Rare and low-frequency exonic variants and gene-by-smoking interactions in pulmonary function.
Scientific Reports
Yang, Tianzhong T; Jackson, Victoria E VE; Smith, Albert V AV; Chen, Han H; Bartz, Traci M TM; Sitlani, Colleen M CM; Psaty, Bruce M BM; Gharib, Sina A SA; O'Connor, George T GT; Dupuis, Josée J; Xu, Jiayi J; Lohman, Kurt K; Liu, Yongmei Y; Kritchevsky, Stephen B SB; Cassano, Patricia A PA; Flexeder, Claudia C; Gieger, Christian C; Karrasch, Stefan S; Peters, Annette A; Schulz, Holger H; Harris, Sarah E SE; Starr, John M JM; Deary, Ian J IJ; Manichaikul, Ani A; Oelsner, Elizabeth C EC; Barr, R G RG; Taylor, Kent D KD; Rich, Stephen S SS; Bonten, Tobias N TN; Mook-Kanamori, Dennis O DO; Noordam, Raymond R; Li-Gao, Ruifang R; Jarvelin, Marjo-Riitta MR; Wielscher, Matthias M; Terzikhan, Natalie N; Lahousse, Lies L; Brusselle, Guy G; Weiss, Stefan S; Ewert, Ralf R; Gläser, Sven S; Homuth, Georg G; Shrine, Nick N; Hall, Ian P IP; Tobin, Martin M; London, Stephanie J SJ; Wei, Peng P; Morrison, Alanna C AC
Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects.
American Journal Of Respiratory Cell And Molecular Biology
Busch, Robert R; Hobbs, Brian D BD; Zhou, Jin J; Castaldi, Peter J PJ; McGeachie, Michael J MJ; Hardin, Megan E ME; Hawrylkiewicz, Iwona I; Sliwinski, Pawel P; Yim, Jae-Joon JJ; Kim, Woo Jin WJ; Kim, Deog K DK; Agusti, Alvar A; Make, Barry J BJ; Crapo, James D JD; Calverley, Peter M PM; Donner, Claudio F CF; Lomas, David A DA; Wouters, Emiel F EF; Vestbo, Jørgen J; Tal-Singer, Ruth R; Bakke, Per P; Gulsvik, Amund A; Litonjua, Augusto A AA; Sparrow, David D; Paré, Peter D PD; Levy, Robert D RD; Rennard, Stephen I SI; Beaty, Terri H TH; Hokanson, John J; Silverman, Edwin K EK; Cho, Michael H MH; , ; , ; , ; ,
Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation.
Nature Communications
Soler Artigas, María M; Wain, Louise V LV; Miller, Suzanne S; Kheirallah, Abdul Kader AK; Huffman, Jennifer E JE; Ntalla, Ioanna I; Shrine, Nick N; Obeidat, Ma'en M; Trochet, Holly H; McArdle, Wendy L WL; Alves, Alexessander Couto AC; Hui, Jennie J; Zhao, Jing Hua JH; Joshi, Peter K PK; Teumer, Alexander A; Albrecht, Eva E; Imboden, Medea M; Rawal, Rajesh R; Lopez, Lorna M LM; Marten, Jonathan J; Enroth, Stefan S; Surakka, Ida I; Polasek, Ozren O; Lyytikäinen, Leo-Pekka LP; Granell, Raquel R; Hysi, Pirro G PG; Flexeder, Claudia C; Mahajan, Anubha A; Beilby, John J; Bossé, Yohan Y; Brandsma, Corry-Anke CA; Campbell, Harry H; Gieger, Christian C; Gläser, Sven S; González, Juan R JR; Grallert, Harald H; Hammond, Chris J CJ; Harris, Sarah E SE; Hartikainen, Anna-Liisa AL; Heliövaara, Markku M; Henderson, John J; Hocking, Lynne L; Horikoshi, Momoko M; Hutri-Kähönen, Nina N; Ingelsson, Erik E; Johansson, Åsa Å; Kemp, John P JP; Kolcic, Ivana I; Kumar, Ashish A; Lind, Lars L; Melén, Erik E; Musk, Arthur W AW; Navarro, Pau P; Nickle, David C DC; Padmanabhan, Sandosh S; Raitakari, Olli T OT; Ried, Janina S JS; Ripatti, Samuli S; Schulz, Holger H; Scott, Robert A RA; Sin, Don D DD; Starr, John M JM; , ; Viñuela, Ana A; Völzke, Henry H; Wild, Sarah H SH; Wright, Alan F AF; Zemunik, Tatijana T; Jarvis, Deborah L DL; Spector, Tim D TD; Evans, David M DM; Lehtimäki, Terho T; Vitart, Veronique V; Kähönen, Mika M; Gyllensten, Ulf U; Rudan, Igor I; Deary, Ian J IJ; Karrasch, Stefan S; Probst-Hensch, Nicole M NM; Heinrich, Joachim J; Stubbe, Beate B; Wilson, James F JF; Wareham, Nicholas J NJ; James, Alan L AL; Morris, Andrew P AP; Jarvelin, Marjo-Riitta MR; Hayward, Caroline C; Sayers, Ian I; Strachan, David P DP; Hall, Ian P IP; Tobin, Martin D MD
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Bmc Genetics
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Molecular mechanisms underlying variations in lung function: a systems genetics analysis.
The Lancet. Respiratory Medicine
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A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes.
American Journal Of Respiratory And Critical Care Medicine
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Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease.
Plos One
Sabater-Lleal, Maria M; Mälarstig, Anders A; Folkersen, Lasse L; Soler Artigas, María M; Baldassarre, Damiano D; Kavousi, Maryam M; Almgren, Peter P; Veglia, Fabrizio F; Brusselle, Guy G; Hofman, Albert A; Engström, Gunnar G; Franco, Oscar H OH; Melander, Olle O; Paulsson-Berne, Gabrielle G; Watkins, Hugh H; Eriksson, Per P; Humphries, Steve E SE; Tremoli, Elena E; de Faire, Ulf U; Tobin, Martin D MD; Hamsten, Anders A
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
Nature Genetics
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The association of genome-wide significant spirometric loci with chronic obstructive pulmonary disease susceptibility.
American Journal Of Respiratory Cell And Molecular Biology
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Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.
Nature Genetics
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