Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits.
Nature Communications
Liu, Lili L; Khan, Atlas A; Sanchez-Rodriguez, Elena E; Zanoni, Francesca F; Li, Yifu Y; Steers, Nicholas N; Balderes, Olivia O; Zhang, Junying J; Krithivasan, Priya P; LeDesma, Robert A RA; Fischman, Clara C; Hebbring, Scott J SJ; Harley, John B JB; Moncrieffe, Halima H; Kottyan, Leah C LC; Namjou-Khales, Bahram B; Walunas, Theresa L TL; Knevel, Rachel R; Raychaudhuri, Soumya S; Karlson, Elizabeth W EW; Denny, Joshua C JC; Stanaway, Ian B IB; Crosslin, David D; Rauen, Thomas T; Floege, Jürgen J; Eitner, Frank F; Moldoveanu, Zina Z; Reily, Colin C; Knoppova, Barbora B; Hall, Stacy S; Sheff, Justin T JT; Julian, Bruce A BA; Wyatt, Robert J RJ; Suzuki, Hitoshi H; Xie, Jingyuan J; Chen, Nan N; Zhou, Xujie X; Zhang, Hong H; Hammarström, Lennart L; Viktorin, Alexander A; Magnusson, Patrik K E PKE; Shang, Ning N; Hripcsak, George G; Weng, Chunhua C; Rundek, Tatjana T; Elkind, Mitchell S V MSV; Oelsner, Elizabeth C EC; Barr, R Graham RG; Ionita-Laza, Iuliana I; Novak, Jan J; Gharavi, Ali G AG; Kiryluk, Krzysztof K
Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.
Nature Genetics
Robertson, Catherine C CC; Inshaw, Jamie R J JRJ; Onengut-Gumuscu, Suna S; Chen, Wei-Min WM; Santa Cruz, David Flores DF; Yang, Hanzhi H; Cutler, Antony J AJ; Crouch, Daniel J M DJM; Farber, Emily E; Bridges, S Louis SL; Edberg, Jeffrey C JC; Kimberly, Robert P RP; Buckner, Jane H JH; Deloukas, Panos P; Divers, Jasmin J; Dabelea, Dana D; Lawrence, Jean M JM; Marcovina, Santica S; Shah, Amy S AS; Greenbaum, Carla J CJ; Atkinson, Mark A MA; Gregersen, Peter K PK; Oksenberg, Jorge R JR; Pociot, Flemming F; Rewers, Marian J MJ; Steck, Andrea K AK; Dunger, David B DB; , ; Wicker, Linda S LS; Concannon, Patrick P; Todd, John A JA; Rich, Stephen S SS
Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.
Nature Genetics
Robertson, Catherine C CC; Inshaw, Jamie R J JRJ; Onengut-Gumuscu, Suna S; Chen, Wei-Min WM; Santa Cruz, David Flores DF; Yang, Hanzhi H; Cutler, Antony J AJ; Crouch, Daniel J M DJM; Farber, Emily E; Bridges, S Louis SL; Edberg, Jeffrey C JC; Kimberly, Robert P RP; Buckner, Jane H JH; Deloukas, Panos P; Divers, Jasmin J; Dabelea, Dana D; Lawrence, Jean M JM; Marcovina, Santica S; Shah, Amy S AS; Greenbaum, Carla J CJ; Atkinson, Mark A MA; Gregersen, Peter K PK; Oksenberg, Jorge R JR; Pociot, Flemming F; Rewers, Marian J MJ; Steck, Andrea K AK; Dunger, David B DB; , ; Wicker, Linda S LS; Concannon, Patrick P; Todd, John A JA; Rich, Stephen S SS
Lymphocyte DNA methylation mediates genetic risk at shared immune-mediated disease loci.
The Journal Of Allergy And Clinical Immunology
Clark, Alexander D AD; Nair, Nisha N; Anderson, Amy E AE; Thalayasingam, Nishanthi N; Naamane, Najib N; Skelton, Andrew J AJ; Diboll, Julie J; Barton, Anne A; Eyre, Stephen S; Isaacs, John D JD; Pratt, Arthur G AG; Reynard, Louise N LN
Fine-mapping inflammatory bowel disease loci to single-variant resolution.
Nature
Huang, Hailiang H; Fang, Ming M; Jostins, Luke L; Umićević Mirkov, Maša M; Boucher, Gabrielle G; Anderson, Carl A CA; Andersen, Vibeke V; Cleynen, Isabelle I; Cortes, Adrian A; Crins, François F; D'Amato, Mauro M; Deffontaine, Valérie V; Dmitrieva, Julia J; Docampo, Elisa E; Elansary, Mahmoud M; Farh, Kyle Kai-How KK; Franke, Andre A; Gori, Ann-Stephan AS; Goyette, Philippe P; Halfvarson, Jonas J; Haritunians, Talin T; Knight, Jo J; Lawrance, Ian C IC; Lees, Charlie W CW; Louis, Edouard E; Mariman, Rob R; Meuwissen, Theo T; Mni, Myriam M; Momozawa, Yukihide Y; Parkes, Miles M; Spain, Sarah L SL; Théâtre, Emilie E; Trynka, Gosia G; Satsangi, Jack J; van Sommeren, Suzanne S; Vermeire, Severine S; Xavier, Ramnik J RJ; , ; Weersma, Rinse K RK; Duerr, Richard H RH; Mathew, Christopher G CG; Rioux, John D JD; McGovern, Dermot P B DPB; Cho, Judy H JH; Georges, Michel M; Daly, Mark J MJ; Barrett, Jeffrey C JC
Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation.
Science Advances
Andlauer, Till F M TF; Buck, Dorothea D; Antony, Gisela G; Bayas, Antonios A; Bechmann, Lukas L; Berthele, Achim A; Chan, Andrew A; Gasperi, Christiane C; Gold, Ralf R; Graetz, Christiane C; Haas, Jürgen J; Hecker, Michael M; Infante-Duarte, Carmen C; Knop, Matthias M; Kümpfel, Tania T; Limmroth, Volker V; Linker, Ralf A RA; Loleit, Verena V; Luessi, Felix F; Meuth, Sven G SG; Mühlau, Mark M; Nischwitz, Sandra S; Paul, Friedemann F; Pütz, Michael M; Ruck, Tobias T; Salmen, Anke A; Stangel, Martin M; Stellmann, Jan-Patrick JP; Stürner, Klarissa H KH; Tackenberg, Björn B; Then Bergh, Florian F; Tumani, Hayrettin H; Warnke, Clemens C; Weber, Frank F; Wiendl, Heinz H; Wildemann, Brigitte B; Zettl, Uwe K UK; Ziemann, Ulf U; Zipp, Frauke F; Arloth, Janine J; Weber, Peter P; Radivojkov-Blagojevic, Milena M; Scheinhardt, Markus O MO; Dankowski, Theresa T; Bettecken, Thomas T; Lichtner, Peter P; Czamara, Darina D; Carrillo-Roa, Tania T; Binder, Elisabeth B EB; Berger, Klaus K; Bertram, Lars L; Franke, Andre A; Gieger, Christian C; Herms, Stefan S; Homuth, Georg G; Ising, Marcus M; Jöckel, Karl-Heinz KH; Kacprowski, Tim T; Kloiber, Stefan S; Laudes, Matthias M; Lieb, Wolfgang W; Lill, Christina M CM; Lucae, Susanne S; Meitinger, Thomas T; Moebus, Susanne S; Müller-Nurasyid, Martina M; Nöthen, Markus M MM; Petersmann, Astrid A; Rawal, Rajesh R; Schminke, Ulf U; Strauch, Konstantin K; Völzke, Henry H; Waldenberger, Melanie M; Wellmann, Jürgen J; Porcu, Eleonora E; Mulas, Antonella A; Pitzalis, Maristella M; Sidore, Carlo C; Zara, Ilenia I; Cucca, Francesco F; Zoledziewska, Magdalena M; Ziegler, Andreas A; Hemmer, Bernhard B; Müller-Myhsok, Bertram B
Identification of rheumatoid arthritis biomarkers based on single nucleotide polymorphisms and haplotype blocks: A systematic review and meta-analysis.
Journal Of Advanced Research
Saad, Mohamed N MN; Mabrouk, Mai S MS; Eldeib, Ayman M AM; Shaker, Olfat G OG
Genotyping of immune-related genetic variants identifies TYK2 as a novel associated locus for idiopathic inflammatory myopathies.
Annals Of The Rheumatic Diseases
Jani, M M; Massey, J J; Wedderburn, L R LR; Vencovský, J J; Danko, K K; Lundberg, I E IE; Padyukov, L L; Selva-O'Callaghan, A A; Radstake, T T; Platt, H H; Warren, R B RB; Griffiths, C E CE; Lee, A A; Gregersen, P K PK; Miller, F W FW; Ollier, W E WE; Cooper, R G RG; Chinoy, H H; Lamb, J A JA; ,
Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.
Arthritis & Rheumatology (Hoboken, N.J.)
Orozco, Gisela G; Viatte, Sebastien S; Bowes, John J; Martin, Paul P; Wilson, Anthony G AG; Morgan, Ann W AW; Steer, Sophia S; Wordsworth, Paul P; Hocking, Lynne J LJ; , ; , ; , ; Barton, Anne A; Worthington, Jane J; Eyre, Stephen S
Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.
Plos Genetics
Scott, Ian C IC; Seegobin, Seth D SD; Steer, Sophia S; Tan, Rachael R; Forabosco, Paola P; Hinks, Anne A; Eyre, Stephen S; Morgan, Ann W AW; Wilson, Anthony G AG; Hocking, Lynne J LJ; Wordsworth, Paul P; Barton, Anne A; Worthington, Jane J; Cope, Andrew P AP; Lewis, Cathryn M CM
Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans.
Plos One
Cobb, Joanna E JE; Plant, Darren D; Flynn, Edward E; Tadjeddine, Meriem M; Dieudé, Philippe P; Cornélis, François F; Ärlestig, Lisbeth L; Dahlqvist, Solbritt Rantapää SR; Goulielmos, George G; Boumpas, Dimitrios T DT; Sidiropoulos, Prodromos P; Krintel, Sophine B SB; Ørnbjerg, Lykke M LM; Hetland, Merete L ML; Klareskog, Lars L; Haeupl, Thomas T; Filer, Andrew A; Buckley, Christopher D CD; Raza, Karim K; Witte, Torsten T; Schmidt, Reinhold E RE; FitzGerald, Oliver O; Veale, Douglas D; Eyre, Stephen S; Worthington, Jane J
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Plos Genetics
Lauc, Gordan G; Huffman, Jennifer E JE; Pučić, Maja M; Zgaga, Lina L; Adamczyk, Barbara B; Mužinić, Ana A; Novokmet, Mislav M; Polašek, Ozren O; Gornik, Olga O; Krištić, Jasminka J; Keser, Toma T; Vitart, Veronique V; Scheijen, Blanca B; Uh, Hae-Won HW; Molokhia, Mariam M; Patrick, Alan Leslie AL; McKeigue, Paul P; Kolčić, Ivana I; Lukić, Ivan Krešimir IK; Swann, Olivia O; van Leeuwen, Frank N FN; Ruhaak, L Renee LR; Houwing-Duistermaat, Jeanine J JJ; Slagboom, P Eline PE; Beekman, Marian M; de Craen, Anton J M AJ; Deelder, André M AM; Zeng, Qiang Q; Wang, Wei W; Hastie, Nicholas D ND; Gyllensten, Ulf U; Wilson, James F JF; Wuhrer, Manfred M; Wright, Alan F AF; Rudd, Pauline M PM; Hayward, Caroline C; Aulchenko, Yurii Y; Campbell, Harry H; Rudan, Igor I
Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap.
Annals Of The Rheumatic Diseases
Hinks, Anne A; Cobb, Joanna J; Sudman, Marc M; Eyre, Stephen S; Martin, Paul P; Flynn, Edward E; Packham, Jonathon J; , ; , ; , ; Barton, Anne A; Worthington, Jane J; Langefeld, Carl D CD; Glass, David N DN; Thompson, Susan D SD; Thomson, Wendy W
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
Nature Genetics
Stahl, Eli A EA; Raychaudhuri, Soumya S; Remmers, Elaine F EF; Xie, Gang G; Eyre, Stephen S; Thomson, Brian P BP; Li, Yonghong Y; Kurreeman, Fina A S FA; Zhernakova, Alexandra A; Hinks, Anne A; Guiducci, Candace C; Chen, Robert R; Alfredsson, Lars L; Amos, Christopher I CI; Ardlie, Kristin G KG; , ; Barton, Anne A; Bowes, John J; Brouwer, Elisabeth E; Burtt, Noel P NP; Catanese, Joseph J JJ; Coblyn, Jonathan J; Coenen, Marieke J H MJ; Costenbader, Karen H KH; Criswell, Lindsey A LA; Crusius, J Bart A JB; Cui, Jing J; de Bakker, Paul I W PI; De Jager, Philip L PL; Ding, Bo B; Emery, Paul P; Flynn, Edward E; Harrison, Pille P; Hocking, Lynne J LJ; Huizinga, Tom W J TW; Kastner, Daniel L DL; Ke, Xiayi X; Lee, Annette T AT; Liu, Xiangdong X; Martin, Paul P; Morgan, Ann W AW; Padyukov, Leonid L; Posthumus, Marcel D MD; Radstake, Timothy R D J TR; Reid, David M DM; Seielstad, Mark M; Seldin, Michael F MF; Shadick, Nancy A NA; Steer, Sophia S; Tak, Paul P PP; Thomson, Wendy W; van der Helm-van Mil, Annette H M AH; van der Horst-Bruinsma, Irene E IE; van der Schoot, C Ellen CE; van Riel, Piet L C M PL; Weinblatt, Michael E ME; Wilson, Anthony G AG; Wolbink, Gert Jan GJ; Wordsworth, B Paul BP; , ; Wijmenga, Cisca C; Karlson, Elizabeth W EW; Toes, Rene E M RE; de Vries, Niek N; Begovich, Ann B AB; Worthington, Jane J; Siminovitch, Katherine A KA; Gregersen, Peter K PK; Klareskog, Lars L; Plenge, Robert M RM