HMGCR c.150T>C ;(p.C50=)

Variant ID: 5-74638580-T-C

NM_000859.2(HMGCR):c.150T>C;(p.C50=)

This variant was identified in 5 publications

View GRCh38 version.



Variant-Specific Resource Links:
gnomAD v2.1.1
Mutalizer Name Checker
Google
UCSC Genome Browser
ClinVar
dbSNP

Publications:

The metabolic and molecular mechanisms of α‑mangostin in cardiometabolic disorders (Review).

International Journal Of Molecular Medicine
John, Oliver Dean OD; Mushunje, Annals Tatenda AT; Surugau, Noumie N; Guad, Rhanye Mac RM
Publication Date: 2022-09

Variant appearance in text: HMGCR: C50=
PubMed Link: 35904170
Variant Present in the following documents:
  • ijmm-50-3-05176.pdf
View BVdb publication page


KLF5 inhibition overcomes oxaliplatin resistance in patient-derived colorectal cancer organoids by restoring apoptotic response.

Cell Death & Disease
Shen, Xiaohui X; Zhang, Yuchen Y; Xu, Zhuoqing Z; Gao, Han H; Feng, Wenqing W; Li, Wenchang W; Miao, Yiming Y; Xu, Zifeng Z; Zong, Yaping Y; Zhao, Jingkun J; Lu, Aiguo A
Publication Date: 2022-04-05

Variant appearance in text: HMGCR: C50=
PubMed Link: 35379798
Variant Present in the following documents:
  • 41419_2022_4773_MOESM9_ESM.xlsx, sheet 1
View BVdb publication page


An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

Cell Chemical Biology
Zhang, Yuehui Y; Shang, Limin L; Zhang, Jing J; Liu, Yuchen Y; Jin, Chaozhi C; Zhao, Yanan Y; Lei, Xiaobo X; Wang, Wenjing W; Xiao, Xia X; Zhang, Xiuyuan X; Liu, Yujiao Y; Liu, Linlin L; Zhuang, Meng-Wei MW; Mi, Qingkun Q; Tian, Chunyan C; Wang, Jianwei J; He, Fuchu F; Wang, Pei-Hui PH; Wang, Jian J
Publication Date: 2021-10-19

Variant appearance in text: HMGCR: C50=
PubMed Link: 34672954
Variant Present in the following documents:
  • main.pdf
  • mmc7.pdf
View BVdb publication page


An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

Cell Chemical Biology
Zhang, Yuehui Y; Shang, Limin L; Zhang, Jing J; Liu, Yuchen Y; Jin, Chaozhi C; Zhao, Yanan Y; Lei, Xiaobo X; Wang, Wenjing W; Xiao, Xia X; Zhang, Xiuyuan X; Liu, Yujiao Y; Liu, Linlin L; Zhuang, Meng-Wei MW; Mi, Qingkun Q; Tian, Chunyan C; Wang, Jianwei J; He, Fuchu F; Wang, Pei-Hui PH; Wang, Jian J
Publication Date: 2022-01-20

Variant appearance in text: HMGCR: C50=
PubMed Link: 34672954
Variant Present in the following documents:
  • main.pdf
  • mmc7.pdf
View BVdb publication page


Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export.

Nature Communications
Heybrock, Saskia S; Kanerva, Kristiina K; Meng, Ying Y; Ing, Chris C; Liang, Anna A; Xiong, Zi-Jian ZJ; Weng, Xialian X; Ah Kim, Young Y; Collins, Richard R; Trimble, William W; Pomès, Régis R; Privé, Gilbert G GG; Annaert, Wim W; Schwake, Michael M; Heeren, Joerg J; Lüllmann-Rauch, Renate R; Grinstein, Sergio S; Ikonen, Elina E; Saftig, Paul P; Neculai, Dante D
Publication Date: 2019-08-06

Variant appearance in text: HMGCR: C50=
PubMed Link: 31387993
Variant Present in the following documents:
  • 41467_2019_11425_MOESM1_ESM.pdf
View BVdb publication page


The fatty acid synthase inhibitor triclosan: repurposing an anti-microbial agent for targeting prostate cancer.

Oncotarget
Sadowski, Martin C MC; Pouwer, Rebecca H RH; Gunter, Jennifer H JH; Lubik, Amy A AA; Quinn, Ronald J RJ; Nelson, Colleen C CC
Publication Date: 2014-10-15

Variant appearance in text: HMGCR: C50=
PubMed Link: 25313139
Variant Present in the following documents:
  • Main text
  • oncotarget-05-9362.pdf
View BVdb publication page