Publications:

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Pharmacogenomics of Methotrexate Pathway in Rheumatoid Arthritis Patients: Approach toward Personalized Medicine.

Diagnostics (Basel, Switzerland)

Abdallah, Hoda Y HY; Ibrahim, Maha E ME; Abd El-Fadeal, Noha M NM; Ali, Dina A DA; Elsehrawy, Gehad G GG; Badr, Rasha E RE; Hassoba, Howayda M HM

Publication Date: 2022-06-27

Variant appearance in text: rs10072026

PubMed Link: 35885466

Variant Present in the following documents:

• Main text
• diagnostics-12-01560.pdf

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Pharmacogenetic aspects of methotrexate in a cohort of Colombian patients with rheumatoid arthritis.

Biomedical Reports

Londono, John J; Saldarriaga, Eugenia-Lucia EL; Rueda, Juan C JC; Giraldo-Bustos, Rodrigo R; Angarita, Jose-Ignacio JI; Restrepo, Luisa L; Ballesteros-Muñoz, Jesus J; González, Camilo C; Ospina, Maria J MJ; Arias-Correal, Sofia S; Reyes-Martinez, Viviana V; Bernalmacias, Santiago S; Villota-Eraso, Catalina C; Santos-Moreno, Pedro P; Martinez-Rodriguez, Nancy N; Santos, Ana M AM

Publication Date: 2020-10

Variant appearance in text: rs10072026

PubMed Link: 32793348

Variant Present in the following documents:

• Main text

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Are gene polymorphisms related to adverse events of methotrexate in patients with rheumatoid arthritis? A retrospective cohort study based on an updated meta-analysis.

Therapeutic Advances In Chronic Disease

Huang, Jing J; Fan, Huizhen H; Qiu, Qi Q; Liu, Kunpeng K; Lv, Shuang S; Li, Jiang J; Yang, Hui H; Shu, Xiaoming X; Xu, Yuan Y; Lu, Xiangchen X; Lu, Cheng C; Zhang, Yunnan Y; Xiao, Cheng C

Publication Date: 2020

Variant appearance in text: rs10072026

PubMed Link: 32426102

Variant Present in the following documents:

• Additional_file_1.pdf

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Effects of various genetic polymorphisms on thiopurine treatment-associated outcomes for Korean patients with Crohn's disease.

British Journal Of Clinical Pharmacology

Choi, Rihwa R; Lee, Mi-Na MN; Kim, Kyunga K; Baek, Sun-Young SY; Kim, Tae Jun TJ; Hong, Sung Noh SN; Kim, Young-Ho YH; Lee, Soo-Youn SY

Publication Date: 2020-11

Variant appearance in text: rs10072026

PubMed Link: 32372428

Variant Present in the following documents:

• Main text

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Methotrexate an Old Drug with New Tricks.

International Journal Of Molecular Sciences

Bedoui, Yosra Y; Guillot, Xavier X; Sélambarom, Jimmy J; Guiraud, Pascale P; Giry, Claude C; Jaffar-Bandjee, Marie Christine MC; Ralandison, Stéphane S; Gasque, Philippe P

Publication Date: 2019-10-10

Variant appearance in text: rs10072026

PubMed Link: 31658782

Variant Present in the following documents:

• Main text
• ijms-20-05023.pdf

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Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.

Scientific Reports

Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA

Publication Date: 2019-10-09

Variant appearance in text: rs10072026

PubMed Link: 31597922

Variant Present in the following documents:

• 41598_2019_50891_MOESM5_ESM.xlsx, sheet 1
• 41598_2019_50891_MOESM4_ESM.xlsx, sheet 1

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Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.

Cell Death & Disease

Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D

Publication Date: 2019-02-27

Variant appearance in text: DHFR: 242+68A>G; rs10072026

PubMed Link: 30814510

Variant Present in the following documents:

• 41419_2019_1453_MOESM27_ESM.xlsx, sheet 2

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Replication study of polymorphisms associated with response to methotrexate in patients with rheumatoid arthritis.

Scientific Reports

López-Rodríguez, Rosario R; Ferreiro-Iglesias, Aida A; Lima, Aurea A; Bernardes, Miguel M; Pawlik, Andrzej A; Paradowska-Gorycka, Agnieszka A; Świerkot, Jerzy J; Slezak, Ryszard R; Dolžan, Vita V; González-Álvaro, Isidoro I; Narváez, Javier J; Cáliz, Rafael R; Pérez-Pampín, Eva E; Mera-Varela, Antonio A; Vidal-Bralo, Laura L; Acuña Ochoa, José Gorgonio JG; Conde, Carmen C; Gómez-Reino, Juan J JJ; González, Antonio A

Publication Date: 2018-05-09

Variant appearance in text: rs10072026

PubMed Link: 29743634

Variant Present in the following documents:

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Polymorphisms and pharmacogenomics for the toxicity of methotrexate monotherapy in patients with rheumatoid arthritis: A systematic review and meta-analysis.

Medicine

Qiu, Qi Q; Huang, Jing J; Lin, Yang Y; Shu, Xiaoming X; Fan, Huizheng H; Tu, Zhihua Z; Zhou, Youwen Y; Xiao, Cheng C

Publication Date: 2017-03

Variant appearance in text: rs10072026

PubMed Link: 28296761

Variant Present in the following documents:

• medi-96-e6337.pdf

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Gene variants in the folate-mediated one-carbon metabolism (FOCM) pathway as risk factors for conotruncal heart defects.

American Journal Of Medical Genetics. Part A

Zhu, Huiping H; Yang, Wei W; Lu, Wei W; Etheredge, Analee J AJ; Lammer, Edward J EJ; Finnell, Richard H RH; Carmichael, Suzan L SL; Shaw, Gary M GM

Publication Date: 2012-05

Variant appearance in text: rs10072026

PubMed Link: 22495907

Variant Present in the following documents:

• Main text

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Genetic polymorphisms in key methotrexate pathway genes are associated with response to treatment in rheumatoid arthritis patients.

The Pharmacogenomics Journal

Owen, S A SA; Hider, S L SL; Martin, P P; Bruce, I N IN; Barton, A A; Thomson, W W

Publication Date: 2013-06

Variant appearance in text: rs10072026

PubMed Link: 22450926

Variant Present in the following documents:

• Main text
• ukmss-41103.pdf

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A genetic signature of spina bifida risk from pathway-informed comprehensive gene-variant analysis.

Plos One

Marini, Nicholas J NJ; Hoffmann, Thomas J TJ; Lammer, Edward J EJ; Hardin, Jill J; Lazaruk, Katherine K; Stein, Jason B JB; Gilbert, Dennis A DA; Wright, Crystal C; Lipzen, Anna A; Pennacchio, Len A LA; Carmichael, Suzan L SL; Witte, John S JS; Shaw, Gary M GM; Rine, Jasper J

Publication Date: 2011

Variant appearance in text: rs10072026

PubMed Link: 22140583

Variant Present in the following documents:

• pone.0028408.s004.xls, sheet 1

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Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case-control study.

Cancer Causes & Control : Ccc

Levine, A Joan AJ; Lee, Won W; Figueiredo, Jane C JC; Conti, David V DV; Vandenberg, David J DJ; Davis, Brian D BD; Edlund, Christopher K CK; Henning, Susanne M SM; Heber, David D; Stern, Mariana C MC; Haile, Robert W RW

Publication Date: 2011-04

Variant appearance in text: rs10072026

PubMed Link: 21274745

Variant Present in the following documents:

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