Variant ID: 6-151252985-G-A

NM_015440.4(MTHFD1L):c.1257-4955G>A

This variant was identified in 65 publications




Publications:


Influence of SH2B3, MTHFD1L, GGCX, and ITGB3 Gene Polymorphisms on theVariability on Warfarin Dosage Requirements and Susceptibility to CVD in the Jordanian Population.

Journal Of Personalized Medicine
LN Al-Eitan, AY Almasri, RH Khasawneh, MA Alghamdi
Publication Date: 2020-09-09

Variant appearance in text: rs6922269
PubMed Link: 32916786
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of the PSRC1 rs599839 Variant with Coronary Artery Disease in a Mexican Population.

Medicina (Kaunas, Lithuania)
ME Rodríguez-Arellano, J Solares-Tlapechco, P Costa-Urrutia, H Cárdenas-Hernández, M Vallejo-Gómez, J Granados, S Salas-Padilla
Publication Date: 2020-08-26

Variant appearance in text: rs6922269
PubMed Link: 32858814
Variant Present in the following documents:
  • Main text
View BVdb publication page



Validation of a priori candidate Alzheimer's disease SNPs with brain amyloid-beta deposition.

Scientific Reports
M Vacher, T Porter, VL Villemagne, L Milicic, M Peretti, C Fowler, R Martins, S Rainey-Smith, D Ames, CL Masters, CC Rowe, JD Doecke, SM Laws
Publication Date: 2019-11-19

Variant appearance in text: rs6922269
PubMed Link: 31745181
Variant Present in the following documents:
  • 41598_2019_53604_MOESM2_ESM.xlsx
View BVdb publication page



Identifying genetic markers associated with susceptibility to cardiovascular diseases.

Future Science Oa
H Shukla, JL Mason, A Sabyah
Publication Date: 2019-01

Variant appearance in text: rs6922269
PubMed Link: 30652019
Variant Present in the following documents:
  • Main text
View BVdb publication page



Additional value of a combined genetic risk score to standard cardiovascular stratification.

Genetics And Molecular Biology
A Pereira, MI Mendonca, S Borges, AC Sousa, S Freitas, E Henriques, M Rodrigues, AI Freitas, G Guerra, C Freitas, D Pereira, A Brehm, RPD Reis
Publication Date: 2018

Variant appearance in text: rs6922269
PubMed Link: 30571812
Variant Present in the following documents:
  • Main text
View BVdb publication page



A novel genetic marker of decreased inflammation and improved survival after acute myocardial infarction.

Basic Research In Cardiology
ED Coverstone, RG Bach, L Chen, LJ Bierut, AY Li, PA Lenzini, HC O'Neill, JA Spertus, CC Sucharov, JA Stitzel, JD Schilling, S Cresci
Publication Date: 2018-08-10

Variant appearance in text: rs6922269
PubMed Link: 30097758
Variant Present in the following documents:
  • Main text
  • nihms-997604.pdf
View BVdb publication page



Genetic Risk Analysis of Coronary Artery Disease in a Population-based Study in Portugal, Using a Genetic Risk Score of 31 Variants.

Arquivos Brasileiros De Cardiologia
A Pereira, MI Mendonça, S Borges, S Freitas, E Henriques, M Rodrigues, AI Freitas, AC Sousa, A Brehm, RPD Reis
Publication Date: 2018-07

Variant appearance in text: rs6922269
PubMed Link: 29972410
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of TERT polymorphisms and risk of coronary heart disease in a Chinese Han population.

Oncotarget
H Han, J Zhang, J Hou, H Wang, J Zheng, H Wang, Z Zhong, Y Wang, X Wang, B Yang, L Wang, D Quan, J Li
Publication Date: 2017-09-15

Variant appearance in text: rs6922269
PubMed Link: 28978050
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association between PPAP2B gene polymorphisms and coronary heart disease susceptibility in Chinese Han males and females.

Oncotarget
YX Sun, CY Gao, Y Lu, X Fu, JG Jia, YJ Zhao, LD Li, HZ Dui, XY Zhang, ZY Li, L Lei, WF Zhang, YQ Yuan
Publication Date: 2017-02-21

Variant appearance in text: rs6922269
PubMed Link: 28061459
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of rs10757274 and rs2383206 Polymorphisms on 9p21 locus with Coronary Artery Disease in Turkish Population.

Korean Circulation Journal
Ç Yayla, K Okyay, A Yılmaz, A Şahinarslan, AS Yar Sağlam, A Eyiol, HA Bolayır, B Sezenöz, S Menevşe, A Çengel
Publication Date: 2016-09

Variant appearance in text: rs6922269
PubMed Link: 27721851
Variant Present in the following documents:
  • Main text
View BVdb publication page



Coronary Artery Calcification and Rheumatoid Arthritis: Lack of Relationship to Risk Alleles for Coronary Artery Disease in the General Population.

Arthritis & Rheumatology (Hoboken, N.J.)
I Ferraz-Amaro, R Winchester, PK Gregersen, RJ Reynolds, MC Wasko, A Oeser, CP Chung, CM Stein, JT Giles, JM Bathon
Publication Date: 2017-03

Variant appearance in text: rs6922269
PubMed Link: 27696788
Variant Present in the following documents:
  • Main text
  • NIHMS880290-supplement-Supp_TableS1.docx
View BVdb publication page



Implications of Personal Genomic Testing for Health Behaviors: The Case of Smoking.

Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco
E Olfson, S Hartz, DA Carere, RC Green, JS Roberts, LJ Bierut,
Publication Date: 2016-12

Variant appearance in text: rs6922269
PubMed Link: 27613923
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide association analysis and replication of coronary artery disease in South Korea suggests a causal variant common to diverse populations.

Heart Asia
EY Cho, Y Jang, ES Shin, HY Jang, YK Yoo, S Kim, JH Jang, JY Lee, MH Yun, MY Park, JS Chae, JW Lim, DJ Shin, S Park, JH Lee, BG Han, KH Rae, LR Cardon, AP Morris, JE Lee, GM Clarke
Publication Date: 2010

Variant appearance in text: rs6922269
PubMed Link: 27325954
Variant Present in the following documents:
  • Main text
View BVdb publication page



Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.

Data In Brief
JD Vargas, A Manichaikul, XQ Wang, SS Rich, JI Rotter, WS Post, JF Polak, MJ Budoff, DA Bluemke
Publication Date: 2016-06

Variant appearance in text: rs6922269
PubMed Link: 26958643
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma.

Nature Communications
DC Johnson, N Weinhold, JS Mitchell, B Chen, M Kaiser, DB Begum, J Hillengass, U Bertsch, WA Gregory, D Cairns, GH Jackson, A Försti, J Nickel, P Hoffmann, MM Nöethen, OW Stephens, B Barlogie, FE Davis, K Hemminki, H Goldschmidt, RS Houlston, GJ Morgan
Publication Date: 2016-01-08

Variant appearance in text: rs6922269
PubMed Link: 26743840
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic Variants on Chromosome 1p13.3 Are Associated with Non-ST Elevation Myocardial Infarction and the Expression of DRAM2 in the Finnish Population.

Plos One
PP Salo, S Vaara, J Kettunen, M Pirinen, AP Sarin, H Huikuri, PJ Karhunen, M Eskola, K Nikus, ML Lokki, S Ripatti, AS Havulinna, V Salomaa, A Palotie, MS Nieminen, J Sinisalo, M Perola
Publication Date: 2015

Variant appearance in text: rs6922269
PubMed Link: 26509668
Variant Present in the following documents:
  • pone.0140576.s001.pdf
View BVdb publication page



Genetic Basis of Common Human Disease: Insight into the Role of Missense SNPs from Genome-Wide Association Studies.

Journal Of Molecular Biology
LR Pal, J Moult
Publication Date: 2015-07-03

Variant appearance in text: rs6922269
PubMed Link: 25937569
Variant Present in the following documents:
  • NIHMS691543-supplement-1.pdf
View BVdb publication page



Burden of disease variants in participants of the Long Life Family Study.

Aging
M Stevenson, H Bae, N Schupf, S Andersen, Q Zhang, T Perls, P Sebastiani
Publication Date: 2015-02

Variant appearance in text: rs6922269
PubMed Link: 25664523
Variant Present in the following documents:
  • aging-07-0123-s001.docx
View BVdb publication page



The impact of coronary artery disease risk loci on ischemic heart failure severity and prognosis: association analysis in the COntrolled ROsuvastatin multiNAtional trial in heart failure (CORONA).

Bmc Medical Genetics
VG Haver, N Verweij, J Kjekshus, JC Fox, H Wedel, J Wikstrand, WH van Gilst, RA de Boer, DJ van Veldhuisen, P van der Harst
Publication Date: 2014-12-21

Variant appearance in text: rs6922269
PubMed Link: 25528061
Variant Present in the following documents:
  • 12881_2014_140_MOESM2_ESM.xlsx
  • 12881_2014_140_MOESM4_ESM.xlsx
  • 12881_2014_140_MOESM5_ESM.xlsx
  • 12881_2014_140_MOESM6_ESM.xlsx
  • 12881_2014_140_MOESM7_ESM.xlsx
  • aaaaaMain text
View BVdb publication page



Evaluation of association between common genetic variants on chromosome 9p21 and coronary artery disease in Turkish population.

Anatolian Journal Of Cardiology
HA Çakmak, B Bayoğlu, E Durmaz, G Can, B Karadağ, M Cengiz, VA Vural, H Yüksel
Publication Date: 2015-03

Variant appearance in text: rs6922269
PubMed Link: 25333979
Variant Present in the following documents:
  • Main text
View BVdb publication page



A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.

European Journal Of Human Genetics : Ejhg
M Hirokawa, H Morita, T Tajima, A Takahashi, K Ashikawa, F Miya, D Shigemizu, K Ozaki, Y Sakata, D Nakatani, S Suna, Y Imai, T Tanaka, T Tsunoda, K Matsuda, T Kadowaki, Y Nakamura, R Nagai, I Komuro, M Kubo
Publication Date: 2015-03

Variant appearance in text: rs6922269
PubMed Link: 24916648
Variant Present in the following documents:
  • ejhg2014110x4.pdf
View BVdb publication page



Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study.

Circulation. Cardiovascular Genetics
JM Kocarnik, SA Pendergrass, CL Carty, JS Pankow, FR Schumacher, I Cheng, P Durda, JL Ambite, E Deelman, NR Cook, S Liu, J Wactawski-Wende, C Hutter, K Brown-Gentry, S Wilson, LG Best, N Pankratz, CP Hong, SA Cole, VS Voruganti, P Bůžkova, NW Jorgensen, NS Jenny, LR Wilkens, CA Haiman, LN Kolonel, A Lacroix, K North, R Jackson, L Le Marchand, LA Hindorff, DC Crawford, M Gross, U Peters
Publication Date: 2014-04

Variant appearance in text: rs6922269
PubMed Link: 24622110
Variant Present in the following documents:
  • NIHMS575195-supplement-000173_-_Supplemental_Material.pdf
View BVdb publication page



Genetic polymorphism rs6922269 in the MTHFD1L gene is associated with survival and baseline active vitamin B12 levels in post-acute coronary syndromes patients.

Plos One
BR Palmer, S Slow, KL Ellis, AP Pilbrow, L Skelton, CM Frampton, SC Palmer, RW Troughton, TG Yandle, RN Doughty, GA Whalley, M Lever, PM George, ST Chambers, C Ellis, AM Richards, VA Cameron
Publication Date: 2014

Variant appearance in text: rs6922269
PubMed Link: 24618918
Variant Present in the following documents:
  • Main text
  • pone.0089029.s001.docx
View BVdb publication page



Genetic analysis of a population heavy drinking phenotype identifies risk variants in whites.

Journal Of Clinical Psychopharmacology
A Hamidovic, RJ Goodloe, TR Young, MA Styn, KJ Mukamal, H Choquet, JL Kasberger, SG Buxbaum, GJ Papanicolaou, W White, K Volcik, B Spring, B Hitsman, D Levy, E Jorgenson
Publication Date: 2013-04

Variant appearance in text: rs6922269
PubMed Link: 23422394
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of cardiovascular and metabolic disease genes with psoriasis.

The Journal Of Investigative Dermatology
Y Lu, H Chen, P Nikamo, H Qi Low, C Helms, M Seielstad, J Liu, AM Bowcock, M Stahle, W Liao
Publication Date: 2013-03

Variant appearance in text: rs6922269
PubMed Link: 23190900
Variant Present in the following documents:
  • NIHMS404713-supplement-01.pdf
View BVdb publication page



Genetic variants associated with myocardial infarction in the PSMA6 gene and Chr9p21 are also associated with ischaemic stroke.

European Journal Of Neurology
MG Heckman, AI Soto-Ortolaza, NN Diehl, S Rayaprolu, TG Brott, ZK Wszolek, JF Meschia, OA Ross
Publication Date: 2013-02

Variant appearance in text: rs6922269
PubMed Link: 22882272
Variant Present in the following documents:
  • Main text
  • NIHMS392973-supplement-supplement_1.pdf
View BVdb publication page



Hypothesis-based analysis of gene-gene interactions and risk of myocardial infarction.

Plos One
G Lucas, C Lluís-Ganella, I Subirana, MD Musameh, JR Gonzalez, CP Nelson, M Sentí, , , SM Schwartz, D Siscovick, CJ O'Donnell, O Melander, V Salomaa, S Purcell, D Altshuler, NJ Samani, S Kathiresan, R Elosua
Publication Date: 2012

Variant appearance in text: rs6922269
PubMed Link: 22876292
Variant Present in the following documents:
  • pone.0041730.s001.pdf
View BVdb publication page



Genetically distinct subsets within ANCA-associated vasculitis.

The New England Journal Of Medicine
PA Lyons, TF Rayner, S Trivedi, JU Holle, RA Watts, DR Jayne, B Baslund, P Brenchley, A Bruchfeld, AN Chaudhry, JW Cohen Tervaert, P Deloukas, C Feighery, WL Gross, L Guillevin, I Gunnarsson, L Harper, Z Hrušková, MA Little, D Martorana, T Neumann, S Ohlsson, S Padmanabhan, CD Pusey, AD Salama, JS Sanders, CO Savage, M Segelmark, CA Stegeman, V Tesař, A Vaglio, S Wieczorek, B Wilde, J Zwerina, AJ Rees, DG Clayton, KG Smith
Publication Date: 2012-07-19

Variant appearance in text: rs6922269
PubMed Link: 22808956
Variant Present in the following documents:
  • NIHMS54600-supplement-supporting_info.pdf
View BVdb publication page



A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies.

Atherosclerosis
A Brautbar, LA Pompeii, A Dehghan, JS Ngwa, V Nambi, SS Virani, F Rivadeneira, AG Uitterlinden, A Hofman, JC Witteman, MJ Pencina, AR Folsom, LA Cupples, CM Ballantyne, E Boerwinkle
Publication Date: 2012-08

Variant appearance in text: rs6922269
PubMed Link: 22789513
Variant Present in the following documents:
  • Main text
View BVdb publication page



Assessment of the value of a genetic risk score in improving the estimation of coronary risk.

Atherosclerosis
C Lluis-Ganella, I Subirana, G Lucas, M Tomás, D Muñoz, M Sentí, E Salas, J Sala, R Ramos, JM Ordovas, J Marrugat, R Elosua
Publication Date: 2012-06

Variant appearance in text: rs6922269
PubMed Link: 22521901
Variant Present in the following documents:
  • NIHMS472525-supplement-01.pdf
View BVdb publication page



Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain.

Neurobiology Of Disease
DG Hernandez, MA Nalls, M Moore, S Chong, A Dillman, D Trabzuni, JR Gibbs, M Ryten, S Arepalli, ME Weale, AB Zonderman, J Troncoso, R O'Brien, R Walker, C Smith, S Bandinelli, BJ Traynor, J Hardy, AB Singleton, MR Cookson
Publication Date: 2012-07

Variant appearance in text: rs6922269
PubMed Link: 22433082
Variant Present in the following documents:
  • mmc1.xls
View BVdb publication page



Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study.

Circulation. Cardiovascular Genetics
CL Carty, P Buzková, M Fornage, N Franceschini, S Cole, G Heiss, LA Hindorff, BV Howard, S Mann, LW Martin, Y Zhang, TC Matise, R Prentice, AP Reiner, C Kooperberg
Publication Date: 2012-04-01

Variant appearance in text: rs6922269
PubMed Link: 22403240
Variant Present in the following documents:
  • NIHMS369440-supplement-01.pdf
View BVdb publication page



Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--a meta-analysis of three independent studies.

Plos One
JA Hernesniemi, I Seppälä, LP Lyytikäinen, N Mononen, N Oksala, N Hutri-Kähönen, M Juonala, L Taittonen, EN Smith, NJ Schork, W Chen, SR Srinivasan, GS Berenson, SS Murray, T Laitinen, A Jula, J Kettunen, S Ripatti, R Laaksonen, J Viikari, M Kähönen, OT Raitakari, T Lehtimäki
Publication Date: 2012

Variant appearance in text: rs6922269
PubMed Link: 22295058
Variant Present in the following documents:
  • Main text
View BVdb publication page



Large scale association analysis identifies three susceptibility loci for coronary artery disease.

Plos One
S Saade, JB Cazier, M Ghassibe-Sabbagh, S Youhanna, DA Badro, Y Kamatani, J Hager, JS Yeretzian, G El-Khazen, M Haber, AK Salloum, B Douaihy, R Othman, N Shasha, S Kabbani, HE Bayeh, E Chammas, M Farrall, D Gauguier, DE Platt, PA Zalloua,
Publication Date: 2011

Variant appearance in text: rs6922269
PubMed Link: 22216278
Variant Present in the following documents:
  • Main text
  • pone.0029427.s002.doc
  • pone.0029427.s003.doc
View BVdb publication page



Folate network genetic variation, plasma homocysteine, and global genomic methylation content: a genetic association study.

Bmc Medical Genetics
SM Wernimont, AG Clark, PJ Stover, MT Wells, AA Litonjua, ST Weiss, JM Gaziano, KL Tucker, A Baccarelli, J Schwartz, V Bollati, PA Cassano
Publication Date: 2011-11-21

Variant appearance in text: rs6922269
PubMed Link: 22103680
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of genetic variants and incident coronary heart disease in multiethnic cohorts: the PAGE study.

Circulation. Cardiovascular Genetics
N Franceschini, C Carty, P Bůzková, AP Reiner, T Garrett, Y Lin, JS Vöckler, LA Hindorff, SA Cole, E Boerwinkle, DY Lin, E Bookman, LG Best, JN Bella, C Eaton, P Greenland, N Jenny, KE North, D Taverna, AM Young, E Deelman, C Kooperberg, B Psaty, G Heiss
Publication Date: 2011-12

Variant appearance in text: rs6922269
PubMed Link: 22042884
Variant Present in the following documents:
  • Main text
  • NIHMS340747-supplement-1.pdf
View BVdb publication page



Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome.

Bmc Medical Genetics
TM Morgan, JA House, S Cresci, P Jones, H Allayee, SL Hazen, Y Patel, RS Patel, DJ Eapen, SP Waddy, AA Quyyumi, ME Kleber, W März, BR Winkelmann, BO Boehm, HM Krumholz, JA Spertus
Publication Date: 2011-09-29

Variant appearance in text: rs6922269
PubMed Link: 21957892
Variant Present in the following documents:
  • Main text
View BVdb publication page



Implications of discoveries from genome-wide association studies in current cardiovascular practice.

World Journal Of Cardiology
P Jeemon, K Pettigrew, C Sainsbury, D Prabhakaran, S Padmanabhan
Publication Date: 2011-07-26

Variant appearance in text: rs6922269
PubMed Link: 21860704
Variant Present in the following documents:
  • Main text
View BVdb publication page



Efficient replication of over 180 genetic associations with self-reported medical data.

Plos One
JY Tung, CB Do, DA Hinds, AK Kiefer, JM Macpherson, AB Chowdry, U Francke, BT Naughton, JL Mountain, A Wojcicki, N Eriksson
Publication Date: 2011

Variant appearance in text: rs6922269
PubMed Link: 21858135
Variant Present in the following documents:
  • pone.0023473.s003.docx
  • pone.0023473.s009.docx
View BVdb publication page



Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration.

European Heart Journal
A Angelakopoulou, T Shah, R Sofat, S Shah, DJ Berry, J Cooper, J Palmen, I Tzoulaki, A Wong, BJ Jefferis, N Maniatis, F Drenos, B Gigante, R Hardy, RC Laxton, K Leander, A Motterle, IA Simpson, L Smeeth, A Thomson, C Verzilli, D Kuh, H Ireland, J Deanfield, M Caulfield, C Wallace, N Samani, PB Munroe, M Lathrop, FG Fowkes, M Marmot, PH Whincup, JC Whittaker, U de Faire, M Kivimaki, M Kumari, E Hypponen, C Power, SE Humphries, PJ Talmud, J Price, RW Morris, S Ye, JP Casas, AD Hingorani
Publication Date: 2012-02

Variant appearance in text: rs6922269
PubMed Link: 21804106
Variant Present in the following documents:
  • Main text
View BVdb publication page



Maps of open chromatin guide the functional follow-up of genome-wide association signals: application to hematological traits.

Plos Genetics
DS Paul, JP Nisbet, TP Yang, S Meacham, A Rendon, K Hautaviita, J Tallila, J White, MR Tijssen, S Sivapalaratnam, H Basart, MD Trip, , , B Göttgens, N Soranzo, WH Ouwehand, P Deloukas
Publication Date: 2011-06

Variant appearance in text: rs6922269
PubMed Link: 21738486
Variant Present in the following documents:
  • pgen.1002139.s016.pdf
View BVdb publication page



Replication of putative susceptibility loci from genome-wide association studies associated with coronary atherosclerosis in Chinese Han population.

Plos One
F Xie, X Chu, H Wu, W Sun, M Shen, L Yang, Y Wang, Y Wang, J Shi, W Huang
Publication Date: 2011

Variant appearance in text: rs6922269
PubMed Link: 21698238
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of SNP rs17465637 on chromosome 1q41 and rs599839 on 1p13.3 with myocardial infarction in an American caucasian population.

Annals Of Human Genetics
AZ Wang, L Li, B Zhang, GQ Shen, QK Wang
Publication Date: 2011-07

Variant appearance in text: rs6922269
PubMed Link: 21463265
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.

Plos Genetics
G Lettre, CD Palmer, T Young, KG Ejebe, H Allayee, EJ Benjamin, F Bennett, DW Bowden, A Chakravarti, A Dreisbach, DN Farlow, AR Folsom, M Fornage, T Forrester, E Fox, CA Haiman, J Hartiala, TB Harris, SL Hazen, SR Heckbert, BE Henderson, JN Hirschhorn, BJ Keating, SB Kritchevsky, E Larkin, M Li, ME Rudock, CA McKenzie, JB Meigs, YA Meng, TH Mosley, AB Newman, CH Newton-Cheh, DN Paltoo, GJ Papanicolaou, N Patterson, WS Post, BM Psaty, AN Qasim, L Qu, DJ Rader, S Redline, MP Reilly, AP Reiner, SS Rich, JI Rotter, Y Liu, P Shrader, DS Siscovick, WH Tang, HA Taylor, RP Tracy, RS Vasan, KM Waters, R Wilks, JG Wilson, RR Fabsitz, SB Gabriel, S Kathiresan, E Boerwinkle
Publication Date: 2011-02-10

Variant appearance in text: rs6922269
PubMed Link: 21347282
Variant Present in the following documents:
  • pgen.1001300.s016.doc
  • pgen.1001300.s017.doc
View BVdb publication page



Genetics of hypertension and cardiovascular disease and their interconnected pathways: lessons from large studies.

Current Hypertension Reports
AT Kraja, SC Hunt, DC Rao, VG Dávila-Román, DK Arnett, MA Province
Publication Date: 2011-02

Variant appearance in text: rs6922269
PubMed Link: 21128019
Variant Present in the following documents:
  • NIHMS265187-supplement-1.pdf
View BVdb publication page



Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus.

Plos One
CG Bell, S Finer, CM Lindgren, GA Wilson, VK Rakyan, AE Teschendorff, P Akan, E Stupka, TA Down, I Prokopenko, IM Morison, J Mill, R Pidsley, , P Deloukas, TM Frayling, AT Hattersley, MI McCarthy, S Beck, GA Hitman
Publication Date: 2010-11-18

Variant appearance in text: rs6922269
PubMed Link: 21124985
Variant Present in the following documents:
  • pone.0014040.s005.xls
View BVdb publication page



Genome-wide association study of coronary artery disease.

International Journal Of Hypertension
N Ogawa, Y Imai, H Morita, R Nagai
Publication Date: 2010-09-21

Variant appearance in text: rs6922269
PubMed Link: 20981302
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic variants and their interactions in the prediction of increased pre-clinical carotid atherosclerosis: the cardiovascular risk in young Finns study.

Plos Genetics
S Okser, T Lehtimäki, LL Elo, N Mononen, N Peltonen, M Kähönen, M Juonala, YM Fan, JA Hernesniemi, T Laitinen, LP Lyytikäinen, R Rontu, C Eklund, N Hutri-Kähönen, L Taittonen, M Hurme, JS Viikari, OT Raitakari, T Aittokallio
Publication Date: 2010-09-30

Variant appearance in text: rs6922269
PubMed Link: 20941391
Variant Present in the following documents:
  • pgen.1001146.s004.xls
  • pgen.1001146.s005.xls
  • pgen.1001146.s007.xls
View BVdb publication page



Improved prediction of cardiovascular disease based on a panel of single nucleotide polymorphisms identified through genome-wide association studies.

Circulation. Cardiovascular Genetics
RW Davies, S Dandona, AF Stewart, L Chen, SG Ellis, WH Tang, SL Hazen, R Roberts, R McPherson, GA Wells
Publication Date: 2010-10

Variant appearance in text: rs6922269
PubMed Link: 20729558
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association between a literature-based genetic risk score and cardiovascular events in women.

Jama
NP Paynter, DI Chasman, G Paré, JE Buring, NR Cook, JP Miletich, PM Ridker
Publication Date: 2010-02-17

Variant appearance in text: rs6922269
PubMed Link: 20159871
Variant Present in the following documents:
  • NIHMS173546-supplement-supplement_1.pdf
View BVdb publication page



Evaluation of population impact of candidate polymorphisms for coronary heart disease in the Framingham Heart Study Offspring Cohort.

Bmc Proceedings
Y Yan, Y Hu, KE North, N Franceschini, D Lin
Publication Date: 2009-12-15

Variant appearance in text: rs6922269
PubMed Link: 20017983
Variant Present in the following documents:
  • Main text
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How many genetic variants remain to be discovered?

Plos One
Y Pawitan, KC Seng, PK Magnusson
Publication Date: 2009-12-02

Variant appearance in text: rs6922269
PubMed Link: 19956539
Variant Present in the following documents:
  • pone.0007969.s001.xls
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Genetics of coronary artery disease: focus on genome-wide association studies.

American Journal Of Translational Research
LM Baudhuin
Publication Date: 2009-03-05

Variant appearance in text: rs6922269
PubMed Link: 19956433
Variant Present in the following documents:
  • Main text
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Genetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities study.

American Journal Of Epidemiology
J Bressler, AR Folsom, DJ Couper, KA Volcik, E Boerwinkle
Publication Date: 2010-01-01

Variant appearance in text: rs6922269
PubMed Link: 19955471
Variant Present in the following documents:
  • Main text
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A common variant in MTHFD1L is associated with neural tube defects and mRNA splicing efficiency.

Human Mutation
A Parle-McDermott, F Pangilinan, KK O'Brien, JL Mills, AM Magee, J Troendle, M Sutton, JM Scott, PN Kirke, AM Molloy, LC Brody
Publication Date: 2009-12

Variant appearance in text: rs6922269
PubMed Link: 19777576
Variant Present in the following documents:
  • Main text
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Genome-wide association studies for atherosclerotic vascular disease and its risk factors.

Circulation. Cardiovascular Genetics
K Ding, IJ Kullo
Publication Date: 2009-02

Variant appearance in text: rs6922269
PubMed Link: 19750184
Variant Present in the following documents:
  • Main text
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Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk.

Human Molecular Genetics
F Drenos, PJ Talmud, JP Casas, L Smeeth, J Palmen, SE Humphries, AD Hingorani
Publication Date: 2009-06-15

Variant appearance in text: rs6922269
PubMed Link: 19336475
Variant Present in the following documents:
  • Main text
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Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.

Nature Genetics
, S Kathiresan, BF Voight, S Purcell, K Musunuru, D Ardissino, PM Mannucci, S Anand, JC Engert, NJ Samani, H Schunkert, J Erdmann, MP Reilly, DJ Rader, T Morgan, JA Spertus, M Stoll, D Girelli, PP McKeown, CC Patterson, DS Siscovick, CJ O'Donnell, R Elosua, L Peltonen, V Salomaa, SM Schwartz, O Melander, D Altshuler, D Ardissino, PA Merlini, C Berzuini, L Bernardinelli, F Peyvandi, M Tubaro, P Celli, M Ferrario, R Fetiveau, N Marziliano, G Casari, M Galli, F Ribichini, M Rossi, F Bernardi, P Zonzin, A Piazza, PM Mannucci, SM Schwartz, DS Siscovick, J Yee, Y Friedlander, R Elosua, J Marrugat, G Lucas, I Subirana, J Sala, R Ramos, S Kathiresan, JB Meigs, G Williams, DM Nathan, CA MacRae, CJ O'Donnell, V Salomaa, AS Havulinna, L Peltonen, O Melander, G Berglund, BF Voight, S Kathiresan, JN Hirschhorn, R Asselta, S Duga, M Spreafico, K Musunuru, MJ Daly, S Purcell, BF Voight, S Purcell, J Nemesh, JM Korn, SA McCarroll, SM Schwartz, J Yee, S Kathiresan, G Lucas, I Subirana, R Elosua, A Surti, C Guiducci, L Gianniny, D Mirel, M Parkin, N Burtt, SB Gabriel, NJ Samani, JR Thompson, PS Braund, BJ Wright, AJ Balmforth, SG Ball, A Hall, , H Schunkert, J Erdmann, P Linsel-Nitschke, W Lieb, A Ziegler, I König, C Hengstenberg, M Fischer, K Stark, A Grosshennig, M Preuss, HE Wichmann, S Schreiber, H Schunkert, NJ Samani, J Erdmann, W Ouwehand, C Hengstenberg, P Deloukas, M Scholz, F Cambien, MP Reilly, M Li, Z Chen, R Wilensky, W Matthai, A Qasim, HH Hakonarson, J Devaney, MS Burnett, AD Pichard, KM Kent, L Satler, JM Lindsay, R Waksman, CW Knouff, DM Waterworth, MC Walker, V Mooser, SE Epstein, DJ Rader, T Scheffold, K Berger, M Stoll, A Huge, D Girelli, N Martinelli, O Olivieri, R Corrocher, T Morgan, JA Spertus, P McKeown, CC Patterson, H Schunkert, E Erdmann, P Linsel-Nitschke, W Lieb, A Ziegler, IR König, C Hengstenberg, M Fischer, K Stark, A Grosshennig, M Preuss, HE Wichmann, S Schreiber, H Hólm, G Thorleifsson, U Thorsteinsdottir, K Stefansson, JC Engert, R Do, C Xie, S Anand, S Kathiresan, D Ardissino, PM Mannucci, D Siscovick, CJ O'Donnell, NJ Samani, O Melander, R Elosua, L Peltonen, V Salomaa, SM Schwartz, D Altshuler
Publication Date: 2009-03

Variant appearance in text: rs6922269
PubMed Link: 19198609
Variant Present in the following documents:
  • Main text
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Large scale association analysis of novel genetic loci for coronary artery disease.

Arteriosclerosis, Thrombosis, And Vascular Biology
, NJ Samani, P Deloukas, J Erdmann, C Hengstenberg, K Kuulasmaa, R McGinnis, H Schunkert, N Soranzo, J Thompson, L Tiret, A Ziegler
Publication Date: 2009-05

Variant appearance in text: rs6922269
PubMed Link: 19164808
Variant Present in the following documents:
  • Main text
  • NIHMS5156-supplement-Supplemental_Materials.pdf
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The impact of newly identified loci on coronary heart disease, stroke and total mortality in the MORGAM prospective cohorts.

Genetic Epidemiology
J Karvanen, K Silander, F Kee, L Tiret, V Salomaa, K Kuulasmaa, PG Wiklund, J Virtamo, O Saarela, C Perret, M Perola, L Peltonen, F Cambien, J Erdmann, NJ Samani, H Schunkert, A Evans,
Publication Date: 2009-04

Variant appearance in text: rs6922269
PubMed Link: 18979498
Variant Present in the following documents:
  • Main text
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Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.

Human Molecular Genetics
KL Mohlke, M Boehnke, GR Abecasis
Publication Date: 2008-10-15

Variant appearance in text: rs6922269
PubMed Link: 18852197
Variant Present in the following documents:
  • Main text
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Association studies of 22 candidate SNPs with late-onset Alzheimer's disease.

American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
JA Figgins, RL Minster, FY Demirci, ST Dekosky, MI Kamboh
Publication Date: 2009-06-05

Variant appearance in text: rs6922269
PubMed Link: 18780302
Variant Present in the following documents:
  • Main text
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Novel genetic variants linked to coronary artery disease by genome-wide association are not associated with carotid artery intima-media thickness or intermediate risk phenotypes.

Atherosclerosis
MS Cunnington, BM Mayosi, DH Hall, PJ Avery, M Farrall, MA Vickers, H Watkins, B Keavney
Publication Date: 2009-03

Variant appearance in text: rs6922269
PubMed Link: 18675980
Variant Present in the following documents:
  • Main text
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Genomewide association analysis of coronary artery disease.

The New England Journal Of Medicine
NJ Samani, J Erdmann, AS Hall, C Hengstenberg, M Mangino, B Mayer, RJ Dixon, T Meitinger, P Braund, HE Wichmann, JH Barrett, IR König, SE Stevens, S Szymczak, DA Tregouet, MM Iles, F Pahlke, H Pollard, W Lieb, F Cambien, M Fischer, W Ouwehand, S Blankenberg, AJ Balmforth, A Baessler, SG Ball, TM Strom, I Braenne, C Gieger, P Deloukas, MD Tobin, A Ziegler, JR Thompson, H Schunkert,
Publication Date: 2007-08-02

Variant appearance in text: rs6922269
PubMed Link: 17634449
Variant Present in the following documents:
  • Main text
  • NIHMS4594-supplement-S1.pdf
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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.

Nature
Publication Date: 2007-06-07

Variant appearance in text: rs6922269
PubMed Link: 17554300
Variant Present in the following documents:
  • Main text
  • NIHMS4894-supplement-S1.pdf
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Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000367321.3 c.1257-4955G>A - intron_variant - 11/27
ENST00000441122.1 c.270-4955G>A - intron_variant - 10/10
NM_001242767.1 c.1260-4955G>A - intron_variant - 11/27
NM_001242768.1 c.1062-4955G>A - intron_variant - 11/27
NM_001350486.1 c.1059-4955G>A - intron_variant - 11/27
NM_001350487.1 c.927-4955G>A - intron_variant - 11/27
NM_001350492.1 c.930-4955G>A - intron_variant - 11/27
NM_001350493.1 c.930-4955G>A - intron_variant - 11/27
NM_015440.4 c.1257-4955G>A - intron_variant - 11/27
NR_146719.1 n.1401-4955G>A - intron_variant,non_coding_transcript_variant - 11/28
NR_146720.1 n.2166-4955G>A - intron_variant,non_coding_transcript_variant - 11/28