ESR1 c.1609T>A ;(p.Y537N)

Variant ID: 6-152419922-T-A

NM_000125.3(ESR1):c.1609T>A;(p.Y537N)

This variant was identified in 193 publications

View GRCh38 version.




Publications:


Molecular profiling of a real-world breast cancer cohort with genetically inferred ancestries reveals actionable tumor biology differences between European ancestry and African ancestry patient populations.

Breast Cancer Research : Bcr
Miyashita, Minoru M; Bell, Joshua S K JSK; Wenric, Stephane S; Karaesmen, Ezgi E; Rhead, Brooke B; Kase, Matthew M; Kaneva, Kristiyana K; De La Vega, Francisco M FM; Zheng, Yonglan Y; Yoshimatsu, Toshio F TF; Khramtsova, Galina G; Liu, Fang F; Zhao, Fangyuan F; Howard, Frederick M FM; Nanda, Rita R; Beaubier, Nike N; White, Kevin P KP; Huo, Dezheng D; Olopade, Olufunmilayo I OI
Publication Date: 2023-05-25

Variant appearance in text: ESR1: 1609T>A; Y537N
PubMed Link: 37231433
Variant Present in the following documents:
  • 13058_2023_1627_MOESM4_ESM.xlsx, sheet 2
View BVdb publication page



Estrogen Receptor Alpha Splice Variants, Post-Translational Modifications, and Their Physiological Functions.

Cells
Saito, Kenji K; Cui, Huxing H
Publication Date: 2023-03-14

Variant appearance in text: ESR1: Y537N
PubMed Link: 36980236
Variant Present in the following documents:
  • Main text
View BVdb publication page



Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery
Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI
Publication Date: 2023-03-02

Variant appearance in text: ESR1: Y537N
PubMed Link: 36862804
Variant Present in the following documents:
  • 1116.pdf
View BVdb publication page



Unusual phylogenetic tree and circulating actionable ESR1 mutations in an aggressive luminal/HER2-low breast cancer: Case report.

Frontiers In Oncology
Allegretti, Matteo M; Barberi, Vittoria V; Ercolani, Cristiana C; Vidiri, Antonello A; Giordani, Elena E; Ciliberto, Gennaro G; Giacomini, Patrizio P; Fabi, Alessandra A
Publication Date: 2022

Variant appearance in text: ESR1: Y537N
PubMed Link: 36713585
Variant Present in the following documents:
  • Main text
  • fonc-12-1050452.pdf
View BVdb publication page



Comprehensive liquid biopsy analysis as a tool for the early detection of minimal residual disease in breast cancer.

Scientific Reports
Stergiopoulou, Dimitra D; Markou, Athina A; Strati, Areti A; Zavridou, Martha M; Tzanikou, Eleni E; Mastoraki, Sophia S; Kallergi, Galatea G; Georgoulias, Vassilis V; Lianidou, Evi E
Publication Date: 2023-01-23

Variant appearance in text: ESR1: Y537N
PubMed Link: 36690653
Variant Present in the following documents:
  • Main text
  • 41598_2022_Article_25400.pdf
View BVdb publication page



The Clinical Utility of Droplet Digital PCR for Profiling Circulating Tumor DNA in Breast Cancer Patients.

Diagnostics (Basel, Switzerland)
Gezer, Ugur U; Bronkhorst, Abel J AJ; Holdenrieder, Stefan S
Publication Date: 2022-12-05

Variant appearance in text: ESR1: Y537N
PubMed Link: 36553049
Variant Present in the following documents:
  • Main text
  • diagnostics-12-03042.pdf
View BVdb publication page



Targeted Protein Degradation: Clinical Advances in the Field of Oncology.

International Journal Of Molecular Sciences
Salama, Abdelrahman K A A AKAA; Trkulja, Marija V MV; Casanova, Emilio E; Uras, Iris Z IZ
Publication Date: 2022-12-06

Variant appearance in text: ESR1: Y537N
PubMed Link: 36499765
Variant Present in the following documents:
  • Main text
View BVdb publication page



Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer.

Nature Communications
Sivakumar, Smruthy S; Jin, Dexter X DX; Tukachinsky, Hanna H; Murugesan, Karthikeyan K; McGregor, Kimberly K; Danziger, Natalie N; Pavlick, Dean D; Gjoerup, Ole O; Ross, Jeffrey S JS; Harmon, Robert R; Chung, Jon J; Decker, Brennan B; Dennis, Lucas L; Frampton, Garrett M GM; Molinero, Luciana L; Oesterreich, Steffi S; Venstrom, Jeffrey M JM; Oxnard, Geoffrey R GR; Hegde, Priti S PS; Sokol, Ethan S ES
Publication Date: 2022-12-05

Variant appearance in text: ESR1: Y537N
PubMed Link: 36470901
Variant Present in the following documents:
  • 41467_2022_35245_MOESM4_ESM.xlsx, sheet 17
  • 41467_2022_35245_MOESM4_ESM.xlsx, sheet 13
View BVdb publication page



Concordance Between Recommendations From Multidisciplinary Molecular Tumor Boards and Central Consensus for Cancer Treatment in Japan.

Jama Network Open
Naito, Yoichi Y; Sunami, Kuniko K; Kage, Hidenori H; Komine, Keigo K; Amano, Toraji T; Imai, Mitsuho M; Koyama, Takafumi T; Ennishi, Daisuke D; Kanai, Masashi M; Kenmotsu, Hirotsugu H; Maeda, Takahiro T; Morita, Sachi S; Sakai, Daisuke D; Watanabe, Kousuke K; Shirota, Hidekazu H; Kinoshita, Ichiro I; Yoshioka, Masashiro M; Mamesaya, Nobuaki N; Ito, Mamoru M; Kohsaka, Shinji S; Saigusa, Yusuke Y; Yamamoto, Kouji K; Hirata, Makoto M; Tsuchihara, Katsuya K; Yoshino, Takayuki T
Publication Date: 2022-12-01

Variant appearance in text: ESR1: Y537N
PubMed Link: 36469316
Variant Present in the following documents:
  • jamanetwopen-e2245081-s001.pdf
View BVdb publication page



Elacestrant demonstrates strong anti-estrogenic activity in PDX models of estrogen-receptor positive endocrine-resistant and fulvestrant-resistant breast cancer.

Npj Breast Cancer
Pancholi, Sunil S; Simigdala, Nikiana N; Ribas, Ricardo R; Schuster, Eugene E; Leal, Mariana Ferreira MF; Nikitorowicz-Buniak, Joanna J; Rega, Camilla C; Bihani, Teeru T; Patel, Hitisha H; Johnston, Stephen R SR; Dowsett, Mitch M; Martin, Lesley-Ann LA
Publication Date: 2022-11-29

Variant appearance in text: ESR1: Y537N
PubMed Link: 36446866
Variant Present in the following documents:
  • Main text
View BVdb publication page



The oral selective estrogen receptor degrader GDC-0810 (ARN-810) in postmenopausal women with hormone receptor-positive HER2-negative (HR + /HER2 -) advanced/metastatic breast cancer.

Breast Cancer Research And Treatment
Bardia, Aditya A; Mayer, Ingrid I; Winer, Eric E; Linden, Hannah M HM; Ma, Cynthia X CX; Parker, Barbara A BA; Bellet, Meritxell M; Arteaga, Carlos L CL; Cheeti, Sravanthi S; Gates, Mary M; Chang, Ching-Wei CW; Fredrickson, Jill J; Spoerke, Jill M JM; Moore, Heather M HM; Giltnane, Jennifer J; Friedman, Lori S LS; Chow Maneval, Edna E; Chan, Iris I; Jhaveri, Komal K
Publication Date: 2022-11-19

Variant appearance in text: ESR1: Y537N
PubMed Link: 36401732
Variant Present in the following documents:
  • 10549_2022_6797_MOESM1_ESM.pdf
View BVdb publication page



Genome engineering for estrogen receptor mutations reveals differential responses to anti-estrogens and new prognostic gene signatures for breast cancer.

Oncogene
Harrod, Alison A; Lai, Chun-Fui CF; Goldsbrough, Isabella I; Simmons, Georgia M GM; Oppermans, Natasha N; Santos, Daniela B DB; Győrffy, Balazs B; Allsopp, Rebecca C RC; Toghill, Bradley J BJ; Balachandran, Kirsty K; Lawson, Mandy M; Morrow, Christopher J CJ; Surakala, Manasa M; Carnevalli, Larissa S LS; Zhang, Pei P; Guttery, David S DS; Shaw, Jacqueline A JA; Coombes, R Charles RC; Buluwela, Lakjaya L; Ali, Simak S
Publication Date: 2022-10

Variant appearance in text: ESR1: Y537N
PubMed Link: 36198774
Variant Present in the following documents:
  • Main text
  • 41388_2022_2483_MOESM2_ESM.pdf
  • 41388_2022_Article_2483.pdf
  • 41388_2022_2483_MOESM1_ESM.pdf
View BVdb publication page



CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience
Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X
Publication Date: 2022-09-16

Variant appearance in text: ESR1: Y537N
PubMed Link: 36117989
Variant Present in the following documents:
  • mmc4.xlsx, sheet 1
View BVdb publication page



Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer.

British Journal Of Cancer
Fernandez-Garcia, Daniel D; Nteliopoulos, Georgios G; Hastings, Robert K RK; Rushton, Amelia A; Page, Karen K; Allsopp, Rebecca C RC; Ambasager, Bana B; Gleason, Kelly K; Guttery, David S DS; Ali, Simak S; Charles Coombes, R R; Shaw, Jacqueline A JA
Publication Date: 2022-11

Variant appearance in text: ESR1: Y537N
PubMed Link: 36088510
Variant Present in the following documents:
  • Main text
  • 41416_2022_1962_MOESM2_ESM.xlsx, sheet 4
  • 41416_2022_1962_MOESM2_ESM.xlsx, sheet 5
  • 41416_2022_Article_1962.pdf
View BVdb publication page



S6K1 amplification confers innate resistance to CDK4/6 inhibitors through activating c-Myc pathway in patients with estrogen receptor-positive breast cancer.

Molecular Cancer
Mo, Hongnan H; Liu, Xuefeng X; Xue, Yu Y; Chen, Hongyan H; Guo, Shichao S; Li, Zhangfu Z; Wang, Shuang S; Li, Caiming C; Han, Jiashu J; Fu, Ming M; Song, Yongmei Y; Li, Dan D; Ma, Fei F
Publication Date: 2022-08-30

Variant appearance in text: ESR1: 1609T>A; Y537N
PubMed Link: 36042494
Variant Present in the following documents:
  • 12943_2022_1642_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Integrative genomic and transcriptomic analyses illuminate the ontology of HER2-low breast carcinomas.

Genome Medicine
Berrino, Enrico E; Annaratone, Laura L; Bellomo, Sara Erika SE; Ferrero, Giulio G; Gagliardi, Amedeo A; Bragoni, Alberto A; Grassini, Dora D; Guarrera, Simonetta S; Parlato, Caterina C; Casorzo, Laura L; Panero, Mara M; Sarotto, Ivana I; Giordano, Silvia S; Cereda, Matteo M; Montemurro, Filippo F; Ponzone, Riccardo R; Crosetto, Nicola N; Naccarati, Alessio A; Sapino, Anna A; Marchiò, Caterina C
Publication Date: 2022-08-29

Variant appearance in text: ESR1: Y537N
PubMed Link: 36038884
Variant Present in the following documents:
  • 13073_2022_1104_MOESM8_ESM.xlsx, sheet 1
View BVdb publication page



Prognostic value of baseline genetic features and newly identified TP53 mutations in advanced breast cancer.

Molecular Oncology
Zhang, Lanxin L; Sun, Siwen S; Zhao, Xiaotian X; Liu, Jingwen J; Xu, Yang Y; Xu, Lingzhi L; Song, Chen C; Li, Na N; Yu, Jing J; Zhao, Shanshan S; Yu, Peiyao P; Fang, Fengqi F; Xie, Jiping J; Ji, Xuening X; Yu, Ruoying R; Ou, Qiuxiang Q; Zhao, Zuowei Z; Li, Man M
Publication Date: 2022-10

Variant appearance in text: ESR1: 1609T>A; Y537N
PubMed Link: 35971249
Variant Present in the following documents:
  • MOL2-16-3689-s005.xlsx, sheet 1
View BVdb publication page



The circulating tumor DNA (ctDNA) alteration level predicts therapeutic response in metastatic breast cancer: Novel prognostic indexes based on ctDNA.

Breast (Edinburgh, Scotland)
Liu, Binliang B; Hu, Zheyu Z; Ran, Jialu J; Xie, Ning N; Tian, Can C; Tang, Yu Y; Ouyang, Quchang Q
Publication Date: 2022-10

Variant appearance in text: ESR1: Y537N
PubMed Link: 35926241
Variant Present in the following documents:
  • mmc1.xlsx, sheet 1
View BVdb publication page



Predictors of fulvestrant long-term benefit in hormone receptor-positive/HER2 negative advanced breast cancer.

Scientific Reports
Torrisi, Rosalba R; Vaira, Valentina V; Giordano, Laura L; Destro, Annarita A; Basilico, Vera V; Mazzara, Saveria S; Salvini, Piermario P; Gaudioso, Gabriella G; Fernandes, Bethania B; Rudini, Noemi N; Masci, Giovanna G; Santoro, Armando A
Publication Date: 2022-07-27

Variant appearance in text: ESR1: Y537N
PubMed Link: 35896637
Variant Present in the following documents:
  • 41598_2022_16409_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



AMEERA-1 phase 1/2 study of amcenestrant, SAR439859, in postmenopausal women with ER-positive/HER2-negative advanced breast cancer.

Nature Communications
Bardia, Aditya A; Chandarlapaty, Sarat S; Linden, Hannah M HM; Ulaner, Gary A GA; Gosselin, Alice A; Cartot-Cotton, Sylvaine S; Cohen, Patrick P; Doroumian, Séverine S; Paux, Gautier G; Celanovic, Marina M; Pelekanou, Vasiliki V; Ming, Jeffrey E JE; Ternès, Nils N; Bouaboula, Monsif M; Lee, Joon Sang JS; Bauchet, Anne-Laure AL; Campone, Mario M
Publication Date: 2022-07-15

Variant appearance in text: ESR1: Y537N
PubMed Link: 35840573
Variant Present in the following documents:
  • Main text
  • 41467_2022_Article_31668.pdf
View BVdb publication page



AACR Project GENIE: 100,000 Cases and Beyond.

Cancer Discovery
Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,
Publication Date: 2022-09-02

Variant appearance in text: ESR1: Y537N
PubMed Link: 35819403
Variant Present in the following documents:
  • cd-21-1547_supplementary_table_1_suppst1.xlsx, sheet 1
View BVdb publication page



Interrogating breast cancer heterogeneity using single and pooled circulating tumor cell analysis.

Npj Breast Cancer
Rothé, Françoise F; Venet, David D; Peeters, Dieter D; Rouas, Ghizlane G; Rediti, Mattia M; Smeets, Dominiek D; Dupont, Floriane F; Campbell, Peter P; Lambrechts, Diether D; Dirix, Luc L; Sotiriou, Christos C; Ignatiadis, Michail M
Publication Date: 2022-07-05

Variant appearance in text: ESR1: Y537N
PubMed Link: 35790747
Variant Present in the following documents:
  • Main text
  • 41523_2022_Article_445.pdf
View BVdb publication page



Estrogen Receptor-Regulated Gene Signatures in Invasive Breast Cancer Cells and Aggressive Breast Tumors.

Cancers
Smart, Emily E; Semina, Svetlana E SE; Alejo, Luis H LH; Kansara, Nidhi S NS; Frasor, Jonna J
Publication Date: 2022-06-09

Variant appearance in text: ESR1: Y537N
PubMed Link: 35740514
Variant Present in the following documents:
  • Main text
  • cancers-14-02848.pdf
View BVdb publication page



Decoding the Therapeutic Implications of the ERα Stability and Subcellular Distribution in Breast Cancer.

Frontiers In Endocrinology
Tecalco-Cruz, Angeles C AC; Macías-Silva, Marina M; Ramírez-Jarquín, Josué Orlando JO; Ramírez-Jarquín, Uri Nimrod UN
Publication Date: 2022

Variant appearance in text: ESR1: Y537N
PubMed Link: 35498431
Variant Present in the following documents:
  • Main text
  • fendo-13-867448.pdf
View BVdb publication page



Global Increase in Breast Cancer Incidence: Risk Factors and Preventive Measures.

Biomed Research International
Kashyap, Dharambir D; Pal, Deeksha D; Sharma, Riya R; Garg, Vivek Kumar VK; Goel, Neelam N; Koundal, Deepika D; Zaguia, Atef A; Koundal, Shubham S; Belay, Assaye A
Publication Date: 2022

Variant appearance in text: ESR1: Tyr537Asn
PubMed Link: 35480139
Variant Present in the following documents:
  • BMRI2022-9605439.pdf
View BVdb publication page



Estrogen Receptor Bio-Activities Determine Clinical Endocrine Treatment Options in Estrogen Receptor-Positive Breast Cancer.

Technology In Cancer Research & Treatment
Xia, Song S; Lin, Qiong Q
Publication Date: 2022

Variant appearance in text: ESR1: Y537N
PubMed Link: 35450488
Variant Present in the following documents:
  • Main text
  • 10.1177_15330338221090351.pdf
View BVdb publication page



ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation.

Nature Communications
Li, Zheqi Z; McGinn, Olivia O; Wu, Yang Y; Bahreini, Amir A; Priedigkeit, Nolan M NM; Ding, Kai K; Onkar, Sayali S; Lampenfeld, Caleb C; Sartorius, Carol A CA; Miller, Lori L; Rosenzweig, Margaret M; Cohen, Ofir O; Wagle, Nikhil N; Richer, Jennifer K JK; Muller, William J WJ; Buluwela, Laki L; Ali, Simak S; Bruno, Tullia C TC; Vignali, Dario A A DAA; Fang, Yusi Y; Zhu, Li L; Tseng, George C GC; Gertz, Jason J; Atkinson, Jennifer M JM; Lee, Adrian V AV; Oesterreich, Steffi S
Publication Date: 2022-04-19

Variant appearance in text: ESR1: Y537N
PubMed Link: 35440136
Variant Present in the following documents:
  • 41467_2022_29498_MOESM3_ESM.pdf
  • 41467_2022_29498_MOESM1_ESM.pdf
View BVdb publication page



Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.

Cancer Medicine
Liu, Binliang B; Yi, Zongbi Z; Guan, Yanfang Y; Ouyang, Quchang Q; Li, Chunxiao C; Guan, Xiuwen X; Lv, Dan D; Li, Lixi L; Zhai, Jingtong J; Qian, Haili H; Xu, Binghe B; Ma, Fei F; Zeng, Yixin Y
Publication Date: 2022-07

Variant appearance in text: ESR1: 1609T>A; Y537N
PubMed Link: 35393784
Variant Present in the following documents:
  • CAM4-11-2767-s001.xlsx, sheet 1
View BVdb publication page



Targeted next generation sequencing of circulating tumor DNA provides prognostic information for management in breast cancer patients.

Annals Of Translational Medicine
Shim, Hyoeun H; Kwon, Min Jeong MJ; Park, In Hae IH; Kim, Min Kyeong MK; Cho, Eun-Hae EH; Lee, Junnam J; Lee, Seung-Tae ST; Sim, Sung Hoon SH; Lee, Keun Seok KS; Kim, Yun-Hee YH; Kim, Seok-Ki SK; Lee, Eun Sook ES; Kong, Sun-Young SY
Publication Date: 2022-01

Variant appearance in text: ESR1: Y537N
PubMed Link: 35282050
Variant Present in the following documents:
  • Main text
  • atm-10-02-28.pdf
View BVdb publication page



A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology.

Nature Cancer
Guillen, Katrin P KP; Fujita, Maihi M; Butterfield, Andrew J AJ; Scherer, Sandra D SD; Bailey, Matthew H MH; Chu, Zhengtao Z; DeRose, Yoko S YS; Zhao, Ling L; Cortes-Sanchez, Emilio E; Yang, Chieh-Hsiang CH; Toner, Jennifer J; Wang, Guoying G; Qiao, Yi Y; Huang, Xiaomeng X; Greenland, Jeffery A JA; Vahrenkamp, Jeffery M JM; Lum, David H DH; Factor, Rachel E RE; Nelson, Edward W EW; Matsen, Cindy B CB; Poretta, Jane M JM; Rosenthal, Regina R; Beck, Anna C AC; Buys, Saundra S SS; Vaklavas, Christos C; Ward, John H JH; Jensen, Randy L RL; Jones, Kevin B KB; Li, Zheqi Z; Oesterreich, Steffi S; Dobrolecki, Lacey E LE; Pathi, Satya S SS; Woo, Xing Yi XY; Berrett, Kristofer C KC; Wadsworth, Mark E ME; Chuang, Jeffrey H JH; Lewis, Michael T MT; Marth, Gabor T GT; Gertz, Jason J; Varley, Katherine E KE; Welm, Bryan E BE; Welm, Alana L AL
Publication Date: 2022-02

Variant appearance in text: ESR1: Y537N
PubMed Link: 35221336
Variant Present in the following documents:
  • Main text
  • 43018_2022_Article_337.pdf
View BVdb publication page



The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer
Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J
Publication Date: 2022-02

Variant appearance in text: ESR1: Tyr537Asn
PubMed Link: 35221333
Variant Present in the following documents:
  • 43018_2022_332_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Disease characterization in liquid biopsy from HER2-mutated, non-amplified metastatic breast cancer patients treated with neratinib.

Npj Breast Cancer
Shishido, Stephanie N SN; Masson, Rahul R; Xu, Liya L; Welter, Lisa L; Prabakar, Rishvanth Kaliappan RK; D' Souza, Anishka A; Spicer, Darcy D; Kang, Irene I; Jayachandran, Priya P; Hicks, James J; Lu, Janice J; Kuhn, Peter P
Publication Date: 2022-02-18

Variant appearance in text: ESR1: Y537N
PubMed Link: 35181666
Variant Present in the following documents:
  • 41523_2022_390_MOESM1_ESM.pdf
  • 41523_2022_Article_390.pdf
View BVdb publication page



Intratumor genetic heterogeneity and clonal evolution to decode endometrial cancer progression.

Oncogene
Mota, Alba A; Oltra, Sara S SS; Selenica, Pier P; Moiola, Cristian P CP; Casas-Arozamena, Carlos C; López-Gil, Carlos C; Diaz, Eva E; Gatius, Sonia S; Ruiz-Miro, María M; Calvo, Ana A; Rojo-Sebastián, Alejandro A; Hurtado, Pablo P; Piñeiro, Roberto R; Colas, Eva E; Gil-Moreno, Antonio A; Reis-Filho, Jorge S JS; Muinelo-Romay, Laura L; Abal, Miguel M; Matias-Guiu, Xavier X; Weigelt, Britta B; Moreno-Bueno, Gema G
Publication Date: 2022-03

Variant appearance in text: ESR1: Y537N
PubMed Link: 35145232
Variant Present in the following documents:
  • 41388_2022_2221_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Role of ctDNA in Breast Cancer.

Cancers
Sant, Marta M; Bernat-Peguera, Adrià A; Felip, Eudald E; Margelí, Mireia M
Publication Date: 2022-01-09

Variant appearance in text: ESR1: Y537N
PubMed Link: 35053474
Variant Present in the following documents:
  • Main text
  • cancers-14-00310.pdf
View BVdb publication page



Role of ctDNA in Breast Cancer.

Cancers
Sant, Marta M; Bernat-Peguera, Adrià A; Felip, Eudald E; Margelí, Mireia M
Publication Date: 2022-01-09

Variant appearance in text: ESR1: Y537N
PubMed Link: 35053474
Variant Present in the following documents:
  • Main text
  • cancers-14-00310.pdf
View BVdb publication page



Circulating Tumor DNA Profiling From Breast Cancer Screening Through to Metastatic Disease.

Jco Precision Oncology
Page, Karen K; Martinson, Luke J LJ; Fernandez-Garcia, Daniel D; Hills, Allison A; Gleason, Kelly L T KLT; Gray, Molly C MC; Rushton, Amelia J AJ; Nteliopoulos, Georgios G; Hastings, Robert K RK; Goddard, Kate K; Ions, Charlotte C; Parmar, Vilas V; Primrose, Lindsay L; Openshaw, Mark R MR; Guttery, David S DS; Palmieri, Carlo C; Ali, Simak S; Stebbing, Justin J; Coombes, R Charles RC; Shaw, Jacqueline A JA
Publication Date: 2021

Variant appearance in text: ESR1: Y537N
PubMed Link: 34849446
Variant Present in the following documents:
  • po-5-po.20.00522.pdf
View BVdb publication page



Resistance Mechanisms to Combined CDK4/6 Inhibitors and Endocrine Therapy in ER+/HER2- Advanced Breast Cancer: Biomarkers and Potential Novel Treatment Strategies.

Cancers
Al-Qasem, Abeer J AJ; Alves, Carla L CL; Ditzel, Henrik J HJ
Publication Date: 2021-10-27

Variant appearance in text: ESR1: Y537N
PubMed Link: 34771560
Variant Present in the following documents:
  • Main text
View BVdb publication page



An immune-humanized patient-derived xenograft model of estrogen-independent, hormone receptor positive metastatic breast cancer.

Breast Cancer Research : Bcr
Scherer, Sandra D SD; Riggio, Alessandra I AI; Haroun, Fadi F; DeRose, Yoko S YS; Ekiz, H Atakan HA; Fujita, Maihi M; Toner, Jennifer J; Zhao, Ling L; Li, Zheqi Z; Oesterreich, Steffi S; Samatar, Ahmed A AA; Welm, Alana L AL
Publication Date: 2021-10-30

Variant appearance in text: ESR1: Y537N
PubMed Link: 34717714
Variant Present in the following documents:
  • Main text
  • 13058_2021_Article_1476.pdf
View BVdb publication page



Transcriptional Reprogramming Differentiates Active from Inactive ESR1 Fusions in Endocrine Therapy-Refractory Metastatic Breast Cancer.

Cancer Research
Gou, Xuxu X; Anurag, Meenakshi M; Lei, Jonathan T JT; Kim, Beom-Jun BJ; Singh, Purba P; Seker, Sinem S; Fandino, Diana D; Han, Airi A; Rehman, Saif S; Hu, Jianhong J; Korchina, Viktoriya V; Doddapaneni, Harshavardhan H; Dobrolecki, Lacey E LE; Mitsiades, Nicholas N; Lewis, Michael T MT; Welm, Alana L AL; Li, Shunqiang S; Lee, Adrian V AV; Robinson, Dan R DR; Foulds, Charles E CE; Ellis, Matthew J MJ
Publication Date: 2021-12-15

Variant appearance in text: ESR1: Y537N
PubMed Link: 34711608
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Prolactin and endocrine therapy resistance in breast cancer: The next potential hope for breast cancer treatment.

Journal Of Cellular And Molecular Medicine
Li, Yuan Y; Kong, Xiangyi X; Xuan, Lixue L; Wang, Zhongzhao Z; Huang, Yen-Hua YH
Publication Date: 2021-11

Variant appearance in text: ESR1: Y537N
PubMed Link: 34651424
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  • JCMM-25-10327.pdf
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Prolactin and endocrine therapy resistance in breast cancer: The next potential hope for breast cancer treatment.

Journal Of Cellular And Molecular Medicine
Li, Yuan Y; Kong, Xiangyi X; Xuan, Lixue L; Wang, Zhongzhao Z; Huang, Yen-Hua YH
Publication Date: 2021-11

Variant appearance in text: ESR1: Y537N
PubMed Link: 34651424
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Profiling Receptor Tyrosine Kinase Fusions in Chinese Breast Cancers.

Frontiers In Oncology
Tao, Zhonghua Z; Liu, Jianxia J; Li, Ting T; Xu, Hong H; Chen, Kai K; Zhang, Jian J; Zhou, Hao H; Sun, Jie J; Han, Jinming J; Guo, Zhaoji Z; Yang, Hua H; Cao, Wen-Ming WM; Hu, Xichun X
Publication Date: 2021

Variant appearance in text: ESR1: 1609T>A; Y537N
PubMed Link: 34650924
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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: ESR1: Y537N
PubMed Link: 34630336
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FDG positron emission tomography imaging and ctDNA detection as an early dynamic biomarker of everolimus efficacy in advanced luminal breast cancer.

Npj Breast Cancer
Gombos, Andrea A; Venet, David D; Ameye, Lieveke L; Vuylsteke, Peter P; Neven, Patrick P; Richard, Vincent V; Duhoux, Francois P FP; Laes, Jean-Francois JF; Rothe, Françoise F; Sotiriou, Christos C; Paesmans, Marianne M; Awada, Ahmad A; Guiot, Thomas T; Flamen, Patrick P; Piccart-Gebhart, Martine M; Ignatiadis, Michail M; Gebhart, Géraldine G
Publication Date: 2021-09-21

Variant appearance in text: ESR1: 1609T>A; Y537N
PubMed Link: 34548493
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