Gladman, Dafna D DD; Griffiths, Christopher E M CEM; Gudjonsson, Johann E JE; Hoffman, Per P; Homuth, Georg G; Hüffmeier, Ulrike U; Krueger, Gerald G GG; Laudes, Matthias M; Lee, Sang Hyuck SH; Lieb, Wolfgang W; Lim, Henry W HW; Löhr, Sabine S; Mrowietz, Ulrich U; Müller-Nurayid, Martina M; Nöthen, Markus M; Peters, Annette A; Rahman, Proton P; Reis, André A; Reynolds, Nick J NJ; Rodriguez, Elke E; Schmidt, Carsten O CO; Spain, Sarah L SL; Strauch, Konstantin K; Tejasvi, Trilokraj T; Voorhees, John J JJ; Warren, Richard B RB; Weichenthal, Michael M; Weidinger, Stephan S; Zawistowski, Matthew M; Nair, Rajan P RP; Capon, Francesca F; Smith, Catherine H CH; Trembath, Richard C RC; Abecasis, Goncalo R GR; Elder, James T JT; Franke, Andre A; Simpson, Michael A MA; Barker, Jonathan N JN
The association between 38 previously reported polymorphisms and psoriasis in a Polish population: High predicative accuracy of a genetic risk score combining 16 loci.
Plos One
Kisiel, Bartłomiej B; Kisiel, Katarzyna K; Szymański, Konrad K; Mackiewicz, Wojciech W; Biało-Wójcicka, Ewelina E; Uczniak, Sebastian S; Fogtman, Anna A; Iwanicka-Nowicka, Roksana R; Koblowska, Marta M; Kossowska, Helena H; Placha, Grzegorz G; Sykulski, Maciej M; Bachta, Artur A; Tłustochowicz, Witold W; Płoski, Rafał R; Kaszuba, Andrzej A
Inflammatory pathway genes associated with inter-individual variability in the trajectories of morning and evening fatigue in patients receiving chemotherapy.
Cytokine
Wright, Fay F; Hammer, Marilyn M; Paul, Steven M SM; Aouizerat, Bradley E BE; Kober, Kord M KM; Conley, Yvette P YP; Cooper, Bruce A BA; Dunn, Laura B LB; Levine, Jon D JD; DEramo Melkus, Gail G; Miaskowski, Christine C
Candidate gene polymorphisms and risk of psoriasis: A pilot study.
Experimental And Therapeutic Medicine
Villarreal-Martínez, Alejandra A; Gallardo-Blanco, Hugo H; Cerda-Flores, Ricardo R; Torres-Muñoz, Iris I; Gómez-Flores, Minerva M; Salas-Alanís, Julio J; Ocampo-Candiani, Jorge J; Martínez-Garza, Laura L
A Locus at 5q33.3 Confers Resistance to Tuberculosis in Highly Susceptible Individuals.
American Journal Of Human Genetics
Sobota, Rafal S RS; Stein, Catherine M CM; Kodaman, Nuri N; Scheinfeldt, Laura B LB; Maro, Isaac I; Wieland-Alter, Wendy W; Igo, Robert P RP; Magohe, Albert A; Malone, LaShaunda L LL; Chervenak, Keith K; Hall, Noemi B NB; Modongo, Chawangwa C; Zetola, Nicola N; Matee, Mecky M; Joloba, Moses M; Froment, Alain A; Nyambo, Thomas B TB; Moore, Jason H JH; Scott, William K WK; Lahey, Timothy T; Boom, W Henry WH; von Reyn, C Fordham CF; Tishkoff, Sarah A SA; Sirugo, Giorgio G; Williams, Scott M SM
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
American Journal Of Human Genetics
Stuart, Philip E PE; Nair, Rajan P RP; Tsoi, Lam C LC; Tejasvi, Trilokraj T; Das, Sayantan S; Kang, Hyun Min HM; Ellinghaus, Eva E; Chandran, Vinod V; Callis-Duffin, Kristina K; Ike, Robert R; Li, Yanming Y; Wen, Xiaoquan X; Enerbäck, Charlotta C; Gudjonsson, Johann E JE; Kõks, Sulev S; Kingo, Külli K; Esko, Tõnu T; Mrowietz, Ulrich U; Reis, Andre A; Wichmann, H Erich HE; Gieger, Christian C; Hoffmann, Per P; Nöthen, Markus M MM; Winkelmann, Juliane J; Kunz, Manfred M; Moreta, Elvia G EG; Mease, Philip J PJ; Ritchlin, Christopher T CT; Bowcock, Anne M AM; Krueger, Gerald G GG; Lim, Henry W HW; Weidinger, Stephan S; Weichenthal, Michael M; Voorhees, John J JJ; Rahman, Proton P; Gregersen, Peter K PK; Franke, Andre A; Gladman, Dafna D DD; Abecasis, Gonçalo R GR; Elder, James T JT
Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms.
American Journal Of Human Genetics
Baurecht, Hansjörg H; Hotze, Melanie M; Brand, Stephan S; Büning, Carsten C; Cormican, Paul P; Corvin, Aiden A; Ellinghaus, David D; Ellinghaus, Eva E; Esparza-Gordillo, Jorge J; Fölster-Holst, Regina R; Franke, Andre A; Gieger, Christian C; Hubner, Norbert N; Illig, Thomas T; Irvine, Alan D AD; Kabesch, Michael M; Lee, Young A E YA; Lieb, Wolfgang W; Marenholz, Ingo I; McLean, W H Irwin WH; Morris, Derek W DW; Mrowietz, Ulrich U; Nair, Rajan R; Nöthen, Markus M MM; Novak, Natalija N; O'Regan, Grainne M GM; , ; Schreiber, Stefan S; Smith, Catherine C; Strauch, Konstantin K; Stuart, Philip E PE; Trembath, Richard R; Tsoi, Lam C LC; Weichenthal, Michael M; Barker, Jonathan J; Elder, James T JT; Weidinger, Stephan S; Cordell, Heather J HJ; Brown, Sara J SJ
Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus.
Gastroenterology
Palles, Claire C; Chegwidden, Laura L; Li, Xinzhong X; Findlay, John M JM; Farnham, Garry G; Castro Giner, Francesc F; Peppelenbosch, Maikel P MP; Kovac, Michal M; Adams, Claire L CL; Prenen, Hans H; Briggs, Sarah S; Harrison, Rebecca R; Sanders, Scott S; MacDonald, David D; Haigh, Chris C; Tucker, Art A; Love, Sharon S; Nanji, Manoj M; deCaestecker, John J; Ferry, David D; Rathbone, Barrie B; Hapeshi, Julie J; Barr, Hugh H; Moayyedi, Paul P; Watson, Peter P; Zietek, Barbara B; Maroo, Neera N; Gay, Laura L; Underwood, Tim T; Boulter, Lisa L; McMurtry, Hugh H; Monk, David D; Patel, Praful P; Ragunath, Krish K; Al Dulaimi, David D; Murray, Iain I; Koss, Konrad K; Veitch, Andrew A; Trudgill, Nigel N; Nwokolo, Chuka C; Rembacken, Bjorn B; Atherfold, Paul P; Green, Elaine E; Ang, Yeng Y; Kuipers, Ernst J EJ; Chow, Wu W; Paterson, Stuart S; Kadri, Sudarshan S; Beales, Ian I; Grimley, Charles C; Mullins, Paul P; Beckett, Conrad C; Farrant, Mark M; Dixon, Andrew A; Kelly, Sean S; Johnson, Matthew M; Wajed, Shahjehan S; Dhar, Anjan A; Sawyer, Elinor E; Roylance, Rebecca R; Onstad, Lynn L; Gammon, Marilie D MD; Corley, Douglas A DA; Shaheen, Nicholas J NJ; Bird, Nigel C NC; Hardie, Laura J LJ; Reid, Brian J BJ; Ye, Weimin W; Liu, Geoffrey G; Romero, Yvonne Y; Bernstein, Leslie L; Wu, Anna H AH; Casson, Alan G AG; Fitzgerald, Rebecca R; Whiteman, David C DC; Risch, Harvey A HA; Levine, David M DM; Vaughan, Tom L TL; Verhaar, Auke P AP; van den Brande, Jan J; Toxopeus, Eelke L EL; Spaander, Manon C MC; Wijnhoven, Bas P L BP; van der Laan, Luc J W LJ; Krishnadath, Kausilia K; Wijmenga, Cisca C; Trynka, Gosia G; McManus, Ross R; Reynolds, John V JV; O'Sullivan, Jacintha J; MacMathuna, Padraic P; McGarrigle, Sarah A SA; Kelleher, Dermot D; Vermeire, Severine S; Cleynen, Isabelle I; Bisschops, Raf R; Tomlinson, Ian I; Jankowski, Janusz J
The role of 39 psoriasis risk variants on age of psoriasis onset.
Isrn Dermatology
Lu, Yingchang Y; Kane, Sinae S; Chen, Haoyan H; Leon, Argentina A; Levin, Ethan E; Nguyen, Tien T; Debbaneh, Maya M; Millsop, Jillian W JW; Gupta, Rishu R; Huynh, Monica M; Butler, Daniel D; Cordoro, Kelly K; Liao, Wilson W
A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.
Human Molecular Genetics
Weidinger, Stephan S; Willis-Owen, Saffron A G SA; Kamatani, Yoichiro Y; Baurecht, Hansjörg H; Morar, Nilesh N; Liang, Liming L; Edser, Pauline P; Street, Teresa T; Rodriguez, Elke E; O'Regan, Grainne M GM; Beattie, Paula P; Fölster-Holst, Regina R; Franke, Andre A; Novak, Natalija N; Fahy, Caoimhe M CM; Winge, Mårten C G MC; Kabesch, Michael M; Illig, Thomas T; Heath, Simon S; Söderhäll, Cilla C; Melén, Erik E; Pershagen, Göran G; Kere, Juha J; Bradley, Maria M; Lieden, Agne A; Nordenskjold, Magnus M; Harper, John I JI; McLean, W H Irwin WH; Brown, Sara J SJ; Cookson, William O C WO; Lathrop, G Mark GM; Irvine, Alan D AD; Moffatt, Miriam F MF
Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations?
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
Nature Genetics
, ; Strange, Amy A; Capon, Francesca F; Spencer, Chris C A CC; Knight, Jo J; Weale, Michael E ME; Allen, Michael H MH; Barton, Anne A; Band, Gavin G; Bellenguez, Céline C; Bergboer, Judith G M JG; Blackwell, Jenefer M JM; Bramon, Elvira E; Bumpstead, Suzannah J SJ; Casas, Juan P JP; Cork, Michael J MJ; Corvin, Aiden A; Deloukas, Panos P; Dilthey, Alexander A; Duncanson, Audrey A; Edkins, Sarah S; Estivill, Xavier X; Fitzgerald, Oliver O; Freeman, Colin C; Giardina, Emiliano E; Gray, Emma E; Hofer, Angelika A; Hüffmeier, Ulrike U; Hunt, Sarah E SE; Irvine, Alan D AD; Jankowski, Janusz J; Kirby, Brian B; Langford, Cordelia C; Lascorz, Jesús J; Leman, Joyce J; Leslie, Stephen S; Mallbris, Lotus L; Markus, Hugh S HS; Mathew, Christopher G CG; McLean, W H Irwin WH; McManus, Ross R; Mössner, Rotraut R; Moutsianas, Loukas L; Naluai, Asa T AT; Nestle, Frank O FO; Novelli, Giuseppe G; Onoufriadis, Alexandros A; Palmer, Colin N A CN; Perricone, Carlo C; Pirinen, Matti M; Plomin, Robert R; Potter, Simon C SC; Pujol, Ramon M RM; Rautanen, Anna A; Riveira-Munoz, Eva E; Ryan, Anthony W AW; Salmhofer, Wolfgang W; Samuelsson, Lena L; Sawcer, Stephen J SJ; Schalkwijk, Joost J; Smith, Catherine H CH; Ståhle, Mona M; Su, Zhan Z; Tazi-Ahnini, Rachid R; Traupe, Heiko H; Viswanathan, Ananth C AC; Warren, Richard B RB; Weger, Wolfgang W; Wolk, Katarina K; Wood, Nicholas N; Worthington, Jane J; Young, Helen S HS; Zeeuwen, Patrick L J M PL; Hayday, Adrian A; Burden, A David AD; Griffiths, Christopher E M CE; Kere, Juha J; Reis, André A; McVean, Gilean G; Evans, David M DM; Brown, Matthew A MA; Barker, Jonathan N JN; Peltonen, Leena L; Donnelly, Peter P; Trembath, Richard C RC
The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes.
Bmc Medical Genetics
Cooper, Jason D JD; Smyth, Deborah J DJ; Bailey, Rebecca R; Payne, Felicity F; Downes, Kate K; Godfrey, Lisa M LM; Masters, Jennifer J; Zeitels, Lauren R LR; Vella, Adrian A; Walker, Neil M NM; Todd, John A JA