Publications:

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Molecular profiling of a real-world breast cancer cohort with genetically inferred ancestries reveals actionable tumor biology differences between European ancestry and African ancestry patient populations.

Breast Cancer Research : Bcr

Miyashita, Minoru M; Bell, Joshua S K JSK; Wenric, Stephane S; Karaesmen, Ezgi E; Rhead, Brooke B; Kase, Matthew M; Kaneva, Kristiyana K; De La Vega, Francisco M FM; Zheng, Yonglan Y; Yoshimatsu, Toshio F TF; Khramtsova, Galina G; Liu, Fang F; Zhao, Fangyuan F; Howard, Frederick M FM; Nanda, Rita R; Beaubier, Nike N; White, Kevin P KP; Huo, Dezheng D; Olopade, Olufunmilayo I OI

Publication Date: 2023-05-25

Variant appearance in text: ESR1: 1607T>G; L536R

PubMed Link: 37231433

Variant Present in the following documents:

• 13058_2023_1627_MOESM4_ESM.xlsx, sheet 2

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Phase 1 study of oral selective estrogen receptor degrader (SERD) amcenestrant (SAR439859), in Japanese women with ER-positive and HER2-negative advanced breast cancer (AMEERA-2).

Breast Cancer (Tokyo, Japan)

Tamura, Kenji K; Mukohara, Toru T; Yonemori, Kan K; Kawabata, Yumiko Y; Nicolas, Xavier X; Tanaka, Tomoyuki T; Iwata, Hiroji H

Publication Date: 2023-03-29

Variant appearance in text: ESR1: L536R

PubMed Link: 36977973

Variant Present in the following documents:

• 12282_2023_Article_1443.pdf

View BVdb publication page

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Comprehensive liquid biopsy analysis as a tool for the early detection of minimal residual disease in breast cancer.

Scientific Reports

Stergiopoulou, Dimitra D; Markou, Athina A; Strati, Areti A; Zavridou, Martha M; Tzanikou, Eleni E; Mastoraki, Sophia S; Kallergi, Galatea G; Georgoulias, Vassilis V; Lianidou, Evi E

Publication Date: 2023-01-23

Variant appearance in text: ESR1: L536R

PubMed Link: 36690653

Variant Present in the following documents:

• Main text
• 41598_2022_Article_25400.pdf

View BVdb publication page

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ESR1 gene amplification and MAP3K mutations are selected during adjuvant endocrine therapies in relapsing Hormone Receptor-positive, HER2-negative breast cancer (HR+ HER2- BC).

Plos Genetics

Ferrando, Lorenzo L; Vingiani, Andrea A; Garuti, Anna A; Vernieri, Claudio C; Belfiore, Antonino A; Agnelli, Luca L; Dagrada, Gianpaolo G; Ivanoiu, Diana D; Bonizzi, Giuseppina G; Munzone, Elisabetta E; Lippolis, Luana L; Dameri, Martina M; Ravera, Francesco F; Colleoni, Marco M; Viale, Giuseppe G; Magnani, Luca L; Ballestrero, Alberto A; Zoppoli, Gabriele G; Pruneri, Giancarlo G

Publication Date: 2023-01-03

Variant appearance in text: rs1057519717

PubMed Link: 36595552

Variant Present in the following documents:

• pgen.1010563.s004.xlsx, sheet 1

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The Clinical Utility of Droplet Digital PCR for Profiling Circulating Tumor DNA in Breast Cancer Patients.

Diagnostics (Basel, Switzerland)

Gezer, Ugur U; Bronkhorst, Abel J AJ; Holdenrieder, Stefan S

Publication Date: 2022-12-05

Variant appearance in text: ESR1: L536R

PubMed Link: 36553049

Variant Present in the following documents:

• Main text
• diagnostics-12-03042.pdf

View BVdb publication page

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Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer.

Nature Communications

Sivakumar, Smruthy S; Jin, Dexter X DX; Tukachinsky, Hanna H; Murugesan, Karthikeyan K; McGregor, Kimberly K; Danziger, Natalie N; Pavlick, Dean D; Gjoerup, Ole O; Ross, Jeffrey S JS; Harmon, Robert R; Chung, Jon J; Decker, Brennan B; Dennis, Lucas L; Frampton, Garrett M GM; Molinero, Luciana L; Oesterreich, Steffi S; Venstrom, Jeffrey M JM; Oxnard, Geoffrey R GR; Hegde, Priti S PS; Sokol, Ethan S ES

Publication Date: 2022-12-05

Variant appearance in text: ESR1: L536R

PubMed Link: 36470901

Variant Present in the following documents:

• 41467_2022_35245_MOESM4_ESM.xlsx, sheet 17

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Genome engineering for estrogen receptor mutations reveals differential responses to anti-estrogens and new prognostic gene signatures for breast cancer.

Oncogene

Harrod, Alison A; Lai, Chun-Fui CF; Goldsbrough, Isabella I; Simmons, Georgia M GM; Oppermans, Natasha N; Santos, Daniela B DB; Győrffy, Balazs B; Allsopp, Rebecca C RC; Toghill, Bradley J BJ; Balachandran, Kirsty K; Lawson, Mandy M; Morrow, Christopher J CJ; Surakala, Manasa M; Carnevalli, Larissa S LS; Zhang, Pei P; Guttery, David S DS; Shaw, Jacqueline A JA; Coombes, R Charles RC; Buluwela, Lakjaya L; Ali, Simak S

Publication Date: 2022-10

Variant appearance in text: ESR1: L536R

PubMed Link: 36198774

Variant Present in the following documents:

• Main text
• 41388_2022_Article_2483.pdf
• 41388_2022_2483_MOESM2_ESM.pdf
• 41388_2022_2483_MOESM1_ESM.pdf

View BVdb publication page

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Improving prediction of response to neoadjuvant treatment in patients with breast cancer by combining liquid biopsies with multiparametric MRI: protocol of the LIMA study - a multicentre prospective observational cohort study.

Bmj Open

Janssen, Liselore M LM; Suelmann, Britt B M BBM; Elias, Sjoerd G SG; Janse, Markus H A MHA; van Diest, Paul J PJ; van der Wall, Elsken E; Gilhuijs, Kenneth G A KGA

Publication Date: 2022-09-20

Variant appearance in text: ESR1: L536R

PubMed Link: 36127090

Variant Present in the following documents:

• bmjopen-2022-061334supp001.pdf
• bmjopen-2022-061334.reviewer_comments.pdf

View BVdb publication page

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CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience

Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X

Publication Date: 2022-09-16

Variant appearance in text: ESR1: 1607T>G; L536R

PubMed Link: 36117989

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

View BVdb publication page

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Integrative genomic and transcriptomic analyses illuminate the ontology of HER2-low breast carcinomas.

Genome Medicine

Berrino, Enrico E; Annaratone, Laura L; Bellomo, Sara Erika SE; Ferrero, Giulio G; Gagliardi, Amedeo A; Bragoni, Alberto A; Grassini, Dora D; Guarrera, Simonetta S; Parlato, Caterina C; Casorzo, Laura L; Panero, Mara M; Sarotto, Ivana I; Giordano, Silvia S; Cereda, Matteo M; Montemurro, Filippo F; Ponzone, Riccardo R; Crosetto, Nicola N; Naccarati, Alessio A; Sapino, Anna A; Marchiò, Caterina C

Publication Date: 2022-08-29

Variant appearance in text: ESR1: L536R

PubMed Link: 36038884

Variant Present in the following documents:

• 13073_2022_1104_MOESM8_ESM.xlsx, sheet 1

View BVdb publication page

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The circulating tumor DNA (ctDNA) alteration level predicts therapeutic response in metastatic breast cancer: Novel prognostic indexes based on ctDNA.

Breast (Edinburgh, Scotland)

Liu, Binliang B; Hu, Zheyu Z; Ran, Jialu J; Xie, Ning N; Tian, Can C; Tang, Yu Y; Ouyang, Quchang Q

Publication Date: 2022-10

Variant appearance in text: ESR1: L536R

PubMed Link: 35926241

Variant Present in the following documents:

• mmc1.xlsx, sheet 1

View BVdb publication page

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Predictors of fulvestrant long-term benefit in hormone receptor-positive/HER2 negative advanced breast cancer.

Scientific Reports

Torrisi, Rosalba R; Vaira, Valentina V; Giordano, Laura L; Destro, Annarita A; Basilico, Vera V; Mazzara, Saveria S; Salvini, Piermario P; Gaudioso, Gabriella G; Fernandes, Bethania B; Rudini, Noemi N; Masci, Giovanna G; Santoro, Armando A

Publication Date: 2022-07-27

Variant appearance in text: ESR1: L536R

PubMed Link: 35896637

Variant Present in the following documents:

• Main text
• 41598_2022_Article_16409.pdf

View BVdb publication page

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AMEERA-1 phase 1/2 study of amcenestrant, SAR439859, in postmenopausal women with ER-positive/HER2-negative advanced breast cancer.

Nature Communications

Bardia, Aditya A; Chandarlapaty, Sarat S; Linden, Hannah M HM; Ulaner, Gary A GA; Gosselin, Alice A; Cartot-Cotton, Sylvaine S; Cohen, Patrick P; Doroumian, Séverine S; Paux, Gautier G; Celanovic, Marina M; Pelekanou, Vasiliki V; Ming, Jeffrey E JE; Ternès, Nils N; Bouaboula, Monsif M; Lee, Joon Sang JS; Bauchet, Anne-Laure AL; Campone, Mario M

Publication Date: 2022-07-15

Variant appearance in text: ESR1: L536R

PubMed Link: 35840573

Variant Present in the following documents:

• Main text
• 41467_2022_Article_31668.pdf

View BVdb publication page

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AACR Project GENIE: 100,000 Cases and Beyond.

Cancer Discovery

Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,

Publication Date: 2022-09-02

Variant appearance in text: ESR1: L536R

PubMed Link: 35819403

Variant Present in the following documents:

• cd-21-1547_supplementary_table_1_suppst1.xlsx, sheet 1

View BVdb publication page

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Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: ESR1: L536R

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

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Global Increase in Breast Cancer Incidence: Risk Factors and Preventive Measures.

Biomed Research International

Kashyap, Dharambir D; Pal, Deeksha D; Sharma, Riya R; Garg, Vivek Kumar VK; Goel, Neelam N; Koundal, Deepika D; Zaguia, Atef A; Koundal, Shubham S; Belay, Assaye A

Publication Date: 2022

Variant appearance in text: ESR1: Leu536Arg

PubMed Link: 35480139

Variant Present in the following documents:

• BMRI2022-9605439.pdf

View BVdb publication page

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Estrogen Receptor Bio-Activities Determine Clinical Endocrine Treatment Options in Estrogen Receptor-Positive Breast Cancer.

Technology In Cancer Research & Treatment

Xia, Song S; Lin, Qiong Q

Publication Date: 2022

Variant appearance in text: ESR1: L536R

PubMed Link: 35450488

Variant Present in the following documents:

• Main text
• 10.1177_15330338221090351.pdf

View BVdb publication page

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Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.

Cancer Medicine

Liu, Binliang B; Yi, Zongbi Z; Guan, Yanfang Y; Ouyang, Quchang Q; Li, Chunxiao C; Guan, Xiuwen X; Lv, Dan D; Li, Lixi L; Zhai, Jingtong J; Qian, Haili H; Xu, Binghe B; Ma, Fei F; Zeng, Yixin Y

Publication Date: 2022-07

Variant appearance in text: ESR1: 1607T>G; L536R

PubMed Link: 35393784

Variant Present in the following documents:

• CAM4-11-2767-s001.xlsx, sheet 1

View BVdb publication page

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Endometrioid Cancer Associated With Endometriosis: From the Seed and Soil Theory to Clinical Practice.

Frontiers In Oncology

Farolfi, Alberto A; Altavilla, Amelia A; Morandi, Luca L; Capelli, Laura L; Chiadini, Elisa E; Prisinzano, Giovanna G; Gurioli, Giorgia G; Molari, Marianna M; Calistri, Daniele D; Foschini, Maria Pia MP; De Giorgi, Ugo U

Publication Date: 2022

Variant appearance in text: ESR1: 1607T>G

PubMed Link: 35359373

Variant Present in the following documents:

• Main text
• fonc-12-859510.pdf

View BVdb publication page

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Precision Oncology in Metastatic Uterine Cancer; Croatian First-Year Experience of the Comprehensive Genomic Profiling in Everyday Clinical Practice.

Pathology Oncology Research : Por

Čerina, Dora D; Matković, Višnja V; Katić, Kristina K; Lovasić, Ingrid Belac IB; Šeparović, Robert R; Canjko, Ivana I; Jakšić, Blanka B; Fröbe, Ana A; Pleština, Stjepko S; Bajić, Žarko Ž; Vrdoljak, Eduard E

Publication Date: 2021

Variant appearance in text: ESR1: L536R

PubMed Link: 34646088

Variant Present in the following documents:

• DataSheet3.xlsx, sheet 1

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: ESR1: L536R

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Clinical Utility of Liquid Biopsy-Based Actionable Mutations Detected via ddPCR.

Biomedicines

Palacín-Aliana, Irina I; García-Romero, Noemí N; Asensi-Puig, Adrià A; Carrión-Navarro, Josefa J; González-Rumayor, Víctor V; Ayuso-Sacido, Ángel Á

Publication Date: 2021-07-28

Variant appearance in text: ESR1: L536R

PubMed Link: 34440110

Variant Present in the following documents:

• Main text

View BVdb publication page

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ESR1 mutation as an emerging clinical biomarker in metastatic hormone receptor-positive breast cancer.

Breast Cancer Research : Bcr

Brett, Jamie O JO; Spring, Laura M LM; Bardia, Aditya A; Wander, Seth A SA

Publication Date: 2021-08-15

Variant appearance in text: ESR1: L536R

PubMed Link: 34392831

Variant Present in the following documents:

• Main text
• 13058_2021_Article_1462.pdf

View BVdb publication page

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Comprehensive characterization of distinct genetic alterations in metastatic breast cancer across various metastatic sites.

Npj Breast Cancer

Cha, Soojin S; Lee, Esak E; Won, Hong-Hee HH

Publication Date: 2021-07-16

Variant appearance in text: ESR1: L536R

PubMed Link: 34272397

Variant Present in the following documents:

• 41523_2021_303_MOESM2_ESM.pdf

View BVdb publication page

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Estrogen receptor-α signaling in post-natal mammary development and breast cancers.

Cellular And Molecular Life Sciences : Cmls

Rusidzé, Mariam M; Adlanmérini, Marine M; Chantalat, Elodie E; Raymond-Letron, I I; Cayre, Surya S; Arnal, Jean-François JF; Deugnier, Marie-Ange MA; Lenfant, Françoise F

Publication Date: 2021-08

Variant appearance in text: ESR1: L536R

PubMed Link: 34156490

Variant Present in the following documents:

• Main text

View BVdb publication page

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Longitudinal Dynamics of Circulating Tumor Cells and Circulating Tumor DNA for Treatment Monitoring in Metastatic Breast Cancer.

Jco Precision Oncology

Gerratana, Lorenzo L; Davis, Andrew A AA; Zhang, Qiang Q; Basile, Debora D; Rossi, Giovanna G; Strickland, Kimberly K; Franzoni, Alessandra A; Allegri, Lorenzo L; Mu, Zhaomei Z; Zhang, Youbin Y; Flaum, Lisa E LE; Damante, Giuseppe G; Gradishar, William John WJ; Platanias, Leonidas C LC; Behdad, Amir A; Yang, Hushan H; Puglisi, Fabio F; Cristofanilli, Massimo M

Publication Date: 2021-06

Variant appearance in text: ESR1: L536R

PubMed Link: 34136741

Variant Present in the following documents:

• po-5-943.pdf

View BVdb publication page

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Preexisting Somatic Mutations of Estrogen Receptor Alpha (ESR1) in Early-Stage Primary Breast Cancer.

Jnci Cancer Spectrum

Dahlgren, Malin M; George, Anthony M AM; Brueffer, Christian C; Gladchuk, Sergii S; Chen, Yilun Y; Vallon-Christersson, Johan J; Hegardt, Cecilia C; Häkkinen, Jari J; Rydén, Lisa L; Malmberg, Martin M; Larsson, Christer C; Gruvberger-Saal, Sofia K SK; Ehinger, Anna A; Loman, Niklas N; Borg, Åke Å; Saal, Lao H LH

Publication Date: 2021-04

Variant appearance in text: ESR1: L536R

PubMed Link: 33937624

Variant Present in the following documents:

• Main text

View BVdb publication page

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Significant impact of circulating tumour DNA mutations on survival in metastatic breast cancer patients.

Scientific Reports

Muendlein, Axel A; Geiger, Kathrin K; Gaenger, Stella S; Dechow, Tobias T; Nonnenbroich, Christoph C; Leiherer, Andreas A; Drexel, Heinz H; Gaumann, Andreas A; Jagla, Wolfgang W; Winder, Thomas T; Mayer, Frank F; Decker, Thomas T

Publication Date: 2021-03-24

Variant appearance in text: ESR1: 1607T>G; Leu536Arg

PubMed Link: 33762647

Variant Present in the following documents:

• 41598_2021_86238_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Molecular Biomarkers for Contemporary Therapies in Hormone Receptor-Positive Breast Cancer.

Genes

Freelander, Allegra A; Brown, Lauren J LJ; Parker, Andrew A; Segara, Davendra D; Portman, Neil N; Lau, Brandon B; Lim, Elgene E

Publication Date: 2021-02-17

Variant appearance in text: ESR1: Leu536Arg

PubMed Link: 33671468

Variant Present in the following documents:

• Main text
• genes-12-00285.pdf

View BVdb publication page

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ESR1 NAPA Assay: Development and Analytical Validation of a Highly Sensitive and Specific Blood-Based Assay for the Detection of ESR1 Mutations in Liquid Biopsies.

Cancers

Stergiopoulou, Dimitra D; Markou, Athina A; Tzanikou, Eleni E; Ladas, Ioannis I; Makrigiorgos, G Mike GM; Georgoulias, Vassilis V; Lianidou, Evi E

Publication Date: 2021-02-01

Variant appearance in text: ESR1: L536R

PubMed Link: 33535614

Variant Present in the following documents:

• Main text

View BVdb publication page

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A Closer Look at Estrogen Receptor Mutations in Breast Cancer and Their Implications for Estrogen and Antiestrogen Responses.

International Journal Of Molecular Sciences

Clusan, Léa L; Le Goff, Pascale P; Flouriot, Gilles G; Pakdel, Farzad F

Publication Date: 2021-01-13

Variant appearance in text: ESR1: L536R

PubMed Link: 33451133

Variant Present in the following documents:

• Main text
• ijms-22-00756.pdf

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: ESR1: 1607T>G; L536R

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
• 41467_2020_20162_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer.

Cancer Medicine

Sivapiragasam, Abirami A; Ashok Kumar, Prashanth P; Sokol, Ethan S ES; Albacker, Lee A LA; Killian, Jonathan K JK; Ramkissoon, Shakti H SH; Huang, Richard S P RSP; Severson, Eric A EA; Brown, Charlotte A CA; Danziger, Natalie N; McGregor, Kimberly K; Ross, Jeffrey S JS

Publication Date: 2021-01

Variant appearance in text: ESR1: L536R

PubMed Link: 33314633

Variant Present in the following documents:

• CAM4-10-53-s002.xlsx, sheet 1
• CAM4-10-53-s003.xlsx, sheet 1

View BVdb publication page

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Molecular landscape and efficacy of HER2-targeted therapy in patients with HER2-mutated metastatic breast cancer.

Npj Breast Cancer

Yi, Zongbi Z; Rong, Guohua G; Guan, Yanfang Y; Li, Jin J; Chang, Lianpeng L; Li, Hui H; Liu, Binliang B; Wang, Wenna W; Guan, Xiuwen X; Ouyang, Quchang Q; Li, Lixi L; Zhai, Jingtong J; Li, Chunxiao C; Li, Lifeng L; Xia, Xuefeng X; Yang, Ling L; Qian, Haili H; Yi, Xin X; Xu, Binghe B; Ma, Fei F

Publication Date: 2020

Variant appearance in text: ESR1: 1607T>G; L536R

PubMed Link: 33145402

Variant Present in the following documents:

• 41523_2020_201_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports

Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O

Publication Date: 2020-10-13

Variant appearance in text: rs1057519717

PubMed Link: 33051506

Variant Present in the following documents:

• 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Circulating tumour DNA in metastatic breast cancer to guide clinical trial enrolment and precision oncology: A cohort study.

Plos Medicine

Zivanovic Bujak, Andjelija A; Weng, Chen-Fang CF; Silva, Maria João MJ; Yeung, Miriam M; Lo, Louisa L; Ftouni, Sarah S; Litchfield, Cassandra C; Ko, Yi-An YA; Kuykhoven, Keilly K; Van Geelen, Courtney C; Chandrashekar, Sushma S; Dawson, Mark A MA; Loi, Sherene S; Wong, Stephen Q SQ; Dawson, Sarah-Jane SJ

Publication Date: 2020-10

Variant appearance in text: ESR1: L536R

PubMed Link: 33001984

Variant Present in the following documents:

• pmed.1003363.s014.xlsx, sheet 1
• pmed.1003363.s012.xlsx, sheet 1
• pmed.1003363.s013.xlsx, sheet 1

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Circulating tumour DNA analysis to direct therapy in advanced breast cancer (plasmaMATCH): a multicentre, multicohort, phase 2a, platform trial.

The Lancet. Oncology

Turner, Nicholas C NC; Kingston, Belinda B; Kilburn, Lucy S LS; Kernaghan, Sarah S; Wardley, Andrew M AM; Macpherson, Iain R IR; Baird, Richard D RD; Roylance, Rebecca R; Stephens, Peter P; Oikonomidou, Olga O; Braybrooke, Jeremy P JP; Tuthill, Mark M; Abraham, Jacinta J; Winter, Matthew C MC; Bye, Hannah H; Hubank, Michael M; Gevensleben, Heidrun H; Cutts, Ros R; Snowdon, Claire C; Rea, Daniel D; Cameron, David D; Shaaban, Abeer A; Randle, Katrina K; Martin, Sue S; Wilkinson, Katie K; Moretti, Laura L; Bliss, Judith M JM; Ring, Alistair A

Publication Date: 2020-10

Variant appearance in text: ESR1: Leu536Arg

PubMed Link: 32919527

Variant Present in the following documents:

• mmc1.pdf
• main.pdf

View BVdb publication page

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Increased frequency of ESR1 mutation in metastatic breast cancer by dosing selective estrogen receptor modulator followed by aromatase inhibitor.

Oncology Letters

Takeshima, Kaoru K; Hayashida, Tetsu T; Maeda, Hinako H; Nakashoji, Ayako A; Yokoe, Takamichi T; Seki, Tomoko T; Takahashi, Maiko M; Kitagawa, Yuko Y

Publication Date: 2020-08

Variant appearance in text: ESR1: Leu536Arg

PubMed Link: 32724363

Variant Present in the following documents:

• Main text
• ol-20-02-1231.pdf

View BVdb publication page

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Advances in the Detection Technologies and Clinical Applications of Circulating Tumor DNA in Metastatic Breast Cancer.

Cancer Management And Research

Liao, Hao H; Li, Huiping H

Publication Date: 2020

Variant appearance in text: ESR1: L536R

PubMed Link: 32547192

Variant Present in the following documents:

• Main text
• cmar-12-3547.pdf

View BVdb publication page

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Risk of early progression according to circulating ESR1 mutation, CA-15.3 and cfDNA increases under first-line anti-aromatase treatment in metastatic breast cancer.

Breast Cancer Research : Bcr

Clatot, Florian F; Perdrix, Anne A; Beaussire, Ludivine L; Lequesne, Justine J; Lévy, Christelle C; Emile, George G; Bubenheim, Michael M; Lacaille, Sigrid S; Calbrix, Céline C; Augusto, Laetitia L; Guillemet, Cécile C; Alexandru, Cristina C; Fontanilles, Maxime M; Sefrioui, David D; Burel, Lucie L; Guénot, Sabine S; Richard, Doriane D; Sarafan-Vasseur, Nasrin N; Di Fiore, Frédéric F

Publication Date: 2020-05-28

Variant appearance in text: ESR1: L536R

PubMed Link: 32466779

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• 13058_2020_Article_1290.pdf

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Quantitative Evaluation of the Transcriptional Activity of Steroid Hormone Receptor Mutants and Variants Using a Single Vector With Two Reporters and a Receptor Expression Cassette.

Frontiers In Endocrinology

Ji, Huimin H; Li, Ying Y; Liu, Zhao Z; Tang, Min M; Zou, Lihui L; Su, Fei F; Zhang, Yaqun Y; Zhang, Junhua J; Li, Hexin H; Li, Lin L; Ai, Bin B; Ma, Jie J; Wang, Lunan L; Liu, Ming M; Xiao, Fei F

Publication Date: 2020

Variant appearance in text: ESR1: L536R

PubMed Link: 32296391

Variant Present in the following documents:

• fendo-11-00167.pdf

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OncoOmics approaches to reveal essential genes in breast cancer: a panoramic view from pathogenesis to precision medicine.

Scientific Reports

López-Cortés, Andrés A; Paz-Y-Miño, César C; Guerrero, Santiago S; Cabrera-Andrade, Alejandro A; Barigye, Stephen J SJ; Munteanu, Cristian R CR; González-Díaz, Humberto H; Pazos, Alejandro A; Pérez-Castillo, Yunierkis Y; Tejera, Eduardo E

Publication Date: 2020-03-24

Variant appearance in text: ESR1: L536R

PubMed Link: 32210335

Variant Present in the following documents:

• 41598_2020_62279_MOESM2_ESM.xlsx, sheet 33

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: ESR1: L536R

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

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Dynamics Insights Into the Gain of Flexibility by Helix-12 in ESR1 as a Mechanism of Resistance to Drugs in Breast Cancer Cell Lines.

Frontiers In Molecular Biosciences

Khan, Abbas A; Ashfaq-Ur-Rehman, ; Junaid, Muhammad M; Li, Cheng-Dong CD; Saleem, Shoaib S; Humayun, Fahad F; Shamas, Shazia S; Ali, Syed Shujait SS; Babar, Zainib Z; Wei, Dong-Qing DQ

Publication Date: 2019

Variant appearance in text: ESR1: L536R

PubMed Link: 32039233

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• fmolb-06-00159.pdf

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ESR1 mutations are frequent in newly diagnosed metastatic and loco-regional recurrence of endocrine-treated breast cancer and carry worse prognosis.

Breast Cancer Research : Bcr

Zundelevich, Adi A; Dadiani, Maya M; Kahana-Edwin, Smadar S; Itay, Amit A; Sella, Tal T; Gadot, Moran M; Cesarkas, Karen K; Farage-Barhom, Sarit S; Saar, Efrat Glick EG; Eyal, Eran E; Kol, Nitzan N; Pavlovski, Anya A; Balint-Lahat, Nora N; Dick-Necula, Daniela D; Barshack, Iris I; Kaufman, Bella B; Gal-Yam, Einav Nili EN

Publication Date: 2020-02-03

Variant appearance in text: ESR1: L536R

PubMed Link: 32014063

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