Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.
Nature Communications
Dadaev, Tokhir T; Saunders, Edward J EJ; Newcombe, Paul J PJ; Anokian, Ezequiel E; Leongamornlert, Daniel A DA; Brook, Mark N MN; Cieza-Borrella, Clara C; Mijuskovic, Martina M; Wakerell, Sarah S; Olama, Ali Amin Al AAA; Schumacher, Fredrick R FR; Berndt, Sonja I SI; Benlloch, Sara S; Ahmed, Mahbubl M; Goh, Chee C; Sheng, Xin X; Zhang, Zhuo Z; Muir, Kenneth K; Govindasami, Koveela K; Lophatananon, Artitaya A; Stevens, Victoria L VL; Gapstur, Susan M SM; Carter, Brian D BD; Tangen, Catherine M CM; Goodman, Phyllis P; Thompson, Ian M IM; Batra, Jyotsna J; Chambers, Suzanne S; Moya, Leire L; Clements, Judith J; Horvath, Lisa L; Tilley, Wayne W; Risbridger, Gail G; Gronberg, Henrik H; Aly, Markus M; Nordström, Tobias T; Pharoah, Paul P; Pashayan, Nora N; Schleutker, Johanna J; Tammela, Teuvo L J TLJ; Sipeky, Csilla C; Auvinen, Anssi A; Albanes, Demetrius D; Weinstein, Stephanie S; Wolk, Alicja A; Hakansson, Niclas N; West, Catharine C; Dunning, Alison M AM; Burnet, Neil N; Mucci, Lorelei L; Giovannucci, Edward E; Andriole, Gerald G; Cussenot, Olivier O; Cancel-Tassin, Géraldine G; Koutros, Stella S; Freeman, Laura E Beane LEB; Sorensen, Karina Dalsgaard KD; Orntoft, Torben Falck TF; Borre, Michael M; Maehle, Lovise L; Grindedal, Eli Marie EM; Neal, David E DE; Donovan, Jenny L JL; Hamdy, Freddie C FC; Martin, Richard M RM; Travis, Ruth C RC; Key, Tim J TJ; Hamilton, Robert J RJ; Fleshner, Neil E NE; Finelli, Antonio A; Ingles, Sue Ann SA; Stern, Mariana C MC; Rosenstein, Barry B; Kerns, Sarah S; Ostrer, Harry H; Lu, Yong-Jie YJ; Zhang, Hong-Wei HW; Feng, Ninghan N; Mao, Xueying X; Guo, Xin X; Wang, Guomin G; Sun, Zan Z; Giles, Graham G GG; Southey, Melissa C MC; MacInnis, Robert J RJ; FitzGerald, Liesel M LM; Kibel, Adam S AS; Drake, Bettina F BF; Vega, Ana A; Gómez-Caamaño, Antonio A; Fachal, Laura L; Szulkin, Robert R; Eklund, Martin M; Kogevinas, Manolis M; Llorca, Javier J; Castaño-Vinyals, Gemma G; Penney, Kathryn L KL; Stampfer, Meir M; Park, Jong Y JY; Sellers, Thomas A TA; Lin, Hui-Yi HY; Stanford, Janet L JL; Cybulski, Cezary C; Wokolorczyk, Dominika D; Lubinski, Jan J; Ostrander, Elaine A EA; Geybels, Milan S MS; Nordestgaard, Børge G BG; Nielsen, Sune F SF; Weisher, Maren M; Bisbjerg, Rasmus R; Røder, Martin Andreas MA; Iversen, Peter P; Brenner, Hermann H; Cuk, Katarina K; Holleczek, Bernd B; Maier, Christiane C; Luedeke, Manuel M; Schnoeller, Thomas T; Kim, Jeri J; Logothetis, Christopher J CJ; John, Esther M EM; Teixeira, Manuel R MR; Paulo, Paula P; Cardoso, Marta M; Neuhausen, Susan L SL; Steele, Linda L; Ding, Yuan Chun YC; De Ruyck, Kim K; De Meerleer, Gert G; Ost, Piet P; Razack, Azad A; Lim, Jasmine J; Teo, Soo-Hwang SH; Lin, Daniel W DW; Newcomb, Lisa F LF; Lessel, Davor D; Gamulin, Marija M; Kulis, Tomislav T; Kaneva, Radka R; Usmani, Nawaid N; Slavov, Chavdar C; Mitev, Vanio V; Parliament, Matthew M; Singhal, Sandeep S; Claessens, Frank F; Joniau, Steven S; Van den Broeck, Thomas T; Larkin, Samantha S; Townsend, Paul A PA; Aukim-Hastie, Claire C; Gago-Dominguez, Manuela M; Castelao, Jose Esteban JE; Martinez, Maria Elena ME; Roobol, Monique J MJ; Jenster, Guido G; van Schaik, Ron H N RHN; Menegaux, Florence F; Truong, Thérèse T; Koudou, Yves Akoli YA; Xu, Jianfeng J; Khaw, Kay-Tee KT; Cannon-Albright, Lisa L; Pandha, Hardev H; Michael, Agnieszka A; Kierzek, Andrzej A; Thibodeau, Stephen N SN; McDonnell, Shannon K SK; Schaid, Daniel J DJ; Lindstrom, Sara S; Turman, Constance C; Ma, Jing J; Hunter, David J DJ; Riboli, Elio E; Siddiq, Afshan A; Canzian, Federico F; Kolonel, Laurence N LN; Le Marchand, Loic L; Hoover, Robert N RN; Machiela, Mitchell J MJ; Kraft, Peter P; , ; Freedman, Matthew M; Wiklund, Fredrik F; Chanock, Stephen S; Henderson, Brian E BE; Easton, Douglas F DF; Haiman, Christopher A CA; Eeles, Rosalind A RA; Conti, David V DV; Kote-Jarai, Zsofia Z
A Review of Prostate Cancer Genome-Wide Association Studies (GWAS).
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Benafif, Sarah S; Kote-Jarai, Zsofia Z; Eeles, Rosalind A RA; ,
Interactions Between Genome-Wide Significant Genetic Variants and Circulating Concentrations of 25-Hydroxyvitamin D in Relation to Prostate Cancer Risk in the National Cancer Institute BPC3.
American Journal Of Epidemiology
Dimitrakopoulou, Vasiliki I VI; Travis, Ruth C RC; Shui, Irene M IM; Mondul, Alison A; Albanes, Demetrius D; Virtamo, Jarmo J; Agudo, Antonio A; Boeing, Heiner H; Bueno-de-Mesquita, H Bas HB; Gunter, Marc J MJ; Johansson, Mattias M; Khaw, Kay-Tee KT; Overvad, Kim K; Palli, Domenico D; Trichopoulou, Antonia A; Giovannucci, Edward E; Hunter, David J DJ; Lindström, Sara S; Willett, Walter W; Gaziano, J Michael JM; Stampfer, Meir M; Berg, Christine C; Berndt, Sonja I SI; Black, Amanda A; Hoover, Robert N RN; Kraft, Peter P; Key, Timothy J TJ; Tsilidis, Konstantinos K KK
Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity.
British Journal Of Cancer
Ahmed, Mahbubl M; Dorling, Leila L; Kerns, Sarah S; Fachal, Laura L; Elliott, Rebecca R; Partliament, Matt M; Rosenstein, Barry S BS; Vega, Ana A; Gómez-Caamaño, Antonio A; Barnett, Gill G; Dearnaley, David P DP; Hall, Emma E; Sydes, Matt M; Burnet, Neil N; Pharoah, Paul D P PD; Eeles, Ros R; West, Catharine M L CM
Identification of candidate genes for prostate cancer-risk SNPs utilizing a normal prostate tissue eQTL data set.
Nature Communications
Thibodeau, S N SN; French, A J AJ; McDonnell, S K SK; Cheville, J J; Middha, S S; Tillmans, L L; Riska, S S; Baheti, S S; Larson, M C MC; Fogarty, Z Z; Zhang, Y Y; Larson, N N; Nair, A A; O'Brien, D D; Wang, L L; Schaid, D J DJ
An analysis of the association between prostate cancer risk loci, PSA levels, disease aggressiveness and disease-specific mortality.
British Journal Of Cancer
Sullivan, J J; Kopp, R R; Stratton, K K; Manschreck, C C; Corines, M M; Rau-Murthy, R R; Hayes, J J; Lincon, A A; Ashraf, A A; Thomas, T T; Schrader, K K; Gallagher, D D; Hamilton, R R; Scher, H H; Lilja, H H; Scardino, P P; Eastham, J J; Offit, K K; Vijai, J J; Klein, R J RJ
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans.
Human Molecular Genetics
Amin Al Olama, Ali A; Dadaev, Tokhir T; Hazelett, Dennis J DJ; Li, Qiuyan Q; Leongamornlert, Daniel D; Saunders, Edward J EJ; Stephens, Sarah S; Cieza-Borrella, Clara C; Whitmore, Ian I; Benlloch Garcia, Sara S; Giles, Graham G GG; Southey, Melissa C MC; Fitzgerald, Liesel L; Gronberg, Henrik H; Wiklund, Fredrik F; Aly, Markus M; Henderson, Brian E BE; Schumacher, Fredrick F; Haiman, Christopher A CA; Schleutker, Johanna J; Wahlfors, Tiina T; Tammela, Teuvo L TL; Nordestgaard, Børge G BG; Key, Tim J TJ; Travis, Ruth C RC; Neal, David E DE; Donovan, Jenny L JL; Hamdy, Freddie C FC; Pharoah, Paul P; Pashayan, Nora N; Khaw, Kay-Tee KT; Stanford, Janet L JL; Thibodeau, Stephen N SN; Mcdonnell, Shannon K SK; Schaid, Daniel J DJ; Maier, Christiane C; Vogel, Walther W; Luedeke, Manuel M; Herkommer, Kathleen K; Kibel, Adam S AS; Cybulski, Cezary C; Wokołorczyk, Dominika D; Kluzniak, Wojciech W; Cannon-Albright, Lisa L; Brenner, Hermann H; Butterbach, Katja K; Arndt, Volker V; Park, Jong Y JY; Sellers, Thomas T; Lin, Hui-Yi HY; Slavov, Chavdar C; Kaneva, Radka R; Mitev, Vanio V; Batra, Jyotsna J; Clements, Judith A JA; Spurdle, Amanda A; Teixeira, Manuel R MR; Paulo, Paula P; Maia, Sofia S; Pandha, Hardev H; Michael, Agnieszka A; Kierzek, Andrzej A; Govindasami, Koveela K; Guy, Michelle M; Lophatonanon, Artitaya A; Muir, Kenneth K; Viñuela, Ana A; Brown, Andrew A AA; , ; , ; , ; , ; , ; Freedman, Mathew M; Conti, David V DV; Easton, Douglas D; Coetzee, Gerhard A GA; Eeles, Rosalind A RA; Kote-Jarai, Zsofia Z
Genome-wide association scan for variants associated with early-onset prostate cancer.
Plos One
Lange, Ethan M EM; Johnson, Anna M AM; Wang, Yunfei Y; Zuhlke, Kimberly A KA; Lu, Yurong Y; Ribado, Jessica V JV; Keele, Gregory R GR; Li, Jin J; Duan, Qing Q; Li, Ge G; Gao, Zhengrong Z; Li, Yun Y; Xu, Jianfeng J; Isaacs, William B WB; Zheng, Siqun S; Cooney, Kathleen A KA
Comprehensive functional annotation of 77 prostate cancer risk loci.
Plos Genetics
Hazelett, Dennis J DJ; Rhie, Suhn Kyong SK; Gaddis, Malaina M; Yan, Chunli C; Lakeland, Daniel L DL; Coetzee, Simon G SG; , ; , ; Henderson, Brian E BE; Noushmehr, Houtan H; Cozen, Wendy W; Kote-Jarai, Zsofia Z; Eeles, Rosalind A RA; Easton, Douglas F DF; Haiman, Christopher A CA; Lu, Wange W; Farnham, Peggy J PJ; Coetzee, Gerhard A GA
A genome-wide association study of prostate cancer in West African men.
Human Genetics
Cook, Michael Blaise MB; Wang, Zhaoming Z; Yeboah, Edward D ED; Tettey, Yao Y; Biritwum, Richard B RB; Adjei, Andrew A AA; Tay, Evelyn E; Truelove, Ann A; Niwa, Shelley S; Chung, Charles C CC; Chokkalingam, Annand P AP; Chu, Lisa W LW; Yeager, Meredith M; Hutchinson, Amy A; Yu, Kai K; Rand, Kristin A KA; Haiman, Christopher A CA; , ; Hoover, Robert N RN; Hsing, Ann W AW; Chanock, Stephen J SJ
Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.
Plos Genetics
Haiman, Christopher A CA; Han, Ying Y; Feng, Ye Y; Xia, Lucy L; Hsu, Chris C; Sheng, Xin X; Pooler, Loreall C LC; Patel, Yesha Y; Kolonel, Laurence N LN; Carter, Erin E; Park, Karen K; Le Marchand, Loic L; Van Den Berg, David D; Henderson, Brian E BE; Stram, Daniel O DO
Clinical implications of family history of prostate cancer and genetic risk single nucleotide polymorphism (SNP) profiles in an active surveillance cohort.
Bju International
Goh, Chee L CL; Saunders, Edward J EJ; Leongamornlert, Daniel A DA; Tymrakiewicz, Malgorzata M; Thomas, Karen K; Selvadurai, Elizabeth D ED; Woode-Amissah, Ruth R; Dadaev, Tokhir T; Mahmud, Nadiya N; Castro, Elena E; Olmos, David D; Guy, Michelle M; Govindasami, Koveela K; O'Brien, Lynne T LT; Hall, Amanda L AL; Wilkinson, Rosemary A RA; Sawyer, Emma J EJ; Al Olama, Ali Amin AA; Easton, Douglas F DF; Kote-Jarai, Zsofia Z; Parker, Chris C CC; Eeles, Rosalind A RA
Common genetic variants associated with disease from genome-wide association studies are mutually exclusive in prostate cancer and rheumatoid arthritis.
Bju International
Orozco, Gisela G; Goh, Chee L CL; Al Olama, Ali Amin AA; Benlloch-Garcia, Sara S; Govindasami, Koveela K; Guy, Michelle M; Muir, Kenneth R KR; Giles, Graham G GG; Severi, Gianluca G; Neal, David E DE; Hamdy, Freddie C FC; Donovan, Jenny L JL; Kote-Jarai, Zsofia Z; Easton, Douglas F DF; Eyre, Steve S; Eeles, Rosalind A RA
Evaluating genetic risk for prostate cancer among Japanese and Latinos.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Cheng, Iona I; Chen, Gary K GK; Nakagawa, Hidewaki H; He, Jing J; Wan, Peggy P; Laurie, Cathy C CC; Shen, Jess J; Sheng, Xin X; Pooler, Loreall C LC; Crenshaw, Andrew T AT; Mirel, Daniel B DB; Takahashi, Atsushi A; Kubo, Michiaki M; Nakamura, Yusuke Y; Al Olama, Ali Amin AA; Benlloch, Sara S; Donovan, Jenny L JL; Guy, Michelle M; Hamdy, Freddie C FC; Kote-Jarai, Zsofia Z; Neal, David E DE; Wilkens, Lynne R LR; Monroe, Kristine R KR; Stram, Daniel O DO; Muir, Kenneth K; Eeles, Rosalind A RA; Easton, Douglas F DF; Kolonel, Laurence N LN; Henderson, Brian E BE; Le Marchand, Loïc L; Haiman, Christopher A CA