ESR1 c.1626G>C ;(p.E542D)

Variant ID: 6-152419939-G-C

NM_000125.3(ESR1):c.1626G>C;(p.E542D)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Phase I Study of Elacestrant (RAD1901), a Novel Selective Estrogen Receptor Degrader, in ER-Positive, HER2-Negative Advanced Breast Cancer.

Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology
Bardia, Aditya A; Kaklamani, Virginia V; Wilks, Sharon S; Weise, Amy A; Richards, Donald D; Harb, Wael W; Osborne, Cynthia C; Wesolowski, Robert R; Karuturi, Meghan M; Conkling, Paul P; Bagley, Rebecca G RG; Wang, Yamei Y; Conlan, Maureen G MG; Kabos, Peter P
Publication Date: 2021-04-20

Variant appearance in text: ESR1: E542D
PubMed Link: 33513026
Variant Present in the following documents:
  • Main text
  • jco-39-1360.pdf
View BVdb publication page



Increased frequency of ESR1 mutation in metastatic breast cancer by dosing selective estrogen receptor modulator followed by aromatase inhibitor.

Oncology Letters
Takeshima, Kaoru K; Hayashida, Tetsu T; Maeda, Hinako H; Nakashoji, Ayako A; Yokoe, Takamichi T; Seki, Tomoko T; Takahashi, Maiko M; Kitagawa, Yuko Y
Publication Date: 2020-08

Variant appearance in text: ESR1: Glu542Asp
PubMed Link: 32724363
Variant Present in the following documents:
  • Main text
  • ol-20-02-1231.pdf
View BVdb publication page



ESR1 mutations in breast cancer.

Cancer
Dustin, Derek D; Gu, Guowei G; Fuqua, Suzanne A W SAW
Publication Date: 2019-11-01

Variant appearance in text: ESR1: E542D
PubMed Link: 31318440
Variant Present in the following documents:
  • Main text
View BVdb publication page



Hybrid capture-based genomic profiling of circulating tumor DNA from patients with estrogen receptor-positive metastatic breast cancer.

Annals Of Oncology : Official Journal Of The European Society For Medical Oncology
Chung, J H JH; Pavlick, D D; Hartmaier, R R; Schrock, A B AB; Young, L L; Forcier, B B; Ye, P P; Levin, M K MK; Goldberg, M M; Burris, H H; Gay, L M LM; Hoffman, A D AD; Stephens, P J PJ; Frampton, G M GM; Lipson, D M DM; Nguyen, D M DM; Ganesan, S S; Park, B H BH; Vahdat, L T LT; Leyland-Jones, B B; Mughal, T I TI; Pusztai, L L; O'Shaughnessy, J J; Miller, V A VA; Ross, J S JS; Ali, S M SM
Publication Date: 2017-11-01

Variant appearance in text: ESR1: E542D
PubMed Link: 28945887
Variant Present in the following documents:
  • mdx490.pdf
View BVdb publication page