Whole-genome sequence-based analysis of thyroid function.
Nature Communications
Taylor, Peter N PN; Porcu, Eleonora E; Chew, Shelby S; Campbell, Purdey J PJ; Traglia, Michela M; Brown, Suzanne J SJ; Mullin, Benjamin H BH; Shihab, Hashem A HA; Min, Josine J; Walter, Klaudia K; Memari, Yasin Y; Huang, Jie J; Barnes, Michael R MR; Beilby, John P JP; Charoen, Pimphen P; Danecek, Petr P; Dudbridge, Frank F; Forgetta, Vincenzo V; Greenwood, Celia C; Grundberg, Elin E; Johnson, Andrew D AD; Hui, Jennie J; Lim, Ee M EM; McCarthy, Shane S; Muddyman, Dawn D; Panicker, Vijay V; Perry, John R B JR; Bell, Jordana T JT; Yuan, Wei W; Relton, Caroline C; Gaunt, Tom T; Schlessinger, David D; Abecasis, Goncalo G; Cucca, Francesco F; Surdulescu, Gabriela L GL; Woltersdorf, Wolfram W; Zeggini, Eleftheria E; Zheng, Hou-Feng HF; Toniolo, Daniela D; Dayan, Colin M CM; Naitza, Silvia S; Walsh, John P JP; Spector, Tim T; Davey Smith, George G; Durbin, Richard R; Richards, J Brent JB; Sanna, Serena S; Soranzo, Nicole N; Timpson, Nicholas J NJ; Wilson, Scott G SG; ,
Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network.
Plos One
Malinowski, Jennifer R JR; Denny, Joshua C JC; Bielinski, Suzette J SJ; Basford, Melissa A MA; Bradford, Yuki Y; Peissig, Peggy L PL; Carrell, David D; Crosslin, David R DR; Pathak, Jyotishman J; Rasmussen, Luke L; Pacheco, Jennifer J; Kho, Abel A; Newton, Katherine M KM; Li, Rongling R; Kullo, Iftikhar J IJ; Chute, Christopher G CG; Chisholm, Rex L RL; Jarvik, Gail P GP; Larson, Eric B EB; McCarty, Catherine A CA; Masys, Daniel R DR; Roden, Dan M DM; de Andrade, Mariza M; Ritchie, Marylyn D MD; Crawford, Dana C DC
A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.
Plos Genetics
Porcu, Eleonora E; Medici, Marco M; Pistis, Giorgio G; Volpato, Claudia B CB; Wilson, Scott G SG; Cappola, Anne R AR; Bos, Steffan D SD; Deelen, Joris J; den Heijer, Martin M; Freathy, Rachel M RM; Lahti, Jari J; Liu, Chunyu C; Lopez, Lorna M LM; Nolte, Ilja M IM; O'Connell, Jeffrey R JR; Tanaka, Toshiko T; Trompet, Stella S; Arnold, Alice A; Bandinelli, Stefania S; Beekman, Marian M; Böhringer, Stefan S; Brown, Suzanne J SJ; Buckley, Brendan M BM; Camaschella, Clara C; de Craen, Anton J M AJ; Davies, Gail G; de Visser, Marieke C H MC; Ford, Ian I; Forsen, Tom T; Frayling, Timothy M TM; Fugazzola, Laura L; Gögele, Martin M; Hattersley, Andrew T AT; Hermus, Ad R AR; Hofman, Albert A; Houwing-Duistermaat, Jeanine J JJ; Jensen, Richard A RA; Kajantie, Eero E; Kloppenburg, Margreet M; Lim, Ee M EM; Masciullo, Corrado C; Mariotti, Stefano S; Minelli, Cosetta C; Mitchell, Braxton D BD; Nagaraja, Ramaiah R; Netea-Maier, Romana T RT; Palotie, Aarno A; Persani, Luca L; Piras, Maria G MG; Psaty, Bruce M BM; Räikkönen, Katri K; Richards, J Brent JB; Rivadeneira, Fernando F; Sala, Cinzia C; Sabra, Mona M MM; Sattar, Naveed N; Shields, Beverley M BM; Soranzo, Nicole N; Starr, John M JM; Stott, David J DJ; Sweep, Fred C G J FC; Usala, Gianluca G; van der Klauw, Melanie M MM; van Heemst, Diana D; van Mullem, Alies A; Vermeulen, Sita H SH; Visser, W Edward WE; Walsh, John P JP; Westendorp, Rudi G J RG; Widen, Elisabeth E; Zhai, Guangju G; Cucca, Francesco F; Deary, Ian J IJ; Eriksson, Johan G JG; Ferrucci, Luigi L; Fox, Caroline S CS; Jukema, J Wouter JW; Kiemeney, Lambertus A LA; Pramstaller, Peter P PP; Schlessinger, David D; Shuldiner, Alan R AR; Slagboom, Eline P EP; Uitterlinden, André G AG; Vaidya, Bijay B; Visser, Theo J TJ; Wolffenbuttel, Bruce H R BH; Meulenbelt, Ingrid I; Rotter, Jerome I JI; Spector, Tim D TD; Hicks, Andrew A AA; Toniolo, Daniela D; Sanna, Serena S; Peeters, Robin P RP; Naitza, Silvia S
A meta-analysis of the associations between common variation in the PDE8B gene and thyroid hormone parameters, including assessment of longitudinal stability of associations over time and effect of thyroid hormone replacement.
European Journal Of Endocrinology
Taylor, Peter N PN; Panicker, Vijay V; Sayers, Adrian A; Shields, Beverley B; Iqbal, Ahmed A; Bremner, Alexandra P AP; Beilby, John P JP; Leedman, Peter J PJ; Hattersley, Andrew T AT; Vaidya, Bijay B; Frayling, Timothy T; Evans, Jonathan J; Tobias, Jonathan H JH; Timpson, Nicholas J NJ; Walsh, John P JP; Dayan, Colin M CM
A locus on chromosome 1p36 is associated with thyrotropin and thyroid function as identified by genome-wide association study.
American Journal Of Human Genetics
Panicker, Vijay V; Wilson, Scott G SG; Walsh, John P JP; Richards, J Brent JB; Brown, Suzanne J SJ; Beilby, John P JP; Bremner, Alexandra P AP; Surdulescu, Gabriela L GL; Qweitin, Emad E; Gillham-Nasenya, Irina I; Soranzo, Nicole N; Lim, Ee M EM; Fletcher, Stephen J SJ; Spector, Tim D TD
Haplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels.
Thyroid : Official Journal Of The American Thyroid Association
Horvath, Anelia A; Faucz, Fabio F; Finkielstain, Gabriela P GP; Nikita, Maria Eleni ME; Rothenbuhler, Anya A; Almeida, Madson M; Mericq, Veronica V; Stratakis, Constantine A CA
Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
Plos Genetics
Lowe, Jennifer K JK; Maller, Julian B JB; Pe'er, Itsik I; Neale, Benjamin M BM; Salit, Jacqueline J; Kenny, Eimear E EE; Shea, Jessica L JL; Burkhardt, Ralph R; Smith, J Gustav JG; Ji, Weizhen W; Noel, Martha M; Foo, Jia Nee JN; Blundell, Maude L ML; Skilling, Vita V; Garcia, Laura L; Sullivan, Marcia L ML; Lee, Heather E HE; Labek, Anna A; Ferdowsian, Hope H; Auerbach, Steven B SB; Lifton, Richard P RP; Newton-Cheh, Christopher C; Breslow, Jan L JL; Stoffel, Markus M; Daly, Mark J MJ; Altshuler, David M DM; Friedman, Jeffrey M JM