Polygenic Models Partially Predict Muscle Size and Strength but Not Low Muscle Mass in Older Women.
Genes
Khanal, Praval P; Morse, Christopher I CI; He, Lingxiao L; Herbert, Adam J AJ; Onambélé-Pearson, Gladys L GL; Degens, Hans H; Thomis, Martine M; Williams, Alun G AG; Stebbings, Georgina K GK
Role of Estrogen and Its Receptors in Adipose Tissue Glucose Metabolism in Pre- and Postmenopausal Women.
The Journal Of Clinical Endocrinology And Metabolism
Ahmed, Fozia F; Kamble, Prasad G PG; Hetty, Susanne S; Fanni, Giovanni G; Vranic, Milica M; Sarsenbayeva, Assel A; Kristófi, Robin R; Almby, Kristina K; Svensson, Maria K MK; Pereira, Maria J MJ; Eriksson, Jan W JW
The Association of Multiple Gene Variants with Ageing Skeletal Muscle Phenotypes in Elderly Women.
Genes
Khanal, Praval P; He, Lingxiao L; Herbert, Adam J AJ; Stebbings, Georgina K GK; Onambele-Pearson, Gladys L GL; Degens, Hans H; Morse, Christopher I CI; Thomis, Martine M; Williams, Alun G AG
Prevalence and association of single nucleotide polymorphisms with sarcopenia in older women depends on definition.
Scientific Reports
Khanal, Praval P; He, Lingxiao L; Stebbings, Georgina G; Onambele-Pearson, Gladys L GL; Degens, Hans H; Williams, Alun A; Thomis, Martine M; Morse, Christopher I CI
A Pilot Genome-Wide Association Study in Postmenopausal Mexican-Mestizo Women Implicates the RMND1/CCDC170 Locus Is Associated with Bone Mineral Density.
International Journal Of Genomics
Villalobos-Comparán, Marisela M; Jiménez-Ortega, Rogelio F RF; Estrada, Karol K; Parra-Torres, Alma Y AY; González-Mercado, Anahí A; Patiño, Nelly N; Castillejos-López, Manuel M; Quiterio, Manuel M; Fernandez-López, Juan Carlos JC; Ibarra, Bertha B; Romero-Hidalgo, Sandra S; Salmerón, Jorge J; Velázquez-Cruz, Rafael R
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.
Nature Genetics
Dunning, Alison M AM; Michailidou, Kyriaki K; Kuchenbaecker, Karoline B KB; Thompson, Deborah D; French, Juliet D JD; Beesley, Jonathan J; Healey, Catherine S CS; Kar, Siddhartha S; Pooley, Karen A KA; Lopez-Knowles, Elena E; Dicks, Ed E; Barrowdale, Daniel D; Sinnott-Armstrong, Nicholas A NA; Sallari, Richard C RC; Hillman, Kristine M KM; Kaufmann, Susanne S; Sivakumaran, Haran H; Moradi Marjaneh, Mahdi M; Lee, Jason S JS; Hills, Margaret M; Jarosz, Monika M; Drury, Suzie S; Canisius, Sander S; Bolla, Manjeet K MK; Dennis, Joe J; Wang, Qin Q; Hopper, John L JL; Southey, Melissa C MC; Broeks, Annegien A; Schmidt, Marjanka K MK; Lophatananon, Artitaya A; Muir, Kenneth K; Beckmann, Matthias W MW; Fasching, Peter A PA; Dos-Santos-Silva, Isabel I; Peto, Julian J; Sawyer, Elinor J EJ; Tomlinson, Ian I; Burwinkel, Barbara B; Marme, Frederik F; Guénel, Pascal P; Truong, Thérèse T; Bojesen, Stig E SE; Flyger, Henrik H; González-Neira, Anna A; Perez, Jose I A JI; Anton-Culver, Hoda H; Eunjung, Lee L; Arndt, Volker V; Brenner, Hermann H; Meindl, Alfons A; Schmutzler, Rita K RK; Brauch, Hiltrud H; Hamann, Ute U; Aittomäki, Kristiina K; Blomqvist, Carl C; Ito, Hidemi H; Matsuo, Keitaro K; Bogdanova, Natasha N; Dörk, Thilo T; Lindblom, Annika A; Margolin, Sara S; Kosma, Veli-Matti VM; Mannermaa, Arto A; Tseng, Chiu-Chen CC; Wu, Anna H AH; Lambrechts, Diether D; Wildiers, Hans H; Chang-Claude, Jenny J; Rudolph, Anja A; Peterlongo, Paolo P; Radice, Paolo P; Olson, Janet E JE; Giles, Graham G GG; Milne, Roger L RL; Haiman, Christopher A CA; Henderson, Brian E BE; Goldberg, Mark S MS; Teo, Soo H SH; Yip, Cheng Har CH; Nord, Silje S; Borresen-Dale, Anne-Lise AL; Kristensen, Vessela V; Long, Jirong J; Zheng, Wei W; Pylkäs, Katri K; Winqvist, Robert R; Andrulis, Irene L IL; Knight, Julia A JA; Devilee, Peter P; Seynaeve, Caroline C; Figueroa, Jonine J; Sherman, Mark E ME; Czene, Kamila K; Darabi, Hatef H; Hollestelle, Antoinette A; van den Ouweland, Ans M W AM; Humphreys, Keith K; Gao, Yu-Tang YT; Shu, Xiao-Ou XO; Cox, Angela A; Cross, Simon S SS; Blot, William W; Cai, Qiuyin Q; Ghoussaini, Maya M; Perkins, Barbara J BJ; Shah, Mitul M; Choi, Ji-Yeob JY; Kang, Daehee D; Lee, Soo Chin SC; Hartman, Mikael M; Kabisch, Maria M; Torres, Diana D; Jakubowska, Anna A; Lubinski, Jan J; Brennan, Paul P; Sangrajrang, Suleeporn S; Ambrosone, Christine B CB; Toland, Amanda E AE; Shen, Chen-Yang CY; Wu, Pei-Ei PE; Orr, Nick N; Swerdlow, Anthony A; McGuffog, Lesley L; Healey, Sue S; Lee, Andrew A; Kapuscinski, Miroslav M; John, Esther M EM; Terry, Mary Beth MB; Daly, Mary B MB; Goldgar, David E DE; Buys, Saundra S SS; Janavicius, Ramunas R; Tihomirova, Laima L; Tung, Nadine N; Dorfling, Cecilia M CM; van Rensburg, Elizabeth J EJ; Neuhausen, Susan L SL; Ejlertsen, Bent B; Hansen, Thomas V O TV; Osorio, Ana A; Benitez, Javier J; Rando, Rachel R; Weitzel, Jeffrey N JN; Bonanni, Bernardo B; Peissel, Bernard B; Manoukian, Siranoush S; Papi, Laura L; Ottini, Laura L; Konstantopoulou, Irene I; Apostolou, Paraskevi P; Garber, Judy J; Rashid, Muhammad Usman MU; Frost, Debra D; , ; Izatt, Louise L; Ellis, Steve S; Godwin, Andrew K AK; Arnold, Norbert N; Niederacher, Dieter D; Rhiem, Kerstin K; Bogdanova-Markov, Nadja N; Sagne, Charlotte C; Stoppa-Lyonnet, Dominique D; Damiola, Francesca F; , ; Sinilnikova, Olga M OM; Mazoyer, Sylvie S; Isaacs, Claudine C; Claes, Kathleen B M KB; De Leeneer, Kim K; de la Hoya, Miguel M; Caldes, Trinidad T; Nevanlinna, Heli H; Khan, Sofia S; Mensenkamp, Arjen R AR; , ; Hooning, Maartje J MJ; Rookus, Matti A MA; Kwong, Ava A; Olah, Edith E; Diez, Orland O; Brunet, Joan J; Pujana, Miquel Angel MA; Gronwald, Jacek J; Huzarski, Tomasz T; Barkardottir, Rosa B RB; Laframboise, Rachel R; Soucy, Penny P; Montagna, Marco M; Agata, Simona S; Teixeira, Manuel R MR; , ; Park, Sue Kyung SK; Lindor, Noralane N; Couch, Fergus J FJ; Tischkowitz, Marc M; Foretova, Lenka L; Vijai, Joseph J; Offit, Kenneth K; Singer, Christian F CF; Rappaport, Christine C; Phelan, Catherine M CM; Greene, Mark H MH; Mai, Phuong L PL; Rennert, Gad G; Imyanitov, Evgeny N EN; Hulick, Peter J PJ; Phillips, Kelly-Anne KA; Piedmonte, Marion M; Mulligan, Anna Marie AM; Glendon, Gord G; Bojesen, Anders A; Thomassen, Mads M; Caligo, Maria A MA; Yoon, Sook-Yee SY; Friedman, Eitan E; Laitman, Yael Y; Borg, Ake A; von Wachenfeldt, Anna A; Ehrencrona, Hans H; Rantala, Johanna J; Olopade, Olufunmilayo I OI; Ganz, Patricia A PA; Nussbaum, Robert L RL; Gayther, Simon A SA; Nathanson, Katherine L KL; Domchek, Susan M SM; Arun, Banu K BK; Mitchell, Gillian G; Karlan, Beth Y BY; Lester, Jenny J; Maskarinec, Gertraud G; Woolcott, Christy C; Scott, Christopher C; Stone, Jennifer J; Apicella, Carmel C; Tamimi, Rulla R; Luben, Robert R; Khaw, Kay-Tee KT; Helland, Åslaug Å; Haakensen, Vilde V; Dowsett, Mitch M; Pharoah, Paul D P PD; Simard, Jacques J; Hall, Per P; García-Closas, Montserrat M; Vachon, Celine C; Chenevix-Trench, Georgia G; Antoniou, Antonis C AC; Easton, Douglas F DF; Edwards, Stacey L SL
Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women.
Journal Of Bone And Mineral Research : The Official Journal Of The American Society For Bone And Mineral Research
Koller, Daniel L DL; Zheng, Hou-Feng HF; Karasik, David D; Yerges-Armstrong, Laura L; Liu, Ching-Ti CT; McGuigan, Fiona F; Kemp, John P JP; Giroux, Sylvie S; Lai, Dongbing D; Edenberg, Howard J HJ; Peacock, Munro M; Czerwinski, Stefan A SA; Choh, Audrey C AC; McMahon, George G; St Pourcain, Beate B; Timpson, Nicholas J NJ; Lawlor, Debbie A DA; Evans, David M DM; Towne, Bradford B; Blangero, John J; Carless, Melanie A MA; Kammerer, Candace C; Goltzman, David D; Kovacs, Christopher S CS; Prior, Jerilynn C JC; Spector, Tim D TD; Rousseau, Francois F; Tobias, Jon H JH; Akesson, Kristina K; Econs, Michael J MJ; Mitchell, Braxton D BD; Richards, J Brent JB; Kiel, Douglas P DP; Foroud, Tatiana T
Impact of common variation in bone-related genes on type 2 diabetes and related traits.
Diabetes
Billings, Liana K LK; Hsu, Yi-Hsiang YH; Ackerman, Rachel J RJ; Dupuis, Josée J; Voight, Benjamin F BF; Rasmussen-Torvik, Laura J LJ; Hercberg, Serge S; Lathrop, Mark M; Barnes, Daniel D; Langenberg, Claudia C; Hui, Jennie J; Fu, Mao M; Bouatia-Naji, Nabila N; Lecoeur, Cecile C; An, Ping P; Magnusson, Patrik K PK; Surakka, Ida I; Ripatti, Samuli S; Christiansen, Lene L; Dalgård, Christine C; Folkersen, Lasse L; Grundberg, Elin E; , ; , ; , ; , ; , ; Eriksson, Per P; Kaprio, Jaakko J; Ohm Kyvik, Kirsten K; Pedersen, Nancy L NL; Borecki, Ingrid B IB; Province, Michael A MA; Balkau, Beverley B; Froguel, Philippe P; Shuldiner, Alan R AR; Palmer, Lyle J LJ; Wareham, Nick N; Meneton, Pierre P; Johnson, Toby T; Pankow, James S JS; Karasik, David D; Meigs, James B JB; Kiel, Douglas P DP; Florez, Jose C JC
Common genetic variants are associated with accelerated bone mineral density loss after hematopoietic cell transplantation.
Plos One
Yao, Song S; Sucheston, Lara E LE; Smiley, Shannon L SL; Davis, Warren W; Conroy, Jeffrey M JM; Nowak, Norma J NJ; Ambrosone, Christine B CB; McCarthy, Philip L PL; Hahn, Theresa T
Meta-analysis of gene-based genome-wide association studies of bone mineral density in Chinese and European subjects.
Osteoporosis International : A Journal Established As Result Of Cooperation Between The European Foundation For Osteoporosis And The National Osteoporosis Foundation Of The Usa
Cheung, C-L CL; Sham, P-C PC; Xiao, S-M SM; Bow, C H CH; Kung, A W-C AW
The ESR1 (6q25) locus is associated with calcaneal ultrasound parameters and radial volumetric bone mineral density in European men.
Plos One
Holliday, Kate L KL; Pye, Stephen R SR; Thomson, Wendy W; Boonen, Steven S; Borghs, Herman H; Vanderschueren, Dirk D; Gielen, Evelien E; Huhtaniemi, Ilpo T IT; Adams, Judith E JE; Ward, Kate A KA; Bartfai, Gyorgy G; Casanueva, Felipe F; Finn, Joseph D JD; Forti, Gianni G; Giwercman, Aleksander A; Han, Thang S TS; Kula, Krzysztof K; Labrie, Fernand F; Lean, Michael E J ME; Pendleton, Neil N; Punab, Margus M; Wu, Frederick C W FC; O'Neill, Terence W TW; ,
European bone mineral density loci are also associated with BMD in East-Asian populations.
Plos One
Styrkarsdottir, Unnur U; Halldorsson, Bjarni V BV; Gudbjartsson, Daniel F DF; Tang, Nelson L S NL; Koh, Jung-Min JM; Xiao, Su-mei SM; Kwok, Timothy C Y TC; Kim, Ghi Su GS; Chan, Juliana C N JC; Cherny, Stacey S; Lee, Seung Hun SH; Kwok, Anthony A; Ho, Suzanne S; Gretarsdottir, Solveig S; Kostic, Jelena Pop JP; Palsson, Stefan Th ST; Sigurdsson, Gunnar G; Sham, Pak C PC; Kim, Beom-Jun BJ; Kung, Annie W C AW; Kim, Shin-Yoon SY; Woo, Jean J; Leung, Ping-C PC; Kong, Augustine A; Thorsteinsdottir, Unnur U; Stefansson, Kari K
Replication study of candidate genes/loci associated with osteoporosis based on genome-wide screening.
Osteoporosis International : A Journal Established As Result Of Cooperation Between The European Foundation For Osteoporosis And The National Osteoporosis Foundation Of The Usa
Common variants in the region around Osterix are associated with bone mineral density and growth in childhood.
Human Molecular Genetics
Timpson, Nicholas J NJ; Tobias, Jon H JH; Richards, J Brent JB; Soranzo, Nicole N; Duncan, Emma L EL; Sims, Anne-Marie AM; Whittaker, Pamela P; Kumanduri, Vasudev V; Zhai, Guangju G; Glaser, Beate B; Eisman, John J; Jones, Graeme G; Nicholson, Geoff G; Prince, Richard R; Seeman, Ego E; Spector, Tim D TD; Brown, Matthew A MA; Peltonen, Leena L; Smith, George Davey GD; Deloukas, Panos P; Evans, David M DM