ESR1 c.1159_1160delinsGC ;(p.L387A)

Variant ID: 6-152332853-CT-GC

NM_000125.3(ESR1):c.1159_1160delinsGC;(p.L387A)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


The effect of protein mutations on drug binding suggests ensuing personalised drug selection.

Scientific Reports
Wan, Shunzhou S; Kumar, Deepak D; Ilyin, Valentin V; Al Homsi, Ussama U; Sher, Gulab G; Knuth, Alexander A; Coveney, Peter V PV
Publication Date: 2021-06-29

Variant appearance in text: ESR1: L387A
PubMed Link: 34188094
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_92785.pdf
View BVdb publication page



A new class of small molecule estrogen receptor-alpha antagonists that overcome anti-estrogen resistance.

Oncotarget
Ma, Yongxian Y; Preet, Anju A; Tomita, York Y; De Oliveira, Eliseu E; Zhang, Li L; Ueda, Yumi Y; Clarke, Robert R; Brown, Milton M; Rosen, Eliot M EM
Publication Date: 2015-12-01

Variant appearance in text: ER-alpha: Leu387Ala
PubMed Link: 26575173
Variant Present in the following documents:
  • Main text
  • oncotarget-06-40388.pdf
View BVdb publication page