Publications:

Statin shapes inflamed tumor microenvironment and enhances immune checkpoint blockade in non-small cell lung cancer.

Jci Insight

Mao, Wenjun W; Cai, Yun Y; Chen, Danrong D; Jiang, Guanyu G; Xu, Yongrui Y; Chen, Ruo R; Wang, Fengxu F; Wang, Xuehai X; Zheng, Mingfeng M; Zhao, Xinyuan X; Mei, Jie J

Publication Date: 2022-09-22

Variant appearance in text: HMGCR: F12K

PubMed Link: 35943796

Variant Present in the following documents:

• jciinsight-7-161940.pdf

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SOAT1 Promotes Gastric Cancer Lymph Node Metastasis Through Lipid Synthesis.

Frontiers In Pharmacology

Zhu, Tingting T; Wang, Zhangding Z; Zou, Tianhui T; Xu, Lei L; Zhang, Shu S; Chen, Yali Y; Chen, Chen C; Zhang, Weijie W; Wang, Shouyu S; Ding, Qingqing Q; Xu, Guifang G

Publication Date: 2021

Variant appearance in text: HMGCR: F12K

PubMed Link: 34790132

Variant Present in the following documents:

• Main text
• fphar-12-769647.pdf

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Dysregulated cholesterol homeostasis results in resistance to ferroptosis increasing tumorigenicity and metastasis in cancer.

Nature Communications

Liu, Wen W; Chakraborty, Binita B; Safi, Rachid R; Kazmin, Dmitri D; Chang, Ching-Yi CY; McDonnell, Donald P DP

Publication Date: 2021-08-24

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PubMed Link: 34429409

Variant Present in the following documents:

• Main text
• 41467_2021_Article_25354.pdf

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The epigenetic drug 5-azacytidine interferes with cholesterol and lipid metabolism.

The Journal Of Biological Chemistry

Poirier, Steve S; Samami, Samaneh S; Mamarbachi, Maya M; Demers, Annie A; Chang, Ta Yuan TY; Vance, Dennis E DE; Hatch, Grant M GM; Mayer, Gaétan G

Publication Date: 2014-07-04

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PubMed Link: 24855646

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• Main text

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Identification of a benzamide derivative that inhibits stress-induced adrenal corticosteroid synthesis.

Molecules (Basel, Switzerland)

Xu, Jing J; Lecanu, Laurent L; Tan, Matthew M; Greeson, Janet J; Papadopoulos, Vassilios V

Publication Date: 2009-09-03

Variant appearance in text: HMGCR: F12K

PubMed Link: 19783933

Variant Present in the following documents:

• Main text
• molecules-14-03392.pdf

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