Publications:

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Molecular Imaging of Opioid and Dopamine Systems: Insights Into the Pharmacogenetics of Opioid Use Disorders.

Frontiers In Psychiatry

Burns, Jamie A JA; Kroll, Danielle S DS; Feldman, Dana E DE; Kure Liu, Christopher C; Manza, Peter P; Wiers, Corinde E CE; Volkow, Nora D ND; Wang, Gene-Jack GJ

Publication Date: 2019

Variant appearance in text: rs3778151

PubMed Link: 31620026

Variant Present in the following documents:

• Main text
• fpsyt-10-00626.pdf

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The Influence of Genetic Variation on Social Disposition, Romantic Relationships and Social Networks: a Replication Study.

Adaptive Human Behavior And Physiology

Pearce, Eiluned E; Wlodarski, Rafael R; Machin, Anna A; Dunbar, Robin I M RIM

Publication Date: 2018

Variant appearance in text: rs3778151

PubMed Link: 30393594

Variant Present in the following documents:

• Main text
• 40750_2018_Article_101.pdf

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Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes.

The Pharmacogenomics Journal

Choi, Jihoon J; Tantisira, Kelan G KG; Duan, Qing Ling QL

Publication Date: 2019-04

Variant appearance in text: rs3778151

PubMed Link: 30214008

Variant Present in the following documents:

• NIHMS1503453-supplement-3.xlsx, sheet 1

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The μ-opioid receptor nonsynonymous variant 118A>G is associated with prolonged abstinence from heroin without agonist treatment.

Pharmacogenomics

Levran, Orna O; Peles, Einat E; Randesi, Matthew M; da Rosa, Joel Correa JC; Adelson, Miriam M; Kreek, Mary Jeanne MJ

Publication Date: 2017-10

Variant appearance in text: rs3778151

PubMed Link: 28976288

Variant Present in the following documents:

• Main text

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Variation in the β-endorphin, oxytocin, and dopamine receptor genes is associated with different dimensions of human sociality.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Pearce, Eiluned E; Wlodarski, Rafael R; Machin, Anna A; Dunbar, Robin I M RIM

Publication Date: 2017-05-16

Variant appearance in text: rs3778151

PubMed Link: 28461468

Variant Present in the following documents:

• Main text

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A review of pharmacogenetic studies of substance-related disorders.

Drug And Alcohol Dependence

Jones, Jermaine D JD; Comer, Sandra D SD

Publication Date: 2015-07-01

Variant appearance in text: rs3778151

PubMed Link: 25819021

Variant Present in the following documents:

• Main text

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Cis-Expression Quantitative Trait Loci Mapping Reveals Replicable Associations with Heroin Addiction in OPRM1.

Biological Psychiatry

Hancock, Dana B DB; Levy, Joshua L JL; Gaddis, Nathan C NC; Glasheen, Cristie C; Saccone, Nancy L NL; Page, Grier P GP; Hulse, Gary K GK; Wildenauer, Dieter D; Kelty, Erin A EA; Schwab, Sibylle G SG; Degenhardt, Louisa L; Martin, Nicholas G NG; Montgomery, Grant W GW; Attia, John J; Holliday, Elizabeth G EG; McEvoy, Mark M; Scott, Rodney J RJ; Bierut, Laura J LJ; Nelson, Elliot C EC; Kral, Alex H AH; Johnson, Eric O EO

Publication Date: 2015-10-01

Variant appearance in text: rs3778151

PubMed Link: 25744370

Variant Present in the following documents:

• Main text

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Association of polymorphisms in pharmacogenetic candidate genes (OPRD1, GAL, ABCB1, OPRM1) with opioid dependence in European population: a case-control study.

Plos One

Beer, Beate B; Erb, Robert R; Pavlic, Marion M; Ulmer, Hanno H; Giacomuzzi, Salvatore S; Riemer, Yvonne Y; Oberacher, Herbert H

Publication Date: 2013

Variant appearance in text: rs3778151

PubMed Link: 24086514

Variant Present in the following documents:

• Main text

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Mu opioid receptor (OPRM1) as a predictor of treatment outcome in opiate-dependent individuals of Arab descent.

Pharmacogenomics And Personalized Medicine

Al-Eitan, Laith N LN; Jaradat, Saied A SA; Su, Steve Ys SY; Tay, Guan K GK; Hulse, Gary K GK

Publication Date: 2012

Variant appearance in text: rs3778151

PubMed Link: 23226066

Variant Present in the following documents:

• Main text
• pgpm-5-099.pdf

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κ-opioid receptor/dynorphin system: genetic and pharmacotherapeutic implications for addiction.

Trends In Neurosciences

Butelman, Eduardo R ER; Yuferov, Vadim V; Kreek, Mary Jeanne MJ

Publication Date: 2012-10

Variant appearance in text: rs3778151

PubMed Link: 22709632

Variant Present in the following documents:

• Main text

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The genetics of the opioid system and specific drug addictions.

Human Genetics

Levran, Orna O; Yuferov, Vadim V; Kreek, Mary Jeanne MJ

Publication Date: 2012-06

Variant appearance in text: rs3778151

PubMed Link: 22547174

Variant Present in the following documents:

• Main text

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Common and specific liability to addiction: approaches to association studies of opioid addiction.

Drug And Alcohol Dependence

Nielsen, David A DA; Kreek, Mary Jeanne MJ

Publication Date: 2012-06

Variant appearance in text: rs3778151

PubMed Link: 22542464

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• Main text

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Association of OPRD1 polymorphisms with heroin dependence in a large case-control series.

Addiction Biology

Nelson, Elliot C EC; Lynskey, Michael T MT; Heath, Andrew C AC; Wray, Naomi N; Agrawal, Arpana A; Shand, Fiona L FL; Henders, Anjali K AK; Wallace, Leanne L; Todorov, Alexandre A AA; Schrage, Andrew J AJ; Madden, Pamela A F PA; Degenhardt, Louisa L; Martin, Nicholas G NG; Montgomery, Grant W GW

Publication Date: 2014-01

Variant appearance in text: rs3778151

PubMed Link: 22500942

Variant Present in the following documents:

• Main text

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Association of polymorphisms of the mu opioid receptor gene with the severity of HIV infection and response to HIV treatment.

The Journal Of Infectious Diseases

Proudnikov, Dmitri D; Randesi, Matthew M; Levran, Orna O; Crystal, Howard H; Dorn, Magdalena M; Ott, Jurg J; Ho, Ann A; Kreek, Mary Jeanne MJ

Publication Date: 2012-06

Variant appearance in text: rs3778151

PubMed Link: 22457278

Variant Present in the following documents:

• Main text

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Molecular mechanisms of opioid receptor-dependent signaling and behavior.

Anesthesiology

Al-Hasani, Ream R; Bruchas, Michael R MR

Publication Date: 2011-12

Variant appearance in text: rs3778151

PubMed Link: 22020140

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• Main text

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Different phenotypic and genotypic presentations in alcohol dependence: age at onset matters.

Journal Of Studies On Alcohol And Drugs

Chen, Yu-Chu YC; Prescott, Carol A CA; Walsh, Dermot D; Patterson, Diana G DG; Riley, Brien P BP; Kendler, Kenneth S KS; Kuo, Po-Hsiu PH

Publication Date: 2011-09

Variant appearance in text: rs3778151

PubMed Link: 21906503

Variant Present in the following documents:

• Main text

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Gender-stratified gene and gene-treatment interactions in smoking cessation.

The Pharmacogenomics Journal

Lee, W W; Bergen, A W AW; Swan, G E GE; Li, D D; Liu, J J; Thomas, P P; Tyndale, R F RF; Benowitz, N L NL; Lerman, C C; Conti, D V DV

Publication Date: 2012-12

Variant appearance in text: rs3778151

PubMed Link: 21808284

Variant Present in the following documents:

• NIHMS305090-supplement-3.pdf

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No evidence of association between 118A>G OPRM1 polymorphism and heroin dependence in a large Bulgarian case-control sample.

Drug And Alcohol Dependence

Nikolov, Momchil A MA; Beltcheva, Olga O; Galabova, Antoaneta A; Ljubenova, Anna A; Jankova, Elena E; Gergov, Galin G; Russev, Atanas A AA; Lynskey, Michael T MT; Nelson, Elliot C EC; Nesheva, Eleonora E; Krasteva, Dorita D; Lazarov, Philip P; Mitev, Vanio I VI; Kremensky, Ivo M IM; Kaneva, Radka P RP; Todorov, Alexandre A AA

Publication Date: 2011-08-01

Variant appearance in text: rs3778151

PubMed Link: 21277709

Variant Present in the following documents:

• Main text

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Haplotype block structure of the genomic region of the mu opioid receptor gene.

Journal Of Human Genetics

Levran, Orna O; Awolesi, Olaoluwakitan O; Linzy, Shirley S; Adelson, Miriam M; Kreek, Mary Jeanne MJ

Publication Date: 2011-02

Variant appearance in text: rs3778151

PubMed Link: 21160491

Variant Present in the following documents:

• Main text
• nihms-252057.pdf

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Neurotransmitter and neuromodulator genes associated with a history of depressive symptoms in individuals with alcohol dependence.

Alcoholism, Clinical And Experimental Research

Kertes, Darlene A DA; Kalsi, Gursharan G; Prescott, Carol A CA; Kuo, Po-Hsiu PH; Patterson, Diana G DG; Walsh, Dermot D; Kendler, Kenneth S KS; Riley, Brien P BP

Publication Date: 2011-03

Variant appearance in text: rs3778151

PubMed Link: 21143246

Variant Present in the following documents:

• Main text

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Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment.

Annals Of The New York Academy Of Sciences

Yuferov, Vadim V; Levran, Orna O; Proudnikov, Dmitri D; Nielsen, David A DA; Kreek, Mary Jeanne MJ

Publication Date: 2010-02

Variant appearance in text: rs3778151

PubMed Link: 20201854

Variant Present in the following documents:

• Main text

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PCA-based bootstrap confidence interval tests for gene-disease association involving multiple SNPs.

Bmc Genetics

Peng, Qianqian Q; Zhao, Jinghua J; Xue, Fuzhong F

Publication Date: 2010-01-26

Variant appearance in text: rs3778151

PubMed Link: 20100356

Variant Present in the following documents:

• Main text
• 1471-2156-11-6.pdf

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A gene-based method for detecting gene-gene co-association in a case-control association study.

European Journal Of Human Genetics : Ejhg

Peng, Qianqian Q; Zhao, Jinghua J; Xue, Fuzhong F

Publication Date: 2010-05

Variant appearance in text: rs3778151

PubMed Link: 20029457

Variant Present in the following documents:

• Main text

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Heroin addiction in African Americans: a hypothesis-driven association study.

Genes, Brain, And Behavior

Levran, O O; Londono, D D; O'Hara, K K; Randesi, M M; Rotrosen, J J; Casadonte, P P; Linzy, S S; Ott, J J; Adelson, M M; Kreek, M J MJ

Publication Date: 2009-07

Variant appearance in text: rs3778151

PubMed Link: 19500151

Variant Present in the following documents:

• Main text

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Genetic susceptibility to heroin addiction: a candidate gene association study.

Genes, Brain, And Behavior

Levran, O O; Londono, D D; O'Hara, K K; Nielsen, D A DA; Peles, E E; Rotrosen, J J; Casadonte, P P; Linzy, S S; Randesi, M M; Ott, J J; Adelson, M M; Kreek, M J MJ

Publication Date: 2008-10

Variant appearance in text: rs3778151

PubMed Link: 18518925

Variant Present in the following documents:

• Main text

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