Publications:

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Endocrine Resistance in Breast Cancer: The Role of Estrogen Receptor Stability.

Cells

Jeffreys, Sarah A SA; Powter, Branka B; Balakrishnar, Bavanthi B; Mok, Kelly K; Soon, Patsy P; Franken, André A; Neubauer, Hans H; de Souza, Paul P; Becker, Therese M TM

Publication Date: 2020-09-11

Variant appearance in text: ESR1: S118A

PubMed Link: 32932819

Variant Present in the following documents:

• Main text
• cells-09-02077.pdf

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Notch Signaling Pathway and Endocrine Resistance in Breast Cancer.

Frontiers In Pharmacology

Bai, Jing-Wen JW; Wei, Min M; Li, Ji-Wei JW; Zhang, Guo-Jun GJ

Publication Date: 2020

Variant appearance in text: ESR1: S118A

PubMed Link: 32636747

Variant Present in the following documents:

• Main text
• fphar-11-00924.pdf

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The estrogen receptor-alpha S118P variant does not affect breast cancer incidence or response to endocrine therapies.

Breast Cancer Research And Treatment

Button, Berry B; Croessmann, Sarah S; Chu, David D; Rosen, D Marc DM; Zabransky, Daniel J DJ; Dalton, W Brian WB; Cravero, Karen K; Kyker-Snowman, Kelly K; Waters, Ian I; Karthikeyan, Swathi S; Christenson, Eric S ES; Donaldson, Josh J; Hunter, Tasha T; Dennison, Lauren L; Ramin, Cody C; May, Betty B; Roden, Richard R; Petry, Dana D; Armstrong, Deborah K DK; Visvanathan, Kala K; Park, Ben Ho BH

Publication Date: 2019-04

Variant appearance in text: ESR1: S118A

PubMed Link: 30560461

Variant Present in the following documents:

• Main text

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Feedback control of the CXCR7/CXCL11 chemokine axis by estrogen receptor α in ovarian cancer.

Molecular Oncology

Benhadjeba, Samira S; Edjekouane, Lydia L; Sauvé, Karine K; Carmona, Euridice E; Tremblay, André A

Publication Date: 2018-10

Variant appearance in text: ESR1: S118A

PubMed Link: 30051594

Variant Present in the following documents:

• Main text
• MOL2-12-1689.pdf
• MOL2-12-1689-s001.pdf

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ERpS294 is a biomarker of ligand or mutational ERα activation and a breast cancer target for CDK2 inhibition.

Oncotarget

Scott, Gary K GK; Chu, David D; Kaur, Ravneet R; Malato, Julia J; Rothschild, Daniel E DE; Frazier, Katya K; Eppenberger-Castori, Serenella S; Hann, Byron B; Park, Ben Ho BH; Benz, Christopher C CC

Publication Date: 2017-10-13

Variant appearance in text: ESR1: S118A

PubMed Link: 29137354

Variant Present in the following documents:

• Main text
• oncotarget-08-83432.pdf

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Endometrial cancer-associated mutants of SPOP are defective in regulating estrogen receptor-α protein turnover.

Cell Death & Disease

Zhang, P P; Gao, K K; Jin, X X; Ma, J J; Peng, J J; Wumaier, R R; Tang, Y Y; Zhang, Y Y; An, J J; Yan, Q Q; Dong, Y Y; Huang, H H; Yu, L L; Wang, C C

Publication Date: 2015-03-12

Variant appearance in text: ESR1: S118A

PubMed Link: 25766326

Variant Present in the following documents:

• Main text
• cddis201547a.pdf

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BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

Molecular Endocrinology (Baltimore, Md.)

Ma, Yongxian Y; Fan, Saijun S; Hu, Changyan C; Meng, Qinghui Q; Fuqua, Suzanne A SA; Pestell, Richard G RG; Tomita, York A YA; Rosen, Eliot M EM

Publication Date: 2010-01

Variant appearance in text: ER-alpha: S118A

PubMed Link: 19887647

Variant Present in the following documents:

• Main text

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Formation of an hER alpha-COUP-TFI complex enhances hER alpha AF-1 through Ser118 phosphorylation by MAPK.

The Embo Journal

Métivier, Raphaël R; Gay, Frédérique A FA; Hübner, Michael R MR; Flouriot, Gilles G; Salbert, Gilles G; Gannon, Frank F; Kah, Olivier O; Pakdel, Farzad F

Publication Date: 2002-07-01

Variant appearance in text: NR3A1: S118A

PubMed Link: 12093745

Variant Present in the following documents:

• Main text

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