Publications:

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GENetic characteristics and REsponse to lipid-lowering therapy in familial hypercholesterolemia: GENRE-FH study.

Scientific Reports

H Kim, CJ Lee, H Pak, DI Kim, MY Rhee, BK Lee, Y Ahn, BR Cho, JT Woo, SH Hur, JO Jeong, JH Lee, SH Lee

Publication Date: 2020-11-09

Variant appearance in text: rs12654264

PubMed Link: 33168860

Variant Present in the following documents:

• Main text

View BVdb publication page

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Model of genetic and environmental factors associated with type 2 diabetes mellitus in a Chinese Han population.

Bmc Public Health

Z Li, CY Ye, TY Zhao, L Yang

Publication Date: 2020-06-29

Variant appearance in text: rs12654264

PubMed Link: 32600448

Variant Present in the following documents:

• Main text

View BVdb publication page

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Relationship between ethanol consumption and TBL2 rs17145738 on LDL-C concentration in Japanese adults: a four season 3-day weighed diet record study.

Bmc Nutrition

S Akimoto, C Goto, K Kuriki

Publication Date: 2019

Variant appearance in text: rs12654264

PubMed Link: 32153974

Variant Present in the following documents:

• Main text

View BVdb publication page

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Progressive effects of single-nucleotide polymorphisms on 16 phenotypic traits based on longitudinal data.

Genes & Genomics

D Li, H Kang, S Lee, S Won

Publication Date: 2020-04

Variant appearance in text: rs12654264

PubMed Link: 31902109

Variant Present in the following documents:

• Main text

View BVdb publication page

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Lipid lowering and Alzheimer disease risk: A mendelian randomization study.

Annals Of Neurology

DM Williams, C Finan, AF Schmidt, S Burgess, AD Hingorani

Publication Date: 2020-01

Variant appearance in text: rs12654264

PubMed Link: 31714636

Variant Present in the following documents:

• ANA-87-30-s001.docx

View BVdb publication page

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Genetic architecture of human plasma lipidome and its link to cardiovascular disease.

Nature Communications

R Tabassum, JT Rämö, P Ripatti, JT Koskela, M Kurki, J Karjalainen, P Palta, S Hassan, J Nunez-Fontarnau, TTJ Kiiskinen, S Söderlund, N Matikainen, MJ Gerl, MA Surma, C Klose, NO Stitziel, H Laivuori, AS Havulinna, SK Service, V Salomaa, M Pirinen, , M Jauhiainen, MJ Daly, NB Freimer, A Palotie, MR Taskinen, K Simons, S Ripatti

Publication Date: 2019-09-24

Variant appearance in text: rs12654264

PubMed Link: 31551469

Variant Present in the following documents:

• 41467_2019_11954_MOESM13_ESM.xlsx
• 41467_2019_11954_MOESM14_ESM.xlsx

View BVdb publication page

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The transferability of lipid loci across African, Asian and European cohorts.

Nature Communications

K Kuchenbaecker, N Telkar, T Reiker, RG Walters, K Lin, A Eriksson, D Gurdasani, A Gilly, L Southam, E Tsafantakis, M Karaleftheri, J Seeley, A Kamali, G Asiki, IY Millwood, M Holmes, H Du, Y Guo, M Kumari, G Dedoussis, L Li, Z Chen, MS Sandhu, E Zeggini,

Publication Date: 2019-09-24

Variant appearance in text: rs12654264

PubMed Link: 31551420

Variant Present in the following documents:

• 41467_2019_12026_MOESM1_ESM.pdf
• 41467_2019_12026_MOESM2_ESM.pdf

View BVdb publication page

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The Association of Polymorphisms in Circadian Clock and Lipid Metabolism Genes With 2nd Trimester Lipid Levels and Preterm Birth.

Frontiers In Genetics

U Kovac, EA Jasper, CJ Smith, RJ Baer, B Bedell, BM Donovan, N Weathers, U Prosenc Zmrzljak, LL Jelliffe-Pawlowski, D Rozman, KK Ryckman

Publication Date: 2019

Variant appearance in text: rs12654264

PubMed Link: 31249592

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic markers of lipid metabolism genes associated with low susceptibility to HCV infection.

Scientific Reports

LM Real, J Macías, A Rivero-Juárez, F Téllez, D Merino, S Moreno-Grau, A Orellana, J Gómez-Salgado, ME Sáez, M Frías, A Corma-Gómez, N Merchante, A Ruiz, A Caruz, JA Pineda,

Publication Date: 2019-06-21

Variant appearance in text: rs12654264

PubMed Link: 31227787

Variant Present in the following documents:

• Main text

View BVdb publication page

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Discovery of Allele-Specific Protein-RNA Interactions in Human Transcriptomes.

American Journal Of Human Genetics

E Bahrami-Samani, Y Xing

Publication Date: 2019-03-07

Variant appearance in text: rs12654264

PubMed Link: 30827501

Variant Present in the following documents:

• mmc6.xlsx
• mmc7.xlsx

View BVdb publication page

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Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.

Nature Communications

TO Kilpeläinen, AR Bentley, R Noordam, YJ Sung, K Schwander, TW Winkler, H Jakupović, DI Chasman, A Manning, I Ntalla, H Aschard, MR Brown, L de Las Fuentes, N Franceschini, X Guo, D Vojinovic, S Aslibekyan, MF Feitosa, M Kho, SK Musani, M Richard, H Wang, Z Wang, TM Bartz, LF Bielak, A Campbell, R Dorajoo, V Fisher, FP Hartwig, ARVR Horimoto, C Li, KK Lohman, J Marten, X Sim, AV Smith, SM Tajuddin, M Alver, M Amini, M Boissel, JF Chai, X Chen, J Divers, E Evangelou, C Gao, M Graff, SE Harris, M He, FC Hsu, AU Jackson, JH Zhao, AT Kraja, B Kühnel, F Laguzzi, LP Lyytikäinen, IM Nolte, R Rauramaa, M Riaz, A Robino, R Rueedi, HM Stringham, F Takeuchi, PJ van der Most, TV Varga, N Verweij, EB Ware, W Wen, X Li, LR Yanek, N Amin, DK Arnett, E Boerwinkle, M Brumat, B Cade, M Canouil, YI Chen, MP Concas, J Connell, R de Mutsert, HJ de Silva, PS de Vries, A Demirkan, J Ding, CB Eaton, JD Faul, Y Friedlander, KP Gabriel, M Ghanbari, F Giulianini, CC Gu, D Gu, TB Harris, J He, S Heikkinen, CK Heng, SC Hunt, MA Ikram, JB Jonas, WP Koh, P Komulainen, JE Krieger, SB Kritchevsky, Z Kutalik, J Kuusisto, CD Langefeld, C Langenberg, LJ Launer, K Leander, RN Lemaitre, CE Lewis, J Liang, , J Liu, R Mägi, A Manichaikul, T Meitinger, A Metspalu, Y Milaneschi, KL Mohlke, TH Mosley, AD Murray, MA Nalls, EK Nang, CP Nelson, S Nona, JM Norris, CV Nwuba, J O'Connell, ND Palmer, GJ Papanicolau, R Pazoki, NL Pedersen, A Peters, PA Peyser, O Polasek, DJ Porteous, A Poveda, OT Raitakari, SS Rich, N Risch, JG Robinson, LM Rose, I Rudan, PJ Schreiner, RA Scott, SS Sidney, M Sims, JA Smith, H Snieder, T Sofer, JM Starr, B Sternfeld, K Strauch, H Tang, KD Taylor, MY Tsai, J Tuomilehto, AG Uitterlinden, MY van der Ende, D van Heemst, T Voortman, M Waldenberger, P Wennberg, G Wilson, YB Xiang, J Yao, C Yu, JM Yuan, W Zhao, AB Zonderman, DM Becker, M Boehnke, DW Bowden, U de Faire, IJ Deary, P Elliott, T Esko, BI Freedman, P Froguel, P Gasparini, C Gieger, N Kato, M Laakso, TA Lakka, T Lehtimäki, PKE Magnusson, AJ Oldehinkel, BWJH Penninx, NJ Samani, XO Shu, P van der Harst, JV Van Vliet-Ostaptchouk, P Vollenweider, LE Wagenknecht, YX Wang, NJ Wareham, DR Weir, T Wu, W Zheng, X Zhu, MK Evans, PW Franks, V Gudnason, C Hayward, BL Horta, TN Kelly, Y Liu, KE North, AC Pereira, PM Ridker, ES Tai, RM van Dam, ER Fox, SLR Kardia, CT Liu, DO Mook-Kanamori, MA Province, S Redline, CM van Duijn, JI Rotter, CB Kooperberg, WJ Gauderman, BM Psaty, K Rice, PB Munroe, M Fornage, LA Cupples, CN Rotimi, AC Morrison, DC Rao, RJF Loos

Publication Date: 2019-01-22

Variant appearance in text: rs12654264

PubMed Link: 30670697

Variant Present in the following documents:

• 41467_2018_8008_MOESM11_ESM.xlsx
• 41467_2018_8008_MOESM8_ESM.xlsx

View BVdb publication page

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Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

American Journal Of Human Genetics

AT Kraja, C Liu, JL Fetterman, M Graff, CT Have, C Gu, LR Yanek, MF Feitosa, DE Arking, DI Chasman, K Young, S Ligthart, WD Hill, S Weiss, J Luan, F Giulianini, R Li-Gao, FP Hartwig, SJ Lin, L Wang, TG Richardson, J Yao, EP Fernandez, M Ghanbari, MK Wojczynski, WJ Lee, M Argos, SM Armasu, RA Barve, KA Ryan, P An, TJ Baranski, SJ Bielinski, DW Bowden, U Broeckel, K Christensen, AY Chu, J Corley, SR Cox, AG Uitterlinden, F Rivadeneira, CD Cropp, EW Daw, D van Heemst, L de Las Fuentes, H Gao, I Tzoulaki, TS Ahluwalia, R de Mutsert, LS Emery, AM Erzurumluoglu, JA Perry, M Fu, NG Forouhi, Z Gu, Y Hai, SE Harris, G Hemani, SC Hunt, MR Irvin, AE Jonsson, AE Justice, ND Kerrison, NB Larson, KH Lin, LD Love-Gregory, RA Mathias, JH Lee, M Nauck, R Noordam, KK Ong, J Pankow, A Patki, A Pattie, A Petersmann, Q Qi, R Ribel-Madsen, R Rohde, K Sandow, TM Schnurr, T Sofer, JM Starr, AM Taylor, A Teumer, NJ Timpson, HG de Haan, Y Wang, PE Weeke, C Williams, H Wu, W Yang, D Zeng, DR Witte, BS Weir, NJ Wareham, H Vestergaard, ST Turner, C Torp-Pedersen, E Stergiakouli, WH Sheu, FR Rosendaal, MA Ikram, OH Franco, PM Ridker, TT Perls, O Pedersen, EA Nohr, AB Newman, A Linneberg, C Langenberg, TO Kilpeläinen, SLR Kardia, ME Jørgensen, T Jørgensen, TIA Sørensen, G Homuth, T Hansen, MO Goodarzi, IJ Deary, C Christensen, YI Chen, A Chakravarti, I Brandslund, K Bonnelykke, KD Taylor, JG Wilson, S Rodriguez, G Davies, BL Horta, B Thyagarajan, DC Rao, N Grarup, VG Davila-Roman, G Hudson, X Guo, DK Arnett, C Hayward, D Vaidya, DO Mook-Kanamori, HK Tiwari, D Levy, RJF Loos, A Dehghan, P Elliott, AN Malik, RA Scott, DM Becker, M de Andrade, MA Province, JB Meigs, JI Rotter, KE North

Publication Date: 2019-01-03

Variant appearance in text: rs12654264

PubMed Link: 30595373

Variant Present in the following documents:

• Main text

View BVdb publication page

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The role of genetic variation of human metabolism for BMI, mental traits and mental disorders.

Molecular Metabolism

J Hebebrand, T Peters, D Schijven, M Hebebrand, C Grasemann, TW Winkler, IM Heid, J Antel, M Föcker, L Tegeler, L Brauner, RAH Adan, JJ Luykx, CU Correll, IR König, A Hinney, L Libuda

Publication Date: 2018-06

Variant appearance in text: rs12654264

PubMed Link: 29673576

Variant Present in the following documents:

• Main text
• mmc1.xlsx

View BVdb publication page

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A Genome-Wide Association Study Identifies a Candidate Gene Associated With Atazanavir Exposure Measured in Hair.

Clinical Pharmacology And Therapeutics

B Tamraz, Y Huang, AL French, S Kassaye, K Anastos, MJ Nowicki, S Gange, DR Gustafson, P Bacchetti, RM Greenblatt, PG Hysi, BE Aouizerat

Publication Date: 2018-11

Variant appearance in text: rs12654264

PubMed Link: 29315502

Variant Present in the following documents:

• NIHMS933666-supplement-Supp_TableS3.docx

View BVdb publication page

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Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.

Plos Genetics

JP Davis, JR Huyghe, AE Locke, AU Jackson, X Sim, HM Stringham, TM Teslovich, RP Welch, C Fuchsberger, N Narisu, PS Chines, AJ Kangas, P Soininen, M Ala-Korpela, J Kuusisto, FS Collins, M Laakso, M Boehnke, KL Mohlke

Publication Date: 2017-10

Variant appearance in text: rs12654264

PubMed Link: 29084231

Variant Present in the following documents:

• pgen.1007079.s010.xlsx

View BVdb publication page

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Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.

Nature Genetics

X Lu, GM Peloso, DJ Liu, Y Wu, H Zhang, W Zhou, J Li, CS Tang, R Dorajoo, H Li, J Long, X Guo, M Xu, CN Spracklen, Y Chen, X Liu, Y Zhang, CC Khor, J Liu, L Sun, L Wang, YT Gao, Y Hu, K Yu, Y Wang, CYY Cheung, F Wang, J Huang, Q Fan, Q Cai, S Chen, J Shi, X Yang, W Zhao, WH Sheu, SS Cherny, M He, AB Feranil, LS Adair, P Gordon-Larsen, S Du, R Varma, YI Chen, XO Shu, KSL Lam, TY Wong, SK Ganesh, Z Mo, K Hveem, LG Fritsche, JB Nielsen, HF Tse, Y Huo, CY Cheng, YE Chen, W Zheng, ES Tai, W Gao, X Lin, W Huang, G Abecasis, , S Kathiresan, KL Mohlke, T Wu, PC Sham, D Gu, CJ Willer

Publication Date: 2017-12

Variant appearance in text: rs12654264

PubMed Link: 29083407

Variant Present in the following documents:

• NIHMS909133-supplement-2.xlsx

View BVdb publication page

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The effect of genetic variants on the relationship between statins and breast cancer in postmenopausal women in the Women's Health Initiative observational study.

Breast Cancer Research And Treatment

CH Bock, AM Jay, G Dyson, JL Beebe-Dimmer, ML Cote, L Hou, BV Howard, P Desai, K Purrington, R Prentice, MS Simon

Publication Date: 2018-02

Variant appearance in text: rs12654264

PubMed Link: 29063981

Variant Present in the following documents:

• Main text

View BVdb publication page

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Potentiating the effects of radiotherapy in rectal cancer: the role of aspirin, statins and metformin as adjuncts to therapy.

British Journal Of Cancer

KJ Gash, AC Chambers, DE Cotton, AC Williams, MG Thomas

Publication Date: 2017-07-11

Variant appearance in text: rs12654264

PubMed Link: 28641310

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.

Lipids In Health And Disease

CS Paththinige, ND Sirisena, V Dissanayake

Publication Date: 2017-06-02

Variant appearance in text: rs12654264

PubMed Link: 28577571

Variant Present in the following documents:

• 12944_2017_488_MOESM1_ESM.xlsx
• aaaaaMain text

View BVdb publication page

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Low LDL cholesterol, PCSK9 and HMGCR genetic variation, and risk of Alzheimer's disease and Parkinson's disease: Mendelian randomisation study.

Bmj (Clinical Research Ed.)

M Benn, BG Nordestgaard, R Frikke-Schmidt, A Tybjærg-Hansen

Publication Date: 2017-04-24

Variant appearance in text: rs12654264

PubMed Link: 28438747

Variant Present in the following documents:

• benm033277.ww1.pdf

View BVdb publication page

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GRECOS Project (Genotyping Recurrence Risk of Stroke): The Use of Genetics to Predict the Vascular Recurrence After Stroke.

Stroke

I Fernández-Cadenas, M Mendióroz, D Giralt, C Nafria, E Garcia, C Carrera, C Gallego-Fabrega, S Domingues-Montanari, P Delgado, M Ribó, M Castellanos, S Martínez, M Freijo, J Jiménez-Conde, M Rubiera, J Alvarez-Sabín, CA Molina, MA Font, M Grau Olivares, E Palomeras, N Perez de la Ossa, M Martinez-Zabaleta, J Masjuan, F Moniche, D Canovas, C Piñana, F Purroy, D Cocho, I Navas, C Tejero, N Aymerich, N Cullell, E Muiño, J Serena, F Rubio, A Davalos, J Roquer, JF Arenillas, J Martí-Fábregas, K Keene, WM Chen, B Worrall, M Sale, A Arboix, J Krupinski, J Montaner,

Publication Date: 2017-05

Variant appearance in text: rs12654264

PubMed Link: 28411264

Variant Present in the following documents:

• NIHMS861713-supplement-Supplemental_Material.pdf

View BVdb publication page

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Identification of STXBP2 as a novel susceptibility locus for myocardial infarction in Japanese individuals by an exome-wide association study.

Oncotarget

Y Yamada, J Sakuma, I Takeuchi, Y Yasukochi, K Kato, M Oguri, T Fujimaki, H Horibe, M Muramatsu, M Sawabe, Y Fujiwara, Y Taniguchi, S Obuchi, H Kawai, S Shinkai, S Mori, T Arai, M Tanaka

Publication Date: 2017-05-16

Variant appearance in text: rs12654264

PubMed Link: 28380445

Variant Present in the following documents:

• oncotarget-08-33527-s002.docx

View BVdb publication page

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Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.

Journal Of Cellular And Molecular Medicine

Y Zhu, D Zhang, D Zhou, Z Li, Z Li, L Fang, M Yang, Z Shan, H Li, J Chen, X Zhou, W Ye, S Yu, H Li, L Cai, C Liu, J Zhang, L Wang, Y Lai, L Ruan, Z Sun, S Zhang, H Wang, Y Liu, Y Xu, J Ling, C Xu, Y Zhang, D Lv, Z Yuan, J Zhang, Y Zhang, Y Shi, M Lai

Publication Date: 2017-06

Variant appearance in text: rs12654264

PubMed Link: 28371326

Variant Present in the following documents:

• JCMM-21-1106-s002.xlsx

View BVdb publication page

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Genetic associations with lipoprotein subfraction measures differ by ethnicity in the multi-ethnic study of atherosclerosis (MESA).

Human Genetics

Z Wang, A Manichukal, DC Goff, S Mora, JM Ordovas, NM Pajewski, WS Post, JI Rotter, MM Sale, SA Santorico, D Siscovick, MY Tsai, DK Arnett, S Rich, AC Frazier-Wood

Publication Date: 2017-06

Variant appearance in text: rs12654264

PubMed Link: 28352986

Variant Present in the following documents:

• 439_2017_1782_MOESM1_ESM.docx

View BVdb publication page

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Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.

Genome Medicine

R Nagy, TS Boutin, J Marten, JE Huffman, SM Kerr, A Campbell, L Evenden, J Gibson, C Amador, DM Howard, P Navarro, A Morris, IJ Deary, LJ Hocking, S Padmanabhan, BH Smith, P Joshi, JF Wilson, ND Hastie, AF Wright, AM McIntosh, DJ Porteous, CS Haley, V Vitart, C Hayward

Publication Date: 2017-03-07

Variant appearance in text: rs12654264

PubMed Link: 28270201

Variant Present in the following documents:

• 13073_2017_414_MOESM11_ESM.xlsx

View BVdb publication page

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Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits.

American Journal Of Human Genetics

M Civelek, Y Wu, C Pan, CK Raulerson, A Ko, A He, C Tilford, NK Saleem, A Stančáková, LJ Scott, C Fuchsberger, HM Stringham, AU Jackson, N Narisu, PS Chines, KS Small, J Kuusisto, BW Parks, P Pajukanta, T Kirchgessner, FS Collins, PS Gargalovic, M Boehnke, M Laakso, KL Mohlke, AJ Lusis

Publication Date: 2017-03-02

Variant appearance in text: rs12654264

PubMed Link: 28257690

Variant Present in the following documents:

• mmc3.xlsx

View BVdb publication page

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Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.

Nature Genetics

V Iotchkova, J Huang, JA Morris, D Jain, C Barbieri, K Walter, JL Min, L Chen, W Astle, M Cocca, P Deelen, H Elding, AE Farmaki, CS Franklin, M Franberg, TR Gaunt, A Hofman, T Jiang, ME Kleber, G Lachance, J Luan, G Malerba, A Matchan, D Mead, Y Memari, I Ntalla, K Panoutsopoulou, R Pazoki, JRB Perry, F Rivadeneira, M Sabater-Lleal, B Sennblad, SY Shin, L Southam, M Traglia, F van Dijk, EM van Leeuwen, G Zaza, W Zhang, , N Amin, A Butterworth, JC Chambers, G Dedoussis, A Dehghan, OH Franco, L Franke, M Frontini, G Gambaro, P Gasparini, A Hamsten, A Issacs, JS Kooner, C Kooperberg, C Langenberg, W Marz, RA Scott, MA Swertz, D Toniolo, AG Uitterlinden, CM van Duijn, H Watkins, E Zeggini, MT Maurano, NJ Timpson, AP Reiner, PL Auer, N Soranzo

Publication Date: 2016-11

Variant appearance in text: rs12654264

PubMed Link: 27668658

Variant Present in the following documents:

• NIHMS71079-supplement-Supplementary_Data.pdf

View BVdb publication page

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Phase I biomarker modulation study of atorvastatin in women at increased risk for breast cancer.

Breast Cancer Research And Treatment

BK Arun, Y Gong, D Liu, JK Litton, AM Gutierrez-Barrera, J Jack Lee, L Vornik, NK Ibrahim, T Cornelison, GN Hortobagyi, BM Heckman-Stoddard, KB Koenig, RR Alvarez, JL Murray, V Valero, SM Lippman, P Brown, N Sneige

Publication Date: 2016-07

Variant appearance in text: rs12654264

PubMed Link: 27287781

Variant Present in the following documents:

• Main text

View BVdb publication page

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Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk.

Human Genetics

V Tragante, FW Asselbergs, DI Swerdlow, TM Palmer, JH Moore, PIW de Bakker, BJ Keating, MV Holmes

Publication Date: 2016-05

Variant appearance in text: rs12654264

PubMed Link: 26946290

Variant Present in the following documents:

• Main text

View BVdb publication page

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Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools.

Molecular Metabolism

AK Teo, MK Gupta, A Doria, RN Kulkarni

Publication Date: 2015-09

Variant appearance in text: rs12654264

PubMed Link: 26413465

Variant Present in the following documents:

• Main text

View BVdb publication page

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Evaluation of transethnic fine mapping with population-specific and cosmopolitan imputation reference panels in diverse Asian populations.

European Journal Of Human Genetics : Ejhg

X Wang, CY Cheng, J Liao, X Sim, J Liu, KS Chia, ES Tai, P Little, CC Khor, T Aung, TY Wong, YY Teo

Publication Date: 2016-04

Variant appearance in text: rs12654264

PubMed Link: 26130488

Variant Present in the following documents:

• ejhg2015150x4.xls

View BVdb publication page

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Apolipoprotein E and protection against hepatitis E viral infection in American non-Hispanic blacks.

Hepatology (Baltimore, Md.)

L Zhang, A Yesupriya, MH Chang, E Teshale, CG Teo

Publication Date: 2015-11

Variant appearance in text: rs12654264

PubMed Link: 26096528

Variant Present in the following documents:

• NIHMS1043972-supplement-Supplemental.pdf

View BVdb publication page

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Evidence for Clinical Implementation of Pharmacogenomics in Cardiac Drugs.

Mayo Clinic Proceedings

AL Kaufman, J Spitz, M Jacobs, M Sorrentino, S Yuen, K Danahey, D Saner, TE Klein, RB Altman, MJ Ratain, PH O'Donnell

Publication Date: 2015-06

Variant appearance in text: rs12654264

PubMed Link: 26046407

Variant Present in the following documents:

• NIHMS676556-supplement-4.pdf

View BVdb publication page

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A genome-wide pleiotropy scan for prostate cancer risk.

European Urology

OA Panagiotou, RC Travis, D Campa, SI Berndt, S Lindstrom, P Kraft, FR Schumacher, A Siddiq, SI Papatheodorou, JL Stanford, D Albanes, J Virtamo, SJ Weinstein, WR Diver, SM Gapstur, VL Stevens, H Boeing, HB Bueno-de-Mesquita, A Barricarte Gurrea, R Kaaks, KT Khaw, V Krogh, K Overvad, E Riboli, D Trichopoulos, E Giovannucci, M Stampfer, C Haiman, B Henderson, L Le Marchand, JM Gaziano, DJ Hunter, S Koutros, M Yeager, RN Hoover, , SJ Chanock, S Wacholder, TJ Key, KK Tsilidis

Publication Date: 2015-04

Variant appearance in text: rs12654264

PubMed Link: 25277271

Variant Present in the following documents:

• NIHMS628904-supplement-Suppl__1.doc

View BVdb publication page

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HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.

Lancet (London, England)

DI Swerdlow, D Preiss, KB Kuchenbaecker, MV Holmes, JE Engmann, T Shah, R Sofat, S Stender, PC Johnson, RA Scott, M Leusink, N Verweij, SJ Sharp, Y Guo, C Giambartolomei, C Chung, A Peasey, A Amuzu, K Li, J Palmen, P Howard, JA Cooper, F Drenos, YR Li, G Lowe, J Gallacher, MC Stewart, I Tzoulaki, SG Buxbaum, DL van der A, NG Forouhi, NC Onland-Moret, YT van der Schouw, RB Schnabel, JA Hubacek, R Kubinova, M Baceviciene, A Tamosiunas, A Pajak, R Topor-Madry, U Stepaniak, S Malyutina, D Baldassarre, B Sennblad, E Tremoli, U de Faire, F Veglia, I Ford, JW Jukema, RG Westendorp, GJ de Borst, PA de Jong, A Algra, W Spiering, AH Maitland-van der Zee, OH Klungel, A de Boer, PA Doevendans, CB Eaton, JG Robinson, D Duggan, , , , J Kjekshus, JR Downs, AM Gotto, AC Keech, R Marchioli, G Tognoni, PS Sever, NR Poulter, DD Waters, TR Pedersen, P Amarenco, H Nakamura, JJ McMurray, JD Lewsey, DI Chasman, PM Ridker, AP Maggioni, L Tavazzi, KK Ray, SR Seshasai, JE Manson, JF Price, PH Whincup, RW Morris, DA Lawlor, GD Smith, Y Ben-Shlomo, PJ Schreiner, M Fornage, DS Siscovick, M Cushman, M Kumari, NJ Wareham, WM Verschuren, S Redline, SR Patel, JC Whittaker, A Hamsten, JA Delaney, C Dale, TR Gaunt, A Wong, D Kuh, R Hardy, S Kathiresan, BA Castillo, P van der Harst, EJ Brunner, A Tybjaerg-Hansen, MG Marmot, RM Krauss, M Tsai, J Coresh, RC Hoogeveen, BM Psaty, LA Lange, H Hakonarson, F Dudbridge, SE Humphries, PJ Talmud, M Kivimäki, NJ Timpson, C Langenberg, FW Asselbergs, M Voevoda, M Bobak, H Pikhart, JG Wilson, AP Reiner, BJ Keating, AD Hingorani, N Sattar

Publication Date: 2015-01-24

Variant appearance in text: rs12654264

PubMed Link: 25262344

Variant Present in the following documents:

• mmc1.pdf

View BVdb publication page

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Screening for 392 polymorphisms in 141 pharmacogenes.

Biomedical Reports

JY Kim, HS Cheong, TJ Park, HJ Shin, DW Seo, HS Na, MW Chung, HD Shin

Publication Date: 2014-07

Variant appearance in text: rs12654264

PubMed Link: 24944790

Variant Present in the following documents:

• Main text

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Association of genetic variants with rapid fibrosis: progression after liver transplantation for hepatitis C.

Transplantation

JE Layden, BO Tayo, SJ Cotler, NM Clark, K Baraoidan, SL Friedman, RS Cooper

Publication Date: 2014-05-27

Variant appearance in text: rs12654264

PubMed Link: 24770613

Variant Present in the following documents:

• Main text
• NIHMS710967-supplement-Supplemental_file.pdf

View BVdb publication page

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Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study.

Circulation. Cardiovascular Genetics

JM Kocarnik, SA Pendergrass, CL Carty, JS Pankow, FR Schumacher, I Cheng, P Durda, JL Ambite, E Deelman, NR Cook, S Liu, J Wactawski-Wende, C Hutter, K Brown-Gentry, S Wilson, LG Best, N Pankratz, CP Hong, SA Cole, VS Voruganti, P Bůžkova, NW Jorgensen, NS Jenny, LR Wilkens, CA Haiman, LN Kolonel, A Lacroix, K North, R Jackson, L Le Marchand, LA Hindorff, DC Crawford, M Gross, U Peters

Publication Date: 2014-04

Variant appearance in text: rs12654264

PubMed Link: 24622110

Variant Present in the following documents:

• NIHMS575195-supplement-000173_-_Supplemental_Material.pdf

View BVdb publication page

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Evaluation of the effect of genetic variation on the relationship between statins, cardiovascular disease and cancer.

International Journal Of Molecular Epidemiology And Genetics

P Desai, A Jay, C Bock, G Dyson, T Okwuosa, MS Simon

Publication Date: 2013-11-28

Variant appearance in text: rs12654264

PubMed Link: 24319534

Variant Present in the following documents:

• Main text

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Biobanking across the phenome - at the center of chronic disease research.

Bmc Public Health

M Imboden, NM Probst-Hensch

Publication Date: 2013-11-25

Variant appearance in text: rs12654264

PubMed Link: 24274136

Variant Present in the following documents:

• 1471-2458-13-1094-S2.xlsx

View BVdb publication page

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ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer.

Bmc Medical Genomics

M Bysani, O Wallerman, S Bornelöv, K Zatloukal, J Komorowski, C Wadelius

Publication Date: 2013-11-08

Variant appearance in text: rs12654264

PubMed Link: 24206787

Variant Present in the following documents:

• 1755-8794-6-50-S2.docx

View BVdb publication page

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A clinical trial of lovastatin for modification of biomarkers associated with breast cancer risk.

Breast Cancer Research And Treatment

S Vinayak, EJ Schwartz, K Jensen, J Lipson, E Alli, L McPherson, AM Fernandez, VB Sharma, A Staton, MA Mills, EA Schackmann, ML Telli, A Kardashian, JM Ford, AW Kurian

Publication Date: 2013-11

Variant appearance in text: rs12654264

PubMed Link: 24166281

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations.

Cerebrovascular Diseases (Basel, Switzerland)

SY Chou, JM Shulman, BT Keenan, EA Secor, AS Buchman, J Schneider, DA Bennett, PL De Jager

Publication Date: 2013

Variant appearance in text: rs12654264

PubMed Link: 24135527

Variant Present in the following documents:

• NIHMS527173-supplement-01.pdf

View BVdb publication page

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No evidence of interaction between known lipid-associated genetic variants and smoking in the multi-ethnic PAGE population.

Human Genetics

L Dumitrescu, CL Carty, N Franceschini, LA Hindorff, SA Cole, P Bůžková, FR Schumacher, CB Eaton, RJ Goodloe, DJ Duggan, J Haessler, B Cochran, BE Henderson, I Cheng, KC Johnson, CS Carlson, SA Love, K Brown-Gentry, AQ Nato, M Quibrera, RV Shohet, JL Ambite, LR Wilkens, L Le Marchand, CA Haiman, S Buyske, C Kooperberg, KE North, M Fornage, DC Crawford

Publication Date: 2013-12

Variant appearance in text: rs12654264

PubMed Link: 24100633

Variant Present in the following documents:

• Main text
• NIHMS530028-supplement-439_2013_1375_MOESM1_ESM.docx

View BVdb publication page

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Progress and future aspects in genetics of human hypertension.

Current Hypertension Reports

Q Zhao, TN Kelly, C Li, J He

Publication Date: 2013-12

Variant appearance in text: rs12654264

PubMed Link: 24072558

Variant Present in the following documents:

• Main text

View BVdb publication page

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Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study.

Plos Biology

CS Carlson, TC Matise, KE North, CA Haiman, MD Fesinmeyer, S Buyske, FR Schumacher, U Peters, N Franceschini, MD Ritchie, DJ Duggan, KL Spencer, L Dumitrescu, CB Eaton, F Thomas, A Young, C Carty, G Heiss, L Le Marchand, DC Crawford, LA Hindorff, CL Kooperberg,

Publication Date: 2013-09

Variant appearance in text: rs12654264

PubMed Link: 24068893

Variant Present in the following documents:

• pbio.1001661.s003.xlsx
• pbio.1001661.s004.xlsx

View BVdb publication page

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Properties of local interactions and their potential value in complementing genome-wide association studies.

Plos One

W Wei, A Gyenesei, CA Semple, CS Haley

Publication Date: 2013

Variant appearance in text: rs12654264

PubMed Link: 23940718

Variant Present in the following documents:

• pone.0071203.s003.xlsx

View BVdb publication page

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Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study.

Bmc Genetics

KC Taylor, CL Carty, L Dumitrescu, P Bůžková, SA Cole, L Hindorff, FR Schumacher, LR Wilkens, RV Shohet, PM Quibrera, KC Johnson, BE Henderson, J Haessler, N Franceschini, CB Eaton, DJ Duggan, B Cochran, I Cheng, CS Carlson, K Brown-Gentry, G Anderson, JL Ambite, C Haiman, L Le Marchand, C Kooperberg, DC Crawford, S Buyske, KE North, M Fornage,

Publication Date: 2013-05-01

Variant appearance in text: rs12654264

PubMed Link: 23634756

Variant Present in the following documents:

• 1471-2156-14-33-S1.pdf
• aaaaaMain text

View BVdb publication page

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Genetic variants from lipid-related pathways and risk for incident myocardial infarction.

Plos One

C Song, NL Pedersen, CA Reynolds, M Sabater-Lleal, S Kanoni, C Willenborg, , AC Syvänen, H Watkins, A Hamsten, JA Prince, E Ingelsson

Publication Date: 2013

Variant appearance in text: rs12654264

PubMed Link: 23555974

Variant Present in the following documents:

• pone.0060454.s001.pdf

View BVdb publication page

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Improvement in prediction of coronary heart disease risk over conventional risk factors using SNPs identified in genome-wide association studies.

Plos One

JL Bolton, MC Stewart, JF Wilson, N Anderson, JF Price

Publication Date: 2013

Variant appearance in text: rs12654264

PubMed Link: 23468967

Variant Present in the following documents:

• pone.0057310.s005.pdf

View BVdb publication page

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Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network.

Plos Genetics

SA Pendergrass, K Brown-Gentry, S Dudek, A Frase, ES Torstenson, R Goodloe, JL Ambite, CL Avery, S Buyske, P Bůžková, E Deelman, MD Fesinmeyer, CA Haiman, G Heiss, LA Hindorff, CN Hsu, RD Jackson, C Kooperberg, L Le Marchand, Y Lin, TC Matise, KR Monroe, L Moreland, SL Park, A Reiner, R Wallace, LR Wilkens, DC Crawford, MD Ritchie

Publication Date: 2013

Variant appearance in text: rs12654264

PubMed Link: 23382687

Variant Present in the following documents:

• pgen.1003087.s001.xlsx

View BVdb publication page

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Identification of novel type 2 diabetes candidate genes involved in the crosstalk between the mitochondrial and the insulin signaling systems.

Plos Genetics

JM Mercader, M Puiggros, AV Segrè, E Planet, E Sorianello, D Sebastian, S Rodriguez-Cuenca, V Ribas, S Bonàs-Guarch, S Draghici, C Yang, S Mora, A Vidal-Puig, J Dupuis, , JC Florez, , A Zorzano, D Torrents

Publication Date: 2012

Variant appearance in text: rs12654264

PubMed Link: 23236286

Variant Present in the following documents:

• pgen.1003046.s009.doc

View BVdb publication page

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Effect of genetic predisposition on blood lipid traits using cumulative risk assessment in the korean population.

Genomics & Informatics

MJ Go, JY Hwang, DJ Kim, HJ Lee, HB Jang, KH Park, J Song, JY Lee

Publication Date: 2012-06

Variant appearance in text: rs12654264

PubMed Link: 23105936

Variant Present in the following documents:

• Main text

View BVdb publication page

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Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

American Journal Of Human Genetics

FW Asselbergs, Y Guo, EP van Iperen, S Sivapalaratnam, V Tragante, MB Lanktree, LA Lange, B Almoguera, YE Appelman, J Barnard, J Baumert, AL Beitelshees, TR Bhangale, YD Chen, TR Gaunt, Y Gong, JC Hopewell, T Johnson, ME Kleber, TY Langaee, M Li, YR Li, K Liu, CW McDonough, MF Meijs, RP Middelberg, K Musunuru, CP Nelson, JR O'Connell, S Padmanabhan, JS Pankow, N Pankratz, S Rafelt, R Rajagopalan, SP Romaine, NJ Schork, J Shaffer, H Shen, EN Smith, SE Tischfield, PJ van der Most, JV van Vliet-Ostaptchouk, N Verweij, KA Volcik, L Zhang, KR Bailey, KM Bailey, F Bauer, JM Boer, PS Braund, A Burt, PR Burton, SG Buxbaum, W Chen, RM Cooper-Dehoff, LA Cupples, JS deJong, C Delles, D Duggan, M Fornage, CE Furlong, N Glazer, JG Gums, C Hastie, MV Holmes, T Illig, SA Kirkland, M Kivimaki, R Klein, BE Klein, C Kooperberg, K Kottke-Marchant, M Kumari, AZ LaCroix, L Mallela, G Murugesan, J Ordovas, WH Ouwehand, WS Post, R Saxena, H Scharnagl, PJ Schreiner, T Shah, DC Shields, D Shimbo, SR Srinivasan, RP Stolk, DI Swerdlow, HA Taylor, EJ Topol, E Toskala, JL van Pelt, J van Setten, S Yusuf, JC Whittaker, AH Zwinderman, , SS Anand, AJ Balmforth, GS Berenson, CR Bezzina, BO Boehm, E Boerwinkle, JP Casas, MJ Caulfield, R Clarke, JM Connell, KJ Cruickshanks, KW Davidson, IN Day, PI de Bakker, PA Doevendans, AF Dominiczak, AS Hall, CA Hartman, C Hengstenberg, HL Hillege, MH Hofker, SE Humphries, GP Jarvik, JA Johnson, BM Kaess, S Kathiresan, W Koenig, DA Lawlor, W März, O Melander, BD Mitchell, GW Montgomery, PB Munroe, SS Murray, SJ Newhouse, NC Onland-Moret, N Poulter, B Psaty, S Redline, SS Rich, JI Rotter, H Schunkert, P Sever, AR Shuldiner, RL Silverstein, A Stanton, B Thorand, MD Trip, MY Tsai, P van der Harst, E van der Schoot, YT van der Schouw, WM Verschuren, H Watkins, AA Wilde, BH Wolffenbuttel, JB Whitfield, GK Hovingh, CM Ballantyne, C Wijmenga, MP Reilly, NG Martin, JG Wilson, DJ Rader, NJ Samani, AP Reiner, RA Hegele, JJ Kastelein, AD Hingorani, PJ Talmud, H Hakonarson, CC Elbers, BJ Keating, F Drenos

Publication Date: 2012-11-02

Variant appearance in text: rs12654264

PubMed Link: 23063622

Variant Present in the following documents:

• mmc4.xls
• mmc7.xls

View BVdb publication page

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Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals.

Plos One

F Takeuchi, M Isono, T Katsuya, M Yokota, K Yamamoto, T Nabika, K Shimokawa, E Nakashima, T Sugiyama, H Rakugi, S Yamaguchi, T Ogihara, Y Yamori, N Kato

Publication Date: 2012

Variant appearance in text: rs12654264

PubMed Link: 23050023

Variant Present in the following documents:

• pone.0046385.s002.xls

View BVdb publication page

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Polymorphisms in the fetal progesterone receptor and a calcium-activated potassium channel isoform are associated with preterm birth in an Argentinian population.

Journal Of Perinatology : Official Journal Of The California Perinatal Association

PC Mann, ME Cooper, KK Ryckman, B Comas, J Gili, S Crumley, EN Bream, HM Byers, T Piester, A Schaefer, PJ Christine, A Lawrence, KL Schaa, KJ Kelsey, SK Berends, AM Momany, E Gadow, V Cosentino, EE Castilla, J López Camelo, C Saleme, LJ Day, SK England, ML Marazita, JM Dagle, JC Murray

Publication Date: 2013-05

Variant appearance in text: rs12654264

PubMed Link: 23018797

Variant Present in the following documents:

• Main text

View BVdb publication page

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Low-density lipoprotein cholesterol, apolipoprotein B, and risk of coronary heart disease: from familial hyperlipidemia to genomics.

Biological Research For Nursing

CC Imes, MA Austin

Publication Date: 2013-07

Variant appearance in text: rs12654264

PubMed Link: 22531366

Variant Present in the following documents:

• Main text

View BVdb publication page

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Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain.

Neurobiology Of Disease

DG Hernandez, MA Nalls, M Moore, S Chong, A Dillman, D Trabzuni, JR Gibbs, M Ryten, S Arepalli, ME Weale, AB Zonderman, J Troncoso, R O'Brien, R Walker, C Smith, S Bandinelli, BJ Traynor, J Hardy, AB Singleton, MR Cookson

Publication Date: 2012-07

Variant appearance in text: rs12654264

PubMed Link: 22433082

Variant Present in the following documents:

• mmc1.xls

View BVdb publication page

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Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study.

Circulation. Cardiovascular Genetics

CL Carty, P Buzková, M Fornage, N Franceschini, S Cole, G Heiss, LA Hindorff, BV Howard, S Mann, LW Martin, Y Zhang, TC Matise, R Prentice, AP Reiner, C Kooperberg

Publication Date: 2012-04-01

Variant appearance in text: rs12654264

PubMed Link: 22403240

Variant Present in the following documents:

• NIHMS369440-supplement-01.pdf

View BVdb publication page

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A short-term biomarker modulation study of simvastatin in women at increased risk of a new breast cancer.

Breast Cancer Research And Treatment

MJ Higgins, TM Prowell, AL Blackford, C Byrne, NF Khouri, SA Slater, SC Jeter, DK Armstrong, NE Davidson, LA Emens, JH Fetting, PP Powers, AC Wolff, H Green, JN Thibert, JM Rae, E Folkerd, M Dowsett, RS Blumenthal, JE Garber, V Stearns

Publication Date: 2012-02

Variant appearance in text: rs12654264

PubMed Link: 22076478

Variant Present in the following documents:

• Main text

View BVdb publication page

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A genome-wide scan for common variants affecting the rate of age-related cognitive decline.

Neurobiology Of Aging

PL De Jager, JM Shulman, LB Chibnik, BT Keenan, T Raj, RS Wilson, L Yu, SE Leurgans, D Tran, C Aubin, CD Anderson, A Biffi, JJ Corneveaux, MJ Huentelman, , J Rosand, MJ Daly, AJ Myers, EM Reiman, DA Bennett, DA Evans

Publication Date: 2012-05

Variant appearance in text: rs12654264

PubMed Link: 22054870

Variant Present in the following documents:

• NIHMS328602-supplement-01.doc

View BVdb publication page

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Implications of discoveries from genome-wide association studies in current cardiovascular practice.

World Journal Of Cardiology

P Jeemon, K Pettigrew, C Sainsbury, D Prabhakaran, S Padmanabhan

Publication Date: 2011-07-26

Variant appearance in text: rs12654264

PubMed Link: 21860704

Variant Present in the following documents:

• Main text

View BVdb publication page

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Evidence for age as a modifier of genetic associations for lipid levels.

Annals Of Human Genetics

L Dumitrescu, K Brown-Gentry, R Goodloe, K Glenn, W Yang, N Kornegay, CH Pui, MV Relling, DC Crawford

Publication Date: 2011-09

Variant appearance in text: rs12654264

PubMed Link: 21777205

Variant Present in the following documents:

• NIHMS304382-supplement-Supp_Table_S1-S4.doc

View BVdb publication page

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Genetic variability within the cholesterol lowering pathway and the effectiveness of statins in reducing the risk of MI.

Atherosclerosis

BJ Peters, H Pett, OH Klungel, BH Stricker, BM Psaty, NL Glazer, KL Wiggins, JC Bis, A de Boer, AH Maitland-van der Zee

Publication Date: 2011-08

Variant appearance in text: rs12654264

PubMed Link: 21741043

Variant Present in the following documents:

• NIHMS310676-supplement-01.doc

View BVdb publication page

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Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study.

Plos Genetics

L Dumitrescu, CL Carty, K Taylor, FR Schumacher, LA Hindorff, JL Ambite, G Anderson, LG Best, K Brown-Gentry, P Bůžková, CS Carlson, B Cochran, SA Cole, RB Devereux, D Duggan, CB Eaton, M Fornage, N Franceschini, J Haessler, BV Howard, KC Johnson, S Laston, LN Kolonel, ET Lee, JW MacCluer, TA Manolio, SA Pendergrass, M Quibrera, RV Shohet, LR Wilkens, CA Haiman, L Le Marchand, S Buyske, C Kooperberg, KE North, DC Crawford

Publication Date: 2011-06

Variant appearance in text: rs12654264

PubMed Link: 21738485

Variant Present in the following documents:

• Main text
• pgen.1002138.s015.doc
• pgen.1002138.s016.docx

View BVdb publication page

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Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.

Plos Genetics

G Lettre, CD Palmer, T Young, KG Ejebe, H Allayee, EJ Benjamin, F Bennett, DW Bowden, A Chakravarti, A Dreisbach, DN Farlow, AR Folsom, M Fornage, T Forrester, E Fox, CA Haiman, J Hartiala, TB Harris, SL Hazen, SR Heckbert, BE Henderson, JN Hirschhorn, BJ Keating, SB Kritchevsky, E Larkin, M Li, ME Rudock, CA McKenzie, JB Meigs, YA Meng, TH Mosley, AB Newman, CH Newton-Cheh, DN Paltoo, GJ Papanicolaou, N Patterson, WS Post, BM Psaty, AN Qasim, L Qu, DJ Rader, S Redline, MP Reilly, AP Reiner, SS Rich, JI Rotter, Y Liu, P Shrader, DS Siscovick, WH Tang, HA Taylor, RP Tracy, RS Vasan, KM Waters, R Wilks, JG Wilson, RR Fabsitz, SB Gabriel, S Kathiresan, E Boerwinkle

Publication Date: 2011-02-10

Variant appearance in text: rs12654264

PubMed Link: 21347282

Variant Present in the following documents:

• pgen.1001300.s016.doc
• pgen.1001300.s017.doc

View BVdb publication page

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Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology.

Plos Genetics

EJ Rossin, K Lage, S Raychaudhuri, RJ Xavier, D Tatar, Y Benita, , C Cotsapas, MJ Daly

Publication Date: 2011-01-13

Variant appearance in text: rs12654264

PubMed Link: 21249183

Variant Present in the following documents:

• pgen.1001273.s011.xls
• pgen.1001273.s012.xls

View BVdb publication page

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Effects of genetic variants on lipid parameters and dyslipidemia in a Chinese population.

Journal Of Lipid Research

Y Liu, D Zhou, Z Zhang, Y Song, D Zhang, T Zhao, Z Chen, Y Sun, D Zhang, Y Yang, Q Xing, X Zhao, H Xu, L He

Publication Date: 2011-02

Variant appearance in text: rs12654264

PubMed Link: 21149302

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic variants and their interactions in the prediction of increased pre-clinical carotid atherosclerosis: the cardiovascular risk in young Finns study.

Plos Genetics

S Okser, T Lehtimäki, LL Elo, N Mononen, N Peltonen, M Kähönen, M Juonala, YM Fan, JA Hernesniemi, T Laitinen, LP Lyytikäinen, R Rontu, C Eklund, N Hutri-Kähönen, L Taittonen, M Hurme, JS Viikari, OT Raitakari, T Aittokallio

Publication Date: 2010-09-30

Variant appearance in text: rs12654264

PubMed Link: 20941391

Variant Present in the following documents:

• pgen.1001146.s004.xls
• pgen.1001146.s005.xls

View BVdb publication page

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Dysregulation of the mevalonate pathway promotes transformation.

Proceedings Of The National Academy Of Sciences Of The United States Of America

JW Clendening, A Pandyra, PC Boutros, S El Ghamrasni, F Khosravi, GA Trentin, A Martirosyan, A Hakem, R Hakem, I Jurisica, LZ Penn

Publication Date: 2010-08-24

Variant appearance in text: rs12654264

PubMed Link: 20696928

Variant Present in the following documents:

• Main text

View BVdb publication page

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Joint effects of common genetic variants from multiple genes and pathways on the risk of premature coronary artery disease.

American Heart Journal

JL Anderson, BD Horne, NJ Camp, JB Muhlestein, PN Hopkins, LA Cannon-Albright, CP Mower, JJ Park, JL Clarke, ZP Nicholas, JT McKinney, JF Carlquist

Publication Date: 2010-08

Variant appearance in text: rs12654264

PubMed Link: 20691829

Variant Present in the following documents:

• NIHMS209707-supplement-1.doc

View BVdb publication page

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Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.

Plos One

T Zeller, P Wild, S Szymczak, M Rotival, A Schillert, R Castagne, S Maouche, M Germain, K Lackner, H Rossmann, M Eleftheriadis, CR Sinning, RB Schnabel, E Lubos, D Mennerich, W Rust, C Perret, C Proust, V Nicaud, J Loscalzo, N Hübner, D Tregouet, T Münzel, A Ziegler, L Tiret, S Blankenberg, F Cambien

Publication Date: 2010-05-18

Variant appearance in text: rs12654264

PubMed Link: 20502693

Variant Present in the following documents:

• Main text

View BVdb publication page

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PharmGKB: very important pharmacogene--HMGCR.

Pharmacogenetics And Genomics

MW Medina, K Sangkuhl, TE Klein, RB Altman

Publication Date: 2011-02

Variant appearance in text: rs12654264

PubMed Link: 20084049

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association of blood lipids with common DNA sequence variants at 19 genetic loci in the multiethnic United States National Health and Nutrition Examination Survey III.

Circulation. Cardiovascular Genetics

ME Keebler, CL Sanders, A Surti, C Guiducci, NP Burtt, S Kathiresan

Publication Date: 2009-06

Variant appearance in text: rs12654264

PubMed Link: 20031591

Variant Present in the following documents:

• Main text

View BVdb publication page

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Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.

Lipids In Health And Disease

J Ronald, R Rajagopalan, JE Ranchalis, JK Marshall, TS Hatsukami, PJ Heagerty, GP Jarvik

Publication Date: 2009-12-01

Variant appearance in text: rs12654264

PubMed Link: 19951432

Variant Present in the following documents:

• Main text

View BVdb publication page

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Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

American Journal Of Human Genetics

PJ Talmud, F Drenos, S Shah, T Shah, J Palmen, C Verzilli, TR Gaunt, J Pallas, R Lovering, K Li, JP Casas, R Sofat, M Kumari, S Rodriguez, T Johnson, SJ Newhouse, A Dominiczak, NJ Samani, M Caulfield, P Sever, A Stanton, DC Shields, S Padmanabhan, O Melander, C Hastie, C Delles, S Ebrahim, MG Marmot, GD Smith, DA Lawlor, PB Munroe, IN Day, M Kivimaki, J Whittaker, SE Humphries, AD Hingorani, , ,

Publication Date: 2009-11

Variant appearance in text: rs12654264

PubMed Link: 19913121

Variant Present in the following documents:

• mmc1.pdf
• mmc2.xls

View BVdb publication page

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A gene score of nine LDL and HDL regulating genes is associated with fluvastatin-induced cholesterol changes in women.

Journal Of Lipid Research

V Hamrefors, M Orho-Melander, RM Krauss, B Hedblad, P Almgren, G Berglund, O Melander

Publication Date: 2010-03

Variant appearance in text: rs12654264

PubMed Link: 19773416

Variant Present in the following documents:

• Main text

View BVdb publication page

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Ion mobility analysis of lipoprotein subfractions identifies three independent axes of cardiovascular risk.

Arteriosclerosis, Thrombosis, And Vascular Biology

K Musunuru, M Orho-Melander, MP Caulfield, S Li, WA Salameh, RE Reitz, G Berglund, B Hedblad, G Engström, PT Williams, S Kathiresan, O Melander, RM Krauss

Publication Date: 2009-11

Variant appearance in text: rs12654264

PubMed Link: 19729614

Variant Present in the following documents:

• NIHMS149318-supplement-Supp1.pdf

View BVdb publication page

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TagSNP transferability and relative loss of variability prediction from HapMap to an admixed population.

Journal Of Biomedical Science

TC Lins, BS Abreu, RW Pereira

Publication Date: 2009-08-14

Variant appearance in text: rs12654264

PubMed Link: 19682379

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.

Plos Genetics

S Raychaudhuri, RM Plenge, EJ Rossin, AC Ng, , SM Purcell, P Sklar, EM Scolnick, RJ Xavier, D Altshuler, MJ Daly

Publication Date: 2009-06

Variant appearance in text: rs12654264

PubMed Link: 19557189

Variant Present in the following documents:

• pgen.1000534.s003.doc

View BVdb publication page

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The HMG-CoA reductase gene and lipid and lipoprotein levels: the multi-ethnic study of atherosclerosis.

Lipids

YC Chen, YD Chen, X Li, W Post, D Herrington, JF Polak, JI Rotter, KD Taylor

Publication Date: 2009-08

Variant appearance in text: rs12654264

PubMed Link: 19554360

Variant Present in the following documents:

• Main text

View BVdb publication page

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Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.

European Heart Journal

A Murray, C Cluett, S Bandinelli, AM Corsi, L Ferrucci, J Guralnik, A Singleton, T Frayling, D Melzer

Publication Date: 2009-07

Variant appearance in text: rs12654264

PubMed Link: 19435741

Variant Present in the following documents:

• Main text

View BVdb publication page

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Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample.

Journal Of Lipid Research

MB Lanktree, SS Anand, S Yusuf, RA Hegele,

Publication Date: 2009-07

Variant appearance in text: rs12654264

PubMed Link: 19299407

Variant Present in the following documents:

• Main text

View BVdb publication page

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Alternative transcript annotations:

Transcript	cDNA	Protein	Consequence	Exon	Intron
ENST00000287936.4	c.1368+1176A>T	-	intron_variant	-	11/19
ENST00000343975.5	c.1368+1176A>T	-	intron_variant	-	11/18
ENST00000511206.1	c.1368+1176A>T	-	intron_variant	-	11/19
NM_000859.3	c.1368+1176A>T	-	intron_variant	-	11/19
NM_001130996.1	c.1368+1176A>T	-	intron_variant	-	11/18
NM_001364187.1	c.1368+1176A>T	-	intron_variant	-	11/19