SDHA c.1471G>T ;(p.E491*)

Variant ID: 5-240511-G-T

NM_004168.2(SDHA):c.1471G>T;(p.E491*)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Secondary resistance to anti-EGFR therapy by transcriptional reprogramming in patient-derived colorectal cancer models.

Genome Medicine
Vangala, Deepak D; Ladigan, Swetlana S; Liffers, Sven T ST; Noseir, Soha S; Maghnouj, Abdelouahid A; Götze, Tina-Maria TM; Verdoodt, Berlinda B; Klein-Scory, Susanne S; Godfrey, Laura L; Zowada, Martina K MK; Huerta, Mario M; Edelstein, Daniel L DL; de Villarreal, Jaime Martinez JM; Marqués, Miriam M; Kumbrink, Jörg J; Jung, Andreas A; Schiergens, Tobias T; Werner, Jens J; Heinemann, Volker V; Stintzing, Sebastian S; Lindoerfer, Doris D; Mansmann, Ulrich U; Pohl, Michael M; Teschendorf, Christian C; Bernhardt, Christiane C; Wolters, Heiner H; Stern, Josef J; Usta, Selami S; Viebahn, Richard R; Admard, Jacob J; Casadei, Nicolas N; Fröhling, Stefan S; Ball, Claudia R CR; Siveke, Jens T JT; Glimm, Hanno H; Tannapfel, Andrea A; Schmiegel, Wolff W; Hahn, Stephan A SA
Publication Date: 2021-07-16

Variant appearance in text: SDHA: 1471G>T; Glu491Ter; rs778207102
PubMed Link: 34271981
Variant Present in the following documents:
  • 13073_2021_926_MOESM4_ESM.xlsx, sheet 3
View BVdb publication page



The emerging role and targetability of the TCA cycle in cancer metabolism.

Protein & Cell
Anderson, Nicole M NM; Mucka, Patrick P; Kern, Joseph G JG; Feng, Hui H
Publication Date: 2018-02

Variant appearance in text: SDHA: 1471G>T
PubMed Link: 28748451
Variant Present in the following documents:
  • Main text
  • 13238_2017_Article_451.pdf
View BVdb publication page



15 YEARS OF PARAGANGLIOMA: Clinical manifestations of paraganglioma syndromes types 1-5.

Endocrine-Related Cancer
Benn, Diana E DE; Robinson, Bruce G BG; Clifton-Bligh, Roderick J RJ
Publication Date: 2015-08

Variant appearance in text: SDHA: E491*
PubMed Link: 26273102
Variant Present in the following documents:
  • ERC150268.pdf
View BVdb publication page



Succinate dehydrogenase deficient gastrointestinal stromal tumors (GISTs) - a review.

The International Journal Of Biochemistry & Cell Biology
Miettinen, Markku M; Lasota, Jerzy J
Publication Date: 2014-08

Variant appearance in text: SDHA: 1471G>T; E491*
PubMed Link: 24886695
Variant Present in the following documents:
  • Main text
View BVdb publication page



Overexpression of insulin-like growth factor 1 receptor and frequent mutational inactivation of SDHA in wild-type SDHB-negative gastrointestinal stromal tumors.

Genes, Chromosomes & Cancer
Belinsky, Martin G MG; Rink, Lori L; Flieder, Douglas B DB; Jahromi, Mona S MS; Schiffman, Joshua D JD; Godwin, Andrew K AK; von Mehren, Margaret M
Publication Date: 2013-02

Variant appearance in text: SDHA: 1471G>T; Glu491*
PubMed Link: 23109135
Variant Present in the following documents:
  • Main text
View BVdb publication page