Publications:

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Characteristics of circulating small noncoding RNAs in plasma and serum during human aging.

Aging Medicine (Milton (N.S.W))

Xiao, Ping P; Shi, Zhangyue Z; Liu, Chenang C; Hagen, Darren E DE

Publication Date: 2023-03

Variant appearance in text: rs12206094

PubMed Link: 36911092

Variant Present in the following documents:

• AGM2-6-35-s002.xlsx, sheet 3

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Genetic scores for predicting longevity in the Croatian oldest-old population.

Plos One

Šetinc, Maja M; Celinšćak, Željka Ž; Bočkor, Luka L; Ćorić, Tanja T; Kolarić, Branko B; Stojanović Marković, Anita A; Zajc Petranović, Matea M; Peričić Salihović, Marijana M; Smolej Narančić, Nina N; Škarić-Jurić, Tatjana T

Publication Date: 2023

Variant appearance in text: rs12206094

PubMed Link: 36735720

Variant Present in the following documents:

• Main text
• pone.0279971.pdf

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Current Trends and Approaches to the Search for Genetic Determinants of Aging and Longevity.

Russian Journal Of Genetics

Kunizheva, S S SS; Volobaev, V P VP; Plotnikova, M Yu MY; Kupriyanova, D A DA; Kuznetsova, I L IL; Tyazhelova, T V TV; Rogaev, E I EI

Publication Date: 2022

Variant appearance in text: rs12206094

PubMed Link: 36590179

Variant Present in the following documents:

• Main text
• 11177_2022_Article_1690.pdf

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The Role of Genetic Variants in the Susceptibility of Noise-Induced Hearing Loss.

Frontiers In Cellular Neuroscience

Chen, Xue-Min XM; Xue, Xin-Miao XM; Yu, Ning N; Guo, Wei-Wei WW; Yuan, Shuo-Long SL; Jiang, Qing-Qing QQ; Yang, Shi-Ming SM

Publication Date: 2022

Variant appearance in text: rs12206094

PubMed Link: 35903368

Variant Present in the following documents:

• Main text
• fncel-16-946206.pdf

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Association of FOXO3 Blood DNA Methylation with Cancer Risk, Cancer Survival, and Mortality.

Cells

Yu, Chenglong C; Hodge, Allison M AM; Wong, Ee Ming EM; Joo, Jihoon Eric JE; Makalic, Enes E; Schmidt, Daniel D; Buchanan, Daniel D DD; Hopper, John L JL; Giles, Graham G GG; Southey, Melissa C MC; Dugué, Pierre-Antoine PA

Publication Date: 2021-12-01

Variant appearance in text: rs12206094

PubMed Link: 34943892

Variant Present in the following documents:

• Main text
• cells-10-03384.pdf

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Association of FOXO3 Blood DNA Methylation with Cancer Risk, Cancer Survival, and Mortality.

Cells

Yu, Chenglong C; Hodge, Allison M AM; Wong, Ee Ming EM; Joo, Jihoon Eric JE; Makalic, Enes E; Schmidt, Daniel D; Buchanan, Daniel D DD; Hopper, John L JL; Giles, Graham G GG; Southey, Melissa C MC; Dugué, Pierre-Antoine PA

Publication Date: 2021-12-01

Variant appearance in text: rs12206094

PubMed Link: 34943892

Variant Present in the following documents:

• Main text
• cells-10-03384.pdf

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Role of FoxO transcription factors in aging and age-related metabolic and neurodegenerative diseases.

Cell & Bioscience

Du, Shuqi S; Zheng, Hui H

Publication Date: 2021-11-02

Variant appearance in text: rs12206094

PubMed Link: 34727995

Variant Present in the following documents:

• Main text
• 13578_2021_Article_700.pdf

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Metformin Attenuates ROS via FOXO3 Activation in Immune Cells.

Frontiers In Immunology

Hartwig, Jelka J; Loebel, Madlen M; Steiner, Sophie S; Bauer, Sandra S; Karadeniz, Zehra Z; Roeger, Carsten C; Skurk, Carsten C; Scheibenbogen, Carmen C; Sotzny, Franziska F

Publication Date: 2021

Variant appearance in text: rs12206094

PubMed Link: 33953705

Variant Present in the following documents:

• Main text

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Associations of Adiposity, Circulating Protein Biomarkers, and Risk of Major Vascular Diseases.

Jama Cardiology

Pang, Yuanjie Y; Kartsonaki, Christiana C; Lv, Jun J; Fairhurst-Hunter, Zammy Z; Millwood, Iona Y IY; Yu, Canqing C; Guo, Yu Y; Chen, Yiping Y; Bian, Zheng Z; Yang, Ling L; Chen, Junshi J; Clarke, Robert R; Walters, Robin G RG; Holmes, Michael V MV; Li, Liming L; Chen, Zhengming Z

Publication Date: 2021-03-01

Variant appearance in text: rs12206094

PubMed Link: 33263724

Variant Present in the following documents:

• jamacardiol-e206041-s001.pdf

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DNA methylation QTL analysis identifies new regulators of human longevity.

Human Molecular Genetics

Szymczak, Silke S; Dose, Janina J; Torres, Guillermo G GG; Heinsen, Femke-Anouska FA; Venkatesh, Geetha G; Datlinger, Paul P; Nygaard, Marianne M; Mengel-From, Jonas J; Flachsbart, Friederike F; Klapper, Wolfram W; Christensen, Kaare K; Lieb, Wolfgang W; Schreiber, Stefan S; Häsler, Robert R; Bock, Christoph C; Franke, Andre A; Nebel, Almut A

Publication Date: 2020-05-08

Variant appearance in text: rs12206094

PubMed Link: 32160291

Variant Present in the following documents:

• Main text
• ddaa033.pdf

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A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Nature Communications

Deelen, Joris J; Evans, Daniel S DS; Arking, Dan E DE; Tesi, Niccolò N; Nygaard, Marianne M; Liu, Xiaomin X; Wojczynski, Mary K MK; Biggs, Mary L ML; van der Spek, Ashley A; Atzmon, Gil G; Ware, Erin B EB; Sarnowski, Chloé C; Smith, Albert V AV; Seppälä, Ilkka I; Cordell, Heather J HJ; Dose, Janina J; Amin, Najaf N; Arnold, Alice M AM; Ayers, Kristin L KL; Barzilai, Nir N; Becker, Elizabeth J EJ; Beekman, Marian M; Blanché, Hélène H; Christensen, Kaare K; Christiansen, Lene L; Collerton, Joanna C JC; Cubaynes, Sarah S; Cummings, Steven R SR; Davies, Karen K; Debrabant, Birgit B; Deleuze, Jean-François JF; Duncan, Rachel R; Faul, Jessica D JD; Franceschi, Claudio C; Galan, Pilar P; Gudnason, Vilmundur V; Harris, Tamara B TB; Huisman, Martijn M; Hurme, Mikko A MA; Jagger, Carol C; Jansen, Iris I; Jylhä, Marja M; Kähönen, Mika M; Karasik, David D; Kardia, Sharon L R SLR; Kingston, Andrew A; Kirkwood, Thomas B L TBL; Launer, Lenore J LJ; Lehtimäki, Terho T; Lieb, Wolfgang W; Lyytikäinen, Leo-Pekka LP; Martin-Ruiz, Carmen C; Min, Junxia J; Nebel, Almut A; Newman, Anne B AB; Nie, Chao C; Nohr, Ellen A EA; Orwoll, Eric S ES; Perls, Thomas T TT; Province, Michael A MA; Psaty, Bruce M BM; Raitakari, Olli T OT; Reinders, Marcel J T MJT; Robine, Jean-Marie JM; Rotter, Jerome I JI; Sebastiani, Paola P; Smith, Jennifer J; Sørensen, Thorkild I A TIA; Taylor, Kent D KD; Uitterlinden, André G AG; van der Flier, Wiesje W; van der Lee, Sven J SJ; van Duijn, Cornelia M CM; van Heemst, Diana D; Vaupel, James W JW; Weir, David D; Ye, Kenny K; Zeng, Yi Y; Zheng, Wanlin W; Holstege, Henne H; Kiel, Douglas P DP; Lunetta, Kathryn L KL; Slagboom, P Eline PE; Murabito, Joanne M JM

Publication Date: 2019-08-14

Variant appearance in text: rs12206094

PubMed Link: 31413261

Variant Present in the following documents:

• Main text
• 41467_2019_Article_11558.pdf

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FOXO3 on the Road to Longevity: Lessons From SNPs and Chromatin Hubs.

Computational And Structural Biotechnology Journal

Sanese, Paola P; Forte, Giovanna G; Disciglio, Vittoria V; Grossi, Valentina V; Simone, Cristiano C

Publication Date: 2019

Variant appearance in text: rs12206094

PubMed Link: 31303978

Variant Present in the following documents:

• Main text

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Longevity-Associated Forkhead Box O3 (FOXO3) Single Nucleotide Polymorphisms are Associated with Type 2 Diabetes Mellitus in Chinese Elderly Women.

Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research

Mao, Yu-Qin YQ; Liu, Jin-Feng JF; Han, Bing B; Wang, Li-Shun LS

Publication Date: 2019-04-22

Variant appearance in text: rs12206094

PubMed Link: 31009445

Variant Present in the following documents:

• Main text
• medscimonit-25-2966.pdf

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DNMT1 and DNMT3A haplotypes associated with noise-induced hearing loss in Chinese workers.

Scientific Reports

Ding, Enmin E; Liu, Jing J; Guo, Haoran H; Shen, Huanxi H; Zhang, Hengdong H; Gong, Wei W; Song, Haiyan H; Zhu, Baoli B

Publication Date: 2018-08-15

Variant appearance in text: rs12206094

PubMed Link: 30111769

Variant Present in the following documents:

• Main text
• 41598_2018_Article_29648.pdf

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The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer.

Nucleic Acids Research

Grossi, Valentina V; Forte, Giovanna G; Sanese, Paola P; Peserico, Alessia A; Tezil, Tugsan T; Lepore Signorile, Martina M; Fasano, Candida C; Lovaglio, Rosaura R; Bagnulo, Rosanna R; Loconte, Daria C DC; Susca, Francesco C FC; Resta, Nicoletta N; Simone, Cristiano C

Publication Date: 2018-06-20

Variant appearance in text: rs12206094

PubMed Link: 29733381

Variant Present in the following documents:

• Main text
• gky331.pdf

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Identification and characterization of two functional variants in the human longevity gene FOXO3.

Nature Communications

Flachsbart, Friederike F; Dose, Janina J; Gentschew, Liljana L; Geismann, Claudia C; Caliebe, Amke A; Knecht, Carolin C; Nygaard, Marianne M; Badarinarayan, Nandini N; ElSharawy, Abdou A; May, Sandra S; Luzius, Anne A; Torres, Guillermo G GG; Jentzsch, Marlene M; Forster, Michael M; Häsler, Robert R; Pallauf, Kathrin K; Lieb, Wolfgang W; Derbois, Céline C; Galan, Pilar P; Drichel, Dmitriy D; Arlt, Alexander A; Till, Andreas A; Krause-Kyora, Ben B; Rimbach, Gerald G; Blanché, Hélène H; Deleuze, Jean-François JF; Christiansen, Lene L; Christensen, Kaare K; Nothnagel, Michael M; Rosenstiel, Philip P; Schreiber, Stefan S; Franke, Andre A; Sebens, Susanne S; Nebel, Almut A

Publication Date: 2017-12-12

Variant appearance in text: rs12206094

PubMed Link: 29234056

Variant Present in the following documents:

• Main text
• 41467_2017_2183_MOESM1_ESM.pdf
• 41467_2017_Article_2183.pdf

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Association of genetic variations in FOXO3 gene with susceptibility to noise induced hearing loss in a Chinese population.

Plos One

Guo, Haoran H; Ding, Enmin E; Bai, Ying Y; Zhang, Hengdong H; Shen, Huanxi H; Wang, Jun J; Song, Xianping X; Cai, Wenyan W; Guo, Jiadi J; Zhu, Baoli B

Publication Date: 2017

Variant appearance in text: rs12206094

PubMed Link: 29220389

Variant Present in the following documents:

• Main text

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Effects of FOXO3 Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies.

The Journals Of Gerontology. Series A, Biological Sciences And Medical Sciences

Bae, Harold H; Gurinovich, Anastasia A; Malovini, Alberto A; Atzmon, Gil G; Andersen, Stacy L SL; Villa, Francesco F; Barzilai, Nir N; Puca, Annibale A; Perls, Thomas T TT; Sebastiani, Paola P

Publication Date: 2018-10-08

Variant appearance in text: rs12206094

PubMed Link: 28977569

Variant Present in the following documents:

• Main text

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Genetic Association Analysis of Common Variants in FOXO3 Related to Longevity in a Chinese Population.

Plos One

Lin, Rong R; Zhang, Yunxia Y; Yan, Dongjing D; Liao, Xiaoping X; Wang, Xianshou X; Fu, Yunxin Y; Cai, Wangwei W

Publication Date: 2016

Variant appearance in text: rs12206094

PubMed Link: 27936216

Variant Present in the following documents:

• Main text
• pone.0167918.pdf

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Long live FOXO: unraveling the role of FOXO proteins in aging and longevity.

Aging Cell

Martins, Rute R; Lithgow, Gordon J GJ; Link, Wolfgang W

Publication Date: 2016-04

Variant appearance in text: rs12206094

PubMed Link: 26643314

Variant Present in the following documents:

• Main text
• ACEL-15-196.pdf

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Association study of FOXO3A SNPs and aging phenotypes in Danish oldest-old individuals.

Aging Cell

Soerensen, Mette M; Nygaard, Marianne M; Dato, Serena S; Stevnsner, Tinna T; Bohr, Vilhelm A VA; Christensen, Kaare K; Christiansen, Lene L

Publication Date: 2015-02

Variant appearance in text: rs12206094

PubMed Link: 25470651

Variant Present in the following documents:

• Main text
• acel0014-0060.pdf

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Association between FOXO3A gene polymorphisms and human longevity: a meta-analysis.

Asian Journal Of Andrology

Bao, Ji-Ming JM; Song, Xian-Lu XL; Hong, Ying-Qia YQ; Zhu, Hai-Li HL; Li, Cui C; Zhang, Tao T; Chen, Wei W; Zhao, Shan-Chao SC; Chen, Qing Q

Publication Date: 2014

Variant appearance in text: rs12206094

PubMed Link: 24589462

Variant Present in the following documents:

• AJA-16-446.pdf

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Adjustment for smoking does not alter the FOXO3A association with longevity.

Age (Dordrecht, Netherlands)

Däumer, Carolin C; Flachsbart, Friederike F; Caliebe, Amke A; Schreiber, Stefan S; Nebel, Almut A; Krawczak, Michael M

Publication Date: 2014-04

Variant appearance in text: rs12206094

PubMed Link: 24014251

Variant Present in the following documents:

• Main text

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Exploring the role of genetic variability and lifestyle in oxidative stress response for healthy aging and longevity.

International Journal Of Molecular Sciences

Dato, Serena S; Crocco, Paolina P; D'Aquila, Patrizia P; de Rango, Francesco F; Bellizzi, Dina D; Rose, Giuseppina G; Passarino, Giuseppe G

Publication Date: 2013-08-08

Variant appearance in text: rs12206094

PubMed Link: 23965963

Variant Present in the following documents:

• Main text
• ijms-14-16443.pdf

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A novel permutation test for case-only analysis identifies epistatic effects on human longevity in the FOXO gene family.

Aging Cell

Tan, Qihua Q; Soerensen, Mette M; Kruse, Torben A TA; Christensen, Kaare K; Christiansen, Lene L

Publication Date: 2013-08

Variant appearance in text: rs12206094

PubMed Link: 23607278

Variant Present in the following documents:

• Main text

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Whole genome sequences of a male and female supercentenarian, ages greater than 114 years.

Frontiers In Genetics

Sebastiani, Paola P; Riva, Alberto A; Montano, Monty M; Pham, Phillip P; Torkamani, Ali A; Scherba, Eugene E; Benson, Gary G; Milton, Jacqueline N JN; Baldwin, Clinton T CT; Andersen, Stacy S; Schork, Nicholas J NJ; Steinberg, Martin H MH; Perls, Thomas T TT

Publication Date: 2011

Variant appearance in text: rs12206094

PubMed Link: 22303384

Variant Present in the following documents:

• Main text
• fgene-02-00090.pdf

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Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data.

Aging Cell

Soerensen, Mette M; Dato, Serena S; Christensen, Kaare K; McGue, Matt M; Stevnsner, Tinna T; Bohr, Vilhelm A VA; Christiansen, Lene L

Publication Date: 2010-12

Variant appearance in text: rs12206094

PubMed Link: 20849522

Variant Present in the following documents:

• Main text

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