CRISPR screens identify gene targets at breast cancer risk loci.
Genome Biology
Tuano, Natasha K NK; Beesley, Jonathan J; Manning, Murray M; Shi, Wei W; Perlaza-Jimenez, Laura L; Malaver-Ortega, Luis F LF; Paynter, Jacob M JM; Black, Debra D; Civitarese, Andrew A; McCue, Karen K; Hatzipantelis, Aaron A; Hillman, Kristine K; Kaufmann, Susanne S; Sivakumaran, Haran H; Polo, Jose M JM; Reddel, Roger R RR; Band, Vimla V; French, Juliet D JD; Edwards, Stacey L SL; Powell, David R DR; Chenevix-Trench, Georgia G; Rosenbluh, Joseph J
On-treatment derived neutrophil-to-lymphocyte ratio and survival with palbociclib and endocrine treatment: analysis of a multicenter retrospective cohort and the PALOMA-2/3 study with immune correlates.
Breast Cancer Research : Bcr
Kim, Chang Gon CG; Kim, Min Hwan MH; Kim, Jee Hung JH; Kim, Seul-Gi SG; Kim, Gun Min GM; Kim, Tae Yeong TY; Ryu, Won-Ji WJ; Kim, Jee Ye JY; Park, Hyung Seok HS; Park, Seho S; Cho, Young Up YU; Park, Byeong Woo BW; Kim, Seung Il SI; Jeong, Joon J; Sohn, Joohyuk J
Paper-based laser-induced graphene for sustainable and flexible microsupercapacitor applications.
Mikrochimica Acta
Coelho, João J; Correia, Ricardo F RF; Silvestre, Sara S; Pinheiro, Tomás T; Marques, Ana C AC; Correia, M Rosário P MRP; Pinto, Joana Vaz JV; Fortunato, Elvira E; Martins, Rodrigo R
SETD7 Expression Is Associated with Breast Cancer Survival Outcomes for Specific Molecular Subtypes: A Systematic Analysis of Publicly Available Datasets.
Cancers
Monteiro, Fátima Liliana FL; Stepanauskaite, Lina L; Williams, Cecilia C; Helguero, Luisa A LA
A bimodal type of AgPd Plasmonic Blackbody Nanozyme with boosted catalytic efficacy and synergized photothermal therapy for efficacious tumor treatment in the second biological window.
Journal Of Nanobiotechnology
Jia, Tao T; Li, Dan D; Du, Jiarui J; Fang, Xikui X; Gerasimov, Valeriy V; Ågren, Hans H; Chen, Guanying G
Spectroscopic studies reveal details of substrate-induced conformational changes distant from the active site in isopenicillin N synthase.
The Journal Of Biological Chemistry
Rabe, Patrick P; Walla, Carla C CC; Goodyear, Noelle K NK; Welsh, Jordan J; Southwart, Rebecca R; Clifton, Ian I; Linyard, James D S JDS; Tumber, Anthony A; Claridge, Tim D W TDW; Myers, William K WK; Schofield, Christopher J CJ
A natural fusion of flavodiiron, rubredoxin, and rubredoxin oxidoreductase domains is a self-sufficient water-forming oxidase of Trichomonas vaginalis.
The Journal Of Biological Chemistry
Abdulaziz, Evana N EN; Bell, Tristan A TA; Rashid, Bazlur B; Heacock, Mina L ML; Begic, Tarik T; Skinner, Owen S OS; Yaseen, Mohammad A MA; Chao, Luke H LH; Mootha, Vamsi K VK; Pierik, Antonio J AJ; Cracan, Valentin V
A novel chemo-phenotypic method identifies mixtures of salpn, vitamin D3, and pesticides involved in the development of colorectal and pancreatic cancer.
Ecotoxicology And Environmental Safety
Issa, Naiem T NT; Wathieu, Henri H; Glasgow, Eric E; Peran, Ivana I; Parasido, Erika E; Li, Tianqi T; Simbulan-Rosenthal, Cynthia M CM; Rosenthal, Dean D; Medvedev, Alexander V AV; Makarov, Sergei S SS; Albanese, Christopher C; Byers, Stephen W SW; Dakshanamurthy, Sivanesan S
Proteomic analysis of archival breast cancer clinical specimens identifies biological subtypes with distinct survival outcomes.
Nature Communications
Asleh, Karama K; Negri, Gian Luca GL; Spencer Miko, Sandra E SE; Colborne, Shane S; Hughes, Christopher S CS; Wang, Xiu Q XQ; Gao, Dongxia D; Gilks, C Blake CB; Chia, Stephen K L SKL; Nielsen, Torsten O TO; Morin, Gregg B GB
Regulation of AR mRNA translation in response to acute AR pathway inhibition.
Nucleic Acids Research
Somasekharan, Syam Prakash SP; Saxena, Neetu N; Zhang, Fan F; Beraldi, Eliana E; Huang, Jia Ni JN; Gentle, Christina C; Fazli, Ladan L; Thi, Marisa M; Sorensen, Poul H PH; Gleave, Martin M
Regulation of AR mRNA translation in response to acute AR pathway inhibition.
Nucleic Acids Research
Somasekharan, Syam Prakash SP; Saxena, Neetu N; Zhang, Fan F; Beraldi, Eliana E; Huang, Jia Ni JN; Gentle, Christina C; Fazli, Ladan L; Thi, Marisa M; Sorensen, Poul H PH; Gleave, Martin M
Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19.
Cells
D'Alessandro, Angelo A; Thomas, Tiffany T; Akpan, Imo J IJ; Reisz, Julie A JA; Cendali, Francesca I FI; Gamboni, Fabia F; Nemkov, Travis T; Thangaraju, Kiruphagaran K; Katneni, Upendra U; Tanaka, Kenichi K; Kahn, Stacie S; Wei, Alexander Z AZ; Valk, Jacob E JE; Hudson, Krystalyn E KE; Roh, David D; Moriconi, Chiara C; Zimring, James C JC; Hod, Eldad A EA; Spitalnik, Steven L SL; Buehler, Paul W PW; Francis, Richard O RO
Diagnosis and management of community-acquired pneumonia in children: South African Thoracic Society guidelines.
African Journal Of Thoracic And Critical Care Medicine
Zar, H J HJ; Moore, D P DP; Andronikou, S S; Argent, A C AC; Avenant, T T; Cohen, C C; Green, R J RJ; Itzikowitz, G G; Jeena, P P; Masekela, R R; Nicol, M P MP; Pillay, A A; Reubenson, G G; Madhi, S A SA
Genomic and Transcriptomic Analyses of Breast Cancer Primaries and Matched Metastases in AURORA, the Breast International Group (BIG) Molecular Screening Initiative.
Cancer Discovery
Aftimos, Philippe P; Oliveira, Mafalda M; Irrthum, Alexandre A; Fumagalli, Debora D; Sotiriou, Christos C; Gal-Yam, Einav Nili EN; Robson, Mark E ME; Ndozeng, Justin J; Di Leo, Angelo A; Ciruelos, Eva M EM; de Azambuja, Evandro E; Viale, Giuseppe G; Scheepers, Elsemieke D ED; Curigliano, Giuseppe G; Bliss, Judith M JM; Reis-Filho, Jorge S JS; Colleoni, Marco M; Balic, Marija M; Cardoso, Fatima F; Albanell, Joan J; Duhem, Caroline C; Marreaud, Sandrine S; Romagnoli, Dario D; Rojas, Beatriz B; Gombos, Andrea A; Wildiers, Hans H; Guerrero-Zotano, Angel A; Hall, Peter P; Bonetti, Andrea A; Larsson, Karolina Fs KF; Degiorgis, Martina M; Khodaverdi, Silvia S; Greil, Richard R; Sverrisdóttir, Ásgerdur Á; Paoli, Marta M; Seyll, Ethel E; Loibl, Sibylle S; Linderholm, Barbro B; Zoppoli, Gabriele G; Davidson, Nancy E NE; Johannsson, Oskar Th OT; Bedard, Philippe L PL; Loi, Sherene S; Knox, Susan S; Cameron, David A DA; Harbeck, Nadia N; Montoya, Maite Lasa ML; Brandão, Mariana M; Vingiani, Andrea A; Caballero, Carmela C; Hilbers, Florentine S FS; Yates, Lucy R LR; Benelli, Matteo M; Venet, David D; Piccart, Martine J MJ
High estrogen receptor alpha activation confers resistance to estrogen deprivation and is required for therapeutic response to estrogen in breast cancer.
Oncogene
Traphagen, Nicole A NA; Hosford, Sarah R SR; Jiang, Amanda A; Marotti, Jonathan D JD; Brauer, Brooke L BL; Demidenko, Eugene E; Miller, Todd W TW
High estrogen receptor alpha activation confers resistance to estrogen deprivation and is required for therapeutic response to estrogen in breast cancer.
Oncogene
Traphagen, Nicole A NA; Hosford, Sarah R SR; Jiang, Amanda A; Marotti, Jonathan D JD; Brauer, Brooke L BL; Demidenko, Eugene E; Miller, Todd W TW
CD52 Is Elevated on B cells of SLE Patients and Regulates B Cell Function.
Frontiers In Immunology
Bhamidipati, Kartik K; Silberstein, John L JL; Chaichian, Yashaar Y; Baker, Matthew C MC; Lanz, Tobias V TV; Zia, Amin A; Rasheed, Yusuf S YS; Cochran, Jennifer R JR; Robinson, William H WH
PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington's disease.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Morozko, Eva L EL; Smith-Geater, Charlene C; Monteys, Alejandro Mas AM; Pradhan, Subrata S; Lim, Ryan G RG; Langfelder, Peter P; Kachemov, Marketta M; Kulkarni, Jayesh A JA; Zaifman, Josh J; Hill, Austin A; Stocksdale, Jennifer T JT; Cullis, Pieter R PR; Wu, Jie J; Ochaba, Joseph J; Miramontes, Ricardo R; Chakraborty, Anirban A; Hazra, Tapas K TK; Lau, Alice A; St-Cyr, Sophie S; Orellana, Iliana I; Kopan, Lexi L; Wang, Keona Q KQ; Yeung, Sylvia S; Leavitt, Blair R BR; Reidling, Jack C JC; Yang, X William XW; Steffan, Joan S JS; Davidson, Beverly L BL; Sarkar, Partha S PS; Thompson, Leslie M LM
Steroid Hormone Receptor and Infiltrating Immune Cell Status Reveals Therapeutic Vulnerabilities of ESR1-Mutant Breast Cancer.
Cancer Research
Williams, Michelle M MM; Spoelstra, Nicole S NS; Arnesen, Spencer S; O'Neill, Kathleen I KI; Christenson, Jessica L JL; Reese, Jordan J; Torkko, Kathleen C KC; Goodspeed, Andrew A; Rosas, Emmanuel E; Hanamura, Toru T; Sams, Sharon B SB; Li, Zheqi Z; Oesterreich, Steffi S; Riggins, Rebecca B RB; Jacobsen, Britta M BM; Elias, Anthony A; Gertz, Jason J; Richer, Jennifer K JK
Engineered chemotaxis core signaling units indicate a constrained kinase-off state.
Science Signaling
Muok, Alise R AR; Chua, Teck Khiang TK; Srivastava, Madhur M; Yang, Wen W; Maschmann, Zach Z; Borbat, Petr P PP; Chong, Jenna J; Zhang, Sheng S; Freed, Jack H JH; Briegel, Ariane A; Crane, Brian R BR
Electrothermal soft manipulator enabling safe transport and handling of thin cell/tissue sheets and bioelectronic devices.
Science Advances
Kim, Byoung Soo BS; Kim, Min Ku MK; Cho, Younghak Y; Hamed, Eman E EE; Gillette, Martha U MU; Cha, Hyeongyun H; Miljkovic, Nenad N; Aakalu, Vinay K VK; Kang, Kai K; Son, Kyung-No KN; Schachtschneider, Kyle M KM; Schook, Lawrence B LB; Hu, Chenfei C; Popescu, Gabriel G; Park, Yeonsoo Y; Ballance, William C WC; Yu, Seunggun S; Im, Sung Gap SG; Lee, Jonghwi J; Lee, Chi Hwan CH; Kong, Hyunjoon H